BIS Titration SimulatOR / Xtras / drugs / NO2X.V0.DRG

* The first 7 lines in this file are for comments
*
* DRUG = Nitrite Ion
* Drug types: NARCOTIC=1, NMBA=2, PRESSOR=3, DRG_SEDATIVE=4,
* ANESTHETIC=5, DRG_TRANQ=6 , DRG_INOTROPE=7 ,
* DRG_DIALATOR=8
*
%
% Nitrite
% Uses: Antidote to cyanide
% Dose: (iv) 300 mg (30 mg/ml in 10 ml syringe)
% Site of clearance: blood, liver
% Interaction/toxicity: induces hypotension, converts HbO2 to
% metHb; both decrease O2 supply to vital organs.
%
% **This ampoule is a special mixture for reseach and
% experimentation -- it contains only NO2-, no other ions.
%
drg_name = NO2
drg_max_conc = 10.0
drg_type = 11
drg_dhrtrt = 0.0
drg_dcontr = 0.0
drg_dres08 = -1.0
drg_dres09 = -1.0
drg_dres10 = -1.0
drg_dres11 = 0.0
drg_dres13 = 0.0
drg_dres15 = -0.5
drg_dvncom = 0.4
drg_dbrslp = 0.0
drg_pco2stpt = 0.0
drg_pco2spsl = 0.0
drg_drespr = 0.0
drg_metrate = 0.95
drg_MAC = 0.0002
drg_ic50 = 0.0002
drg_curve = 4
xtract_kidny = 1.0
xtract_liver = 0.8
lambda_b = 1.0
lambda_7 = 11.0
lambda_8 = 1.5
lambda_9 = 1.0
lambda_15 = 1.0
lambda_10 = 1.0
lambda_11 = 1.2
lambda_12 = 1.4
lambda_13 = 1.4
diffk_7 = 1.0
diffk_8 = 1.0
diffk_9 = 1.0
diffk_15 = 1.0
diffk_10 = 1.0
diffk_11 = 1.0
diffk_12 = 1.0
diffk_13 = 1.0
Binding = 0.005
UnitCost = 1.0
DP_NMBlock = 0.0
NDP_NMBlock = 0.0
ANES_effect = 0.0
ANLGS_effect = 0.0
ACh_inhibit = 0.0
PVC_level_effect = 0.0