1. Erythema exudativum multiforme;

2. Pemphigus vulgaris;

3. Herpes simplex;

4. Toxicodermia;

5. Duhring's disease.

52. A 55 years old patient complains of a pain during food intake, presence of erosions on mucous membranes of the mouth. She was ill more than a month ago.

Objectively: there are large erosion of bright red colour on unchanged cover of gums, the soft palate and arculus. Mucous easily is traumatized and exfoliated at a place of friction. In impression smears - Tzanck's cells are found. What is your diagnose?

1. Duhring's disease;

2. Lyell's syndrome;

3. Erythema exudativum multiforme;

4. Stevens-Johnson syndrome;

5. Pemphigus vulgaris.

53. A 44 years old patient complains of unpleasant sensations in a throat at swallowing, hoarse voices, and eruptions of bullas on her skin surface of the trunk. She was sick for 2 months. At first there were unpleasant sensations in a throat and a hoarseness and then noticed bullas on a skin. She doesn’t know what the cause of illness was. She treated herself by rinsing with decoction of plants, smearing with Lugol's iodine. There was some improvement periodically, but all symptoms of disease did not disappear. What is the most possible preliminary diagnosis?

1. Acantholytic pemphigus;

2. Duhring's disease;

3. Secondary syphilis;

4. Herpes zoster;

5. Erythema exudativum multiforme.

54. A 47 years old patient complains of a pain in oral cavity. The pain increases at food intake and talking.

Objectively: bilateral oval erosions form against an unaltered background in retromolar zone, painful during palpation. Nikolsky's sign is positive. What is the most probable diagnosis?

1. Erythema exudativum multiforme;

2. Chronic recurrent aphthous stomatitis;

3. Acute herpetic stomatitis;

4. Pemphigus vulgaris;

5. Bullous form of lichen ruber planus.

55. A 60 years old patient complains of the general weakness, a body temperature 37,5ºС throughout days, occurrence itching eruptions. During examination of the skin of a trunk, buttocks, inguinal-femoral folds there were revealed grouped, tense vesicles and bullas in size from a pea to the wood nut, papules on erythemal background, with serous exudation. Peripheral lymph nodes were increased, a dense consistence. In blood and contents of bullas and vesicles – eosinophilia. What is the most probable diagnosis?

1. Allergic dermatitis;

2. True acute eczema;

3. Vulgar pemphigus;

4. Duhring's disease;

5. Erythema exudativum multiforme.

Lesson 18

Methods for examination of a patient in venereal diseases. The causative agent of syphilis. Conditions and routes of infection with syphilis. Pathogenesis. Experimental syphilis. Classification.

1. Treponema pallidum was discovered in:

1. 1885;

2. 1890;

3. 1895;

4. 1905;

5. 1910.

2. What method of diagnosing is used in everyday practice for the reveal of T. pallidum?

1. Cultivation on nutrient mediums;

2. Staining by the Romanovsky-Giemsa;

3. Staining by methylene blue;

4. Examination of native preparations in dark field illumination of the microscope;

5. Silvering By the Morozov.

3. T. pallidum is a microorganism of:

1. Spiral shaped;

2. Globe-shaped;

3. Rod-shaped;

4. Thread shaped;

5. Irregular shape.

4. Which possible routes of infection with syphilis can be?

1. Sexual;

2. Community acquired;

3. Transfusion of blood;

4. Faecal-oral;

5. Transplacental.

5. What physiological secretion and excreta can be contagious in syphilis?

1. Saliva;

2. Sweat;

3. Urine;

4. Milk;

5. Sperm.

6. T. pallidum has such types of its movements:

1. Back and forth;

2. All-round;

3. Rotatory;

4. Pendulum-like;

5. Wave-like.

7. How many spirals has T. pallidum?

1. 2-4;

2. 6-8;

3. 8-14;

4. 14-16;

5. 16-18.

8. The incubation period in syphilis lasts:

1. 2-4 years;

2. 3-4 weeks;

3. 6-8 weeks;

4. 10 days;

5. 9-12 weeks.

9. The cause of a prolonged incubation period in syphilis can be intake of: