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a
b
c
Fig. 1.4 The ASD cannot be seen in the standard view of TEE (0°) ( a ). With some rotation, the defect is visualized ( b ). The ASD/interatrial
septum (IAS) is 21/30 ( b ), and the posterior rim is 8 mm ( c ). LA left atrium, RA right atrium
ab
Fig. 1.5 TEE ( short-axis view ) shows that the ASD/IAS is 17/37 ( a ), the rim to the aorta is 9 mm, and the atrial depth is 38 mm ( b ) [ 1 ]. LA left
atrium, RA right atrium, AO aorta
Case 1 Atrial Septal Defect (ASD) Ostium Secundum Type
4
Diagnosis
The patient was symptomatic with an ASD (ostium secun­dum type). The maximum size of the ASD was 21 mm by TEE, and all the rims were greater than 5 mm.
Recommendation
Given the suitable rims and size of the ASD (ostium secun­dum type) and QP/QS of 2.5, the ASD device closure was recommended.
Lesson
1. Severe right ventricular dilation indicates that a left-to­right shunt in an ASD is signifi cant, especially in the absence of other causes of right ventricular dilation such as severe tricuspid regurgitation.
2. Qp/Qs >1.5 in an ASD (ostium secundum type) is an indi­cation for intervention [ 2 ].
3. For measuring the ASD rims to the neighboring vital organs, the posterior and anterior rims should be measured. The posterior-superior and the posterior-inferior rims are
the superior and inferior vena cava rims, respectively. The anterior-superior and the anterior- inferior rims are the rims to aorta and the tricuspid valve, respectively. The absence of rim to the aorta is not a contraindication for the ASD device closure [ 3 – 5 ].
4. What is the possible diagnosis of a dilated right ventricle?
4.1. ASD
4.2. Abnormal pulmonary venous return
4.3. Cor pulmonale and pulmonary thromboemboli
4.4. Severe tricuspid regurgitation
4.5. Pulmonary hypertension
4.6. Ebstein’s anomaly
4.7. Right ventricular dysplasia
4.8. Right ventricular dysfunction, e.g., due to right ven-
tricular infarction
5. In this patient, ASD was not visualized in classic 0° view, so measurement of the rim to mitral or tricuspid valve was not possible.
a
b
Fig. 1.6 TEE ( bicaval view ) shows that the ASD/IAS is 19/58 ( a ), the rim to the superior vena cava is 27 mm, and the rim to the inferior vena
cava is 14 mm ( b ). LA left atrium, RA right atrium
Case 1 Atrial Septal Defect (ASD) Ostium Secundum Type
5
H. Sadeghian, Z. Savand-Roomi, Echocardiographic Atlas of Adult Congenital Heart Disease, DOI 10.1007/978-3-319-12934-1_2, © Springer International Publishing Switzerland 2015
A 17-year-old male presented with dyspnea on exertion (functional class I) and a systolic murmur at the lower ster­nal border. Transthoracic echocardiography revealed an
atrial septal defect (ASD) (ostium secundum type) with the Qp/Qs of 2 and the systolic peak arterial pressure of 40 mmHg.
Atrial Septal Defect (Ostium Secundum Type) Attached to the Coronary Sinus
Case 2
Electronic supplementary material The online version of this chapter (doi:
10.1007/978-3-319-12934-1_2 ) contains supplementary material,
which is available to authorized users.
Fig. 2.1 The apical four-chamber view shows severe right atrial and
ventricular enlargement, an ASD (ostium secundum type) ( arrow ), and a prominent Eustachian valve ( curved arrow ). RA right atrium, LA left atrium, RV right ventricle, LV left ventricle
a b
Fig. 2.2 The ASD is attached to the coronary sinus ( arrow head ), and
there is no rim to the coronary sinus on transesophageal echocardiography (TEE) (0°) in the lower esophageal level ( arrow ) ( a ). This is a schematic
illustration of the ASD (ostium secundum type), which is attached to the coronary sinus on TEE (0°) ( b ). LA left atrium, RA right atrium, LV left ventricle, RV right ventricle, ASD atrial septal defect, CS coronary sinus
6
Diagnosis
There was an ASD (ostium secundum type) attached to the coronary sinus.
Comment
Given the patient’s Qp/Qs of 2, mildly elevated systolic pul­monary arterial pressure, and absence of rim to the coronary sinus, surgery was recommended.
Lesson
In case of an ASD (ostium secundum type), TEE (0°) in the lower esophageal level is used for the visualization of the coronary sinus. If the rim of the ASD to the coronary sinus is not enough, surgery is recommended [ 3 – 5 ]. The rim to the coronary sinus is not always measurable. Sometimes on TEE (0°) in the lower esophageal level, where the coronary sinus can be visualized, the ASD is not detectable.
Case 2 Atrial Septal Defect (Ostium Secundum Type) Attached to the Coronary Sinus
7
H. Sadeghian, Z. Savand-Roomi, Echocardiographic Atlas of Adult Congenital Heart Disease, DOI 10.1007/978-3-319-12934-1_3, © Springer International Publishing Switzerland 2015
A 30-year-old woman presented with recent dyspnea on exertion (functional class II). Physical examination revealed an ejection systolic murmur at the second left intercostal space and fi xed S2 splitting. Electrocardiography showed normal sinus rhythm, right axis deviation, and rsr’ in leads V1 and V2.
Atrial Septal Defect (Ostium Secundum Type) with a Small Rim to the Inferior Vena Cava
Case 3
Fig. 3.1 The parasternal long-axis view demonstrates right ventricular
dilation. LA left atrium, RV right ventricle, LV left ventricle, AO aorta
Electronic supplementary material The online version of this chapter (doi:
10.1007/978-3-319-12934-1_3 ) contains supplementary
material, which is available to authorized users.
8
ab
c
Fig. 3.3 Transesophageal echocardiography (TEE) (0°) demonstrates
that the ASD/interatrial septum (IAS) is 20/42 ( a ), the posterior rim is 11 mm, and the rim to the mitral valve is 14 mm ( b ). This is a schematic
illustration of the ASD (ostium secundum type) in this view ( c ). RA right atrium, RV right ventricle, LA left atrium, ASDOS atrial septal defect ostium secondum type
a b
Fig. 3.2 The apical four-chamber view demonstrates moderate right
ventricular dilation and the passage of the fl ow through the ASD (ostium secundum type) ( arrow ) ( a ) from the left atrium toward the
right atrium. This is a schematic illustration of the ASD (ostium secun­dum type) ( b ). RA right atrium, RV right ventricle, LA left atrium, LV left ventricle
Case 3 Atrial Septal Defect (Ostium Secundum Type) with a Small Rim to the Inferior Vena Cava
9
ab
d
c
Fig. 3.4 TEE ( short-axis view ) demonstrates that the ASD/IAS is
29/45 ( a ), the rim to the aorta is 8 mm and the opposite rim is 11mm ( b ), and the atrial depth is 30 mm ( c ). This is a schematic illustration of
the atrial depth and the rim to the aorta on TEE ( short-axis view ) ( d ). RA right atrium, RV right ventricle, LA left atrium, AO aorta
Case 3 Atrial Septal Defect (Ostium Secundum Type) with a Small Rim to the Inferior Vena Cava
10
Diagnosis
The patient was symptomatic and was diagnosed with an ASD (ostium secundum type) with moderate right ventricu­lar enlargement and inadequate rim to the inferior vena cava.
Recommendation
Given the patient’s relatively small rim to the inferior vena cava (5 mm), surgical ASD closure was recommended.
Lesson
It is important that the rims of an ASD (ostium secundum type) to the superior and inferior venae cavae, mitral and
tricuspid valves, and coronary sinus be measured before the ASD device closure. (These rims should be greater than 5 mm.) Moreover, the ASD should not be too large (stretched balloon diameter <38–41 mm), and it should have suitable anatomy [ 2 , 6 , 7 ].
Rims:
1. Posterosuperior rim: rim to the superior vena cava
2. Posteroinferior rim: rim to the inferior vena cava
3. Anterosuperior rim: rim to the aorta
4. Anteroinferior rim: rim to the tricuspid valve
5. Posterior rim on TEE (0°): rim to the right upper pulmo­nary vein [ 8 ]
a
c
b
Fig. 3.5 TEE ( bicaval view ) shows that the size of the ASD is 31 mm
( a ), the rim to the inferior vena cava is 5 mm, and the rim to the superior vena cava is 25 mm ( b ). A schematic illustration of the ASD (ostium
secundum type) and its rims is presented in this view ( c ). RA right atrium, LA left atrium, SVC superior vena cava, IVC inferior vena cava
Case 3 Atrial Septal Defect (Ostium Secundum Type) with a Small Rim to the Inferior Vena Cava
11
H. Sadeghian, Z. Savand-Roomi, Echocardiographic Atlas of Adult Congenital Heart Disease, DOI 10.1007/978-3-319-12934-1_4, © Springer International Publishing Switzerland 2015
A 26-year-old pregnant woman, who had undergone surgi­cal atrial septal defect (ASD) closure 2 years previously, referred to our clinic for checkup. This was her second pregnancy. During her fi rst pregnancy, she was diagnosed with an ASD (ostium secundum type) with pulmonary arte­rial hypertension. The fi rst transthoracic echocardiography and transesophageal echocardiography (TEE) demonstrated that the size of the ostium secundum ASD was 36 mm; the systolic and mean pulmonary arterial pressures were 110
and 55 mmHg, respectively; and the pulmonary and sys­temic vascular resistance was 7 and 20 units, respectively. The mean pulmonary arterial pressure reached to 45 mmHg with 10 minutes of oxygen, although it decreased up to 10 mmHg but mean pulmonary arterial pressure was still more than 40 mmHg. Therefore, she underwent termina­tion of her fi rst pregnancy before referral for cardiac surgery. Follow-up echocardiography after cardiac surgery revealed the following:
Atrial Septal Defect (Ostium Secundum Type) with Pulmonary Arterial Hypertension Subjected to Patch Closure with a Valve
Case 4
Fig. 4.2 TEE (90°) shows the ASD, which is 7 mm in size. LA left
atrium, RA right atrium
Fig. 4.1 An ASD (ostium secundum type) ( arrow ) can be seen on
transthoracic echocardiography (four-chamber view). RA right atrium, RV right ventricle, LV left ventricle
12
Comment
Because of the patient’s pulmonary arterial hypertension at the time of surgery, the surgeon performed ASD double patch closure with a check valve. Accordingly, only follow­ up was recommended for the patient. The fi rst postoperative transthoracic echocardiography revealed a pulmonary arte­rial pressure (PAP) of 60 mmHg.
Lesson
1. This ASD (ASD double patch closure with a check valve) should not be confused with a residual postoperative ASD.
2. Before operation, despite the patient’s elevated pulmo­nary vascular resistance (7 unit), the left-to-right shunt was still more than 1.5, and the pulmonary arterial sys­tolic pressure was still subsystemic. The systolic pulmo-
nary artery pressure was 110 mmHg by catheterism, the pulmonary arterial diastolic pressure was 40 mmHg, and the aortic systolic pressure was 140 mmHg. Although the ratio of pulmonary vascular resistance to systemic vascular resistance was 7/20 (is equal to 0.35 < 2/3) and the ratio of systolic pulmonary arterial pressure to sys­temic was 0.78 (more than 2/3), the left-to-right shunt was more than 1.5 (1.85), so closure of atrial septal defect seemed logic [ 2 , 7 , 9 ]. Use of fenestrated ASD occluder has also been reported for ASD with pulmo­nary arterial hypertension [ 10 , 11 ]. In another study, ASD occluder used with ASD and pulmonary vascular resistance more than six units, if during 1 h of occlusion mean pulmonary arterial pressure falls 20 %, no fall in systemic pressure and no worsening of sign or symptom occur [ 9 ].
Case 4 Atrial Septal Defect (Ostium Secundum Type) with Pulmonary Arterial Hypertension Subjected to Patch Closure with a Valve