1. Recombinant vaccine

2. Associated vaccine

3. Eubiotic

4. Chemical vaccine

5. Autovaccine

B-2 recombinant vaccine is used for hepatitis B prevention. It is made from yeasts which genome has been integrated with one gene of hepatitis B antigens. Name the antigen against which immunity will be formed:

1. HBsAg

2. HBcAg

3. HBeAg

4. HBsAg and HBeAg

5. HBeAg and HBcAg

LB/ Hospital ordered medicines in pharmacy company that were used for diagnostics of infectious diseases. These medicines are used to reveal infectious allergic state of patient. What is the name of such medicines?

1. Allergenes

2. Diagnosticum

3. Diagnostic sera

4. Immunoglobulines

5. Toxoids

“2012” LB/ immune sera are used for seroprophylaxis and serotherapy of infectious diseases. What type of immunity is formed with them?

1. Artificial passive immunity

2. Natural active immunity

3. Artificial active immunity

4. Natural passive immunity

5. Species innate immunity

LB/ Patient with trauma was passively prevented against wound infection after primary surgery of wound. Which medicine is used for this?

1. Immune serum

2. Toxoid

3. Normal serum

4. Alive vaccine

5. Antibiotics

LB/ At practical usage of therapeutic antitoxic sera patient is always injected with exact doses. Which unit is used for detection activity of such sera?

1. International

2. Hemolytic

3. Bacteriostatic

4. Lethal

5. Flocculating

LB/ A preparation made from the blood of hyper immunized horses and used for treatment and prevention of tetanus is produced at pharmaceutical plant. What is active component of this medicine?

1. Gamma-globulin

2. Toxoid

3. Interferon

4. Complement

5. Fibronectin

LB/ A patient with severe trauma was made with surgical wound cleaning and given with antitetanus serum. What type of immunity has been formed in result of injection of this medicine?

1. Acquired passive

2. Acquired active

3. Natural passive

4. Natural active

5. Innate species

LB/ due to case of measles infection there is necessity to manage prevention measures in student group. Which medicine should be used to create artificial passive immunity?

1. Normal human immunoglobulin

2. Inactivated vaccine

3. Alive vaccine

4. DPT vaccine

5. Anti measles serum

LB/ A patient with acute form of infectious disease needs current injection of immune serum. To prevent anaphylactic shock it must be given gradually with great carefulness. Which method is used for it?

1. By Bezredka

2. By Erlich

3. By Remer

4. By Ramon

5. By Aujesko

b-12

A pregnant woman was registered in an antenatal clinic and underwent complex examination for a number of infections. Blood serum contained IgM to the rubella virus. What is this result

indicative of?

A Of primary infection

B Of a chronic process

C The woman is healthy

D Of exacerbation of a chronic disease

E Of recurring infection with rubella virus

Vaccines and immune sera

75.“08””10” A toxin inactivated with formaldehyde (0,4%) at 37-40⁰C for 4 weeks is used for vaccination. At first such medicine was used by Ramon for diphtheria prevention. Which kind of medicine is this?

1. Immunoglobulin

2. Inactivated (killed) vaccine

3. Toxoid

4. Antitoxic serum

5. Adjuvant

76.65/ the young adult, 20 years-old male, has been injected with toxoid with prevention purpose. Which from named diseases was prevented?

1. Tuberculosis

2. Diphtheria

3. Scarlet fever

4. Meningitis

5. Whooping cough (pertussis)

77.“04” After 8 days of antitoxic antidiphthericum serum injection a child, suffering from diphtheria, has fever (38 С), joint pain, rash and itching. Which reason of these clinical signs is?

1. Delayed type of hypersensitivity

2. Contact allergy

3. Atopy

4. Serum illness

5. Anaphylaxis

78.25/ Prophylactic vaccination of a student's group was necessary because of a case of diphtheria. What preparation should be used to develop artificial active immunity?

A. Diphtheria toxoid.

B. Antidiphtheritic serum.

C. Specific immunoglobulin.

D.Vaccine from alive bacteria.

E. Inactivated vaccine.

“2013” A 10-year-old child cut his leg with a piece of dirty glass and was sent to a hospital for anti-tetanus serum injection. In order to prevent the development of anaphylactic shock the Bezredka`s desensitization method was applied. What mechanism underlies this method?

1. Binding of IgE receptors on the mast cells

2. Inhibition of the synthesis of mast cellsmediators

3. Stimulation of the immunological antigen tolerance

4. Binding to IgE fixed to mast cells

5. Stimulation of antigen-specific IgG2 synthesis