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I.Overview

II.Anatomy

III. Physiology

Autono

mic

Nervous

System

1

The Autonomic Nervous System

Regulate activity of smooth muscle, cardiac muscle & certain glands

Structures involved

1.general visceral afferent neurons

2.general visceral efferent neurons

3.integration center within the brain

Receives input from limbic system and other regions of the cerebrum

2

Autonomic versus Somatic NS

Somatic nervous system

consciously perceived sensations

excitation of skeletal muscle

one neuron connects CNS to organ

Autonomic nervous system

unconsciously perceived visceral sensations

involuntary inhibition or excitation of smooth muscle, cardiac muscle or glandular secretion

two neurons needed to connect CNS to organ

preganglionic and postganglionic neurons

3

 

Autonomic versus Somatic NS

Autonomic NS pathway is a 2 neuron pathway

Somatic NS pathway only contains one neuron.

4

Basic Anatomy of ANS

Preganglionic neuron

cell body in brain or spinal cord

axon is myelinated type B fiber that extends to autonomic ganglion

Postganglionic neuron

cell body lies outside the CNS in an autonomic ganglion

axon is unmyelinated type C fiber that terminates in a visceral

effector

5

 

Divisions of the ANS

2 major divisions

1.parasympathetic

2.sympathetic

Dual innervation

one speeds up organ

one slows down organ

Sympathetic NS increases heart rate

Parasympathetic NS decreases heart rate

6

I.Overview

II.Anatomy

A.Neurotransmitter

III. Physiology

Autono

mic

Nervous

System

7

Sources of Dual Innervation

1.Sympathetic (thoracolumbar) division

preganglionic cell bodies in thoracic and first 2 lumbar segments of spinal cord

2.Parasympathetic (craniosacral) division

preganglionic cell bodies in nuclei of 4

cranial nerves and the

 

sacral spinal cord

8

 

ANS Neurotransmitters

Classified as either cholinergic or adrenergic neurons based upon the neurotransmitter released

Adrenergic

Cholinergic

19

Parasympathetic

Cholinergic neurons release acetylcholine from preganglionic neurons & from parasympathetic postganglionic neurons

Action: Excites or inhibits depending upon receptor type and organ involved

Receptor:

Nicotinic receptors are found on dendrites & cell bodies of autonomic NS cells and at NMJ

Muscarinic receptors are found on plasma membranes of all parasympathetic effectors

20

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