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Acknowledgements
We are grateful to the numerous congenital cardiac specialists who have
authored the chapters in this book. The expert knowledge that they have
imparted has made this a truly comprehensive text.
We would also like to thank Nicki Averill and Nicola Viola for providing
the majority of the illustrations used in the book. As regards the individual
chapters, we are appreciative of the numerous medical and surgical
colleagues, whom we have acknowledged in the appropriate chapters, for
providing some of the images and photographs. These are as follows:
Diane E. Spicer, Heart Institute, Johns Hopkins All Children’s
•
Hospital;
Professor Robert H. Anderson, Biosciences Institute, Newcastle
•
x
University;
Mr. Nicola Viola, Dr. Tara Bharucha, Dr. Trevor Richens, Dr. Andrew
•
Ho, Mr. Antonio Ravaglioli, Dr. James Shambrook, Dr. Shankar
Sadagopan, Dr. Charles Peebles, Dr. Kevin Roman, Dr. Lindsay
Smith, Mr. Pietro Malvindi and Mr. Theo Velissaris — all from
University Hospital Southampton;
Dr. Dhaval Parekh, Texas Children’s Hospital;
•
Professor Gurleen Sharland, Evelina London Children’s Hospital;
•
Dr. Will Regan, Evelina London Children’s Hospital;
•
Dr. Soha Romeih, Aswan Heart Centre, Egypt;
•
Dr. Fahad Alhabshan and Ms. Norah Al-Otaibi, National Guard
•
Health Affairs, Riyadh, Saudi Arabia;
Dr. Francisco Gonzales-Bartalay, Bristol Royal Hospital for Children;
•
Dr. Simon Bamforth, Newcastle University;
•
Professor Antoon F. M. Moorman and Dr. Aleksander Sizarov,
•
Academic Medical Center, Amsterdam;
Dr. Tom Semple, Royal Brompton Hospital, London;
•
Professor John Lamberti, Lucile Packard Children’s Hospital
•
Stanford, Palo Alto, California;
Gemma Price, Gemma Price Designs, Cobham, Surrey;
•
Professor Anthony Hlavacek, Medical University of South Carolina.
•
Acknowledgements
We are also grateful to the following for granting permission to reprint
copyrighted images:
Abbott;
•
Berlin Heart Inc.;
•
BioIntegral Surgical;
•
Cambridge Unversity Press;
•
Edwards Lifesciences Corporation;
•
Elsevier;
•
Getinge;
•
Mayo Foundation for Medical Education and Research;
•
Medtronic;
•
Springer;
•
St. Jude Medical;
•
Steinkopff Verlag;
•
Texas Children’s Hospital;
•
Wessex Heartbeat 3D Heart Library.
•
In addition, we would like to thank Mr. Nick Small, Cardiac Physiology
Unit, University Hospital Southampton NHS Foundation Trust, Professor
Subhasis Chakraborty, Children’s Hospital, Oxford University Hospital
NHS Trust and Mr. Nicola Viola, University Hospital Southampton NHS
Foundation Trust, for providing the images and photograph on the front
cover.
xi
Finally, we are deeply indebted to Nikki Bramhill from tfm publishing for
her expert production of this congenital cardiac surgical text and ongoing
enthusiasm for the ‘Key Question’ series of textbooks.
Contributors
Abdullah A. Alghamdi, MD MSc FRCSC
Head, Cardiac Surgery
Assistant Professor of Surgery
King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi
Arabia
David R. Anderson, MA MB BChir FRCS FRCS Edinb
Professor of Congenital Cardiac Surgery
King’s College London, UK
Consultant Cardiac Surgeon
Evelina London Children’s Hospital, Guy’s & St Thomas’ NHS
Foundation Trust, London, UK
Robert H. Anderson, BSc MD PhD (Hon) FRCPath FRCS Ed (Hon)
xii
Visiting Professorial Fellow
Biosciences Institute, Newcastle University, Newcastle-upon-Tyne, UK
Hiroko Asakai, MD
Research Fellow
The Royal Children’s Hospital, Parkville, Melbourne, Australia
Conal B. Austin, FRCS
Congenital Cardiac Surgeon
St Thomas’ Hospital, London, UK
Carles Bautista, MD MSc PhD
Paediatric Cardiology Consultant, Interventional Cardiology
The Royal Brompton Hospital, part of Guy’s and St Thomas’ NHS
Foundation Trust, London, UK
Lale Begum, BSc MSc PgDip
Lead Clinical Perfusion Scientist
Royal Brompton Hospital, London, UK
Tara Bharucha, MA (Cantab) MBBChir FRCP FESC
Consultant Paediatric and Fetal Cardiologist
Congenital Cardiac Centre, University Hospital Southampton,
Southampton, UK
Contributors
Mark S. Bleiweis, MD
Professor of Surgery and Pediatrics, University of Florida
Congenital Heart Center, Division of Cardiovascular Surgery,
Departments of Surgery and Pediatrics,
University of Florida, Gainesville, Florida, USA
William J. Brawn, CBE FRCS
Honorary Consultant in Congenital Heart Surgery
Birmingham Women’s and Children’s NHS Trust, Birmingham, UK
Harold M. Burkhart, MD
Professor and Chief, Division of Cardiac, Thoracic & Vascular Surgery
University of Oklahoma, Oklahoma, USA
Christopher A. Caldarone, MD
Donovan Chair, Professor, and Chief of Congenital Heart Surgery
Texas Children’s Hospital and Baylor College of Medicine, Houston,
Texas, USA
Sian Chivers, MBChB MRCPCH
Paediatric Cardiology Registrar
The Royal Brompton Hospital, part of Guy’s and St Thomas’ NHS
Foundation Trust, London, UK
Melanie A. Connett, BN (Hons) MSc
Paediatic Intensive Care Advanced Nurse Practitioner
Southampton Children’s Hospital, Southampton, UK
Miriam Conway, MBBS BSc (Hons) MRCP
Specialist Registrar in Cardiology
Royal Brompton Hospital, London, UK
Antonio F. Corno, MD FRCS FACC FETCS
Professor of Research in Pediatric and Congenital Heart Surgery
University of Texas Health, Houston, Texas, USA
Jennifer Co-Vu, MD
Attending Pediatric Cardiologist
Congenital Heart Center, Division of Pediatric Cardiology,
Department of Pediatrics,
University of Florida, Gainesville, Florida, USA
xiii
xiv
Key Questions in CONGENITAL CARDIAC SURGERY
Adrian Crucean, MD MS PhD
Consultant in Cardiac Morphology
Specialty Doctor in Congenital Heart Surgery
Birmingham Women’s and Children’s Hospital NHS Foundation Trust,
Birmingham, UK
Barbara J. Deal, MD MSc
Professor Emerita of Pediatrics
Northwestern University Feinberg School of Medicine, Chicago, Illinois,
USA
Joseph A. Dearani, MD
Professor of Surgery
Mayo Clinic, Rochester, Minnesota, USA
Eric Devaney, MD
Chief, Pediatric Cardiac Surgery
University Hospitals Rainbow Babies & Childrens Hospital, Cleveland,
Ohio, USA
Nigel E. Drury, BM (Hons) PhD FRCS (CTh)
Hunterian Professor & Consultant in Paediatric Cardiac Surgery
Birmingham Children’s Hospital, Birmingham, UK
Saravanan Durairaj, MBBS DCH MRCPCH
Consultant Paediatric Cardiologist
East Midland Congenital Heart Centre, University Hospitals of Leicester
NHS Trust, Leicester, UK
Pirooz Eghtesady, MD PhD
Professor of Surgery and Chief of Pediatric Cardiothoracic Surgery
St. Louis Children’s Hospital/Washington University in St. Louis, St. Louis,
Missouri, USA
Shakil Farid, MBBS FCPS MRCS Ed FRCS (CTh) MBA
Consultant Cardiac and Aortic Surgeon
Royal Papworth Hospital, Cambridge, UK
Charles D. Fraser, Jr., MD
Professor of Surgery and Perioperative Care, and Pediatrics
Chief, Pediatric and Congenital Cardiothoracic Surgery
Director, Texas Center for Pediatric and Congenital Heart Disease
Dell Medical School at The University of Texas at Austin/Dell Children’s
Medical Center, Austin, Texas, USA
Contributors
Simone Ghiselli, MD
Research Fellow
ASST Niguarda, Milan, Italy
Jorge M. Giroud, MD
Retired Attending Pediatric Cardiologist
All Children’s Hospital, Saint Petersburg, Florida, USA
Sarah Goring, MSc LCCP
Clinical Perfusionist
Wythenshawe Hospital, Manchester, UK
Michael J. Griksaitis, MBBS(Hons) MSc MRCPCH FFICM
Consultant Paediatric Intensivist & Honorary Senior Clinical Lecturer
Southampton Children’s Hospital, Southampton, UK
Faculty of Medicine, University of Southampton, UK
Kimberly A. Holst, MD
Chief Cardiothoracic Surgery Resident
Mayo Clinic, Rochester, Minnesota, USA
xv
Osami Honjo, MD PhD
Cardiovascular Surgeon, Associate Professor
The Hospital for Sick Children, University of Toronto, Toronto, Canada
Hatem Hosny, FRCS (CTh) FEBCTS (Cardiac) FEBCTS (Congenital)
Consultant Cardiac Surgeon
Aswan Heart Centre, Magdi Yacoub Foundation, Aswan, Egypt
Golnaz Houshmand, MD FSCMR
Cardiac Imaging Fellow
Royal Brompton Hospital, UK
Cardiology Consultant
Rajaie Cardiavascular, Medical and Research Center, Iran Unversity of
Medical Science, Tehran, Iran
Jeffrey P. Jacobs, MD FACS FACC FCCP
Professor of Surgery and Pediatrics, University of Florida
Congenital Heart Center, Division of Cardiovascular Surgery,
Departments of Surgery and Pediatrics,
University of Florida, Gainesville, Florida, USA
Sian Jaggar, MBBS BSc FRCA FFPMRCA CertMedEd MD
Consultant in Anaesthesia & Critical Care
Royal Brompton Hospital, London, UK
Key Questions in CONGENITAL CARDIAC SURGERY
Robert D. B. Jaquiss, MD
Chief of Pediatric and Congenital Heart Surgery
Pogue Distinguished Chair in Pediatric Cardiac Surgery Research
Professor of Thoracic and Cardiovascular Surgery and Pediatrics
Children’s Medical Center/UT Southwestern Medical Center
Dallas, Texas, USA
Natasha E. Khan, FRCS (CTh)
Consultant Cardiac Surgeon
Birmingham Children’s Hospital, Birmingham, UK
Ergin Kocyildirim, MD
Pediatric Cardiothoracic Surgeon
Assistant Professor
University of Pittsburgh, Pennsylvania, USA
Department of Cardiothoracic Surgery, Children’s Hospital of Pittsburgh,
McGowan Institute of Regenerative Medicine, Pittsburgh, Pennsylvania,
USA
xvi
Igor E. Konstantinov, MD PhD FRACS
Professor, Department of Paediatrics
University of Melbourne, Australia
Senior Research Fellow
Heart Research, Murdoch Children’s Research Institute, Melbourne, Australia
Director, Melbourne Centre for Cardiovascular Genomics and
Regenerative Medicine, Melbourne, Australia
Consultant Cardiothoracic Surgeon
The Royal Children’s Hospital, Parkville, Melbourne, Australia
Timothy S. Lancaster, MD MS
Fellow in Congenital Cardiac Surgery
Mott Children’s Hospital/University of Michigan, Ann Arbor, Michigan, USA
Michael Lavrsen, MD
Consultant Paediatric & Adult Congenital Cardiac Surgeon
University Hospital Southampton, Southampton, UK
Andrew J. Lodge, MD
Associate Professor of Surgery and Pediatrics
Duke University Health System, Durham, North Carolina, USA
Spiros Loggos, MD MSc
Senior Congenital Cardiac Fellow
Alder Hey Children’s Hospital, Liverpool, UK
Contributors
Attilio A. Lotto, MD MCh FRCS (CTh)
Consultant and Professor in Congenital Cardiac Surgery
Alder Hey Children’s and Liverpool Heart and Chest Hospital
Liverpool John Moores University, Liverpool, UK
Stefano M. Marianeschi, MD
Consultant Congenital Surgeon
ASST Niguarda, Milan, Italy
Christopher E. Mascio, MD
Professor and Chief, Division of Pediatric Cardiothoracic Surgery
Executive Director
WVU Medicine Children’s Heart Center
West Virginia University, West Virginia, USA
Constantine Mavroudis, MD
Chief of Pediatric Cardiothoracic Surgery
Peyton Manning Children’s Hospital, Indianapolis, Indiana, USA
Professor Emeritus of Surgery
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
xvii
Carlos M. Mery, MD MPH
Surgical Director, Coronary Anomalies Program
Associate Chief, Pediatric and Congenital Cardiothoracic Surgery
Associate Professor, Surgery and Perioperative Care, and Pediatrics
Texas Center for Pediatric and Congenital Heart Disease
Dell Medical School at The University of Texas at Austin/Dell Children’s
Medical Center, Austin, Texas, USA
Jacob R. Miller, MD
Instructor of Surgery
St. Louis Children’s Hospital/Washington University in St. Louis, St. Louis,
Missouri, USA
Branko Mimic, MD PhD
Consultant Congenital Cardiac Surgeon
University Hospitals of Leicester, Leicester, UK
Saeed Mirsadraee, MD MRCS FRCR FRCPE PhD
Consultant Radiologist
Royal Brompton and Harefield Hospitals, UK
xviii
Key Questions in CONGENITAL CARDIAC SURGERY
Narain Moorjani, MB ChB MRCS MD FRCS (CTh) MA
Consultant Cardiac Surgeon and Clinical Lead for Cardiac Surgery
Royal Papworth Hospital, Cambridge, UK
Associate Lecturer, University of Cambridge, UK
Victor O. Morell, MD
Eugene S. Weiner Endowed Professor and Chair of Pediatric
Cardiothoracic Surgery
Surgeon-in-Chief
Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
Executive Director
UPMC Heart and Vascular Institute, Pittsburgh, Pennsylvania, USA
Michael O. Murphy, MA MD MRCP FRCS
Congenital Cardiac Surgeon
Royal Brompton Hospital, London, UK
Raghav Murthy, MD DABS FACS FACC
Assistant Professor, Pediatric Cardiac Surgery
Mount Sinai Hospital, New York, USA
Shafi Mussa, MA MD FRCS (CTh)
Consultant Congenital Cardiac Surgeon
Bristol Royal Hospital for Children and Bristol Heart Institute, Bristol, UK
Phillip Naimo, BSc MD PhD
Research Fellow
The Royal Children’s Hospital, Parkville, Melbourne, Australia
Masakazu Nakao, MD FRCS (CTh)
Consultant Cardiac Surgeon
KK Women’s and Children’s Hospital, Singapore, Singapore
Nitha Naqvi, BSc (Hons) MBBS (Hons) MSc FRCPCH FRCP
Paediatric Cardiology Consultant with special interest in echocardiography
The Royal Brompton Hospital, part of Guy’s and St Thomas’ NHS
Foundation Trust, London, UK
Thieu Nguyen, MD
Attending Pediatric Cardiologist
Johns Hopkins All Children’s Hospital, Saint Petersburg, Florida, USA
Contributors
Giles J. Peek, MD
Professor of Surgery and Pediatrics, University of Florida
Congenital Heart Center, Division of Cardiovascular Surgery,
Departments of Surgery and Pediatrics,
University of Florida, Gainesville, Florida, USA
Susanna Price, MBBS BSc PhD FRCP EDICM FFICM FESC RCPathME
Consultant Cardiologist & Intensivist
Royal Brompton Hospital, London, UK
National Heart & Lung Institute, Imperial College, London, UK
Eric Y. Pruitt, MD
Cardiovascular Surgical Resident
Congenital Heart Center, Division of Cardiovascular Surgery,
Department of Surgery,
University of Florida, Gainesville, Florida, USA
Michael Puntis, MB BChir MA MRCS FRCA FFICM FHEA
Consultant Intensivist
St George’s University Hospitals NHS Foundation Trust, London, UK
xix
David N. Ranney, MD
Fellow in Cardiovascular and Thoracic Surgery
Duke University Medical Center, Durham, North Carolina, USA
Antonio Ravaglioli, MD
Congenital Cardiac Surgeon
University Hospital Southampton, Southampton, UK
Syed M. Rehman, MBBS BSc (Hons) MRCS FRCS (CTh)
Cardiothoracic Surgeon
Hammersmith Hospital, London, UK
Vanessa J. C. Rogers, BSc (Hons) MBBS MRCS FRCS (CTh)
Consultant Thoracic Surgeon
Queen Elizabeth Hospital, Birmingham, UK
Kelly Rosso, MD MS FACS
Consultant Breast Surgeon
Banner MD Anderson Cancer Center, Sun City West, Arizona, USA
Kasra Shaikhrezai, MD MSc MRCS FETCS MD (Res) FRCS (CTh)
Consultant Cardiac Surgeon
Golden Jubilee National Hospital, Glasgow, UK
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