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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_740_Библиотеки_им_академика_М_И_Перельмана

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Danmark
Sweden
Norway
England
Netherlands
Finland
Scotland
Belgium
Hong Kong
Germany
Australia
Portugal
France
10
20
30
40
50
60
70
80
90
Percentage of outpatient operations for inguinal hernia inPercentage
18 Ambulatory Hernia Surgery
0
177
USA
Fig. 18.2 Percentage of outpatient operations for inguinal hernia in selected countries in 2005 [29]
Table 18.2 Percentage of outpatient operations in
European countries (EHS survey 2016)
Country Proportion in % Sweden 80 Netherlands 75 Portugal 70 Spain 60 England 60 Belgium 40 France 40 Germany 15 Poland 10 Russia 10 Turkey 10 Czech Republic 5 Serbia 5 Ukraine 2 Greece 0 Romania 0
Italy
Spain
gery in percent in the respective countries (Table18.2).
The proportion of outpatient hernia operations thus varies between 0% and 80%. In most coun­tries, however, there is no systematic recording of the operations. In Sweden (Fig.18.3, Table18.3) and Denmark, there are national registries, which record nearly all operations statistically because of state funding. In most other countries, there are only estimates.
Healthcare nancing and reimbursement appear to have a decisive inuence on outpatient surgery. It can be assumed that endoscopic opera­tions cause higher perioperative costs a priori [31]. In Germany, the extremely low proportion of endoscopic procedures in the ambulatory area is due to the fact that outpatient endoscopic ingui­nal hernia surgery is linked to a roughly 20 per
More precise systematic statistics regarding outpatient surgery from the individual coun­tries are lacking. There are usually only studies that consider a short timeframe in individual countries. The European Hernia Society then conducted a survey among the national chap­ters in 2015. This resulted in the following estimates for outpatient inguinal hernia sur-
cent shortfall in funding [32]. At present, there appears still to be a health policy disincentive in Germany [33].
In an international comparison, the reimburse­ment situation for hernia surgery appears to differ substantially (Table 18.4): in numerous coun­tries, there are ambulatory DRGs, which enable outpatient payments to be similar to those in the inpatient area.
178
80%
60%
40%
20%
Operation Year
2015
R. Lorenz
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Man
0%
1995
1994
1993
1992
Fig. 18.3 Proportion of outpatient inguinal hernia operations in Sweden compared by year [30]
Table 18.3 Proportion of outpatient inguinal hernia operations in Sweden compared by year 2006–2015 [30]
Year Outpatient 75.7 76.7 78.1 79.7 78.9 78.5 78.4 79.3 78.1 78.5 Inpatient 24.3 23.3 21.9 20.3 21.1 21.5 21.6 20.7 21.9 21.5
2006 (%)
Women Total
1998
1997
1996
2007 (%)
2008 (%)
1999
2000
2009 (%)
2001
2002
2010 (%)
2003
2004
2005
2011 (%)
2006
2007
2012 (%)
2008
2009
2013 (%)
2010
2011
2014 (%)
2012
2013
2015 (%)
2014
Successful performance of outpatient surgery requires the following:
– Correct indication – Precise preoperative diagnosis – Denition of standardised postoperative
care – Denition of an operation standard – Management of complications – Postoperative pain management with
use of local anaesthetics – Emergency contact
A checklist and handout for patients (What
Table 18.4 International comparison of the reimburse-
ment situation [34]
Country aDRG1 /APC2% of inpatient payment Australia Yes <100% Hungary Yes 100% Portugal Yes 72–100% USA Yes=APC 65–85% Sweden Ye s 100% Italy Yes 80–100% Denmark Ye s 100% Finland Ye s 50–67% Norway Ye s 65–100% Germany No 25% (14–38%)
1
Ambulatory diagnosis relatet groups
2
Ambulatory payment classications
18.5 Practical Requirements andCurrent Data
happens before and after the operation?) can For outpatient surgery, the same structural and stafng provisions should apply as in a hospital.
greatly facilitate the practical implementation of
outpatient surgery.
18 Ambulatory Hernia Surgery
179
From today’s perspective, the following her-
nia types can usually be repaired by day surgery:
– Primary inguinal hernias with and with-
out mesh, open and endoscopic – Recurrent inguinal hernias – Umbilical and epigastric hernias – Small incisional hernias
Inpatient hernia surgery is benecial in the
majority of the following patients:
1. Based on the hernia
– Incarcerated and possibly non-reducible
inguinal hernias – Extensive scrotal hernias – Bilateral hernias or multiple operations – Complex hernia operations, reopera-
tions with mesh explantation – Primary ventral hernias with planned
complex procedures – Secondary ventral hernias = incisional
hernias
2. Because of comorbidities
– Comorbidities with serious secondary
conditions such as stroke, diabetes mel-
litus, CHD, cardiac arrhythmias, renal
failure, severe COPD, anticoagulation
3. Because of the patient’s social situation
– Lack of patient compliance – Lack of aftercare in the night after the
operation
Moreover, supporting quality assurance is
useful.
Based on an initiative by a group of surgeons working in outpatient surgery, the Netzwerk Leistenbruch [Inguinal hernia network] was set up in Germany in 2009, an additional quality assurance study of inguinal hernia operations,
www.netzwerk-leistenbruch.de, which is linked
with Herniamed, the German hernia registry. The Netzwerk Leistenbruch records in particular the early postoperative course 1 and 3months after an inguinal hernia operation and evaluates qual­ity of life independent of the surgeon using the Carolinas Comfort Scale, with a hernia-specic quality of life questionnaire for patients. This showed that very good quality with low recur­rence and chronic pain rates can be achieved in the ambulatory sector [35].
In addition, a univariate analysis of Herniamed data was performed in 2016 to compare outpa­tient and inpatient inguinal hernia operations: in the period from 01.09.2009 to 31.10.2016, a total of 353,271 hernias in 577 centres were recorded in Herniamed, the German hernia registry. A total of 71,751 male, primary, fully documented ingui­nal hernias with complete 1-year follow-up were evaluated for this analysis. There were no signi­cant differences between outpatient and inpatient operations. The intra- and postoperative compli­cations, postoperative pain and recurrences showed no essential differences despite different operation techniques and different patient selec­tion (Table18.5).
Overall, this analysis permits the conclusion that outpatient inguinal hernia surgery can be performed without signicant detriment for the patients. Further analyses, possibly matched pair
Table 18.5 Distribution of intra- and postoperative
complications and follow-up data—outpatient and inpatient [36]
Outpatient %Inpatient
Intraoperative complications 0.61 1.01 Postoperative complications 2.21 2.40 Recurrence on follow-up 0.77 0.90 Rest pain on follow-up 4.01 4.59 Pain with movement on follow-up Pain requiring treatment on follow-up
9.66 8.86
2.23 2.52
%
180
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R. Lorenz
or multivariate, are necessary for comparing out­patient and inpatient operations in detail.
Acknowledgment R.Lorenz declares the following con- icts of interest: C.R. BARD: Consultant for Speakers
Bureau, Hands-On Hernia Training Courses.
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S28. Epub 2013 Oct 8.
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14. Acevedo A, Leon J.Day case hernia surgery under local anaesthesia is feasible and safe in obese patients. Hernia. 2010;14:57–62.
15. Pere P, Harju J, Kairaluoma P, Remes V, Turunen P, Rosenberg PH.Randomized comparison of the feasi­bility of three anesthetic techniques for day-case open inguinal hernia repair. J Clin Anesth. 2016;34:166–
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1):S93–6. https://doi.org/10.1016/j.ijsu.2008.12.012. Epub 2008 Dec 13.
17. Ngo P, Pélissier E, Levard H, et al. Ambulatory groin and ventral hernia repair. J Visc Surg. 2010;147(5):e325–8. Epub 2010 Oct 14.
18. Lorente-Herce JM, et al. Incisional hernia repair in an ambulatory surgery-extended recovery cen­tre: a review of 259 consecutive cases. Hernia. 2015;19(3):487–92.
19. Wirth U, Saller ML, von Ahnen T, Köckerling F, Schardey HM, Schopf S.Inguinal hernia repair in TAPP technique in a day-case surgery setting—at what price? Chirurg. 2017;88(9):792–8. https://doi.org/10.1007/
s00104-017-0429-9. [Epub ahead of print].
20. Simons MP, Aufenacker T, Bay-Nielsen M, Bouillot JL, Campanelli G, Conze J, de Lange D, Fortelny R, Heikkinen T, Kingsnorth A, Kukleta J, Morales-Conde S, Nordin P, Schumpelick V, Smedberg S, Smietanski M, Weber G, Miserez M. European Hernia Society guidelines on the treatment of inguinal hernia in adult patients. Hernia. 2009;13(4):343–403.
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21. Miserez M, et al. Update with level 1 studies of the European Hernia Society guidelines on the treat­ment of inguinal hernias in adult patients. Hernia. 2014;18:151–63.
22. HerniaSurge Group. International guidelines for groin hernia management. Hernia. 2018;12:1–165. doi:
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23. Dholakia S, Jeans JP, Khalid U, Dholakia S, D’Souza C, Nemeth K.The association of noise and surgical­site infection in day-case hernia repairs. Surgery. 2015;157(6):1153–6.
2014.12.026. Epub 2015 Feb 28.
24. Frassanito L, Pitoni S, Gonnella G, Aleri S, Del Vicario M, Catarci S, Draisci G.Utility of ultrasound­guided transversus abdominis plane block for day­case inguinal hernia repair. Korean J Anesthesiol. 2017;70(1):46–51. https://doi.org/10.4097/
kjae.2017.70.1.46. Epub 2016 Oct 25.
25. Jarrett PEM. Day care surgery. Eur J Anaesthesiol. 2001;18(S23):32–5. https://doi.org/10.1046/j.1365-
2346.2001.018s23032.x.
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26. McCormack K, Scott NW, Go PM, Ross S, Grant AM.Laparoscopic techniques versus open techniques for inguinal hernia repair. Cochrane Database Syst Rev. 2003;(1):CD001785. https://doi.org/10.1002/
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27. Rodriguez-Cuellar E, Villeta R, Ruiz P, etal. National project for the management of clinical processes. Surgical treatment of inguinal hernia. Cir Esp. 2005;77(4):194–202. doi: 13073287.
28. Holzheimer RG.First results of Lichtenstein hernia repair with Ultrapro-mesh as cost saving procedure— quality control combined with a modied quality of life questionnaire (SF-36) in a series of ambulatory operated patients. Eur J Med Res. 2004;9(6):323–7.
29. Toftgaard C, Parmentier G.International Association for Ambulatory Surgery (IAAS). 2005.
30. Swedish Hernia Register—Report. 2015. http://www.
svensktbrackregister.se/images/stories/doc/verksam­hetsberattelser/rapport15_160517.pdf.
31. Cariati A, Piromalli E.Cutting costs in inguinal hernia surgery: laparoscopic or ambulatory (or 1-day) open hernia (Lichtenstein) repair? Indian J Surg. 2013;75(5):
409. https://doi.org/10.1007/s12262-012-0599-0.
32. Weyhe D, Winnemöller C, Hellwig A, Meurer K, Plugge H, Kasoly K, Laubenthal H, Bauer KH, Uhl W. (section sign) 115 b SGB V threatens outpatient treat­ment for inguinal hernia. Analysis of outcome and economics. Chirurg. 2006;77(9):844–55. Brökelmann J.BAO-Depesche Nr. 19, Dez. 2009, 18–19.
33. Schulz G. Kosten und Erlöse des Ambulanten Operierens. Ambulant Operieren. 2008;2008:125–30.
34. Brökelmann J.Ambulant Operieren 4/2000. p.199.
35. Koch A, Lorenz R, Meyer F, Weyhe D.Hernia repair at the groin—who undergoes which surgical interven­tion? Zentralbl Chir. 2013;138(4):410–7.
36. Lorenz R.Unpublished data from the German Hernia Database Herniamed—Chirurgische Praxis, 2017, in press.
Obscure Groin Pain inWomen
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ShirinTowgh
19
19.1 History oftheHidden Hernia
The concept of hidden hernias was rst intro­duced in the 1970s by two separately inter­ested surgeons from the United States: William Webb from Alabama and Jack Herrington from Wisconsin. They each noticed that women were presenting with symptoms suggestive of ingui­nal hernia; however, the surgeons had a hard time diagnosing hernia on physical examination. Their patients reported intermittent pain along the inguinal canal that was related to physi­cal activity. However, the physical examination was essentially normal and “without detectable impulse.”
Webb reported his experience with 12 women who had symptomatic inguinal hernias without diagnostic examination ndings. Physical exami­nation was mostly normal. He offered them an exploration based on their history alone. They presented similar to most other symptomatic inguinal hernias: groin pain radiating along the inguinal canal. He found that these women typi­cally had small indirect inguinal hernias with preperitoneal fat content only. There was no her­nia sac. Repair was successful in all the patients, with resolution of their preoperative pain.
S. Towgh, MD, FACS Beverly Hills Hernia Center, Beverly Hills, CA, USA e-mail: drtowgh@beverlyhillsherniacenter.com
Over a 5-year period of time, Herrington operated on 13 such patients (8% of his prac­tice), all of whom were also women. They suf­fered with groin pain of undiagnosed etiology. Mean age was 20 years (15–45). Most had undergone a wide range of gastrointestinal, uro­logic, and gynecologic workups. Operative nd­ings were of the typical indirect inguinal hernia, and most had a peritoneal sac. At 10 months follow-up, ten (77%) patients had a cure of their symptoms after open inguinal hernia repair, and three patients had signicant improvement. He referred to these as “female occult inguinal her­nias” and urged their early diagnosis, as hernia repair was curative.
The concept of the non-palpable, symptom­atic, occult, or hidden hernia did not become popular despite these groundbreaking reports. Textbooks continued to report 25% lifetime risk of inguinal hernias among males and only 2% risk among females. It wasn’t until Bendavid’s textbook of Abdominal Wall Hernias that this topic was readdressed in the twenty-rst century.
Similar to their predecessors, Spangen and Smedberg reported on 180 women in an 18-year span with 192 occult hernias. Most were found to have typical inguinal hernias with peritoneal sac. However, 57 (30%) had inguinal hernias with preperitoneal fat content only and no peri­toneal extension within the inguinal canal. They had successful outcomes after hernia repair, with relief of preoperative symptoms in 89% of patients, with mean 20 (1–60) months follow-up.
© Springer International Publishing AG, part of Springer Nature 2018 G. Campanelli (ed.), The Art of Hernia Surgery, https://doi.org/10.1007/978-3-319-72626-7_19
183
184
S. Towgh
19.2 Anatomical Explanation fortheHidden Hernia
Women naturally have a narrower inguinal canal than men. Essentially, it contains a thin round ligament and perhaps the genital branch of the genitofemoral nerve. Conversely, males begin with a naturally wider inguinal canal that houses the spermatic cord. Meanwhile, the female pelvis is broader and shallower. As a result, the insertion of the internal oblique and transversus abdominis muscles is broader along Cooper’s ligament and further onto the rectus muscle. Also, the round ligament pierces the abdominal wall more later­ally and follows a more oblique path within the inguinal canal. Lastly, the natural forces from gravity and from internal abdominal pressure are distributed more evenly along the pelvic oor, as compared to that in the narrow pelvis of men.
As a result, women tend not to present with wide palpable defects or signicant bulging from their hernia. Instead, they present with groin pain, sometimes with the very smallest amount of preperitoneal fat entering the narrow inguinal canal.
On physical examination, men typically have a palpable if not visible bulge. When standing, an impulse may be generated by Valsalva or cough. Using the redundancy of the scrotal skin, the spermatic cord can be followed toward the exter­nal ring, and the rest of the pelvic oor in this region can be directly palpated. In women, there is no direct access to the external ring and the inguinal canal contents. Palpation is made directly over the inguinal canal at the level of the skin. Any hernia must be noted through the layers of skin, soft tissue, and external oblique aponeu­rosis. If a vaginal examination is performed, the examiner can sometimes detect a mass via the vaginal sidewall. This is another reason for the occult non-palpable hernia.
19.3 Symptoms inWomen
Hernias among women tend to present with a wide variety of symptoms. As many of these symptoms are not similar to those typical of men,
it can delay their diagnosis. In my practice, I have shown that the typical hernia was diagnosed by me after 20 weeks of presentation. Those with hidden hernias averaged 96weeks of symptoms. Typically, the dominant symptoms for hernias among women are activity-related, such as pain with lifting heavy objects. Normal daily routines that cause increased pressure onto the inguinal canal may also cause pain, such as prolonged sit­ting, prolonged standing, and bending. The pain is often worse at the end of the day. Pain may also be distributed along the distribution of the ilioin­guinal and genital nerves, and this can be misin­terpreted as primary neuropathic pain. In my experience, some of these patients undergo local nerve block to address the neuropathic pain. If a hernia is the cause of the neuropathic type pain, I have noted that patients report an increase in their groin pain after the nerve block, whereas a nerve block should improve pain in the case of a true primary nerve injury without a hernia.
Though men do not typically present with pain as their primary complaint from their ingui­nal hernia, such is not the trend with women. Among women, groin pain is often the rst pre­senting symptom. Many surgeons are trained to believe that pain alone cannot be due to an ingui­nal hernia. This may be true among most male patients; it is not the case in women. As a result, many women are labelled as having chronic pel­vic pain, and inguinal hernia is not considered to be the cause of their groin pain.
As we already know, smaller hernia defects tend to present with more pain and less bulging, whereas larger hernia defects tend to present with a bulge without as much pain. So it may be the case that women with inguinal hernias, many of which are hidden hernias, present with pain as their original symptom and not with a palpable bulge. The patient may complain of radiating pain, which I found to be seen among almost half (48%) of my patients (Table19.1). This includes pain radiating pain from the groin into the vagina, to the upper inner thigh, to the anterior thigh— but never below the level of the knee—and/or wrapping around laterally toward the hip and back. In my experience, 20% of patients have associated lower back pain that resolves after
19 Obscure Groin Pain inWomen
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185
hernia repair. Such patients may be misdiagnosed with spinal pathology. Notably, patients with lower back pain do not have groin pain, with the exception of sacroiliitis, which can cause pain radiating from the back to the groin and upper inner thigh.
Also, 39% of my female patients have radiat­ing pain into the vagina (Table19.1). This is anal­ogous to the pain radiating to the base of the penis and/or testicle in men. Such a complaint can trigger a gynecologic workup of obscure diagnoses such as vulvodynia, pudendal neural­gia, and chronic pelvic pain. These diagnoses often have complex syndromes that are not seen among patients with inguinal hernia.
Symptoms unique to women include pain dur­ing menses. In my practice, 25% of women with symptomatic inguinal hernias report exacerba­tion of their symptoms during their menses (Table19.1). This is considered to be due to uc­tuations in hormones. As estrogen levels plum­met at the onset of menstruation, pain levels increase. This phenomenon has been shown in multiple other disease processes, including joint disorders, autoimmune disorders, and gastroin­testinal diseases. In such cases, women are com­monly worked up for endometriosis, which is a cyclical disease. Unlike endometriosis, hernias are not pain-free in between menstrual periods.
Table 19.1 Key history and examination ndings pre-
dictive of female symptomatic occult inguinal hernia, with expected outcomes after hernia repair
Symptoms Prevalence Pain as primary symptom 87% Radiating quality to the groin pain 48% – Radiating pain to the vagina 39% – Radiating pain to lower back 20% Worse with menses 25% Pain during intercourse Pain with orgasm
Examination ndings
Point tenderness over deep internal ring 96–100% Hyperalgesia along ilioinguinal nerve 63% Subtle fullness overlying inguinal canal 52% Pelvic oor spasm
Operative ndings
Preperitoneal fat only, no hernia sac >30% Signicant improvement in preoperative symptoms after hernia repair
78–87%
In women, hernias can be painful during sex­ual intercourse as well as with orgasm. The rea­son for pain with intercourse is often a simple phenomenon of direct contact and pressure on the groin. Similarly, vaginal penetration can cause pain by direct pressure onto the external ring, which we noted earlier could be palpable transvaginally. Pain with orgasm is considered to be due to pelvic oor contraction against a full inguinal canal.
19.4 Subtle Physical Examination
Findings
The concept of the occult inguinal hernia is based on the nding of a symptomatic inguinal hernia without obvious ndings on physical examina­tion. This includes no visible bulge and no detect­able impulse. For example, a cough or Valsalva will typically not generate a bulging mass on external examination in this population. That said, in my experience, 96% of these patients have point tenderness at the level of the internal ring upon direct pressure. Spangen similarly reported 100% with point tenderness overlying the deep internal ring upon Valsalva. He also reported 63% with hyperalgesia along the ilioin­guinal nerve distribution (Table19.1).
With a very sensitive touch, the examiner can feel a subtle fullness in the area overlying the deep internal ring among those with a symptom­atic hidden hernia. I have noted this in 52% of my patients with symptomatic occult inguinal her­nias. This represents content and probably inammation in the area of the inguinal canal. It is also often tender over the same area. If this area of vague fullness correlates with the area of pain, which correlates with the area over the deep internal ring, we have shown this to be the most sensitive predictor of a hidden hernia (Fig.19.1).
Many women are rst evaluated for their groin pain by their gynecologist. Pelvic exam can be painful on the side of the inguinal hernia. There may be nding of pelvic oor spasm as well. Some patients are referred to pelvic oor physi­cal therapy for this reason. In my experience, I have noted that such therapy exacerbates the
186
Fig. 19.1 Area of maximal tenderness and vague fullness
notable in patients with symptomatic occult inguinal her­nias. This area is approximately halfway between the anterior superior iliac crest and pubic tubercle on each side
patient’s pain if she has an inguinal hernia and not primary pelvic oor dysfunction. Also, I have noted that the pelvic oor spasm resolves after successful inguinal hernia repair.
Thus, I have come to the conclusion that inguinal hernias can cause pelvic oor spasm in women. This results in the sequelae seen with this entity, including chronic pelvic pain, pain with sexual intercourse, urinary frequency, feel­ing of pain, or pressure at the vagina or rectum. The workup and treatment can be highly varied, and patients may be misdiagnosed with intersti­tial cystitis or pelvic oor dysfunction. These dis­orders are multifactorial and are dened by a series of objective ndings, such as with cystos-
S. Towgh
copy or dynamic pelvic imaging, respectively. The workup would be normal in those with ingui­nal hernia.
Conclusion
Women can have inguinal hernias, and it is much more prevalent than we are led to believe historically. Women are more likely than men to present with groin pain without bulging mass, hence the term female occult inguinal hernia or hidden hernia. Carefully listening to the patient will allow the examiner to identify key details in their history that are suggestive of inguinal hernia. The most sensitive exami­nation nding is that of point tenderness over the area of the deep internal ring. Operative ndings may show preperitoneal fat content only, without peritoneal extension.
As more attention is placed on this entity, more women will be diagnosed, without delay, with a potential for improvement in their qual­ity of life.
Suggested Readings
1. Fodor PB, Webb WA.Indirect inguinal hernia in the female with no palpable sac. South Med J. 1971;64:15.
2. Herrington JK. Occult inguinal hernia in the female. Ann Surg. 1975;181:481–3.
3. Neumayer L, Towgh S.Inguinal hernia. In: Cameron JL, Cameron AM, editors. Current surgical therapy. 11th ed. NewYork: Elsevier; 2013. p.531–6.
4. Rutkow IM. Epidemiologic, economic, and socio­logic aspects of hernia surgery in the United States in the 1990s. Surg Clin N Am. 1998;78:941–51. v–vi.
5. Saad CA, Kim DS, Solnik MJ, Towgh S. Inguinal hernia as a cause of chronic pelvic pain: a key sign to make the diagnosis. Obstet Gynecol. 2015; 125:70S.
6. Spangen L, Smedberg SGG. Nonpalpable inguinal hernia in women. In: Bendavid R, Abrahamson J, Arregui ME, etal., editors. Abdominal wall hernias. NewYork: Springer; 2001. p.625–9.
7. Zarrinkhoo E, Towgh S, Miller J.Hidden hernias as a cause of chronic pelvic pain. Hernia. 2015;19:S73–6.
Individualization Treatment
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ofInguinal Hernia inChildren
JieChen, YingmoShen, ChengbingChu, ZhenyuZou, andXinYuan
20
The incidence of inguinal hernia in children less than 18years of age ranges from 0.8 to 4.4% [1]. About 85% of children with an inguinal hernia present with a unilateral hernia. The incidence of incarceration in untreated hernias in infants and young children varies between 6 and 18%, but it increases to approximately 30% in infancy [2]. A surgical intervention for inguinal hernia is one of the most common operations performed in chil­dren [3]. The individualized treatment program was established for pediatric inguinal hernia in authors’ department and provided a relatively reasonable surgical treatment. This chapter was mainly to describe the individualized treatment program applied to pediatric inguinal hernia.
20.1 Etiology
Indirect inguinal hernias in children are basically caused by embryologic development, which is mainly composed of patency of processus vagi­nalis (Fig.20.1). At the early stage of gestation, the testes begin to descend from retroperitoneum and remain at the level of the internal inguinal rings as the kidney ascends into its usual position. The nal descent of the testes into the scrotum through canalis inguinalis occurs between gesta-
tion weeks 28 and 36 [4], combining peritoneum, transversalis fascia, and abdominal wall muscles. The testes’ descent is “guided” by the gubernacu­lums. Descending peritoneum ultimately forms the processus vaginalis, and the distal portion of the processus vaginalis wrapping around testes becomes the tunica vaginalis. In normal develop­ment, the processus vaginalis closes between 36 and 40weeks of gestation or even shortly after birth [5]. The rate of patency is inversely propor­tional to the age of children, approximately 80% close by 2years of age [4]. The left testis descends before the right one, and the closure of patent processus vaginalis on the left also precedes clo­sure on the right; therefore, indirect inguinal her­nia occurs more on the right side.
Though the embryology has been widely described, the cell-molecular mechanism is still unclear. The inguinal hernias most probably are inherited [6]. Yu Zhang etal.’s team have found that the functional sequence variants of some genes may be a risk factor for indirect inguinal hernia, such as gene TBX1, gene TBX3, gene SIRT1, and gene GATA6. These variants may affect the differentiation and proliferation of human skeletal muscles and broblasts [710].
20.2 Clinical Manifestation
J. Chen (*) · Y. Shen · C. Chu · Z. Zou · X. Yuan Department of Hernia and Abdominal Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
© Springer International Publishing AG, part of Springer Nature 2018 G. Campanelli (ed.), The Art of Hernia Surgery, https://doi.org/10.1007/978-3-319-72626-7_20
A reducible bulge or mass in the inguinal region or unilateral or bilateral enlargement of the scro­tum (Fig.20.2a, b) is the main diagnostic nding
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