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Fig. 41.11 Preoperative image of post-nasal space with a tumour involving lateral wall (top), Medial and lateral pterygoids have been exposed, posterior wall off maxillary sinus overlying contents of PPF was removed (middle), Lateral and medial pterygoids together with Eustachian tube cartilage were removed leaving exposed lateral and medial pterygoid muscle and parapharyngeal space
P. Surda et al.
Posterior maxillary sinus wall is removed drilled down completely. Once this is achieved, the next step is to mobilise the contents of PPF by dividing the greater palatine artery, vidian bundle and SPA. PPF is pushed laterally in order to drill away medial and lateral pterygoid plates. This gives us access to paraharyngeal space and infratemporal fossa. Tumours extending into this area often invade Eustachian tube and cartilage. In such cases, this must be transected and removed together with peritubaric muscles and partially with both pterygoid muscles.
Prior to further dissection, it is mandatory to identify ICA.Dissection of the vidian canal tracks posteriorly towards
the second genu of the ICA.As we drill the oor of the sphenoid sinus, Vidian canal is identied at the junction of the medial pterygoid plate and the lateral sphenoid oor. Using diamond burr, Vidian canal then is gently drilled away with until we establish the exact position of ICA, which can be followed to further identify the horizontal portion entering petrous apex.
Subsequently, Eustachian tube and surrounding muscles can be removed. Area is reconstructed with nasoseptal ap. We recommend placing multiple pieces of nasopore over the nasoseptal ap. Reconstructed area is supported with silastic sheet, which is attached to the nasal septum and removed 5weeks after the surgery.
SPA a. &
41 Endoscopic Resection ofNasal andParanasal Sinus Neoplasms
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MT
foramen
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Middle cranial
R
LRS
V
fossa
Petrous ICA
Fig. 41.12 Illustration of anatomical areas that can be accessed via posterior maxillary wall using the approach described by Kesimsiri et al. [29]. MT middle turbinate; PNS postnasal space; LRS lateral
41.7 Treatment oftheNeck
Management of the neck in primary sinonasal neoplasms is a topic that continues to provoke signicant debate. There is a ne balance to be struck between optimising oncologic out­comes and limiting the morbidity associated with treatment of the neck.
One key principle is that all patients with conrmed sino­nasal neoplasm must have clinical assessment of the neck through careful palpation of all cervical nodal levels. Detection of a nodal mass should prompt further evaluation, most often by ultrasound guided ne needle cytology. In addition, the vast majority of patients with sinonasal neo­plasms will have imaging scans that stage the neck and chest. The workhorse of neck staging scans is the CT, as it offers excellent sift tissue resolution of nodal groups including the retropharyngeal lymphatics, which are the rst echelon for the maxillary sinus and nasal oor. Pathological nodes detected at imaging will be reected in staging, with conse­quences for both curability and treatment intensity.
A patient with no pathological nodes found at clinical and radiological evaluation is said to have a ‘N0’ neck. The most contentious debate is centred around these patients and
PPF
Maxillary
sinus
PNS
recess of sphenoid sinus; PPF pterygopalatine fossa; ITF infratemporal fossa; ICA internal carotid artery; SPA sphenopalatine artery
ITF
the need for elective treatment of the N0 neck. One broad principle of management of neck metastases comes from the British Association of Head and Neck Oncologists, who would advocate elective neck treatment if the risk of metas­tases is greater than 10–15%. The overall risk of neck metastases in sinonasal malignancies is 25%; however, there is wide variation according to histological subtype. Therefore, the rationale for elective treatment of the neck is strongest in esthesioneuroblastoma and weakest in adeno­carcinoma [28].
In addition, as tumour stage progresses there is an increased rate of nodal metastases. Patients with T3 and 4 squamous cell carcinomas and SNUC are therefore likely to have a risk of nodal involvement of 15% or greater and thus are considered for elective neck treatment [23, 28].
Individual MDTs will have individual preferences for the strategy to treat both N0 and N+ neck disease, whether surgi­cal or with radiotherapy. Both have proponents and detrac­tors, and neither is without morbidity; a case can be made for either surgical or oncological treatment on an individual basis. However, as far as possible, a single strategy should be used to treat the neck to minimise morbidity and preserve a treatment option for future in the case of recurrence.
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References
1. Lund VJ, Clarke PM, Swift AC, McGarry GW, Kerawala C, Carnell D. Nose and paranasal sinus tumours: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol. 2016;130(S2):S111–8.
2. Peck BW, Van Abel KM, Moore EJ, Price DL.Rates and locations of regional metastases in sinonasal malignancies: the mayo clinic experience. J Neurol Surg B Skull Base. 2018;79(3):282–8.
3. Floreani SR, Nair SB, Switajewski MC, Wormald PJ. Endoscopic anterior ethmoidal artery ligation: a cadaver study. Laryngoscope. 2006;116(7):1263–7.
4. Solari D, Chiaramonte C, Di Somma A, etal. Endoscopic anatomy of the skull base explored through the nose. World Neurosurg. 2014;82(6 Suppl):S164–70.
5. Bhattacharyya N. Cancer of the nasal cavity. Arch Otolaryngol Head Neck Surg. 2002;128(9):1079.
6. Binazzi A, Corati M, Di Marzio D, etal. Sinonasal cancer in the Italian national surveillance system: epidemiology, occupation, and public health implications. Am J Ind Med. 2017;61(3):239–50.
7. Cantu G, Solero CL, Mariani L, etal. Intestinal type adenocarci­noma of the ethmoid sinus in wood and leather workers: a retro­spective study of 153 cases. Head Neck. 2011;33(4):535–42.
8. Leivo I. Intestinal-type adenocarcinoma: classication, immu­nophenotype, molecular features and differential diagnosis. Head Neck Pathol. 2017;11(3):295–300.
9. Ow TJ, Hanna EY, Roberts DB, et al. Optimization of long-term outcomes for patients with esthesioneuroblastoma. Head Neck. 2013;36(4):524–30.
10. Morita A, Ebersold MJ, Olsen KD, Foote RL, Lewis JE, Quast LM.Esthesioneuroblastoma. Neurosurgery. 1993;32(5):706–15.
11. Spiro JD, Soo KC, Spiro RH. Nonsquamous cell malignant neo­plasms of the nasal cavities and paranasal sinuses. Head Neck. 1995;17(2):114–8.
12. Su SY, Kupferman ME, DeMonte F, Levine NB, Raza SM, Hanna EY.Endoscopic resection of Sinonasal cancers. Curr Onecol Rep. 2014;16(2).
13. Lupinetti AD, Roberts DB, Williams MD, etal. Sinonasal adenoid cystic carcinoma. Cancer. 2007;110(12):2726–31.
14. Bhattacharyya N.Symptom outcomes after endoscopic sinus sur­gery for chronic rhinosinusitis. Arch Otolaryngol Head Neck Surg. 2004;130(3):329.
15. de Almeida JR, Su SY, Koutourousiou M, etal. Endonasal endo­scopic surgery for squamous cell carcinoma of the sinonasal cavi­ties and skull base: oncologic outcomes based on treatment strategy and tumor etiology. Head Neck. 2014;37(8):1163–9.
16. Nicolai P, Schreiber A, Bolzoni Villaret A, et al. Intestinal type adenocarcinoma of the ethmoid: outcomes of a treatment regimen based on endoscopic surgery with or without radiotherapy. Head Neck. 2015;38(S1):E996–E1003.
17. Antognoni P, Turri-Zanoni M, Gottardo S, etal. Endoscopic resec­tion followed by adjuvant radiotherapy for sinonasal intestinal-type adenocarcinoma: retrospective analysis of 30 consecutive patients. Head Neck. 2014;37(5):677–84.
18. Bhayani MK, Yilmaz T, Sweeney A, et al. Sinonasal adenocar­cinoma: a 16-year experience at a single institution. Head Neck. 2014;36(10):1490–6.
19. Castelnuovo P, Bignami M, Delù G, Battaglia P, Bignardi M, Dallan I. Endonasal endoscopic resection and radiotherapy in olfactory neuroblastoma: our experience. Head Neck. 2007;29(9):845–50.
20. Devaiah AK, Andreoli MT. Treatment of esthesioneuroblas­toma: a 16-year meta-analysis of 361 patients. Laryngoscope. 2009;119(7):1412–6.
21. Dulguerov P, Allal AS, Calcaterra TC.Esthesioneuroblastoma: a meta-analysis and review. Lancet Oncol. 2001;2(11):683–90.
22. Nishimura H, Ogino T, Kawashima M, et al. Proton-beam ther­apy for olfactory neuroblastoma. Int J Radiat Oncol Biol Phys. 2007;68(3):758–62.
23. Faisal M, Seemann R, Lill C, etal. Elective neck treatment in sino­nasal undifferentiated carcinoma: systematic review and meta-anal­ysis. Head Neck. 2020;42(5):1057–66.
24. Lund Valerie J.Sinonasal Malignant Melanoma. Advances in oto­rhino-laryngology. S.Karger AG; 2020. p.185–96.
25. Castelnuovo P, Turri-Zanoni M, Battaglia P, Antognoni P, Bossi P, Locatelli D. Sinonasal malignancies of anterior skull base: histology-driven treatment strategies. Otolaryngol Clin N Am. 2016;49(1):183–200.
26. Turri-Zanoni M, Lambertoni A, Margherini S, Giovannardi M, Ferrari M.Multidisciplinary treatment algorithm for the manage­ment of sinonasal cancers with orbital invasion: a retrospective study. Head Nick. 2019;41(8):2777–88.
27. Amin N, Jacques T, Ting F, Hopkins C, Surda P.Protective Silastic® sheet in combined transorbital and transnasal resection of sinonasal lesions. Rhinol Online. 2018;1(1):127–32.
28. Dooley L, Shah J.Management of the neck in maxillary sinus carci­nomas. Curr Opin Otolaryngol Head Neck Surg. 2015;23(2):107–14.
29. Kasemsiri P, Solares CA, Carrau RL, Prosser JD, Prevedello DM, Otto BA, et al. Endoscopic endonasal transpterygoid approaches: anatomical landmarks for planning the surgical cor­ridor. Laryngoscope. 2013;123(4):811–5. https://doi.org/10.1002/
lary.23697.
Maxillectomy
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42.1 Introduction
A maxillectomy is dened as an operation that involves removal of all or part of the maxillary bone. The broad indi­cation for a maxillectomy is to resect pathology originating from, or invading the maxilla. It may not be surprising to know that the surgical principles discussed in this chapter have not changed a great deal over the past few decades—the main advancement being the advent of endoscopic surgery and improved three-dimensional planning to facilitate more accurate reconstruction.
It is outside the scope of this atlas to provide a full ana­tomical review, but readers should be aware of the key struc­tures that can cause potential complications, both intra- and post-operatively. The maxilla houses the maxillary antrum with its role in sinus drainage, as well as supporting the orbit, attaching laterally to the zygoma, dening the nasal cavity medially and forming the roof of the mouth inferiorly con­taining the upper dental arch. The maxillary antrum is one of four bilateral sets of paranasal sinuses, in close relationship to the frontal, sphenoid and ethmoid sinuses. Despite its role in middle third anterior facial prominence, the maxilla extends both superiorly and posteriorly into areas of high anatomical risk. Posterosuperiorly lies the base of skull, with
K. Payne Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
O. Breik (*) Department of Oral and Maxillofacial Surgery, Royal Brisbane and Women’s Hospital, University of Queensland, Brisbane, QLD, Australia
P. Praveen Department of Oral and Maxillofacial Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK e-mail: prav.praveen@uhb.nhs.uk
S. Parmar Department of Oral and Maxillofacial/Head and Neck Surgery, Queen Elizabeth Hospital, Birmingham, UK
the anterior two thirds of the orbital oor being thin maxil­lary bone. The arterial supply of the maxilla originates from the maxillary artery, a branch of the external carotid artery. Branches of the third part of the maxillary artery (in relation to the lateral pterygoid muscles) supply the midface, includ­ing the—posterior superior alveolar artery, infraorbital artery, descending palatine artery and sphenopalatine artery. On the whole, venous draining mirrors the arterial supply; however, of clinical relevance is the pterygoid venous plexus located in the infratemporal fossa posterior to the maxilla. The pterygoid venous plexus is a potential source of consid­erable intra-operative bleeding when dissecting and osteoto­mising the posterior maxilla. This chapter will discuss the preoperative assessment and surgical planning of a maxil­lectomy patient, further detailing the classication, surgical approaches and maxillectomy procedure itself with the aid of intra-operative clinical photographs.
42.2 Preoperative Checklist, Considerations andAnaesthesia
42.2.1 Preoperative Investigations
Routine investigations should be as per the preoperative work-up for any major head and neck surgical procedure. These include blood tests (full blood count, renal function, clotting screen, cross-match/group and save), electrocardio­gram, CXR and exercise tolerance testing if indicated.
Special investigations will have been performed to stage the tumour. Our protocol is for a CT head, neck and thorax, to include an MRI head if marrow signal from bony inltra­tion, but other institutional imaging protocols may vary and should be followed accordingly. Cross-sectional imaging will demonstrate the extent of the tumour and guide the plan for resection. Depending on the extent of the tumour, the sur­geon can begin to plan the ideal approach to resecting the maxilla. Patients planned for larger resections including the
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orbital oor should have preoperative ophthalmic assess­ment, to include visual acuity and a HESS chart.
Hints and Tips
3D surgical planning will require a ‘ne-cut’ CT scan of the facial skeleton and the planned graft site. The data from this scan will enable software to render and manipulate the defect and an accurate stereolitho­graphic 3D model to be printed and/or virtual plan­ning. If these facilities are available in your institution, always be sure to arrange for this scan early to give adequate time for reconstructive planning.
42.2.2 Reconstructive Considerations
Whilst the primary goal of all surgical oncology is resection of the tumour mass with adequate margins, it is prudent for the head and neck surgeon to consider reconstruction and functional rehabilitation from the outset when considering resection of the facial skeleton. This is particularly important when the tumour affects the maxilla/midface, as any recon­struction will have a potential impact upon mastication, speech, swallow, vision and appearance. Options include early or immediate reconstruct on with local or microvascu­lar free aps, with or without osseointegrated dental implants or an obturator- based prosthesis. Obturators may be the ideal option for small maxillectomy defects and where retention is possible from residual teeth. Reconstruction has advantages over obturation—providing better outcomes for swallowing and speech, especially in larger defects and when a signi­cant amount of soft palate has also been removed. However, patient and surgical factors may impact this decision, and the best practice is to consider these preoperatively and to have open discussions of risk and morbidity with the patient. Negating the additional operating time and surgical morbid­ity associated with free-tissue reconstruction may be favour­able to reduce general anaesthetic time in high-risk patients.
Small alveolar defects can be closed with a buccal fat pad or mucosal advancement ap and palatal defects with a muco­sal island ap. Larger defects can be closed with a temporalis ap but more often will require a soft tissue free-ap, most commonly a radial forearm ap. When signicant bone has been removed, in a Brown class II, III or IV defect, osseous or composite osseo-cutaneous or myo-osseous free-aps should be considered, options include the bula, DCIA or scapular free-ap, among others [1]. This would provide bony support for dental implants in large horizontal defects, or providing support for orbital oor reconstruction in large vertical defects and in turn preserve facial symmetry and contour. For poste­rior defects only, an alternative option is to consider a soft tis­sue ap with immediate implants. A ‘zygomatic implant perforator’ (ZIP) ap involves placing immediate zygomatic
implants perforating through a soft tissue ap (usually a radial forearm) to support early dental rehabilitation without the need for a bony free ap reconstruction [2].
Where possible, virtual planning can be utilised to plan the resection and reconstruction. With the development of 3D printing technology, cutting guides can be designed and printed for an accurate resection and accurate reconstruction. Figure42.1 demonstrates a case where resection is planned, with preparation of cutting guides, as well as cutting guides for harvest of a deep circumex iliac artery (DCIA) free-ap reconstruction of the left maxilla (Fig.42.1).
42.2.3 Anaesthesia andAirway
The patient will be under a general anaesthesia, and the main point to highlight here is the method of securing the airway. Preference will depend on the surgeon and anaesthetist. For smaller resection with a limited approach, a nasal or oral tube is reasonable. As will be discussed, more often than not the maxil­lectomy will be part of a larger procedure involving regional lymph node clearance in the form of a neck dissection with/ without reconstruction. In this instance, a tracheostomy pro­vides a secure airway with adequate intra-oral and neck access.
42.2.4 Consent
Consenting for a maxillectomy will undoubtedly be one stage of a larger procedure. Whilst there may be overlap of risks between these stages, the specic risks of the maxil­lectomy resection need to be considered. Obviously, these will change depending on the approach and extent of the maxillectomy procedure undertaken.
General risks include bleeding, swelling, bruising, infec­tion and scarring.
Specic Risks
• Scarring/tethering of upper lip
• Nasal deviation/deformity
• Skin breakdown
• Numbness of cheek
• Epiphora
• Scarring of lower eyelid and ectropion
• Trismus
• Tracheostomy (if not planned and consented for
separately)
• Dental extraction required as necessary
• Vessel/nerve damage (specic to approach and type of
maxillectomy)
• Complications involving eye if resecting orbital oor or
close to orbit—diplopia, ocular dysmotility, change in
vision, retrobulbar bleed resulting in permanent visual loss
• Trismus and altered mastication/dental function
• Tumour unresectable
ab
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c
d
e
Fig. 42.1 Virtual surgical planning. (a) Planned resection of left max- illa. (b) Cutting guides prepared to allow accurate resection. (c) Planned area of iliac crest for harvest where the curve of the iliac crest best
represents the shape and curvature of the left maxilla. (d, e) Iliac crest superimposed on the defect, showing excellent curvature and contour of the iliac crest for left maxillary reconstruction
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42.3 Indications
42.3.1 Pathology
As discussed, a maxillectomy is a procedure to resect abnor­mal pathology of the maxilla or invading the maxilla. Malignancy will be the indication in the majority of cases, most commonly, an epithelial cancer of the oral cavity (upper alveolus) that has invaded the maxillary bone or requires bone resection to obtain a clear margin. Of this group, a squamous cell carcinoma (SCC) is by far the most prevalent, and primary SCC of the maxillary sinus is much less com­mon (<3% of head and neck cancers). Other rarer histologi­cal subtypes include salivary cancer—adenoid cystic or mucoepidermoid carcinoma and sarcoma or lymphoma. On occasion, it may be necessary to perform a maxillectomy for benign pathology, for example, brous dysplasia, an inltrat­ing bro-inammatory lesion, or extensive osteonecrosis.
42.3.2 Contraindications
Contraindications for a maxillectomy can be divided into patient-specic and disease-specic factors. Patient factors will be identied in preoperative assessment, including (among others) systemic disorders such as severely uncon­trolled diabetes, untreated coagulopathy, poor cardiorespira­tory reserve with high mortality risk from general anaesthesia or a prolonged procedure. Disease contraindications will be identied when staging the pathology and will indicate an inoperable malignancy due to extend of invasion, for exam­ple, signicant skull base extension. These factors will often be case/patient specic and should always be discussed at the head and neck cancer multidisciplinary team meeting.
42.3.3 Maxillectomy Classication
There is a plethora of published classications for maxillary defects in the literature, and confusion arises when literature uses terminology from different classications interchange­ably. The classication system proposed by Cordeiro (2000) [3] uses the terms ‘limited’, ‘sub-total maxillectomy’ and ‘total maxillectomy’, somewhat analogous to a Brown class I-III. In general, a sub-total maxillectomy preserves the orbital oor and contents, a total maxillectomy resects the orbital oor and an orbito-maxillectomy resects the orbital contents (Brown class IV). A ‘partial maxillectomy’ (Davison classication, 1998 [4]) is analogous to a sub-total maxil­lectomy; however, the terms ‘infrastructure’ and ‘suprastruc­ture’ maxillectomy can be confusing. An infrastructure maxillectomy corresponds to a Brown class I/II, whilst a suprastructure maxillectomy is nearer to a Brown class V defect. A ‘medial’ maxillectomy describes resection of the medial and supero-medial walls of the maxilla, often accessed via endoscopic means or a lateral rhinotomy incision.
In this chapter we refer to the Brown classication of maxillary defects. Originally published in 2000, the Brown classication described maxillectomy defects as a combina­tion of four vertical components (I–IV) and three horizontal components (a–c). In general, the vertical component describes the likely aesthetic effect of surgery and the hori­zontal component the difculty of oral rehabilitation. In 2010, Brown (Fig.42.2) revised the classication to include vertical midface components—orbitomaxillary (V) and nasomaxillary (VI) [5].
III
Fig. 42.2 Brown classication of maxillectomy defects, with Class I–IV representing vertical resection components, and a–d representing hori­zontal components [5]
III IV
I
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42.4 Surgical Technique
As highlighted, a maxillectomy is not one single procedure, but a collection of variants based upon a core procedure to deal with the complex anatomy and difcult surgical access in this area. As such, no one approach can be applied to all resections. One should be aware of the different approaches and types of maxillectomy and the common combinations of these. Such knowledge is paramount, in addition to the exibility to change approach on table should the resection or potential complications require it. Surgical approaches to the maxilla include: transoral, transnasal, lateral rhinotomy, transfacial (Weber-Fergusson), midfacial degloving, transmandibular and bicoronal/cranial (for retromaxillary access). All of these approaches are done under a general anaesthetic and local anaesthetic injection of lignocaine with adrenaline at planned incision sites. Corneal shields or temporary tarsorrhaphy inci­sions should be used to protect the cornea. This section will discuss the techniques for various surgical approaches avail­able to access the maxilla and highlight different types of max­illectomy procedures for different classications of defect.
42.4.1 Transoral Approach
Most small tumours of the maxillary alveolus or palate are easily accessible via a simple transoral approach. This tech­nique is commonly employed and is the technique of choice for most small anterior maxillary/palatal lesions, or Class I and low-level Class II resections in patients with adequate mouth opening. The main advantage of the transoral approach is that it leaves no facial scars. The approach involves mark­ing out the planned margins around the tumour/lesion. This is followed by a dissection down to bone. Once adequate bony exposure is achieved, a reciprocating saw is used to perform the osteotomies. The rst osteotomies should be the vertical osteotomies either through tooth sockets, or between teeth. Linking palatal and horizontal osteotomies can then be per­formed, and these are linked to the vertical osteotomies. Once completed, the lesion can be mobilised by using straight osteotomes. Often, with transoral resections, the main bleed­ing is encountered from the greater palatine artery. This can often be controlled with bipolar diathermy (Fig.42.3).
Hints and Tips
The limits of the transoral approach will often be reached when trying to achieve the posterior resection margin. A resection should never be compromised in efforts to preserve cosmesis. If there is concern about achieving an adequate resection margin, the authors have a low threshold for performing a lip split and lim­ited Weber Fergusson approach to improve access. This will be discussed further below.
42.4.2 Transnasal
The transnasal approach is an almost exclusive endoscopi­cally assisted approach to small tumours only of the maxil­lary sinus or maxillary septum. In experienced hands, it provides excellent access to the nasal cavity and also the associated paranasal sinuses and skull base. Small sinus and septal tumours extending into the oral cavity can also be resected via combined endoscopic and transoral approach. A nasal septal lesion involving the palate can be approached endoscopically to separate the septum above the lesion, fol­lowed by intraoral resection around the lesion allowing the lesion to be delivered through the oral cavity. With the devel­opment of improved endoscopic skills, total maxillectomies can potentially be performed using these combined tech­niques [6].
42.4.3 Lateral Rhinotomy
Arguably, this approach has been superseded by recent advances in endoscopic surgery. However, for large or difcult to access sinonasal masses of the lateral nasal wall, this is still the approach of choice. It also provides access to the ethmoid and frontal sinuses, anterior skull base and the nasopharynx. This approach has found its widest application in medial max­illectomies for inverted papilloma [7]. The main advantage of this access procedure is its versatility. If required, the incision can be extended superiorly with the addition of a lynch exten­sion or glabellar extension or inferiorly within the nasolabial fold, or a lip split. With a lip split and a lynch style incision for superior extension, orbital access can be improved, and even posterior maxillary access can be adequate for a total maxil­lectomy [8]. The traditional lateral rhinotomy approach begins with a skin incision below the columella in the midline, extending around the alar and into the supra-alar crease and superiorly into the facial nasal groove. The incision is carried through the muscular layer to the piriform aperture. Once in the subperiosteal plane, the piriform fossa is identied and fol­lowed superiorly to identify the nasal bones. Depending on the access required, the nasal lining is then incised through the lateral nasal vestibule to access the nasal cavity, being mindful to avoid hitting the inferior turbinate. For a complete medial maxillectomy, the medial canthal ligament is detached to access the medial wall of the orbit, and the nasolacrimal duct is transected at the junction with the nasolacrimal sac. The sac needs to be then divided and marsupialised to prevent develop­ment of epiphora. Using small osteotomes, osteotomies per­formed of the nasal process of the maxilla and nasofrontal junction then allows mobilisation of the nasal complex with the overlying soft tissue giving access to the ipsilateral nasal cavity. For access to entire nasal cavity, the septum is released from the mobilised segment. Lateral elevation of the cheek ap up to the level of the infraorbital nerves exposes the entire
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ba
c
Fig. 42.3 Photo showing intraoral access for maxillectomy.
(a) Yellow arrow demonstrating a low grade mucoepider­moid carcinoma with bone involvement. (b) transoral exci­sion - class II resection performed without access procedure. Immediate implants placed into residual edentulous maxilla.
medial maxilla and nasal cavity. Subsequent osteotomies depend on the resection required. Closure involves rotating the nasal skeleton back in place. Often, no xation is required. Soft tissue closure is similar to a Weber-Fergusson approach and will be discussed below (Fig.42.4).
42.4.4 Transfacial: Weber-Fergusson Approach
The Weber-Fergusson approach (and its various described modications) has been widely used since it was rst described for access. The rst to describe this approach remains unclear, but a clear early mention is to be found in the textbook by Sir William Fergusson from the nineteenth century, System of Practical Surgery [9]. This approach is ideal for class II, III, IV and V maxillectomies. It provides very good access to the anterior maxilla, orbital oor and orbit. Tumours extending posterior to the maxillary tuberos-
d
(c) radial forearm free ap reconstruction after healing with prosthetic bar to retain a full upper denture. (d) facial appear­ance after rehabilitation with adequate tumour clearance and no scarring or residual facial deformity
ity and involving the pterygoid plates may not be as readily accessible with this approach alone. Especially when the tumour extends superiorly towards the skull base, or into the infratemporal fossa, access posteriorly can be improved by a concurrent lip split mandibulotomy, or an additional tempo­ral approach [10, 11]. The step-by-step technique for the Weber-Fergusson approach is described below with hints and tips for each section.
A tarsorrhaphy suture is performed rst to protect the cor­nea during the procedure. The skin markings are made rst, with ink used to mark out particular points to facilitate accu­rate closure. Extension of the incision infraorbitally (within a subciliary or a subtarsal crease) as far as the lateral canthus is commonly known as Dieffenbach’s modication, although it is included in the original gure in Fergusson’s text [9]. Where possible, our preference is to avoid the lateral lower lid extension of the incision, as it increases the risk of lid complications such as ectropion. Hence, especially when the
42 Maxillectomy
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Fig. 42.4 Diagram demonstrating markings for a lateral rhinotomy incision
orbit or orbital oor can be spared, the lip split and lateral rhinotomy alone may provide enough access. The skin inci­sion is similar to the lateral rhinotomy approach described above; however, from the alar, the incision runs inferiorly along the philtrum to the vermillion to perform a ‘lip split’ procedure (Fig.42.5). Extending along the philtrum leads to better cosmetic results than a midline lip split [12].
The incisions commence at the lip and extend up the lat­eral rhinotomy. Care should be taken to cauterise or tie-off the labial vessels as you incise through the lip. When incising around the alar base, it is preferable to either perform the incision 1–2 mm from the alar margins and to direct the blade vertically down toward the maxilla and not under the ala itself. This preserves the attachment of the elastic bres of the alar cartilage to the periosteum of the lateral aspect of the anterior nasal spine. This is believed to reduce the risk of subsequent alar retraction. The lateral rhinotomy incision is carried through the muscular layer to the piriform aperture. In this case, the tumour does not extend into the lateral nasal wall, as described above in the lateral rhinotomy approach, the nasal cavity can be entered here through an incision in the nasal mucosa. In this case, the lateral nasal mucosa can be raised, and a Howarth is inserted to protect the lateral nasal mucosa (Fig.42.6).
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The cheek ap is then raised ensuring that the planned mucosal and soft tissue margin for complete resection is pre­served (Fig.42.7). The infraorbital nerve is then encountered and is often sacriced especially if it is within the planned maxillectomy. In a Class II resection where it can be pre­served, maintaining the infraorbital nerve can limit access. In that situation, an infraorbital osteotomy has been described to mobilize the nerve within its foramen to improve access to the posterior maxilla [13]. In our experience, this is unlikely to be required.
Once the cheek ap is raised, the lateral and posterior access is enough, even for a lesion involving the maxillary tuberosity (Fig.42.8). The remaining soft tissue incisions are then made, including the palatal incision and the posterior incision involving the soft palate. A good rule to apply for all maxillectomies is: Complete as much soft tissue dissection as possible prior to any bony osteotomies. This especially includes the posterior extent/soft palate dissection where a through and through dissection is necessary (Fig.42.8). This will save a lot of time after the bony osteotomies when bleed­ing makes it much harder to see, and time is of the essence.
The osteotomies are then sequentially performed to mobilize the maxilla. Prior to performing the osteotomies, the anaesthetist should be informed to deliver a period of hypotensive anaesthesia and to elevate the head slightly to minimize bleeding. In this class IIB resection, the anterior and palatal osteotomies are performed rst, followed by the high le fort 1 level horizontal osteotomy and then the poste­rior osteotomies through the midpoint of the pterygoid plates (in this case) (Fig.42.9). If the pterygoid plates are to be preserved, then a curved osteotome is used to perform a pterygomaxillary dysjunction. Posterior osteotomies through the pterygoid plates can be performed with an osteotome or a saw. Our preference is to complete these with a reciprocating saw and complete the osteotomies with a large straight osteotome. At this point of the operation, there is often signicant bleeding likely from the main trunk of the internal maxillary artery, or from branches of it. Bleeding cannot be controlled until the resection is com­pleted. Large wooden handle Obwegeser osteotomes can be used to connect the osteotomies and mobilize the maxillec­tomy (Fig. 42.10). Posterior muscular attachments are released with mayo scissors.
Closure of the Weber-Fergusson approach needs to be performed in layers, closing mucosa, then muscle and nally skin (Fig.42.11). Care needs to be taken to ensure the alar is either secured to underlying bone or a plate to avoid exces­sive widening of the alar base.
For higher level Class II and class III resections, an infra­orbital extension or a complete Weber-Fergusson incision may be required. This may also be required for improved access for concurrent reconstruction as it gives better access