a large amount of oxygen is a red colour whilst blood with a shortage of oxygen is of a bluer tinge. If an artery is cut bright red blood spurts out, if a vein is cut then dark blood oozes out.

Carriage of Carbon Dioxide

A small amount of the carbon dioxide may be dissolved in the plasma but the majority is carried in chemical combination with water in the form of carbonic acid.

CO2 + H2O  H2CO3

Our blood is naturally acidic because of the presence of this carbonic acid. An acidic basis is required to allow the easy release of oxygen from oxyhaemoglobin to tissues. A reduction in the acidity of the blood which can occur when there is insufficient carbon dioxide in the blood, as when hyperventilating (see Chapter 3 - Oxygen and Respiration), interferes with the release of oxygen to the tissues.

The Circulation System

The function of the circulatory system, which particularly concerns the aviator, is the carriage of oxygen to the tissues and the removal of carbon dioxide. Oxygen is required by the tissues for oxidation of food. Whereas the major source of energy for the body is carbohydrates which are a component of our food, energy can also be derived from proteins and fats. Thus those on hunger strike inevitably utilize proteins for energy.

Carbohydrates are composed only of the elements carbon, hydrogen and oxygen and in the tissues these foodstuffs combine with Oxygen to give energy:

Carbohydrates + Oxygen  Energy + CO2 + H2O

This process whereby energy is released from food, takes place in the cells and is called Internal

Respiration.

Oxygen is obtained from the atmosphere and the blood picks up the oxygen from the lungs for transport around the body. Follow the path of the circulatory system as shown in Figure 2.2. The largest and most muscular part of the heart is the left ventricle. Blood containing oxygen is sent around the body from the left ventricle when it contracts. A system of one-way valves in the heart prevents blood going the wrong way.

The oxygenated blood passes through the aorta into the major arteries which divide into the smaller arteries before arriving at the smallest vessels of the system - the capillaries. The capillaries have very thin walls (only one cell thick) which allow the passage of oxygen from the blood into the tissues by diffusion (Fick’s Law). They also allow carbon dioxide and water vapour to diffuse in the reverse direction.

The Circulation System 2

Factors Determining Pulse Rate

The pulse rate will increase or decrease resulting from a number of factors as the demand for oxygen varies. Among the principal factors are:

•Exercise.

•Altitude.

•Temperature.

The pulse rate can also vary as a result of the sympathetic/parasympathetic control of the heart. This is discussed in Chapter 6. Among these factors are:

•Fight or Flight (GAS) Syndrome.

•Shock.

•Emotion (fear, anxiety and anger).

What Can Go Wrong

The efficient distribution of oxygen may be disturbed in two ways:

•The system (heart, arteries, veins etc.) can develop a fault.

•The blood is unable to carry enough oxygen for the needs of the tissue cells.

System Failures

The heart (pump) can be damaged. Heart tissue is muscle which responds to electrical impulses from the brain to contract or relax systematically. Sometimes this controlling system does not carry the impulses in a coordinated way. The heart beat may become irregular or even fail altogether.

In modern surgery a mechanical device (pacemaker) may be implanted to produce the regular electrical impulses to cause the heart to beat at a regular rate. These electrical impulses and their synchronisation with the heart’s pulse rate can be measured, by an electrocardiogram (ECG). An ECG test is incorporated in aircrew medical examinations.

The heart muscles require oxygen to continue working. This oxygen is carried to the heart by the coronary arteries. If a narrowing of these vessels should occur then insufficient blood may reach the heart muscle. This lack of oxygen, particularly when the heart is beating faster due to exercise or stress, will give rise to the symptoms of angina, with pain in the chest and sometimes the arms.

If the blood supply is cut off completely then a portion of the heart muscle may die (an infarct). The dead tissue is unable to carry the electrical impulses and the heart beat may become irregular or even fail completely (a heart attack).

Heart Attack (Myocardial Infarction).

Angina is often a precursor to the development of a heart attack. Approximately half of those who have a myocardial infarction die immediately. A proportion go on to develop an associated abnormality of the heart rhythm which can completely interrupt the co-ordinated muscular contractions of the heart (cardiac arrest).

The most common of these disturbances is called ventricular fibrillation. If this can be treated promptly with an application of DC shock via a Defibrillator, then the heart may revert to

The Circulation System 2

System Circulation The 2

its normal rhythm and the patient may survive. If the patient’s essential circulation can be supported by cardiac massage and assisted ventilation, he/she may survive while waiting for a defibrillator to be available. Without treatment cardiac arrest is fatal within 4 minutes.

Those who survive the first 24 hours post myocardial infarction will have a good chance of recovery however the retrieval of a flying licence will not be possible without extensive investigation and - in any case - a restriction to multi-crew operations will always be imposed.

Factors Predisposing to Heart Attack

The factors predisposing to a heart attack, in order of importance, are:

•Family History (heredity).

•Age.

•Previous history of cardiovascular problems.

•Raised blood pressure (hypertension).

•Smoking.

•Raised blood cholesterol.

•Lack of exercise.

•Diabetes.

Other factors such as stress, obesity, alcohol and certain dietary considerations are less clearly understood. It is noteworthy that coronary disease is responsible for 70% of pilot deaths during their careers.

Incapacitation in Flight

The dramatic and sudden incapacitation of a pilot during flight is uncommon and very rarely the cause of an accident. An aircraft accident at Staines was one of the very few major accidents in civil aviation due to the pilot suffering a heart attack. Rigorous medical selection and periodic health checks minimize the risk of total incapacitation due to heart disease, epilepsy etc. As the pilot grows older the frequency of medical checks increases. ECG (electrocardiogram) and EEG (electroencephalogram) recordings are used more and more to spot those at risk.

Insufficient Oxygen Carried

The cells of the various tissues may be deprived of the oxygen they need because of:

•Insufficient haemoglobin or red blood cells (anaemia). This can be primarily caused by the breakdown of the production process of haemoglobin in the bone marrow or by excessive bleeding.

•Insufficient pressure of oxygen in the air. The pressure of oxygen in the air (partial pressure) reduces with altitude and people who live at high altitude for a prolonged period produce more red blood cells than those who live at sea level. In other cases it will be necessary to add oxygen to the air breathed. This topic is treated fully in the next chapter.

•A lack of iron.