Lesson 10 Collagenoses. Lupus erythematosus. Sclerodermia. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention.

1. It is considered the basic theory of etiology of lupus erythematosus is:

1. Infectious;

2. Parasitic;

3. Allergic;

4. Autoimmune.

2. What lesions are characteristic for chronic lupus erythematosus?

1. Crusts;

2. Maculae;

3. Atrophy;

4. Excoriations.

3. What lesions are characteristic for chronic lupus erythematosus?

1. Maculae;

2. Lichenification;

3. Scales;

4. Excoriations.

4. What lesions are characteristic for chronic lupus erythematosus?

1. Scars;

2. Atrophy;

3. Crusts;

4. Erosion.

5. What lesions are characteristic for chronic lupus erythematosus?

1. Scales;

2. Maculae;

3. Nodule;

4. Ulcer.

6. What lesions are characteristic for scleroderma?

1. Maculae;

2. Pustules;

3. Atrophy;

4. Excoriations.

7. What lesions are characteristic for scleroderma?

1. Atrophy;

2. Maculae;

3. Papules;

4. Fissures.

8. What clinical forms of chronic lupus erythematosus are distinguished?

1. Discoid;

2. Disseminated;

3. Foliaceous;

4. Verrucous.

9. What clinical forms of chronic lupus erythematosus are distinguished?

1. Disseminated;

2. Biett's erythema centrifugum;

3. Vegetans;

4. Papulonecrotic.

10. What is the favoured localization of rash at patients with discoid variety of lupus erythematosus?

1. Face;

2. Lower extremities;

3. Scalp;

4. Upper extremities.

11. What histomorphological changes in epidermis cause a clinical picture at patients with chronic lupus erythematosus?

1. Follicular hyperkeratosis;

2. Atrophy of germinative layer of epidermis;

3. Parakeratosis;

4. Spongiosis.

12. Choose diagnostic symptoms, characteristic for discoid lupus erythematosus:

1. Besnier-Meshchersky's sign;

2. The “ladies heel” sign;

3. Nikolsky's sign;

4. Auspitz' sign.

13. What are the clinical signs of Biett's erythema centrifugum?

1. Erythema;

2. Scales;

3. Atrophy;

4. Pigmentation.

14. What are the basic clinical signs of acute form of systemic lupus erythematosus?

1. The appearance erythema as a butterfly;

2. Endocarditis;

3. Polyarthritis ;

4. Leucocytosis.

15. What are the basic clinical signs of acute form of systemic lupus erythematosus?

1. Polyneuritis;

2. Haemorrhagic rash;

3. Thrombocytosis;

4. Thrombopenia.

16. What are the basic clinical signs of acute form of systemic lupus erythematosus?

1. Pericarditis;

2. Haemolytic anemia;

3. Proteinuria;

4. Tubercles.

17. What drugs it is necessary to prescribe for treatment of chronic lupus erythematosus?

1. Delagil;

2. Penicillin;

3. Nizoral;

4. Griseofulvin.

18. For treatment of chronic lupus erythematosus such vitamins mainly are applied:

1. C;

2. РР;

3. В12;

4. В1.

19. For external treatment of chronic lupus erythematosus such ointments are applied:

1. Corticosteroid;

2. Antimycotic;

3. Vitaminous;

4. Antiparasitic.

20. What drugs are prescribed for treatment of acute systemic lupus erythematosus?

1. Prednisolone;

2. Delagil;

3. Methotrexate;

4. Nizoral.

21. For treatment of systemic lupus erythematosus such vitamins mainly are applied:

1. С;

2. В₁₂;

3. В₆;

4. РР.

22. For external treatment of chronic lupus erythematosus such ointments are applied:

1. Antiparasitic;

2. Antimycotic;

3. Corticosteroid;

4. Vitaminous.

23. What clinical forms of scleroderma are distinguished?

1. Seborrhoicus;

2. Plaque;

3. Linear;

4. Systemic.

24. What form of scleroderma occurs more frequent than all in child's age?

1. Discoid;

2. Linear;

3. Erythrodermic;

4. Systemic.

25. What pathological condition contributing to the occurrence of scleroderma?

1. Disturbance of synthesis of collagen;

2. Disturbance of exchange of collagen;

3. Disturbance of microcirculation;

4. Defects of the immune system.

26. What are the basic initiating agents of occurrence of scleroderma?

1. Chronic infection;

2. Endocrine dysfunction;

3. Stresses;

4. Overcooling.

27. What stages are distinguished in the development of scleroderma?