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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5775_Библиотеки_им_академика_М_И_Перельмана

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Appropriatedescriptorsoftheabnormalityinclude:
A.ColumnofBertin B.Encapsulated C.Peripheral D.Infiltrative
ANSWERSANDEXPLANATIONS
1.  AnswerC.  Sagittal images of both kidneys show generalized increased echogenicity of the renal
pyramids and associated posterior acoustic shadowing, consistent with calcium deposition. Color Dopplerimageoftherightkidneyshows“twinkle”artifactfromtherenalcalcifications.Thefindingsare consistent with medullary nephrocalcinosis. The common causes of medullary nephrocalcinosis in the orderoffrequencyareasfollows:40%,primaryhyperparathyroidism;20%,renaltubularacidosistypeI; and 20%, medullary sponge kidney. Other causes such as hypervitaminosis D states and milk–alkali syndrome are less common. Chronic glomerulonephritis results in cortical nephrocalcinosis (and not medullarynephrocalcinosis).
References:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:130–131.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:346–348.
2a. AnswerA. Bladder cancer isusuallyseen as a sessile or pedunculated mass projecting intothe
bladderlumen.Immobilityandpresenceofinternalvascularityareusefuldistinguishingfeatures.Fungus ballsandbloodclotsare mobile masseswithoutvascularity. Bladder stonesaremobileand echogenic andshowposterioracousticshadowing.
2b.  Answer B.  Approximately 90% of bladder tumors are transitional cell carcinoma (TCC). The
majority of TCCarise at the trigoneand along the lateral andposterior bladder walls. Squamouscell carcinomasaccountfor5%to8%ofallbladdertumors.Adenocarcinomaofthebladderisrare(~2%of all bladder tumors) and tends to occur in urachal remnants and in bladder exstrophy. Neuroendocrine (smallcell)tumorofthebladderisrarer,accountingfor<0.5%ofallbladderneoplasms.
2c.  Answer A.  The pathogenesis for urothelial tumors is direct prolonged contact of the bladder
urotheliumwithurinecontainingexcretedcarcinogens.Themostwell-establishedriskfactorforbladder canceriscigarettesmoking.Cigarettesmokingaccountsforone-thirdtoone-halfofallcasesofbladder cancer. There is also a well-documented causal link between urothelial cancer and a variety of occupational and environmental chemicals such as aniline, benzidine, aromatic amines, and azo dyes. Therefore,occupationalexposure tochemicalcarcinogensisthesecondmostimportantriskfactorafter smoking,estimatedtoaccountforasmuchas20%ofallbladdercancer.Chronicirritationfrombladder calculiandrecurrenturinarytractinfectionsisstronglyassociatedwithsquamouscellcarcinoma.
References:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:167–168.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:359–360.
Wong-You-CheongJJ,WoodwardPJ,ManningMA,etal.Neoplasmsoftheurinarybladder:radiologic-pathologiccorrelation.Radiographics 2006;26:553–580.
3.AnswerC.Abilobedthin-walledanechoicadrenallesioncontainingathinseptationwithnointernal
colorDopplersignalisshown.Athinsmoothwallandlackofasolidcomponentfavorsanadrenalcyst, pseudocyst, or parasitic cyst. Whereas true adrenal cysts are lined by endothelium, pseudocysts are surrounded by a fibrous capsule and are usually the sequelae of adrenal hemorrhage or infection. In addition,neoplasmsincludingadrenocorticalcarcinoma,pheochromocytoma,andadenomasmayundergo necrosis or degeneration leading to cystic components, which may be extensive especially in larger tumors. Careful inspection on contrast-enhanced CT or MRI should be performed to exclude a solid tumoralcomponent.Therehaveonlybeenafewreportedcasesofentirelycysticpheochromocytoma.
References:NewhouseJH,HeffessCS,WagnerBJ,etal.Largedegeneratedadrenaladenomas:radiologic-pathologiccorrelation.Radiology 1999;210(2):385–391.
LeeTH,SlywotzkyCM,LavelleMT,etal.BestcasesfromtheAFIP.Radiographics2002;22(4):935–940.
4a.  AnswerD. A large echogenic suprarenal massis shown with associated impairmentof acoustic
penetration,indicatingthepresenceoffat.Althoughgascanresultin“dirty” acousticshadowing,linear high-amplitudereflectionsareexpectedalongtheboundaryclosesttotheprobe.Bloodproductscanhave a variety of appearances but would not be expectedto shadow.Large calcifications typically produce cleanacousticshadows.
4b.  Answer B.  The average velocities of sound in fat and soft tissue are 1,450 and 1,540 m/s,
respectively. Speed errors result when the actual propagation speed through a tissue varies from the calibratedvelocityusedbythesystem(1,540m/s).Thisleadstoinaccuratemeasurementsbetweentissue boundaries. As a result of slower propagation of sound through the fatty mass, the portion of the diaphragm–lunginterfacedeeptothemyelolipoma(yellowline)isincorrectlypositionedfurtherfromthe probethantheadjacentinterfacedeeptotheliver(whiteline).Althoughthediaphragm–lunginterfaceis smoothandcontinuousinreality,ittakesonanartifactualstair-steppedappearanceonultrasound.
4c.  Answer A.  Although renal cell carcinomas may contain fat (from lipid-producing necrosis,
intratumoralosseousmetaplasiawithfattymarrowelements,andentrapmentofperirenalorsinusfat),we wouldnotexpectthemtobecomposedprimarilyoffat.Renalangiomyolipomas,adrenalmyelolipomas, andretroperitoneal liposarcoma can be mostly or purely composed of fat on imaging. There are case reportsofadrenalcorticalcarcinomacontainingmacroscopicfat,butinvirtuallyallcases,thepresence ofmacroscopicfatwithinanadrenalmasspermitsadiagnosisofabenignlesion.
4d.AnswerA.Thereisnorecognizedmalignantpotentialforadrenalmyelolipomas.
References:KenneyPJ,WagnerBJ,RaoP,etal.Myelolipoma:CTandpathologicfeatures.Radiology1998;208(1):87–95.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:3–4.
5.AnswerC.Rootcauseanalysisisastructuredmethodborrowedfromanalysisofindustrialaccidents
to evaluate serious adverse events. It is a comprehensive process requiring data collection, event reconstruction,recordreview,andinterviews.Bothactiveerrors,thoseleadingdirectlytotheevent,and latent errors, hidden errors within the health care system contributing to the error, are studied. This information isanalyzedbya multidisciplinaryteam todetermine howandwhy the event occurred. The ultimategoal ofRCAis toeliminate the variouslatenterrors, which contribute toanincreased risk of similarfutureerrors.Ratherthanasinglerootcause,oftenadverseeventsarecausedbymultipleerrors andsystemflaws.
Reference: AmericanBoard of Radiology.Quality and Safety Domain Specification and Resource Guide, Core Exam Study Guide. Tucson,AZ:ABR,2016:28.
6.AnswerD.Between2004and2014,therewere1,072reportsofwrong-patient,wrong-site,wrong-
procedure sentinel events, representing the largest category. Radiation overdoses, anesthesia-related eventsandmedicationerrorsaccountedfor36,104and428events,respectively.
Reference: AmericanBoard of Radiology.Quality and Safety Domain Specification and Resource Guide, Core Exam Study Guide. Tucson,AZ:ABR,2016:26.
7a.AnswerD.ImagesshowaFoleyballoonposteriortothebladderwithcatheterextendingcaudallyin
thevagina.
Bladder diverticula typically occur in the setting of bladder outlet obstruction. Connection to the bladderis usuallyseensonographically.Urethraldiverticulaarisefromandare immediately associated withtheurethra.Theyarebestseenonultrasoundbytransvaginalortransperinealimaging.Ureteroceles areformedfromcysticdilatationoftheintravesicalsegmentoftheureter.Onultrasound,theyappearas cysticstructuresintheposterolateralbladder(expectedinsertionofureter).Urachalcystsoccurbecause ofincompleteclosureoftheurachusandare therefore locatedalongtheanteriorandsuperioraspectof the bladder.AlthoughGartnerductcystsare located in thislocation(anterior lateral vagina abovethe pubicsymphysis),thestructureshowninthisimageisclearlyaFoleycatheterwithballooninthemidline vaginaandcathetersegmentextendingthroughtheballoonandcaudallyinthevagina.
7b.AnswerA.90%oftumorsthatarisewithinaurachalremnantareadenocarcinoma.
7c. AnswerA. Gartnerductcystsare typicallylocated intheanterior lateralvaginalwallabove the
pubicsymphysis.Theymaybeseeninassociationwithotherwolffiananomaliessuchasrenalagenesis and ectopic ureter. Urethral diverticula can be confused with Gartner duct cysts because of similar locationandappearance.Urethraldiverticulawillshowdirectcommunicationwiththeurethra.Bartholin ductcystsare located in theposterior lateral inferior third of the vagina below thelevel of the pubic symphysis.Nabothiancystsarelocatedwithinthewallofthecervix.
References: Berrocal T, López-Pereira P,Arjonilla A, et al. Anomalies of the distal ureter, bladder, and urethra in children: embryologic, radiologic,andpathologicfeatures.Radiographics2002;22(5):1139–1164.
Chaudhari VV, Patel MK, Douek M, et al. MR imaging and US of female urethral and periurethral disease. Radiographics 2010;30(7):1857–1874.
YuJ-S,KimKW,LeeH-J,etal.Urachalremnantdiseases:spectrumofCTandUSfindings.Radiographics2001;21(2):451–461.
8.AnswerA.Spatial compoundingcombinesimagesobtainedfromdifferentscananglesintoasingle
frame.Byutilizingmultiplescanangles,lesionmarginsarebetterdelineatedbecausemoreofthelesion marginiscloseto90degreestotheultrasoundbeam.Orientationofaspecularreflector90degreestothe beammaximizestheamountofreflectedacoustic energyreturningtothe probe,leadingtomoredistinct boundariesforcystsandothermasses.Additionally,althoughdesirableacousticinterfacessuchasthose foundinrenalcystsarereinforcedthroughthesummingoftheimages,randomlylocatedspecklenoiseis notreinforced,resultinginasignificantlyincreasedsignal-to-noiseratio.
Reference: Rumack CM, Wilson SR, Charboneau WJ. Diagnostic ultrasound, 4th ed. Philadelphia, PA: Elsevier Health Sciences, 2011:14–16.
9.AnswerA.Sidelobesarelocatedoutsideoftheprimarydesiredacousticbeambutmayinteractwith
tissues and return as an echo to the probe, thus creating artifactual low-level echoes, which are best appreciatedwithinanechoiccysticandfluid-filledstructures.Forexample,side-lobeartifactcanresultin theappearanceofgallbladdersludge.
Reference:RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:17.
10a.AnswerC.Theimagesshowahomogeneouslyechogeniclesionattheupperpoleoftheleftkidney,
withamaximaldiameterofslightly<3cm.Theimagingfeaturesarecharacteristicofanangiomyolipoma. AMLsarebenigntumorscomposedofdysmorphicvessels,smoothmuscle,andmaturefat.Eightypercent are sporadic, mostfrequentlyin middle-aged women, andtheother20% are associatedwith tuberous sclerosis(TS).PatientswithTSoftenhavementalretardation,seizures,andfacialsebaceousadenomas. Therefore,Cisthecorrectanswer.NoneoftheotherchoicesareassociatedwithTS.
10b.  Answer B.  Although a homogeneous, highly echogenic mass is very suggestive of AML,
approximately10%ofrenalcellcarcinoma(RCC)canmimicthisappearance.Onedistinguishingfeature seeninupto30%ofAMLsisacousticshadowing,whichisextremelyrareinRCC.Hyperechoicmasses that show no acoustic shadowing require further characterization with CT or MRI to demonstrate fat. Choice B is the correct answer. Choice A is not correct because the lesion is neoplastic, not inflammatory.ChoiceCwouldnotbethemostappropriatenextstepbecausethelesionisstatisticallyan AML,andconfirmation of fatis likelyall that is needed. Although bleeding is a seriouscomplication relatedtoAMLs,itisrarewhenthelesionsare<4cm.Therefore,choiceDisincorrect.
Reference:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:122–123.
11a.AnswerD.Theimagesshowanabsentkidneyintherightrenalfossa.Therearetwonormal-sized
kidneysbroadlyfusedtogetherintheleftrenalfossa.Atrealtime,thekidneysinthispatientextendedinto theleftlowerpelvis.Apelvicrightkidney(choiceA)isincorrectbecausepelvickidneysarenotfusedto the contralateralkidney. Theyremain ontheipsilateral sideof the bodybutare found more inferiorly. Horseshoekidneysareusuallyfusedatthelowerpolesandlocatedmoreinferiorlythannormal,buteach renalmoiety will remain in the correctside ofthe body(optionB). Diffuse compensatory hypertrophy resultsin ipsilateralrenalenlargementwhen thecontralateral kidneyisabsent or dysfunctional(option
C), particularly when the renal insultoccurs in utero or early in life. The right kidney in this case is presentandnormalappearing,butisabnormallypositioned.
11b. Answer C.  Crossed renal ectopia occurs when there is in utero fusionof the metanephrogenic
blastema,notallowingforproperrenalrotationorascent.Theureterovesicaljunctionsarenotaffected, andbothareinnormalanatomicallocation.Thisisusefultorememberwhenthesepatientspresentwith renalcolic.
References:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:103–106.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:324.
12.AnswerA.Thetwobroadcategoriesofradiologisterrorareperceptualandcognitive(interpretive)
errors.Perceptualerroroccurswhenanabnormalitythatcanbeseeninretrospectwasnotidentifiedby the interpreting radiologist at the time of the initial interpretation. “Satisfaction of search,” in which identification of one abnormality results in a second abnormality being overlooked, is one of many potential causes ofperceptualerror.Perceptualerrors accountfor 60% to80% ofradiologists’errors. Cognitiveerroroccurswhentheradiologistidentifiesafindingbutrendersanincorrectinterpretation.
Reference: AmericanBoard of Radiology.Quality and Safety Domain Specification and Resource Guide, Core Exam Study Guide. Tucson,AZ:ABR,2016:26.
13.AnswerB.Theultrasoundshowsashadowingstonethatwasglimpsedonthesagittalandtransverse
viewsintheproximaltransplantureterresultinginmildhydronephrosis.Thisismostlikelythecauseof the elevated creatinine level. The ultrasound images also reveal a simple-appearing deep perinephric collectionneartherenalvein.AlthoughcolorDoppleraliasingandperhapssomeluminalcompressionof therenalveinmaybepresent,anglecorrectionwasnotappliedandavelocitygradientwasnotmeasured, so the provided images are not sufficient to diagnose severe renal vein stenosis (option A). The perinephric fluid collection shown remained stable 1 year later and was thought to represent a lymphocele. Subcapsular hematoma and solid masses, as can be seen with posttransplant lymphoproliferativedisease,areabsent(optionsCandD).
The clinical diagnosis ofobstructive uropathyafter renal transplant isdifficult becausethe graft is denervatedandpatientsareasymptomatic.Thediagnosismayremainunsuspecteduntilhydronephrosisor decliningrenalfunctionisdiscoveredincidentally.Mild,nonobstructivepelvicaliectasisiscommonafter renaltransplant.
References: Rhee BD, Bretan PN Jr, Stoller ML. Urolithiasis in renal and combined pancreas/renal transplant recipients. J Urol 2005;161(5):1458–1462.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:679–681.
14.  Answer A.  Sonography is often used as a screening tool in patients presenting with elevated
creatininetoruleoutunderlyingmechanicalobstruction.Lackofobstructionusuallyindicatesthatrenal parenchymaldiseaseispresent.Sonographicappearanceofvariousrenalparenchymaldiseases suchas acutetubularnecrosis,glomerulonephritis,andacuteinterstitialnephritisaffectingthekidneysisdifficult todistinguishon ultrasound. Patientsoftenpresentwithdiffuselyechogenickidneys, andbiopsymaybe neededinselectpatientstoestablishaspecificdiagnosis.Theimagesshowamildlyenlarged,strikingly echogenic cortex relative to the spleen (when the spleen is used as an external control) and the hypoechoicrenalpyramids(whenusedasaninternalcontrol).
The colorDoppler imageof the renalveinconfirms patency, andthereisnodilatation oftherenal pelvis(choicesBandCareincorrect).Thehypoechoicrimaroundthekidneyrepresentsperinephricfat, which appears hypoechoic relative to the echogenic renal cortex. Diffuse xanthogranulomatous pyelonephritisdoesnothavespecificsonographicfeaturesbutcanbesuggestedwhenrenalenlargement, corticalthinning, dilated, debris-filled calyces, largecalculi, andperinephric fluidare present (option D). This particular patient had a known history of idiopathic membranous glomerulonephritis, an autoimmunedisease.
References:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:131–132.
MakkerSP,TramontanoA.Idiopathicmembranousnephropathy:anautoimmunedisease.SeminNephrol2011;31(4):333–340.
RumackCM,WilsonSR,CharboneauWJ.Diagnosticultrasound,4thed.Philadelphia,PA:ElsevierHealthSciences,2011:380–382.
15.  Answer B.  Sagittal ultrasound image of the left lower quadrant renal allograft shows a large
anechoic peritransplant fluid collection with few internal septations. This most likely represents a peritransplant lymphocele. Lymphoceles arethemostcommonfluidcollectionsseen in renal transplant recipients. They typically occur 1 to 3 weeks following surgery. They maybe asymptomatic or cause localpainandtenderness.Septationsmaybeseenwithinlymphoceles,asinthiscase.Lymphocelesform fromleakageoflymphfromrecipientlymphaticchannels.Largelymphocelesmayresultinimpairedgraft function.
Urinomasaremuchlesscommon.Theyoccurbecauseofbreakdownoftheureterimplantationintothe bladder. Therefore, they are usually in close proximity to and may exert mass effect on the bladder. Hematomasarecommonintheearlypostoperativeperiod.Smallhematomasmaybeseenincidentallyat imaging.Largehematomasmayresultinpain.Atultrasound,hematomasusuallyappearasheterogeneous perinephric collections. Abscesses typically appear as complex fluid collections containing internal debris.
References:HertzbergBS,MiddletonWD.Ultrasound:therequisites,3rded.Philadelphia,PA:Elsevier,2016:140–141.
MorenoCC,MittalPK,GhongeNP,etal.Imagingcomplicationsofrenaltransplantation.RadiolClinNorthAm2016;54(2):235–249.
16a.AnswerB. Theimages showanovoid circumscribed cysticlesioncontaininglow-levelinternal
echoes within the wall of the upper vagina. There is posterior acoustic enhancement and no internal vascularity.Thetransvaginalprobeindentsthemass.
Thewolffian(mesonephric)ducts,embryologicprecursorstothevasdeferensandseminalvesicles, regress in the absenceoftestosteroneand antimüllerian hormone. Gartner ductcysts (GDCs) are rare remnantsofregressedwolffianducts.Theyareusuallysmall(<2cm)andlocatedwithintheanterolateral aspectoftheuppervagina.
CTimageswithreformatsdemonstratetheGartnerductcyst(arrow).