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750

SECTION 6

Pancreas

 

 

 

 

Postoperative Tests

 

Thoracoscopic Splanchnicectomy

Surveillance in an intermediate care unit with oxygen saturation monitoring

Routine chest radiograph to exclude residual pneumothorax

Local Postoperative Complications

Intraoperative Splanchnicectomy

Short term:

Intra-arterial injection of neurolytic agent – this can be prevented by aspirating the syringe containing the neurolytic agent before injecting

Retroperitoneal bleeding – unusual, minimized by applying topical pressure after instillation of neurolytic agent

Transient orthostatic hypotension – unusual, lasts only 1–2days

Very rare, anecdotal case reports of paraplegia secondary to intrathecal injection of neurolytic agent – this is preventable with careful technique

Long term:

Recurrent pain

Thoracoscopic Splanchnicectomy

Short term:

Pulmonary: pneumothorax, hemothorax, and hemo-pneumothorax – treat by closed intercostal chest drainage. Less common is chylothorax, requiring ligation of the thoracic duct.

Transient ileus – managed conservatively.

Inadvertent injury or transection of sympathetic chain may predispose to retrograde ejaculation.

Long term:

Recurrence of pain

Denervation: Pain Management

751

 

 

Tricks of the Senior Surgeon

Intraoperative splanchnicectomy:

Use a 20-gauge spinal needle (longer than a regular needle).

Use of a smaller volume syringe allows the surgeon to hold the needle/syringe in one hand.

Do not disrupt the peritoneum overlying the retroperitoneum in the region of the celiac plexus.

Two minutes of topical pressure will prevent hematomas.

Thoracoscopic splanchnicectomy:

Meticulous positioning of the ports aids visibility of the entire sympathetic chain.

Total collapse of the lung is unnecessary; an 8-cm water pressure pneumothorax is also usually adequate to identify the splanchnic nerves.

The proximal contribution to the GSN is identified by tracing the sympathetic chain distally as it courses over the necks of the proximal ribs.

Gentle traction on the sympathetic chain brings the splanchnic branches into profile.

Troublesome bleeding from an intercostal vein can be controlled with pressure, cautery, or clip.

Accurate placement of ports in the intercostal spaces avoids postoperative intercostal neuralgia.

Enteric Ductal Drainage for Chronic Pancreatitis

William H. Nealon

Introduction

The concept of draining an apparently obstructed main pancreatic duct was first addressed by opening either the proximal end of the pancreatic duct at the ampulla by doing a sphincterotomy or at the distal end of the pancreatic duct by removing the tail (Duval procedure). Puestow is credited with the concept of a longitudinal incision along the main pancreatic duct through the body and the head of the pancreas. This procedure was first described as a modification of a Duval procedure and therefore included resection of the pancreatic tail. Partington and Rochelle determined that a tail resection was unnecessary and carried out only a side-to-side lateral pancreaticojejunostomy. The principle of the procedure is to decompress an apparently obstructed main pancreatic duct (and maybe to also decompress the pancreatic parenchyma – the pancreatic compartment syndrome suggested by Reber). This assumption is based on the fact that the pancreatic duct is markedly dilated, suggesting a restriction to flow.

Indications and Contraindications

Indications

Chronic persistent pain

 

To prevent episodes of acute exacerbations in chronic pancreatitis

 

To facilitate resolution of symptomatic pancreatic pseudocyst

 

To prevent further loss of pancreatic exocrine and endocrine function

 

 

“Small duct” (<5mm) chronic pancreatitis

Contraindications

 

Extrahepatic venous obstruction, because of the risk of hemorrhage

 

Suspicion of malignancy

 

Advanced cirrhosis

754

SECTION 6

Pancreas

 

 

 

Preoperative Investigations and Preparation for Procedure

 

History:

History of chronic, unremitting epigastric abdominal pain

 

 

or acute exacerbations of typical pancreatic pain, history

 

 

of ethanol abuse or other possible causes of chronic pancre-

 

 

atitis

 

Clinical evaluation:

Establish presence or absence of narcotic usage and require-

 

 

ment (if narcotic addicted, entertain the concept of postopera-

 

 

tive detoxification), frequency of hospitalizations, nutritional

 

 

status, pancreatic functional status (endocrine and exocrine),

 

 

ASA risk status

 

Laboratory tests:

Serum amylase and/or lipase, albumin, alkaline phosphatase,

 

 

GGT, bilirubin coagulation parameters, CA 19–9, glucose

 

Imaging:

CT or MRI/ MRCP, ERCP if indicated

 

Preparation for surgery:

Maximize endocrine status (insulin), maximize exocrine

status (enzyme replacement), bowel preparation if necessary, perioperative prophylactic antibiotics

Enteric Ductal Drainage for Chronic Pancreatitis

755

 

 

 

Procedure: Lateral Pancreaticojejunostomy

 

(Modified Puestow Procedure)

 

 

STEP 1

Exposure and exploration are facilitated by insertion of a retractor (Thompson)

 

First, the lesser sac is entered by separating the attachments between the gastrocolic

 

 

omentum and the transverse colon.

 

Any “congenital” or acquired adhesions between the posterior surface of the stomach

 

and the anterior surface of the pancreas are transected widely, exposing the anterior

 

surface of the pancreas, including the head of the pancreas – take care to identify and

 

exclude the right gastroepiploic artery and vein, which are situated between the head

 

of the pancreas and the pylorus.

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SECTION 6

Pancreas

 

 

 

STEP 2

Mobilize the inferior border of the body of the pancreas

 

 

 

 

Identify and avoid the inferior mesenteric vein to the left of the spine.

Extend the dissection from the body toward the head of the pancreas. This facilitates bimanual examination and palpation of the anterior surface of the gland.

Place a broad curved retractor beneath the posterior wall of the stomach and retract superiorly.

Palpate and determine the location of the main pancreatic duct.

Enteric Ductal Drainage for Chronic Pancreatitis

757

 

 

STEP 3

The pancreas should be easily appreciated because of its hard, fibrotic texture.

The dilated main pancreatic duct feels a bit like a large vein on the arm with a ballotable texture and a definite “trough.”

The superior and inferior borders of this softer area feel like a canyon or a cliff and this represents the fibrotic pancreas on both sides.

Once the palpation is conclusive, a 22-gauge needle is passed through the anterior surface of the pancreas and into the pancreatic duct; on removing the needle, you should see clear fluid return, confirming that the main pancreatic duct has been accessed. The purpose of this maneuver is to avoid incising into the splenic vein or another structure mistaken for the main pancreatic duct.

Once pancreatic juice is determined, then electrocautery is utilized to incise the anterior surface of the body of the pancreas into the pancreatic duct parallel and adjacent to the needle, which is left in the pancreatic duct as a guide.

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SECTION 6

Pancreas

 

 

 

STEP 4

A right angle clamp will facilitate using the electric cautery to open widely the duct out to the tail of the pancreas laterally and toward the head of the pancreas. As you reach the genu of the main pancreatic duct it is important to extend the incision through the genu and toward the ampulla. This maneuver requires not only turning the incision inferiorly but also considerably increasing the depth of incision through the parenchyma of the pancreas in the head of the gland because the duct goes more posteriorly. This area also has a rich blood supply, and some amount of hemorrhage may be encountered during this incision. Success rates are thought to depend on in great part on an adequate drainage into the head of the pancreas in this manner. There appears to be less significance to the extent of drainage into the tail of the pancreas except in patients who have more localized disease in the tail of the pancreas.

Once adequate space is established, a Seurat clamp may be utilized. All stones encountered should be removed from the duct; any secondary ductular stones should also be removed.

Enteric Ductal Drainage for Chronic Pancreatitis

759

 

 

 

STEP 5

Roux-en-Y jejunal preparation

 

 

 

 

An area is chosen approximately 15cm distal to the ligament of Treitz in a position which will facilitate easy performance of the jejunojejunostomy. The mesenteric attachments are divided between clamps to mobilize the Roux limb. A GIA stapling device is utilized to divide the jejunum at this site.

The avascular area is then chosen in the left transverse mesocolon. A window is created through which the distal divided end of jejunum may be brought. It is important to avoid undue tension at the mesentery; at times, it is necessary to divide the truncal branches of the jejunal mesenteric vessels below the arcade to permit a flexible limb. The divided end of jejunum is aligned toward the head of the pancreas, and a side- to-side approach is established.

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SECTION 6

Pancreas

 

 

 

STEP 6

Pancreaticojejunostomy

 

 

 

 

The anastomosis is performed using a single layer of nonabsorbable suture. We use two, separate, 3-0 silk sutures. The posterior suture line is placed first before opening the jejunum (A-1.1). It is important to make smaller advances in the jejunum than is made in the open pancreatic duct. The first suture is placed just at the corner of the ductal incision in the tail of the pancreas and each suture is placed progressionally toward the head of the pancreas (A-1.2). The advance on the jejunum may be no more than 3mm, whereas the advance on the pancreatic duct may be 6mm. The depth of insertion of the needle into the pancreatic body into the duct depends upon the pancreas. In a relatively thin parenchyma, the sutures are placed into the duct itself. On occasion a very thick pancreatic parenchyma is better managed by placing sutures into the capsule of the pancreas, but they may be tied above the epithelium of the main pancreatic duct. Sutures are not tied until each suture has been placed over to the corner toward the head of the pancreas.

At this point, the limb of jejunum is lowered and placed in its position for anastomosis, and all sutures are tied.

An incision is then made in the jejunal limb to match the size of the pancreatic duct incision. The reason for placing the sutures more closely on the jejunum is the fact that once the jejunum is opened it typically dilates, and you may be left with a very poor match in sizes for your anterior suture line.

A-1.1

A-1.2