Adrenoblocker agents

1. The patient suffering from idiopathic hypertensia, had the acompanyng diseases: ciliary arruthmia, stenocardia, and chronic bronchitis. The physician has decided to use a drug from the group of beta-adrenoblockers. Which agent should be used , taking into account the acompanyng diseases?

A. *Metoprololum

B. Timololum

C. Anaprinilum

D. Pindololum

E. Oxprenololum

2. A patient who had been suffering from arterial hypertension was treated with the drug which mechanism of action is connected with exhaustion of noradrenalin content in sympathetic nerve endings. Indicate this drug.

A. *Reserpinum

B. Clopheinum

C. Anaprinilum

D. Prazosine

E. Dibazolum

3. A 40 year old patient suffers from arterial hypertension with hyperkinetic type of circulation and increased level of renin, sternocardia, sinus tachycardia. Indicate the group of drugs which is more preferable for treatment of this patient.

A. *beta-adrenoblockers

B. Organic nitrates

C. α-adrenoblockers

D. Sympatholytics

E. Ganglion blockers

4. Indicate the drug which possesses hypotensive action exactly due to decrease of vascular tone. What drug can be used?

A. *α-adrenoblocker

B. N-cholinoblocker

C. α- β - adrenoblocker

D. M-cholinoblocker

E. β-adrenoblocker

5. Indicate the group of drugs to which prazosine belongs.

A. *α-adrenoblockers

B. Cardioselective β-adrenoblockers

C. Nonselective beta-adrenoblockers

D. Sympatholytics

E. Angiotensin converting enzyme inhibitors

6. A 40-years-old patient suffers from cardiovascular diseases: arterial hypertension of hyperkinetic type and high blood renin level, stenocardia and sinus tachycardia. Indicate the most expedient group of drugs for treat­ment of the patient?

A. *beta-adrenoblockers

B. Organic nitrates

C. alfa-adrenoblockers

D. Sympatholytics

E. Ganglion blockers

7. Indicate the state in which nonselective beta-adrenoblockers are contraindicated?

A. *Bronchial asthma

B. Thyrotoxicosis

C. Cardiomyopathy

D. Myocardial infarction

E. Arterial hypertension

8. Anaprilin (propranolol) was administered to a patient with hyper­tension that normalized BP fast. What is the mechanism of action of this drug?

A. *Blockade of beta₁- and beta2-adrenoceptors

B. Blockade of beta₁- adrenoceptors

C. Inhibition of phosphodiesterase

D. Blockade of alfa₁-adrenoceptors

E. Stimulation of atfa₂-adrenoceptors

9. Аnарrilin was administered to a patient with arterial hypertension accompanied by obstructive bronchitis. After that the attack of bronchospasm occurred in the patient. Indicate the reason of this side-effect.

A. *Blockade of beta 2-adrenoceptors of bronchi

B. Stimulation of beta 2-adrenoceptors of bronchi

C. Blockade of alfa 2-adrenoceptors of bronchi

D. Blockade of beta1-adrenoceptors of bronchi

E. Stimulation of alfa 1-adrenoceptors of bronchi

10. Therapeutic effect of beta-adrenoblocker propranolol during the treatment of stenocadia is explained by:

A. *Decrease of myocardium oxygen demand

B. Inhibition of catecholamines' production

C. Dilation of coronary arteries

D. Increase of sensibility to catecholamines

E. Increase of peripheral arteries resistance

11. Examination of the 42-years-old women revealed stenocardia with following signs: BP = 170/100 mmHg, heart rate - 84lmin, on ECG -extrasystoles. Which drug from listed below is the most suitable for treat­ment?

A. *Anaprilinum (propranolol)

B. Euphillinum (aminophilline)

C. Nitroglycerin

D. Carbocromen

E. Papaverine

12. Beta-adrenoblocker was prescribed to a patient for the treatment of ischemic heart disease but after some time cough and bronchospasm occured. Indicate the agent which was administered?

A. *Anaprilinum (propranolol)

B. Talinolol

C. Atenolol

D. Phenigidin (nifedipine)

E. Metoprolol

13. A patient suffers from arterial hypertension accompanied by chronic obstructive bronchitis. Indicate hypotensive agent which is contraindi­cated for the patient ?

A. *Anaprilinum (propranolol)

B. Prazosine

C. Nifedipin

D. Dichfothiazidum (hydrochlorthiazide)

E. Captopril

14. Which of the following antiarrhythmic drug is contraindicated for the patient with cardiac arrhythmia accompanied by bronchial asthma?

A. *Anaprilinum (propranolol)

B. Verapamil

C. Aimalin

D. Nifedipin

E. Novocainamidum (procainamide)

15. Ischemic heart disease accom­panied by cardiac arrhythmia was diagnosed in a 50 years-old patient. Indicate the group of drugs which should be administered?

A. *Beta-adrenoblockers

B. Alfa-adrenoblockers

C. Beta-adrenomimetics

D. Alfa-adrenomimetics

E. Sympatholytics

16. An agent causing decrease of noradrenaline content in vesicles of sympathetic nerve endings was admin­istered to a patient suffering from arterial hypertension. Indicate this drug ?

A. *Reserpin

B. Anaprilin (propranolol)

C. Pirroxanum

D. Dibazolum (bendazole)

E. Clophelinum

17. A 50 years old woman suffer­ing from hypertension has taken a drug. In an hour BP was increased, but in 2 hours it started to decrease. Indicate the drug.

A. *Octadine (guanethidine)

B. Reserpine

C. Prazosin

D. Dibazolum (bendazole)

E. Propranolol

18. A patient with arterial hyper­tension has been treating with reserpine for a long period of time. 2-3 weeks ago he began to notice stomachache, heartburn, nausea. Indicate the group of drugs which are able to eliminate these symptoms?

A. *M-cholinoblockers

B. Astringent drugs

C. Antacids

D. Proton pump inhibitors

E. H₂-histaminoblockers

19. Elongation of P-Q interval was revealed on ECG. Indicate the drug which can cause this effect.

A. *Atenolol

B. Prazosin

C. Reserpine

D. Qctadinum (guanethidine)

E. Phentoiamine

20. A patient who had been suffer­ing from severe form of arterial hyper­tension after examination received diagnosis of pheochromocytoma (tumor of adrenal medulla which is accompanied by increased synthesis of adrenaline). Indicate the group of drugs which should be administered to a patient before surgical treatment.

A. *alpha-adrenoblockers

B. Calcium channel blockers

C. Sympatholytics

D. Ganglion blockers

E. beta-adrenoblockers