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III. Vocabulary and Speech Exercises

I. Give English equivalents of the following words and word-combinations.

Рідина; прийом, поширення та виведення ліків; розрізняти; стерильний; що спричиняє подразнення; голка; несталий; вазоконстрикція (звуження кровоносних судин); внутрішньом’язовий; олійний розчин; нерв; протипоказаний; антикоагулянтна терапія; внутрішньовенний; ін’єкція; пристрій, що вживлюється; хіміотерапія; тромболітик; розчиняти; протипухлинний засіб; доступ; внутрішньокістковий; внутрішньосуглобовий; внутрішньоочеревинний.

II. Explain the meaning of the following words and word-combinations.

Pharmacology; toxicology; pharmacokinetics; pharmacodynamics; physiological effect; systemic effect; emergency; ophthalmic solution; circulatory state; vasodilation; intra-arterial; pediatrics; intraspinal; intrapleural.

III. Form synonymous pairs from the words given below.

  • Route, poison, aqueous, fluid, emergency, rate, variable, fast, oily, clot, cancer, to drain, difficult, purpose, location.

  • Toxin, speed, urgency, rapid, changeable, fatty, thrombus, malignant tumour, liquid, aim, site, watery, path, hard, to flow.

IV. Discuss pros and cons of the parenteral route of drug administration.

The most common injections are intravenous (IV), intramuscular (IM), and subcutaneous (subcut).

Advantages:

  • Fast: 15-30 seconds for IV, 3-5 minutes for IM and subcut;

  • 100% bioavailability;

  • Suitable for drugs not absorbed by the gut or those that are too irritant (anti-cancer);

  • One injection can be formulated to last days or even months (Depo-Provera, a birth control shot that works for three months);

  • IV can deliver continuous medication (morphine for patients in continuous pain, or saline drip for people needing fluids).

Disadvantages:

  • Onset of action is quick, hence more risk of addiction when it comes to injecting drugs of abuse;

  • Patients are not typically able to self-administer;

  • Belonephobia, the fear of needles and injection;

  • If needles are shared, there is risk of HIV and other infectious diseases;

  • It is the most dangerous route of administration because it bypasses most of the body’s natural defenses, exposing the user to health problems such as hepatitis, abscesses, infections, and undissolved particles or additives/contaminants;

  • If not done properly, potentially fatal air boluses (bubbles) can occur;

  • Need for strict asepsis.

V. Memorize the meaning of the following prefix.

intra- [Intrq] – prefix of Latin origin denoting within, inside

VI. Skim the text once more looking for the words having the prefix intra- in their structure. Give their definitions.

VII. Read the definition and fill in the blanks with the words given in brackets. Consult the glossary.

  1. Existing or occurring within an atom or atoms – ________________________.

  2. Situated or occurring inside a cell or cells – ____________________________.

  3. Occurring within a molecule or molecules – ____________________________.

  4. Situated or occurring within a nucleus – _______________________________.

  5. Within the uterus – _____________________________________________.

  6. Within a chamber, such as the anterior or posterior chamber of the eye – _____.

  7. Within the skull – ______________________________________________.

  8. Of or relating to the area within the eyeball – ___________________________.

(Intranuclear, intra-atomic, intramolecular, intracellular, intrauterine, intracameral, intra-ocular, intracranial)