Фармакология ноотропных средств. Учебное пособие

ɗɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬ

(Ethylmethylhydroxypyridine succinate)

ɗɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬ

Ȼɟɥɵɣ ɢɥɢ ɛɟɥɵɣ ɫ ɤɪɟɦɨɜɚɬɵɦ ɨɬɬɟɧɤɨɦ ɤɪɢɫɬɚɥɥɢɱɟɫɤɢɣ ɩɨɪɨɲɨɤ Ʌɟɝɤɨ ɪɚɫɬɜɨɪɢɦ ɜ ɜɨɞɟ

Ɏɚɪɦɚɤɨɥɨɝɢɹ ɗɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬ ɨɬɧɨɫɢɬɫɹ ɤ ɤɥɚɫ ɫɭ 3-ɨɤɫɢɩɢɪɢɞɢɧɨɜ ɹɜɥɹɟɬɫɹ ɢɧɝɢɛɢɬɨɪɨɦ ɫɜɨɛɨɞɧɨɪɚɞɢɤɚɥɶɧɵɯ ɩɪɨɰɟɫɫɨɜ ɦɟɦɛɪɚɧɨɩɪɨɬɟɤɬɨɪɨɦ Ɉɛɥɚɞɚɟɬ ɬɚɤɠɟ ɚɧɬɢɝɢɩɨɤɫɢɱɟɫɤɢɦ ɞɟɣɫɬɜɢɟɦ ɩɨɜɵ ɲɚɟɬ ɭɫɬɨɣɱɢɜɨɫɬɶ ɨɪɝɚɧɢɡɦɚ ɤ ɫɬɪɟɫɫɭ

Ɇɟɯɚɧɢɡɦ ɞɟɣɫɬɜɢɹ ɷɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬɚ ɨɛɭɫɥɨɜɥɟɧ ɟɝɨ ɚɧɬɢɨɤɫɢɞɚɧɬɧɵɦ ɢ ɦɟɦɛɪɚɧɨɩɪɨɬɟɤɬɨɪɧɵɦ ɞɟɣɫɬɜɢɟɦ ɉɪɟɩɚɪɚɬ ɢɧɝɢɛɢ ɪɭɟɬ ɩɟɪɟɤɢɫɧɨɟ ɨɤɢɫɥɟɧɢɟ ɥɢɩɢɞɨɜ ɩɨɜɵɲɚɟɬ ɚɤɬɢɜɧɨɫɬɶ ɫɭɩɟɪɨɤɫɢɞɨɤɫɢɞɚ ɡɵ ɩɨɜɵɲɚɟɬ ɫɨɨɬɧɨɲɟɧɢɟ ɥɢɩɢɞ-ɛɟɥɨɤ ɭɥɭɱɲɚɟɬ ɫɬɪɭɤɬɭɪɭ ɢ ɮɭɧɤɰɢɸ ɦɟɦ ɛɪɚɧɵ ɤɥɟɬɨɤ ɗɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬ ɦɨɞɟɥɢɪɭɟɬ ɚɤɬɢɜɧɨɫɬɶ ɦɟɦɛɪɚɧɨɫɜɹɡɚɧɧɵɯ ɮɟɪɦɟɧɬɨɜ ɤɚɥɶɰɢɣ-ɧɟɡɚɜɢɫɢɦɨɣ ɮɨɫɮɨɞɢɷɫɬɟɪɚɡɵ ɚɞɟ ɧɢɥɚɬɰɢɤɥɚɡɵ ɚɰɟɬɢɥɯɨɥɢɧɷɫɬɟɪɚɡɵ ɪɟɰɟɩɬɨɪɧɵɯ ɤɨɦɩɥɟɤɫɨɜ ɛɟɧɡɨɞɢɚɡɟɩɢ ɧɨɜɨɝɨ ȽȺɆɄ ɚɰɟɬɢɥɯɨɥɢɧɨɜɨɝɨ ɱɬɨ ɭɫɢɥɢɜɚɟɬ ɢɯ ɫɩɨɫɨɛɧɨɫɬɶ ɫɜɹɡɵɜɚɧɢɹ ɫ ɥɢɝɚɧɞɚɦɢ ɫɩɨɫɨɛɫɬɜɭɟɬ ɫɨɯɪɚɧɟɧɢɸ ɫɬɪɭɤɬɭɪɧɨ-ɮɭɧɤɰɢɨɧɚɥɶɧɨɣ ɨɪɝɚɧɢɡɚ ɰɢɢ ɛɢɨɦɟɦɛɪɚɧ ɬɪɚɧɫɩɨɪɬɚ ɧɟɣɪɨɦɟɞɢɚɬɨɪɨɜ ɢ ɭɥɭɱɲɟɧɢɸ ɫɢɧɚɩɬɢɱɟɫɤɨɣ ɩɟɪɟɞɚɱɢ ɗɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬ ɩɨɜɵɲɚɟɬ ɫɨɞɟɪɠɚɧɢɟ ɜ ɝɨ ɥɨɜɧɨɦ ɦɨɡɝɟ ɞɨɮɚɦɢɧɚ ȼɵɡɵɜɚɟɬ ɭɫɢɥɟɧɢɟ ɤɨɦɩɟɧɫɚɬɨɪɧɨɣ ɚɤɬɢɜɚɰɢɢ ɚɷɪɨɛ ɧɨɝɨ ɝɥɢɤɨɥɢɡɚ ɢ ɫɧɢɠɟɧɢɟ ɫɬɟɩɟɧɢ ɭɝɧɟɬɟɧɢɹ ɨɤɢɫɥɢɬɟɥɶɧɵɯ ɩɪɨɰɟɫɫɨɜ ɜ ɰɢɤ ɥɟ Ʉɪɟɛɫɚ ɜ ɭɫɥɨɜɢɹɯ ɝɢɩɨɤɫɢɢ ɫ ɭɜɟɥɢɱɟɧɢɟɦ ɫɨɞɟɪɠɚɧɢɹ ɚɞɟɧɨɡɢɧɬɪɢɮɨɫ

71

ɮɨɪɧɨɣ ɤɢɫɥɨɬɵ ȺɌɎ ɢ ɤɪɟɚɬɢɧɮɨɫɮɚɬɚ ɚɤɬɢɜɚɰɢɸ ɷɧɟɪɝɨɫɢɧɬɟɡɢɪɭɸɳɢɯ ɮɭɧɤɰɢɣ ɦɢɬɨɯɨɧɞɪɢɣ

ɉɨɜɵɲɚɟɬ ɪɟɡɢɫɬɟɧɬɧɨɫɬɶ ɨɪɝɚɧɢɡɦɚ ɤ ɜɨɡɞɟɣɫɬɜɢɸ ɪɚɡɥɢɱɧɵɯ ɩɨɜɪɟ ɠɞɚɸɳɢɯ ɮɚɤɬɨɪɨɜ ɩɪɢ ɩɚɬɨɥɨɝɢɱɟɫɤɢɯ ɫɨɫɬɨɹɧɢɹɯ ɝɢɩɨɤɫɢɹ ɢ ɢɲɟɦɢɹ ɧɚɪɭɲɟɧɢɟ ɦɨɡɝɨɜɨɝɨ ɤɪɨɜɨɨɛɪɚɳɟɧɢɹ ɢɧɬɨɤɫɢɤɚɰɢɹ ɷɬɚɧɨɥɨɦ ɢ ɚɧɬɢɩɫɢɯɨɬɢ ɱɟɫɤɢɦɢ ɥɟɤɚɪɫɬɜɟɧɧɵɦɢ ɫɪɟɞɫɬɜɚɦɢ

ȼ ɭɫɥɨɜɢɹɯ ɤɪɢɬɢɱɟɫɤɨɝɨ ɫɧɢɠɟɧɢɹ ɤɨɪɨɧɚɪɧɨɝɨ ɤɪɨɜɨɬɨɤɚ ɫɩɨɫɨɛɫɬɜɭɟɬ ɫɨɯɪɚɧɟɧɢɸ ɫɬɪɭɤɬɭɪɧɨ-ɮɭɧɤɰɢɨɧɚɥɶɧɨɣ ɨɪɝɚɧɢɡɚɰɢɢ ɦɟɦɛɪɚɧ ɤɚɪɞɢɨɦɢɨɰɢ ɬɨɜ ɫɬɢɦɭɥɢɪɭɟɬ ɚɤɬɢɜɧɨɫɬɶ ɦɟɦɛɪɚɧɧɵɯ ɮɟɪɦɟɧɬɨɜ – ɮɨɫɮɨɞɢɷɫɬɟɪɚɡɵ ɚɞɟ ɧɢɥɚɬɰɢɤɥɚɡɵ ɚɰɟɬɢɥɯɨɥɢɧɷɫɬɟɪɚɡɵ ɉɨɞɞɟɪɠɢɜɚɟɬ ɪɚɡɜɢɜɚɸɳɭɸɫɹ ɩɪɢ ɨɫɬɪɨɣ ɢɲɟɦɢɢ ɚɤɬɢɜɚɰɢɸ ɚɰɟɬɢɥɯɨɥɢɧɷɫɬɟɪɚɡɵ ɢ ɚɷɪɨɛɧɨɝɨ ɝɥɢɤɨɥɢɡɚ ɫɩɨ ɫɨɛɫɬɜɭɟɬ ɜ ɭɫɥɨɜɢɹɯ ɝɢɩɨɤɫɢɢ ɜɨɫɫɬɚɧɨɜɥɟɧɢɸ ɦɢɬɨɯɨɧɞɪɢɚɥɶɧɵɯ ɨɤɢɫɥɢ ɬɟɥɶɧɨ-ɜɨɫɫɬɚɧɨɜɢɬɟɥɶɧɵɯ ɩɪɨɰɟɫɫɨɜ ɭɜɟɥɢɱɢɜɚɟɬ ɫɢɧɬɟɡ ȺɌɎ ɢ ɤɪɟɚɬɢɧɮɨɫ ɮɚɬɚ Ɉɛɟɫɩɟɱɢɜɚɟɬ ɰɟɥɨɫɬɧɨɫɬɶ ɦɨɪɮɨɥɨɝɢɱɟɫɤɢɯ ɫɬɪɭɤɬɭɪ ɢ ɮɢɡɢɨɥɨɝɢɱɟɫɤɢɯ ɮɭɧɤɰɢɣ ɢɲɟɦɢɡɢɪɨɜɚɧɧɨɝɨ ɦɢɨɤɚɪɞɚ ɍɥɭɱɲɚɟɬ ɤɥɢɧɢɱɟɫɤɨɟ ɬɟɱɟɧɢɟ ɢɧ ɮɚɪɤɬɚ ɦɢɨɤɚɪɞɚ ɩɨɜɵɲɚɟɬ ɷɮɮɟɤɬɢɜɧɨɫɬɶ ɩɪɨɜɨɞɢɦɨɣ ɬɟɪɚɩɢɢ ɫɧɢɠɚɟɬ ɱɚ ɫɬɨɬɭ ɜɨɡɧɢɤɧɨɜɟɧɢɹ ɚɪɢɬɦɢɢ ɢ ɧɚɪɭɲɟɧɢɣ ɜɧɭɬɪɢɫɟɪɞɟɱɧɨɣ ɩɪɨɜɨɞɢɦɨɫɬɢ

ɇɨɪɦɚɥɢɡɭɟɬ ɦɟɬɚɛɨɥɢɱɟɫɤɢɟ ɩɪɨɰɟɫɫɵ ɜ ɢɲɟɦɢɡɢɪɨɜɚɧɧɨɦ ɦɢɨɤɚɪɞɟ ɩɨɜɵɲɚɟɬ ɚɧɬɢɚɧɝɢɧɚɥɶɧɭɸ ɚɤɬɢɜɧɨɫɬɶ ɧɢɬɪɚɬɨɜ ɭɥɭɱɲɚɟɬ ɪɟɨɥɨɝɢɱɟɫɤɢɟ ɫɜɨɣɫɬɜɚ ɤɪɨɜɢ ɭɦɟɧɶɲɚɟɬ ɩɨɫɥɟɞɫɬɜɢɹ ɪɟɩɟɪɮɭɡɢɨɧɧɨɝɨ ɫɢɧɞɪɨɦɚ ɩɪɢ ɨɫɬɪɨɣ ɤɨɪɨɧɚɪɧɨɣ ɧɟɞɨɫɬɚɬɨɱɧɨɫɬɢ

ɋɩɨɫɨɛɫɬɜɭɟɬ ɫɨɯɪɚɧɟɧɢɸ ɝɚɧɝɥɢɨɡɧɵɯ ɤɥɟɬɨɤ ɫɟɬɱɚɬɤɢ ɢ ɜɨɥɨɤɨɧ ɡɪɢ ɬɟɥɶɧɨɝɨ ɧɟɪɜɚ ɩɪɢ ɩɪɨɝɪɟɫɫɢɪɭɸɳɟɣ ɧɟɣɪɨɩɚɬɢɢ ɩɪɢɱɢɧɚɦɢ ɤɨɬɨɪɨɣ ɹɜɥɹɸɬ ɫɹ ɯɪɨɧɢɱɟɫɤɚɹ ɢɲɟɦɢɹ ɢ ɝɢɩɨɤɫɢɹ ɍɥɭɱɲɚɟɬ ɮɭɧɤɰɢɨɧɚɥɶɧɭɸ ɚɤɬɢɜɧɨɫɬɶ ɫɟɬɱɚɬɤɢ ɢ ɡɪɢɬɟɥɶɧɨɝɨ ɧɟɪɜɚ ɭɜɟɥɢɱɢɜɚɹ ɨɫɬɪɨɬɭ ɡɪɟɧɢɹ

ɍɦɟɧɶɲɚɟɬ ɮɟɪɦɟɧɬɚɬɢɜɧɭɸ ɬɨɤɫɟɦɢɸ ɢ ɷɧɞɨɝɟɧɧɭɸ ɢɧɬɨɤɫɢɤɚɰɢɸ ɩɪɢ ɨɫɬɪɨɦ ɩɚɧɤɪɟɚɬɢɬɟ

ɍɥɭɱɲɚɟɬ ɦɟɬɚɛɨɥɢɡɦ ɢ ɤɪɨɜɨɫɧɚɛɠɟɧɢɟ ɝɨɥɨɜɧɨɝɨ ɦɨɡɝɚ ɦɢɤɪɨɰɢɪɤɭ ɥɹɰɢɸ ɢ ɪɟɨɥɨɝɢɱɟɫɤɢɟ ɫɜɨɣɫɬɜɚ ɤɪɨɜɢ ɭɦɟɧɶɲɚɟɬ ɚɝɪɟɝɚɰɢɸ ɬɪɨɦɛɨɰɢɬɨɜ

ɋɬɚɛɢɥɢɡɢɪɭɟɬ ɦɟɦɛɪɚɧɵ ɤɥɟɬɨɤ ɤɪɨɜɢ ɷɪɢɬɪɨɰɢɬɨɜ ɢ ɬɪɨɦɛɨɰɢɬɨɜ ɫɧɢɠɚɹ ɜɟɪɨɹɬɧɨɫɬɶ ɪɚɡɜɢɬɢɹ ɝɟɦɨɥɢɡɚ Ɉɛɥɚɞɚɟɬ ɝɢɩɨɥɢɩɢɞɟɦɢɱɟɫɤɢɦ ɞɟɣ ɫɬɜɢɟɦ ɡɚ ɫɱɟɬ ɭɦɟɧɶɲɟɧɢɹ ɫɨɞɟɪɠɚɧɢɹ ɨɛɳɟɝɨ ɯɨɥɟɫɬɟɪɢɧɚ ɢ ɥɢɩɨɩɪɨɬɟɢɞɨɜ ɧɢɡɤɨɣ ɩɥɨɬɧɨɫɬɢ

ɉɪɢ ɨɞɧɨɤɪɚɬɧɨɦ ɢ ɤɭɪɫɨɜɨɦ ɩɪɢɟɦɟ ɦɚɤɫɢɦɚɥɶɧɚɹ ɤɨɧɰɟɧɬɪɚɰɢɹ &PD[ ɜ ɩɥɚɡɦɟ ɤɪɨɜɢ ɞɨɫɬɢɝɚɟɬɫɹ ɱɟɪɟɡ ɱ ɉɪɢ ɜɜɟɞɟɧɢɢ ɜ ɞɨɡɟ – ɦɝ&PD[ ɜ ɩɥɚɡɦɟ ɤɪɨɜɢ – 3,5– ɦɤɝ ɦɥ

72

Ȼɵɫɬɪɨ ɪɚɫɩɪɟɞɟɥɹɟɬɫɹ ɜ ɨɪɝɚɧɚɯ ɢ ɬɤɚɧɹɯ ɋɪɟɞɧɟɟ ɜɪɟɦɹ ɭɞɟɪɠɢɜɚɧɢɹ ɷɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬɚ ɜ ɨɪɝɚɧɢɡɦɟ – 0,7– ɱ

Ɇɟɬɚɛɨɥɢɡɢɪɭɟɬɫɹ ɜ ɩɟɱɟɧɢ ɩɭɬɟɦ ɝɥɸɤɭɪɨɧɢɪɨɜɚɧɢɹ ɂɞɟɧɬɢɮɢɰɢɪɨɜɚ ɧɨ ɦɟɬɚɛɨɥɢɬɨɜ -ɨɤɫɢɩɢɪɢɞɢɧɚ ɮɨɫɮɚɬ – ɨɛɪɚɡɭɟɬɫɹ ɜ ɩɟɱɟɧɢ ɢ ɩɪɢ ɭɱɚɫɬɢɢ ɳɟɥɨɱɧɨɣ ɮɨɫɮɚɬɚɡɵ ɪɚɫɩɚɞɚɟɬɫɹ ɧɚ ɮɨɫɮɨɪɧɭɸ ɤɢɫɥɨɬɭ ɢ -ɨɤɫɢɩɢɪɢɞɢɧ 2-ɣ ɦɟɬɚɛɨɥɢɬ – ɮɚɪɦɚɤɨɥɨɝɢɱɟɫɤɢ ɚɤɬɢɜɧɵɣ ɨɛɪɚɡɭɟɬɫɹ ɜ ɛɨɥɶɲɢɯ ɤɨɥɢɱɟ ɫɬɜɚɯ ɢ ɨɛɧɚɪɭɠɢɜɚɟɬɫɹ ɜ ɦɨɱɟ ɧɚ – ɫɭɬ ɩɨɫɥɟ ɜɜɟɞɟɧɢɹ -ɣ – ɜɵɜɨɞɢɬɫɹ ɜ ɛɨɥɶɲɢɯ ɤɨɥɢɱɟɫɬɜɚɯ ɫ ɦɨɱɨɣ -ɣ ɢ -ɣ – ɝɥɸɤɭɪɨɧɤɨɧɴɸɝɚɬɵ

ȼɵɜɨɞɢɬɫɹ ɢɡ ɩɥɚɡɦɵ ɤɪɨɜɢ ɛɵɫɬɪɨ ɢ ɩɪɚɤɬɢɱɟɫɤɢ ɧɟ ɨɩɪɟɞɟɥɹɟɬɫɹ ɱɟɪɟɡɱɚɫɚ ɜ ɧɟɣ Ȼɵɫɬɪɨ ɜɵɜɨɞɢɬɫɹ ɫ ɦɨɱɨɣ ɜ ɨɫɧɨɜɧɨɦ ɜ ɜɢɞɟ ɦɟɬɚɛɨɥɢɬɨɜ % ɡɚ ɱ ɢ ɜ ɧɟɡɧɚɱɢɬɟɥɶɧɨɦ ɤɨɥɢɱɟɫɬɜɟ – ɜ ɧɟɢɡɦɟɧɧɨɦ ɜɢɞɟ ɡɚ ɱ ɉɨɤɚɡɚɬɟɥɢ ɜɵɜɟɞɟɧɢɹ ɫ ɦɨɱɨɣ ɧɟɢɡɦɟɧɟɧɧɨɝɨ ɷɬɢɥɦɟɬɢɥɝɢɞɪɨɤɫɢɩɢɪɢɞɢɧɚ ɫɭɤɰɢɧɚɬɚ ɢ ɦɟɬɚɛɨɥɢɬɨɜ ɢɦɟɸɬ ɢɧɞɢɜɢɞɭɚɥɶɧɭɸ ɜɚɪɢɚɛɟɥɶɧɨɫɬɶ

ɉɨɤɚɡɚɧɢɹ. Ɋɚɫɬɜɨɪ ɞɥɹ ɢɧɴɟɤɰɢɣ ɨɫɬɪɵɟ ɢ ɯɪɨɧɢɱɟɫɤɢɟ ɧɚɪɭɲɟɧɢɹ ɦɨɡ ɝɨɜɨɝɨ ɤɪɨɜɨɨɛɪɚɳɟɧɢɹ ɜ ɬ ɱ ɢɲɟɦɢɱɟɫɤɢɣ ɢɧɫɭɥɶɬ ɢ ɟɝɨ ɩɨɫɥɟɞɫɬɜɢɹ ɞɢɫɰɢ ɪɤɭɥɹɬɨɪɧɚɹ ɷɧɰɟɮɚɥɨɩɚɬɢɹ ɜɟɝɟɬɨɫɨɫɭɞɢɫɬɚɹ ɞɢɫɬɨɧɢɹ ɩɫɢɯɨɫɨɦɚɬɢɱɟɫɤɢɟ ɡɚɛɨɥɟɜɚɧɢɹ ɧɟɜɪɨɬɢɱɟɫɤɢɟ ɢ ɧɟɜɪɨɡɨɩɨɞɨɛɧɵɟ ɪɚɫɫɬɪɨɣɫɬɜɚ ɫ ɩɪɨɹɜɥɟɧɢɟɦ ɬɪɟɜɨɝɢ ɫɬɪɚɯɚ ɷɦɨɰɢɨɧɚɥɶɧɨɝɨ ɧɚɩɪɹɠɟɧɢɹ ɪɚɫɫɬɪɨɣɫɬɜɚ ɩɚɦɹɬɢ ɢ ɜɧɢɦɚɧɢɹ ɧɚɪɭɲɟɧɢɟ ɭɦɫɬɜɟɧɧɨɣ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ ɩɫɢɯɢɱɟɫɤɢɟ ɢ ɧɟɜɪɨɥɨɝɢɱɟɫɤɢɟ ɡɚ ɛɨɥɟɜɚɧɢɹ ɜ ɩɨɠɢɥɨɦ ɜɨɡɪɚɫɬɟ ɚɬɟɪɨɫɤɥɟɪɨɡ ɫɨɫɭɞɨɜ ɝɨɥɨɜɧɨɝɨ ɦɨɡɝɚ ɤɭɩɢɪɨ ɜɚɧɢɟ ɚɥɤɨɝɨɥɶɧɨɝɨ ɚɛɫɬɢɧɟɧɬɧɨɝɨ ɫɢɧɞɪɨɦɚ ɫɨɩɪɨɜɨɠɞɚɸɳɟɝɨɫɹ ɧɟɜɪɨɡɨɩɨ ɞɨɛɧɵɦɢ ɢ ɜɟɝɟɬɚɬɢɜɧɨ-ɫɨɫɭɞɢɫɬɵɦɢ ɪɚɫɫɬɪɨɣɫɬɜɚɦɢ ɨɫɬɪɚɹ ɢɧɬɨɤɫɢɤɚɰɢɹ ɧɟɣɪɨɥɟɩɬɢɤɚɦɢ

Ɍɚɛɥɟɬɤɢ ɢɲɟɦɢɱɟɫɤɚɹ ɛɨɥɟɡɧɶ ɫɟɪɞɰɚ ɤɨɦɩɥɟɤɫɧɚɹ ɬɟɪɚɩɢɹ ɉɨɛɨɱɧɵɟ ɞɟɣɫɬɜɢɹ Ɍɨɲɧɨɬɚ ɫɭɯɨɫɬɶ ɜɨ ɪɬɭ ɚɥɥɟɪɝɢɱɟɫɤɢɟ ɪɟɚɤɰɢɢ ɋɩɨɫɨɛ ɩɪɢɦɟɧɟɧɢɹ ɢ ɞɨɡɵ ɉɚɪɟɧɬɟɪɚɥɶɧɨ ɜ ɦ ɢɥɢ ɜ ɜ ɫɬɪɭɣɧɨ ɢɥɢ ɤɚ

ɩɟɥɶɧɨ ȼ ɜ ɫɬɪɭɣɧɨ ɜ ɬɟɱɟɧɢɟ – ɦɢɧ ɢɥɢ ɤɚɩɟɥɶɧɨ – ɤɚɩɟɥɶ ɜ ɦɢɧɭɬɭ ɜ

ɤɚɱɟɫɬɜɟ ɪɚɫɬɜɨɪɢɬɟɥɹ ɩɪɢɦɟɧɹɸɬ ɮɢɡɢɨɥɨɝɢɱɟɫɤɢɣ ɪɚɫɬɜɨɪ ɧɚɬɪɢɹ ɯɥɨɪɢɞɚ Ɋɟɠɢɦ ɞɨɡɢɪɨɜɚɧɢɹ ɩɨɞɛɢɪɚɸɬ ɢɧɞɢɜɢɞɭɚɥɶɧɨ ɇɚɱɚɥɶɧɚɹ ɞɨɡɚ ɩɨ – ɦɝ 1– ɪɚɡɚ ɜ ɫɭɬɤɢ ɞɚɥɟɟ ɞɨɡɭ ɩɨɫɬɟɩɟɧɧɨ ɩɨɜɵɲɚɸɬ ɞɨ ɩɨɥɭɱɟɧɢɹ ɬɟɪɚɩɟɜɬɢɱɟ ɫɤɨɝɨ ɷɮɮɟɤɬɚ Ɇɚɤɫɢɦɚɥɶɧɚɹ ɞɨɡɚ – ɞɨ ɦɝ ɫɭɬ

Ɉɫɬɪɨɟ ɧɚɪɭɲɟɧɢɟ ɦɨɡɝɨɜɨɝɨ ɤɪɨɜɨɨɛɪɚɳɟɧɢɹ ɜ ɫɨɫɬɚɜɟ ɤɨɦɩɥɟɤɫɧɨɣ ɬɟɪɚɩɢɢ – ɜ ɜ ɤɚɩɟɥɶɧɨ – ɦɝ ɫɭɬ ɜ ɩɟɪɜɵɟ – ɞɧɹ ɡɚɬɟɦ ɜ ɦ ɩɨ ɦɝɪɚɡɚ ɜ ɫɭɬɤɢ ɉɪɨɞɨɥɠɢɬɟɥɶɧɨɫɬɶ ɥɟɱɟɧɢɹ – 10– ɫɭɬ

Ⱦɢɫɰɢɪɤɭɥɹɬɨɪɧɚɹ ɷɧɰɟɮɚɥɨɩɚɬɢɹ ɮɚɡɚ ɞɟɤɨɦɩɟɧɫɚɰɢɢ ɜ ɜ ɫɬɪɭɣɧɨ ɢɥɢ ɤɚɩɟɥɶɧɨ ɩɨ ɦɝ – ɪɚɡɚ ɜ ɫɭɬɤɢ ɜ ɬɟɱɟɧɢɟ ɞɧɟɣ ɡɚɬɟɦ ɩɪɨɞɨɥɠɚɸɬ ɜɜɟ

73

ɞɟɧɢɟ ɜ ɦ ɩɨ ɦɝ ɫɭɬ ɜ ɬɟɱɟɧɢɟ ɞɧɟɣ ɉɪɨɮɢɥɚɤɬɢɤɚ ɞɢɫɰɢɪɤɭɥɹɬɨɪɧɨɣ ɷɧɰɟɮɚɥɨɩɚɬɢɢ ɜ ɦ ɩɨ ɦɝ ɪɚɡɚ ɜ ɫɭɬɤɢ ɜ ɬɟɱɟɧɢɟ – ɞɧɟɣ

Ʌɟɝɤɢɟ ɤɨɝɧɢɬɢɜɧɵɟ ɧɚɪɭɲɟɧɢɹ ɭ ɛɨɥɶɧɵɯ ɩɨɠɢɥɨɝɨ ɜɨɡɪɚɫɬɚ ɬɪɟɜɨɠ ɧɵɟ ɪɚɫɫɬɪɨɣɫɬɜɚ ɜ ɦ – ɦɝ ɫɭɬ ɜ ɬɟɱɟɧɢɟ – ɞɧɟɣ

Ⱥɛɫɬɢɧɟɧɬɧɵɣ ɫɢɧɞɪɨɦ ɩɨ – ɦɝ ɜ ɦ – ɪɚɡɚ ɜ ɫɭɬɤɢ ɢɥɢ ɜ ɜ ɤɚ ɩɟɥɶɧɨ 1– ɪɚɡɚ ɜ ɫɭɬɤɢ ɜ ɬɟɱɟɧɢɟ – ɞɧɟɣ

Ɉɫɬɪɚɹ ɢɧɬɨɤɫɢɤɚɰɢɹ ɧɟɣɪɨɥɟɩɬɢɤɚɦɢ ɜ ɜ – ɦɝ ɫɭɬ ɜ ɬɟɱɟɧɢɟ 7– ɞɧɟɣ

Ɉɫɬɪɵɣ ɩɚɧɤɪɟɨɧɟɤɪɨɡ ɩɟɪɢɬɨɧɢɬ ɩɪɢɦɟɧɹɟɬɫɹ ɜ ɩɪɟɞ- ɢ ɩɨɫɥɟɨɩɟɪɚɰɢ ɨɧɧɨɦ ɩɟɪɢɨɞɟ ɪɟɠɢɦ ɞɨɡɢɪɨɜɚɧɢɹ ɡɚɜɢɫɢɬ ɨɬ ɪɚɫɩɪɨɫɬɪɚɧɟɧɧɨɫɬɢ ɩɪɨɰɟɫɫɚ ɬɹɠɟɫɬɢ ɫɨɫɬɨɹɧɢɹ

ȼɧɭɬɪɶ ɩɨ ɝ ɪɚɡɚ ɜ ɫɭɬɤɢ ɉɪɨɞɨɥɠɢɬɟɥɶɧɨɫɬɶ ɤɭɪɫɚ – ɧɟ ɦɟɧɟɟɦɟɫ ɉɨɜɬɨɪɧɵɟ ɤɭɪɫɵ – ɩɨ ɪɟɤɨɦɟɧɞɚɰɢɢ ɜɪɚɱɚ

Ɏɨɪɦɚ ɜɵɩɭɫɤɚ Ɍɚɛɥɟɬɤɢ ɩɨɤɪɵɬɵɟ ɩɥɟɧɨɱɧɨɣ ɨɛɨɥɨɱɤɨɣ ɦɝ ɪɚɫɬɜɨɪ ɞɥɹ ɜɧɭɬɪɢɜɟɧɧɨɝɨ ɢ ɜɧɭɬɪɢɦɵɲɟɱɧɨɝɨ ɜɜɟɞɟɧɢɹ ɦɝ ɦɥ

ɋɚɥɶɛɭɬɢɚɦɢɧ

[4-[(4-ɚɦɢɧɨ-2-ɦɟɬɢɥ-ɩɢɪɢɦɢɞɢɧ-5-ɢɥ ɦɟɬɢɥ-ɮɨɪɦɢɥ-ɚɦɢɧɨ@-3-[2-[(4-ɚɦɢɧɨ-2-ɦɟɬɢɥ- ɩɢɪɢɦɢɞɢɧ-5-ɢɥ ɦɟɬɢɥ-ɮɨɪɦɢɥ-ɚɦɢɧɨ]-5-(2-ɦɟɬɢɥɩɪɨɩɚɧɨɢɥɨɤɫɢ)ɩɟɧɬ-2-ɟɧ-3- ɢɥ]ɞɢɫɭɥɶɮɚɧɢɥ-ɩɟɧɬ-3-ɟɧɢɥ] 2-ɦɟɬɢɥɩɪɨɩɚɧɨɚɬ

Ɏɚɪɦɚɤɨɥɨɝɢɹ ɋɚɥɶɛɭɬɢɚɦɢɧ – ɫɪɟɞɫɬɜɨ ɪɟɝɭɥɢɪɭɸɳɟɟ ɦɟɬɚɛɨɥɢɱɟɫɤɢɟ ɩɪɨɰɟɫɫɵ ɜ ɐɇɋ ɩɪɟɞɫɬɚɜɥɹɟɬ ɫɨɛɨɣ ɨɪɢɝɢɧɚɥɶɧɭɸ ɦɨɥɟɤɭɥɭ ɫɢɧɬɟɡɢɪɨɜɚɧ ɧɭɸ ɩɭɬɟɦ ɦɨɞɢɮɢɤɚɰɢɣ ɬɢɚɦɢɧɚ ɫɢɧɬɟɬɢɱɟɫɤɨɟ ɫɨɟɞɢɧɟɧɢɟ ɛɥɢɡɤɨɟ ɩɨ ɫɬɪɨ ɟɧɢɸ ɤ ɬɢɚɦɢɧɭ ɞɢɦɟɪ ɞɜɭɯ ɦɨɞɢɮɢɰɢɪɨɜɚɧɧɵɯ ɦɨɥɟɤɭɥ ɬɢɚɦɢɧɚ ɢɦɟɟɬ ɨɬ ɤɪɵɬɵɣ ɬɢɚɡɨɥɶɧɵɣ ɰɢɤɥ ɞɨɩɨɥɧɢɬɟɥɶɧɭɸ ɞɢɫɭɥɶɮɢɞɧɭɸ ɫɜɹɡɶ ɢ ɥɢɩɨɮɢɥɶ ɧɵɣ ɷɮɢɪ Ȼɥɚɝɨɞɚɪɹ ɷɬɢɦ ɦɨɞɢɮɢɤɚɰɢɹɦ ɫɚɥɶɛɭɬɢɚɦɢɧ ɫɩɨɫɨɛɟɧ ɩɪɨɧɢɤɚɬɶ

74

ɱɟɪɟɡ ȽɗȻ ɢ ɧɚɤɚɩɥɢɜɚɬɶɫɹ ɜ ɫɬɪɭɤɬɭɪɚɯ ɝɨɥɨɜɧɨɝɨ ɦɨɡɝɚ ɱɬɨ ɨɛɭɫɥɨɜɥɢɜɚɟɬ ɬɚɤɢɟ ɷɮɮɟɤɬɵ ɩɪɟɩɚɪɚɬɚ ɤɚɤ ɭɥɭɱɲɟɧɢɟ ɤɨɨɪɞɢɧɚɰɢɢ ɞɜɢɠɟɧɢɣ ɩɨɜɵɲɟɧɢɟ ɪɟɡɢɫɬɟɧɬɧɨɫɬɢ ɤ ɭɬɨɦɥɟɧɢɸ ɦɵɲɰ ɭɥɭɱɲɟɧɢɟ ɪɟɡɢɫɬɟɧɬɧɨɫɬɢ ɤɨɪɵ ɝɨɥɨɜɧɨɝɨ ɦɨɡɝɚ ɤ ɯɪɨɧɢɱɟɫɤɨɣ ɝɢɩɨɤɫɢɢ ɤɢɫɥɨɪɨɞɧɨɟ ɝɨɥɨɞɚɧɢɟ ɭɥɭɱɲɟɧɢɟ ɤɨɧɰɟɧ ɬɪɚɰɢɢ ɜɧɢɦɚɧɢɹ ɢ ɫɩɨɫɨɛɧɨɫɬɢ ɤ ɡɚɩɨɦɢɧɚɧɢɸ ɋɭɥɶɛɭɬɢɚɦɢɧ ɭɥɭɱɲɚɟɬ ɩɚ ɦɹɬɶ ɩɨɫɪɟɞɫɬɜɨɦ ɭɫɢɥɟɧɢɹ ɯɨɥɢɧɟɪɝɢɱɟɫɤɨɣ ɞɨɮɚɦɢɧɷɪɝɢɱɟɫɤɨɣ ɢ ɝɥɭɬɚɦɚ ɬɟɪɝɢɱɟɫɤɨɣ ɩɟɪɟɞɚɱ Ɉɛɥɚɞɚɟɬ ɜɵɫɨɤɨɣ ɷɮɮɟɤɬɢɜɧɨɫɬɶɸ ɩɪɢ ɫɢɦɩɬɨɦɚɬɢɱɟ ɫɤɨɦ ɥɟɱɟɧɢɢ ɛɨɥɶɧɵɯ ɫ ɮɭɧɤɰɢɨɧɚɥɶɧɵɦɢ ɚɫɬɟɧɢɱɟɫɤɢɦɢ ɫɨɫɬɨɹɧɢɹɦɢ

ɋɚɥɶɛɭɬɢɚɦɢɧ ɛɵɫɬɪɨ ɜɫɚɫɵɜɚɟɬɫɹ &PD[ ɜ ɩɥɚɡɦɟ ɤɪɨɜɢ ɞɨɫɬɢɝɚɟɬɫɹ ɱɟ ɪɟɡ –2 ɱ ɩɨɫɥɟ ɩɪɢɟɦɚ 7ò ɫɨɫɬɚɜɥɹɟɬ ɨɤɨɥɨ ɱ ɋɚɥɶɛɭɬɢɚɦɢɧ ɜɵɜɨɞɢɬɫɹ ɫ ɦɨɱɨɣ

ɉɨɤɚɡɚɧɢɹ Ʌɟɱɟɧɢɟ ɮɢɡɢɱɟɫɤɨɣ ɢ ɩɫɢɯɢɱɟɫɤɨɣ ɚɫɬɟɧɢɢ ɫɨɩɪɨɜɨɠɞɚɸ ɳɟɣɫɹ ɚɩɚɬɢɟɣ ɢ ɫɧɢɠɟɧɢɟɦ ɚɤɬɢɜɧɨɫɬɢ Ⱦɚɧɧɨɟ ɥɟɤɚɪɫɬɜɟɧɧɨɟ ɫɪɟɞɫɬɜɨ ɧɟ ɢɫ ɤɥɸɱɚɟɬ ɧɟɨɛɯɨɞɢɦɨɫɬɢ ɧɚɡɧɚɱɟɧɢɹ ɚɧɬɢɞɟɩɪɟɫɫɚɧɬɨɜ ɜ ɫɥɭɱɚɟ ɩɨɞɬɜɟɪɠɞɟɧɢɹ ɭ ɩɚɰɢɟɧɬɚ ɞɟɩɪɟɫɫɢɜɧɨɝɨ ɷɩɢɡɨɞɚ

ɋɩɨɫɨɛ ɩɪɢɦɟɧɟɧɢɹ ɢ ɞɨɡɵ Ⱦɥɹ ɩɟɪɨɪɚɥɶɧɨɝɨ ɩɪɢɦɟɧɟɧɢɹ ɉɪɟɩɚɪɚɬ ɩɪɟɞɧɚɡɧɚɱɟɧ ɞɥɹ ɩɪɢɦɟɧɟɧɢɹ ɬɨɥɶɤɨ ɜɡɪɨɫɥɵɦɢ ɩɨ - ɬɚɛɥɟɬɤɢ ɜ ɫɭɬɤɢ Ɍɚɛ ɥɟɬɤɢ ɫɥɟɞɭɟɬ ɩɪɢɧɢɦɚɬɶ ɰɟɥɢɤɨɦ ɜɨ ɜɪɟɦɹ ɡɚɜɬɪɚɤɚ ɢ ɨɛɟɞɚ ɡɚɩɢɜɚɹ ɞɨɫɬɚɬɨɱ ɧɵɦ ɤɨɥɢɱɟɫɬɜɨɦ ɜɨɞɵ ɉɪɨɞɨɥɠɢɬɟɥɶɧɨɫɬɶ ɥɟɱɟɧɢɹ ɧɟ ɞɨɥɠɧɚ ɩɪɟɜɵɲɚɬɶ ɧɟɞɟɥɢ Ⱦɟɬɢ ɉɪɟɩɚɪɚɬ ɧɟ ɩɪɢɦɟɧɹɬɶ ɭ ɞɟɬɟɣ

Ɏɨɪɦɚ ɜɵɩɭɫɤɚ Ɍɚɛɥɟɬɤɢ ɩɨɤɪɵɬɵɟ ɨɛɨɥɨɱɤɨɣ ɦɝ

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ɁȺȾȺɇɂə ȾɅə ɋȺɆɈɋɌɈəɌȿɅɖɇɈɃ ɊȺȻɈɌɕ

ɌȿɈɊȿɌɂɑȿɋɄɂȿ ȼɈɉɊɈɋɕ

1.ɉɭɬɢ ɮɚɪɦɚɤɨɥɨɝɢɱɟɫɤɨɣ ɤɨɪɪɟɤɰɢɢ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ Ɉɛɳɚɹ ɤɥɚɫ ɫɢɮɢɤɚɰɢɹ ɫɪɟɞɫɬɜ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ

2.ɉɫɢɯɨɫɬɢɦɭɥɢɪɭɸɳɢɟ ɫɪɟɞɫɬɜɚ Ʉɨɮɟɢɧ Ɇɟɯɚɧɢɡɦ ɞɟɣɫɬɜɢɹ ɨɬɞɟɥɶ ɧɵɯ ɩɪɟɩɚɪɚɬɨɜ ɧɚ ɤɥɟɬɨɱɧɨɦ ɢ ɫɢɫɬɟɦɧɨɦ ɭɪɨɜɧɹɯ ɉɨɤɚɡɚɧɢɹ ɤ ɩɪɢɦɟɧɟɧɢɸ ɉɨɛɨɱɧɵɟ ɷɮɮɟɤɬɵ

3.ɋɪɟɞɫɬɜɚ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ ɧɟ ɢɫɬɨɳɚɸɳɟɝɨ ɬɢɩɚ ɞɟɣ ɫɬɜɢɹ Ɇɟɯɚɧɢɡɦ ɢ ɨɫɨɛɟɧɧɨɫɬɢ ɜɥɢɹɧɢɹ ɧɚ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɶ ɨɬɞɟɥɶɧɵɯ ɩɪɟ ɩɚɪɚɬɨɜ ɉɨɤɚɡɚɧɢɹ ɤ ɩɪɢɦɟɧɟɧɢɸ

4.ɇɨɨɬɪɨɩɧɵɟ ɫɪɟɞɫɬɜɚ Ɉɩɪɟɞɟɥɟɧɢɟ ɤɥɚɫɫɢɮɢɤɚɰɢɹ ɨɫɧɨɜɧɵɟ ɷɮɮɟɤɬɵ

5.ɉɨɤɚɡɚɧɢɹ ɤ ɩɪɢɦɟɧɟɧɢɸ ɧɨɨɬɪɨɩɧɵɯ ɫɪɟɞɫɬɜ

6.Ɉɛɳɟɬɨɧɢɡɢɪɭɸɳɢɟ ɫɪɟɞɫɬɜɚ ɢ ɚɞɚɩɬɨɝɟɧɵ Ʉɥɚɫɫɢɮɢɤɚɰɢɹ Ɇɟɯɚ ɧɢɡɦɵ ɞɟɣɫɬɜɢɹ ɉɪɢɦɟɧɟɧɢɟ ɇɟɠɟɥɚɬɟɥɶɧɵɟ ɷɮɮɟɤɬɵ

ɉɊȺɄɌɂɑȿɋɄȺə ɊȺȻɈɌȺ

ȼɵɛɟɪɢɬɟ ɩɪɟɩɚɪɚɬ ɢ ɜɵɩɢɲɢɬɟ ɪɟɰɟɩɬ:

1.Ⱦɥɹ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ ɩɪɢ ɚɫɬɟɧɢɢ ɢ ɜɵɩɢɲɢɬɟ ɪɟɰɟɩɬ

2.Ⱦɥɹ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ ɩɪɢ ɧɟɞɨɫɬɚɬɤɟ ɫɧɚ.

3.Ⱦɥɹ ɩɨɜɵɲɟɧɢɹ ɭɦɫɬɜɟɧɧɨɣ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ.

4.Ɋɚɫɬɢɬɟɥɶɧɵɣ ɚɞɚɩɬɨɝɟɧɧɵɣ ɩɪɟɩɚɪɚɬ ɞɥɹ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛ ɧɨɫɬɢ ɜ ɧɟɛɥɚɝɨɩɪɢɹɬɧɵɯ ɭɫɥɨɜɢɹɯ ɪɟɡɤɚɹ ɫɦɟɧɚ ɤɥɢɦɚɬɢɱɟɫɤɢɯ ɩɨɹɫɨɜ ɝɢɩɨ ɤɫɢɹ .

5.ɉɟɩɬɢɞɧɨɣ ɫɬɪɭɤɬɭɪɵ ɩɪɢ ɧɚɪɭɲɟɧɢɢ ɚɞɚɩɬɚɰɢɢ ɩɪɢ ɬɹɠɟɥɨɦ ɫɬɪɟɫɫɟ.

ɌȿɋɌɈȼɕȿ ȼɈɉɊɈɋɕ

ȼɵɛɪɚɬɶ ɨɞɢɧ ɩɪɚɜɢɥɶɧɵɣ ɨɬɜɟɬ

1 Ɇɟɯɚɧɢɡɦ ɩɫɢɯɨɫɬɢɦɭɥɢɪɭɸɳɟɝɨ ɞɟɣɫɬɜɢɹ ɤɨɮɟɢɧɚ ɫɜɹɡɚɧ ɫ ɚ ɢɧɝɢɛɢɪɨɜɚɧɢɟɦ ɦɨɧɨɚɦɢɧɨɤɫɢɞɚɡɵ; ɛ ɛɥɨɤɚɞɨɣ Ⱥ-1-ɚɞɟɧɨɡɢɧɨɜɵɯ ɪɟɰɟɩɬɨɪɨɜ; ɜ ɩɪɹɦɨɣ ɚɤɬɢɜɚɰɢɟɣ ɚɥɶɮɚ-ɚɞɪɟɧɨɪɟɰɟɩɬɨɪɨɜ; ɝ ɚɤɬɢɜɚɰɢɟɣ Ⱥ-1-ɚɞɟɧɨɡɢɧɨɜɵɯ ɪɟɰɟɩɬɨɪɨɜ; ɞ ɚɤɬɢɜɚɰɢɟɣ ɮɨɫɮɨɞɢɷɫɬɟɪɚɡɵ.

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2 ɋ ɱɟɦ ɫɜɹɡɚɧɨ ɩɫɢɯɨɬɪɨɩɧɨɟ ɞɟɣɫɬɜɢɟ ɧɨɨɬɪɨɩɧɵɯ ɩɪɟɩɚɪɚɬɨɜ ɩɪɨɢɡ ɜɨɞɧɵɯ ɨɤɫɢɩɢɪɪɨɥɢɞɨɧɚ"

ɚ ɚɤɬɢɜɚɰɢɟɣ ɞɨɮɚɦɢɧɨɜɵɯ ɪɟɰɟɩɬɨɪɨɜ; ɛ ɚɤɬɢɜɚɰɢɟɣ ɚɞɪɟɧɨɪɟɰɟɩɬɨɪɨɜ; ɜ ɪɚɫɲɢɪɟɧɢɟɦ ɦɨɡɝɨɜɵɯ ɫɨɫɭɞɨɜ;

ɝ ɭɥɭɱɲɟɧɢɟɦ ɷɧɟɪɝɟɬɢɱɟɫɤɨɝɨ ɢ ɩɥɚɫɬɢɱɟɫɤɨɝɨ ɨɛɦɟɧɚ ɜ ɦɨɡɝɨɜɨɣ ɬɤɚɧɢ; ɞ ɚɤɬɢɜɚɰɢɟɣ ȽȺɆɄ-ɪɟɰɟɩɬɨɪɨɜ.

3 Ɇɟɯɚɧɢɡɦ ɧɨɨɬɪɨɩɧɨɝɨ ɞɟɣɫɬɜɢɹ ɩɢɪɚɰɟɬɚɦɚ ɜɤɥɸɱɚɟɬ ɜɫɟ ɩɟɪɟɱɢɫ ɥɟɧɧɨɟ ɤɪɨɦɟ

ɚ ɭɥɭɱɲɟɧɢɹ ɩɨɝɥɨɳɟɧɢɹ ɝɥɸɤɨɡɵ ɧɟɪɜɧɵɦɢ ɤɥɟɬɤɚɦɢ; ɛ ɚɤɬɢɜɚɰɢɢ ɫɢɧɬɟɡɚ ɊɇɄ ɛɟɥɤɚ ɮɨɫɮɨɥɢɩɢɞɨɜ ɜ ɐɇɋ; ɜ ɭɥɭɱɲɟɧɢɹ ɮɭɧɤɰɢɨɧɢɪɨɜɚɧɢɹ ɦɢɬɨɯɨɧɞɪɢɣ; ɝ ɬɨɪɦɨɠɟɧɢɹ ȽȺɆɄ-ɟɪɝɢɱɟɫɤɨɣ ɩɟɪɟɞɚɱɢ ɜ ɐɇɋ; ɞ ɩɨɜɵɲɟɧɢɹ ɭɫɬɨɣɱɢɜɨɫɬɢ ɦɨɡɝɚ ɤ ɝɢɩɨɤɫɢɢ ɢ ɬɨɤɫɢɱɟɫɤɢɦ ɜɨɡɞɟɣɫɬɜɢɹɦ.

4 Ʉɚɤɨɣ ɩɪɟɩɚɪɚɬ ɨɛɥɚɞɚɟɬ ɫɥɟɞɭɸɳɢɦɢ ɫɜɨɣɫɬɜɚɦɢ ɨɤɚɡɵɜɚɟɬ ɩɫɢɯɨ ɫɬɢɦɭɥɢɪɭɸɳɟɟ ɞɟɣɫɬɜɢɟ ɜɵɡɵɜɚɟɬ ɬɚɯɢɤɚɪɞɢɸ ɩɨɜɵɲɚɟɬ ɚɪɬɟɪɢɚɥɶɧɨɟ ɞɚɜ ɥɟɧɢɟ ɢɫɬɨɳɚɟɬ ɮɭɧɤɰɢɨɧɚɥɶɧɵɟ ɢ ɷɧɟɪɝɟɬɢɱɟɫɤɢɟ ɪɟɡɟɪɜɵ ɨɪɝɚɧɢɡɦɚ"

ɚ ɤɨɮɟɢɧ; ɛ ɤɨɪɬɟɤɫɢɧ; ɜ ɧɚɫɬɨɣɤɚ ɠɟɧɶɲɟɧɹ; ɝ ɩɢɪɚɰɟɬɚɦ.

5 Ʉɚɤɨɣ ɩɪɟɩɚɪɚɬ ɨɛɥɚɞɚɟɬ ɫɥɟɞɭɸɳɢɦɢ ɫɜɨɣɫɬɜɚɦɢ ɨɤɚɡɵɜɚɟɬ ɭɦɟɪɟɧ ɧɨɟ ɩɫɢɯɨɫɬɢɦɭɥɢɪɭɸɳɟɟ ɞɟɣɫɬɜɢɟ ɪɚɫɲɢɪɹɟɬ ɫɨɫɭɞɵ ɦɵɲɰ ɢ ɦɢɨɤɚɪɞɚ ɬɨ ɧɢɡɢɪɭɟɬ ɜɟɧɵ ɫɬɢɦɭɥɢɪɭɟɬ ɮɭɧɤɰɢɢ ɫɟɪɞɰɚ ɭɜɟɥɢɱɢɜɚɟɬ ɞɢɭɪɟɡ ɩɪɢ ɞɥɢ ɬɟɥɶɧɨɦ ɩɪɢɦɟɧɟɧɢɢ ɢɫɬɨɳɚɟɬ ɮɭɧɤɰɢɨɧɚɥɶɧɵɟ ɢ ɷɧɟɪɝɟɬɢɱɟɫɤɢɟ ɪɟɡɟɪɜɵ ɨɪ ɝɚɧɢɡɦɚ"

ɚ ɚɦɢɬɪɢɩɬɢɥɢɧ; ɛ ɤɨɮɟɢɧ; ɜ ɩɢɪɚɰɟɬɚɦ; ɝ ɬɨɮɢɡɨɩɚɦ; ɞ ɮɥɭɨɤɫɟɬɢɧ.

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6 ɍɤɚɠɢɬɟ ɩɪɟɩɚɪɚɬɵ ɨɛɥɚɞɚɸɳɢɟ ɜɵɪɚɠɟɧɧɵɦ ɚɞɚɩɬɨɝɟɧɧɵɦ ɞɟɣɫɬɜɢɟɦ ɚ ɧɚɫɬɨɣɤɚ ɠɟɧɶɲɟɧɹ ɷɤɫɬɪɚɤɬ ɷɥɟɭɬɟɪɨɤɨɤɤɚ; ɛ ɧɚɫɬɨɣɤɚ ɩɭɫɬɵɪɧɢɤɚ ɷɤɫɬɪɚɤɬ ɥɟɜɡɟɢ; ɜ ɧɚɫɬɨɣɤɚ ɥɢɦɨɧɧɢɤɚ ɩɚɧɬɨɤɪɢɧ; ɝ ɷɤɫɬɪɚɤɬ ɪɨɞɢɨɥɵ ɧɚɫɬɨɣɤɚ ɚɪɚɥɢɢ.

7 ɍɤɚɠɢɬɟ ɩɨɤɚɡɚɧɢɟ ɤ ɩɪɢɦɟɧɟɧɢɸ ɩɢɪɚɰɟɬɚɦɚ ɚ ɞɥɹ ɷɤɫɬɪɟɧɧɨɝɨ ɩɨɜɵɲɟɧɢɹ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɢ; ɛ ɧɚɪɭɲɟɧɢɹ ɫɧɚ; ɜ ɞɟɬɹɦ ɫ ɨɬɫɬɚɜɚɧɢɟɦ ɜ ɭɦɫɬɜɟɧɧɨɦ ɪɚɡɜɢɬɢɢ; ɝ ɤɭɩɢɪɨɜɚɧɢɟ ɫɭɞɨɪɨɝ; ɞ ɩɫɢɯɨɡ ɫ ɛɪɟɞɨɦ ɝɚɥɥɸɰɢɧɚɰɢɹɦɢ.

8 Ʉɚɤɨɣ ɩɪɟɩɚɪɚɬ ɨɛɥɚɞɚɟɬ ɫɥɟɞɭɸɳɢɦɢ ɫɜɨɣɫɬɜɚɦɢ ɩɨɫɥɟ ɤɭɪɫɨɜɨɝɨ ɩɪɢɟɦɚ ɨɤɚɡɵɜɚɟɬ ɭɦɟɪɟɧɧɨɟ ɨɛɳɟɬɨɧɢɡɢɪɭɸɳɟɟ ɞɟɣɫɬɜɢɟ ɭɫɤɨɪɹɟɬ ɚɞɚɩɬɚ ɰɢɸ ɨɪɝɚɧɢɡɦɚ ɤ ɪɚɡɥɢɱɧɵɦ ɧɟɛɥɚɝɨɩɪɢɹɬɧɵɦ ɮɚɤɬɨɪɚɦ ɫɪɟɞɵ ɩɨɜɵɲɚɟɬ ɢɦ ɦɭɧɢɬɟɬ"

ɚ ɷɤɫɬɪɚɤɬ ɷɥɟɭɬɟɪɨɤɨɤɤɚ; ɛ ɧɚɫɬɨɣɤɚ ɥɢɦɨɧɧɢɤɚ; ɜ ɷɤɫɬɪɚɤɬ ɥɟɜɡɟɢ; ɝ ɧɚɫɬɨɣɤɚ ɩɭɫɬɵɪɧɢɤɚ; ɞ ɤɨɮɟɢɧ.

9 ɍɤɚɠɢɬɟ ɩɨɤɚɡɚɧɢɟ ɤ ɩɪɢɦɟɧɟɧɢɸ ɨɛɳɟɬɨɧɢɡɢɪɭɸɳɢɯ ɫɪɟɞɫɬɜ ɢ ɚɞɚɩ ɬɨɝɟɧɨɜ

ɚ ɞɟɩɪɟɫɫɢɜɧɨɟ ɫɨɫɬɨɹɧɢɟ; ɛ ɚɫɬɟɧɢɱɟɫɤɨɟ ɫɨɫɬɨɹɧɢɟ; ɜ ɛɟɫɫɨɧɧɢɰɚ; ɝ ɧɟɜɪɨɬɢɱɟɫɤɨɟ ɫɨɫɬɨɹɧɢɟ.

ȼɵɛɪɚɬɶ ɧɟɫɤɨɥɶɤɨ ɩɪɚɜɢɥɶɧɵɯ ɨɬɜɟɬɨɜ

10 Ⱦɟɣɫɬɜɢɟ ɩɫɢɯɨɦɨɬɨɪɧɵɯ ɫɬɢɦɭɥɹɬɨɪɨɜ ɢɡ ɝɪɭɩɩɵ ɚɞɪɟɧɨɦɢɦɟɬɢɤɨɜ ɧɚ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɶ ɯɚɪɚɤɬɟɪɢɡɭɟɬɫɹ

ɚ ɭɥɭɱɲɟɧɢɟɦ ɫɤɨɪɨɫɬɧɵɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɪɚɡɥɢɱɧɵɯ ɜɢɞɨɜ ɞɟɹɬɟɥɶɧɨɫɬɢ; ɛ ɭɥɭɱɲɟɧɢɟɦ ɤɚɱɟɫɬɜɟɧɧɵɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɫɥɨɠɧɨɣ ɭɦɫɬɜɟɧɧɨɣ ɞɟɹ

ɬɟɥɶɧɨɫɬɢ;

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ɜ ɛɵɫɬɪɨɣ ɦɨɛɢɥɢɡɚɰɢɟɣ ɪɟɡɟɪɜɧɵɯ ɜɨɡɦɨɠɧɨɫɬɟɣ ɨɪɝɚɧɢɡɦɚ; ɝ ɭɜɟɥɢɱɟɧɢɟɦ ɬɟɩɥɨɩɪɨɞɭɤɰɢɢ; ɞ ɭɥɭɱɲɟɧɢɟɦ ɩɟɪɟɧɨɫɢɦɨɫɬɢ ɯɨɥɨɞɚ.

11 Ⱦɟɣɫɬɜɢɟ ɩɢɪɚɰɟɬɚɦɚ ɧɚ ɪɚɛɨɬɨɫɩɨɫɨɛɧɨɫɬɶ ɯɚɪɚɤɬɟɪɢɡɭɟɬɫɹ ɚ ɭɥɭɱɲɟɧɢɟɦ ɫɤɨɪɨɫɬɧɵɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɪɚɡɥɢɱɧɵɯ ɜɢɞɨɜ ɞɟɹɬɟɥɶɧɨɫɬɢ; ɛ ɭɥɭɱɲɟɧɢɟɦ ɤɚɱɟɫɬɜɟɧɧɵɯ ɯɚɪɚɤɬɟɪɢɫɬɢɤ ɫɥɨɠɧɨɣ ɭɦɫɬɜɟɧɧɨɣ ɞɟɹ

ɬɟɥɶɧɨɫɬɢ; ɜ ɭɦɟɧɶɲɟɧɢɟɦ ɬɪɟɜɨɝɢ ɫɬɪɚɯɚ ɢ ɩɚɧɢɱɟɫɤɢɯ ɪɟɚɤɰɢɣ; ɝ ɭɫɤɨɪɟɧɢɟɦ ɜɨɫɫɬɚɧɨɜɥɟɧɢɹ ɩɨɫɥɟ ɢɫɬɨɳɚɸɳɢɯ ɧɚɝɪɭɡɨɤ; ɞ ɭɥɭɱɲɟɧɢɟɦ ɩɟɪɟɧɨɫɢɦɨɫɬɢ ɝɢɩɨɤɫɢɢ.

12 ɍɤɚɠɢɬɟ ɷɮɮɟɤɬɵ ɯɚɪɚɤɬɟɪɧɵɟ ɞɥɹ ɩɢɪɚɰɟɬɚɦɚ ɚ ɚɧɬɢɩɫɢɯɨɬɢɱɟɫɤɢɣ; ɛ ɫɨɫɭɞɨɪɚɫɲɢɪɹɸɳɢɣ; ɜ ɧɨɨɬɪɨɩɧɵɣ; ɝ ɩɪɨɬɢɜɨɫɭɞɨɪɨɠɧɵɣ; ɞ ɚɧɬɢɝɢɩɨɤɫɢɱɟɫɤɢɣ.

13 ɍɤɚɠɢɬɟ ɪɚɫɬɢɬɟɥɶɧɵɟ ɩɪɟɩɚɪɚɬɵ ɨɛɥɚɞɚɸɳɢɟ ɩɪɟɢɦɭɳɟɫɬɜɟɧɧɨ ɨɛɳɟɬɨɧɢɡɢɪɭɸɳɢɦ ɞɟɣɫɬɜɢɟɦ

ɚ ɧɚɫɬɨɣɤɚ ɠɟɧɶɲɟɧɹ; ɛ ɧɚɫɬɨɣɤɚ ɩɭɫɬɵɪɧɢɤɚ; ɜ ɷɤɫɬɪɚɤɬ ɷɥɟɭɬɟɪɨɤɨɤɤɚ; ɝ ɧɚɫɬɨɣɤɚ ɥɢɦɨɧɧɢɤɚ; ɞ ɷɤɫɬɪɚɤɬ ɥɟɜɡɟɢ.

Ʉɚɤɢɦɢ ɢɡ ɩɟɪɟɱɢɫɥɟɧɧɵɯ ɫɜɨɣɫɬɜ ɨɛɥɚɞɚɟɬ ɩɢɪɚɰɟɬɚɦ" ɚ ɭɫɬɪɚɧɹɟɬ ɩɫɢɯɨɦɨɬɨɪɧɨɟ ɜɨɡɛɭɠɞɟɧɢɟ; ɛ ɨɤɚɡɵɜɚɟɬ ɛɥɚɝɨɩɪɢɹɬɧɨɟ ɫɬɢɦɭɥɢɪɭɸɳɟɟ ɜɥɢɹɧɢɟ ɧɚ ɭɦɫɬɜɟɧɧɭɸ ɞɟɹ

ɬɟɥɶɧɨɫɬɶ ɩɪɢ ɯɪɨɧɢɱɟɫɤɢɯ ɫɨɫɭɞɢɫɬɵɯ ɢ ɞɟɝɟɧɟɪɚɬɢɜɧɵɯ ɩɨɪɚɠɟɧɢɹɯ ɝɨɥɨɜɧɨ ɝɨ ɦɨɡɝɚ;

ɜ ɨɤɚɡɵɜɚɟɬ ɚɧɬɢɝɢɩɨɤɫɢɱɟɫɤɨɟ ɞɟɣɫɬɜɢɟ; ɝ ɜɵɪɚɠɟɧɧɵɟ ɤɥɢɧɢɱɟɫɤɢɟ ɷɮɮɟɤɬɵ ɪɚɡɜɢɜɚɸɬɫɹ ɱɟɪɟɡ ɞɧɟɣ ɩɪɢɟɦɚ; ɞ ɷɮɮɟɤɬ ɪɚɡɜɢɜɚɟɬɫɹ ɭɠɟ ɩɨɫɥɟ ɩɪɢɟɦɚ ɩɟɪɜɨɣ ɞɨɡɵ.

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Ʉ ɧɨɨɬɪɨɩɧɵɦ ɩɪɟɩɚɪɚɬɚɦ ɨɬɧɨɫɹɬɫɹ ɚ ɤɨɮɟɢɧ; ɛ ɚɦɢɧɚɥɨɧ;

ɜ ɧɚɫɬɨɣɤɚ ɷɥɟɭɬɟɪɨɤɨɤɤɚ; ɝ ɜɢɧɩɨɰɟɬɢɧ; ɞ ɩɢɪɚɰɟɬɚɦ.

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