Secondary hyperpigmentation maculae;

Erosion;

Crusts;

Scars;

Lichenification.

Patients with Duhring's disease complain on:

Pain;

Itch;

Sensation of a fall of temperature of extremities;

Sensation of crawling of “horripilation” on skin surface;

Parasthesia.

Factors of etiology and pathogenesis in the toxico-allergic form of erythema exudativum multiforme can be:

Herpes-virus infection;

Tetracycline;

The causative agent of parotitis;

Mycoplasma;

Vaccines.

What is the most important diagnostic symptom for diagnosis of pemphigus:

Koebner's phenomenon;

Nikolsky's sign;

Baltser's iodine test;

Mantoux test;

Isomorphic reaction.

Smears of acantholytic cells (Tzanck) are painted:

By the Gram-method;

By the Ziehl-Neelsen method;

By the Romanovsky-Giemsa;

By the Burri method;

By the Morozov method.

In what bullous dermatosis patients very often have gluten sensitivity?

Vulgar pemphigus;

Pemphigus foliaceus;

Duhring's disease;

The Stevens-Johnson syndrome;

Pemphigus seborrhoicus.

For treatment patients with erythema exudativum multiforme such medicines are prescribed:

Salicylates;

Antibiotics;

Hormonal corticosteroid preparations;

Immunosuppressants;

Diaminodiphenylsulphones (DDS).

In what layer of a skin can bullas locate in true pemphigus?

Papillary layer;

Basal layer;

Prickle-cell layer;

Granular layer;

Horny layer.

Bullae in Duhring's disease are always located:

Subcorneal bulla;

Intraepidermal bulla;

Subepidermal bulla;

Subdermal bulla;

Subhypodermal bulla.

Select the description that characterize the diagnosis of Duhring's disease:

One or several maculae of bright red colour leaving persistent pigmentation;

Erythemal maculae with cyanotic hue in the centre which slightly sinks down. Patient feels burning and itching;

Bullae, erosion, Nikolsky's sign is positive;

Papules, bullae, vesicles, crusts.

Acantholytic Tzanck cells are revealed by means of research:

Histological;

Bacteriological;

Cytological;

Fluorescent;

Serological.

Erythema exudativum multiforme is characterized by such clinical signs:

Inflammatory maculae;

Bullae;

Absent of symptoms;

Affection of a skin and mucous membranes;

Affection of joints.

It is necessary to differentiate Duhring's disease with:

Psoriasis;

Scabies;

Pemphigus vulgaris;

Toxico-allergic dermatitis;

Eczema.

The most characteristic morphological elements for Duhring's disease are:

Erythematous maculae;

Papulae;

Bullae;

Vesicles;

All above-listed is true.

Acantholysis – it is:

Melting of intercellular connections in the prickle-cell layer;

Degenerative changes are in the prickle-cell layer;

Increase of horny layer;

Growth of granular layer;

Disturbance of process of keratinization and occurrence of nucleus in cells of horny layer.

What is the primary morphological element, typical for a pemphigus vulgaris:

Bulla;

Microvesicle;

Papula;

Wheal;

Pustule.

Pathohistological changes (acantholysis) in case of localization of lesions in a pemphigus vulgaris on the oral mucosa are found in:

Granular layer;

Stratum spinosum;

Germinative layer;

Lamina propria;

Submucosa.

The most typical localization of lesions in case of true pemphigus is:

Scalp;

Face;

Oral mucosa;

Elbows and knees;

Palms and soles.

For confirmation of diagnosis of dermatosis herpetiformis it is necessary to conduct a skin test for determination of the heightened sensibility to:

Sulphonamides;

Antibiotics;

Novocaine ;

Iodides;

Bromide.

What signs are characteristic for dermatosis herpetiformis?

Recurrent course;

Polymorphism of rash;

Intense itch;

Positive Nikolsky's sign;

Frequent affection of mucous membranes.

What clinical forms are related to the acantholytic pemphigus?

Vulgaris;

Psoriasiform;

Vegetans;

Pustular;

Seborrhoicus.

It is necessary to differentiate pemphigus vulgaris with:

Stevens-Johnson syndrome;

Psoriasis;

Lyele’s syndrome;

Duhring's disease;

Scabies.

What is the most effective drug for treatment of pemphigus patients?

Penicillin;

Sulphadimethoxin;

Phthivazid;

Prednisolone;

Delagil.

For treatment of Duhring's disease are most often prescribed:

Antibiotics;

Vitamin;

Antihistaminics;

Preparations of the sulphone series (DDS);

Antimalarial agents.

In the case of external treatment of Duhring's disease such medicines are prescribed:

1-2% Sol. Methyleni coerulei;

2-5% iodine tincture;

Ointments containing corticosteroid;

33% sulphur ointment;

2% salicylic acid ointment.

In case of long duration intake of hormonal corticosteroid preparations it is necessary to prescribe:

Diet with limitation of carbohydrates;

Antihistaminics;

Potassium preparations;

Calcium preparations;

Gastroprotectors.

For external treatment of the oral mucosa in pemphigus vulgaris such medicines are prescribed:

Solutions of aniline dyes;

Application of vitamin А;

Application of hormonal corticosteroid ointments;

Adherent dental paste “Solcoseril”;

All above-listed is true.

Such complications can appear in case of long duration intake of hormonal corticosteroid preparations:

Stomach ulcer;

Diabetes;

Osteoporosis;

Disturbance from cardiovascular system;

Immunity decrease.

For external treatment of the skin in pemphigus vulgaris such medicines are prescribed: