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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_4012_Библиотеки_им_академика_М_И_Перельмана
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INDEX
A
acidosis, 124, 131
adaptation, 1, 8, 19, 109, 110, 147
adhesion, 25, 30, 58, 69
adjustment, 56, 80, 81, 85, 105, 106, 107,
108, 126, 130
adults, 68, 69, 84, 85, 93, 130, 143, 153
adventitia, 13, 25
adverse effects, 57
aerobic exercise, 138, 147, 151, 154
age, 7, 9, 10, 11, 19, 21, 41, 43, 44, 46, 47,
51, 54, 55, 56, 60, 61, 62, 65, 67, 76, 77,
79, 80, 81, 84, 85, 87, 89, 99, 103, 105,
108, 111, 122, 125, 126, 127, 128, 129,
138, 139, 142, 143, 144, 146, 151, 153
air temperature, 155
airflow obstruction, 56, 60, 71
airways, 62
albumin, 98, 102, 106, 131
albumin excretion rate, 98, 102, 106
albuminuria, 85, 98, 99, 102, 103, 105, 109,
112
alcohol consumption, 139
aldosterone, 49
alkaline phosphatase, 80, 81
alters, 25, 59, 88
alveoli, 62
amino acid, 83
angina, 38, 122
angiogenesis, 26
angioplasty, 122
angiotensin II, 73
angiotensin receptor blockers, 73
ANOVA, 47, 101, 102, 105, 106, 108, 142
antibody, 86, 96
anticoagulant, 122
antihypertensive agents, 43
aorta, 45, 84
aortic stenosis, 82, 84, 91
aortic valve, 78, 80, 82, 89, 91
apoptosis, 30, 62, 83
arterial hypertension, 3, 26, 27, 28, 29, 30,
31, 32, 33, 34, 35, 37, 38, 39, 41, 42, 43,
48, 49, 99, 113, 133
arterial Stiffness, 1, 12, 13, 14, 19, 21, 30,
32, 34, 41, 42, 44, 45, 53, 54, 55, 56, 57,
67, 68, 70, 71, 72, 73, 75, 77, 78, 79, 81,
83, 88, 97, 120, 124, 129, 132, 133, 135,
137, 138, 147, 150, 151, 154
arterial stiffness index, 15, 82, 97, 98, 99,
108, 111, 112, 113, 114, 116
arteries, 3, 4, 5, 8, 12, 13, 20, 31, 35, 42, 46,
47, 48, 49, 50, 51, 54, 57, 59, 60, 66, 76,
77, 82, 83, 84, 87, 98, 106, 112, 120,
137, 138, 147
arterioles, 4, 13, 25
arteriosclerosis, 62, 76, 77, 135
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158
assess, 1, 4, 14, 24, 59, 86
assessment, 2, 3, 24, 26, 31, 35, 37, 38, 39,
51, 55, 68, 71, 79, 111, 124, 139
asthma, 70
asymptomatic, 25, 45
Αthens, 119
atherosclerosis, 45, 57, 63, 69, 82, 84, 87,
90, 91, 92, 95, 114, 120, 133, 135
atherosclerotic plaque, 82, 91
B
baroreceptor, 137, 138, 144, 145, 146, 148,
149, 150, 152
baroreceptor reflex sensitivity, 138, 144,
145, 146, 148, 149, 150
basement membrane, 58
basic research, 22
behaviors, 69
beneficial effect, 56
beta-2 agonist, 72
bicarbonate, 122, 123, 126, 128
bilateral, 48
biological markers, 65
biomarkers, 93, 95
biopsy, 79, 90
birth weight, 101, 102, 103, 106
blood, 2, 3, 4, 5, 7, 13, 15, 25, 43, 50, 51,
56, 60, 61, 64, 65, 67, 71, 82, 89, 97, 98,
99, 107, 108, 109, 112, 113, 114, 116,
117, 122, 123, 124, 125, 134, 137, 138,
139, 140, 141, 142, 143, 144, 145, 146,
147, 149, 150, 152, 153, 155
blood flow, 51, 122, 147, 153
blood pressure, 2, 3, 43, 50, 56, 60, 61, 64,
65, 71, 82, 97, 98, 99, 107, 108, 109,
112, 113, 114, 116, 117, 125, 134, 137,
138, 139, 140, 141, 142, 143, 144, 145,
146, 147, 149, 150, 152, 153, 155
body mass index (BMI), 46, 55, 85, 93, 100,
103, 111, 124, 126, 128
body weight, 122, 124
brachial, 42, 43, 46, 47, 48, 49, 80, 82, 130,
134, 141
brain, 57, 133
branching, 25
breakdown, 14, 20
breast cancer, 116
bronchitis, 56
Bulgaria, 41
C
calcification, 56, 58, 62, 75, 76, 77, 78, 79,
80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90,
91, 92, 93, 94, 95, 131, 132
calcinosis, 121
calcitonin, 78
calcium, 21, 32, 33, 77, 78, 82, 88, 91, 121,
122, 133
calcium channel blocker, 21, 32, 33, 43, 122
caliber, 3
capillary, 7, 33
cardiac catheterization, 31, 82
cardiac output, 2, 7
cardiovagal baroreceptor, 137, 138, 145
cardiovascular disease, 24, 53, 54, 56, 66,
72, 76, 77, 92, 109, 120, 122, 129, 132,
137, 138
cardiovascular morbidity, 41, 42, 48, 53, 54,
75, 86, 119, 121
cardiovascular risk, 41, 42, 43, 53, 54, 55,
57, 62, 67, 71, 73, 75, 77, 84, 87, 152,
153
cardiovascular system, 83, 147
carotid arteries, 48, 137, 138
carotid-femoral PWV, 42, 55, 60, 85, 120
cellular signaling pathway, 12
challenges, 8, 96
channel blocker, 43
Chicago, 125
children, 85, 94
cholesterol, 64, 71, 82, 140, 142
chronic heart failure, 28
chronic hypoxia, 9, 33
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159
chronic kidney disease (CKD), 51, 75, 76,
87, 90, 92, 93, 94, 95, 132
Chronic Obstructive Pulmonary Disease,
23, 37, 53, 54, 66, 67, 68, 69, 70, 71, 72,
73
chronic renal failure, 133, 135
circadian rhythm, 98, 109, 112
circulation, 2, 3, 8, 27, 31, 59, 80, 110
CIS, 124
CKD, 77, 79, 80, 81, 82, 84, 85, 86, 89, 95,
132
classification, 21
clinical application, 30, 50, 134
clinical assessment, 129
clinical trials, 35
cobalamin, 116
coding, 66
coefficient of variation, 9
cognitive function, 77
coherence, 35, 37, 39
collagen, 5, 13, 54, 58, 60, 62
combination therapy, 35
common carotid, 42, 46, 47, 48, 80
complex interactions, 86
compliance, 3, 4, 5, 6, 13, 16, 17, 19, 27, 28,
29, 31, 33, 43, 45, 47, 49, 60, 61, 64, 76,
134, 138, 147, 152, 154
complications, 56, 57
composition, 20
computed tomography, 77, 80, 82, 84, 85
computer, 60, 141
concentrations, 59, 81, 82, 84, 85, 88, 91,
120, 124, 126, 128, 129, 130, 131, 133,
142
confounders, 81, 120, 125, 126, 127, 128,
130, 131
confounding variables, 126
congenital heart disease, 25, 30, 33
connective tissue, 19, 54, 58, 61, 62, 65
consensus, 30, 42, 44, 46, 50, 66
consumption, 139
contingency, 102
contour, 80, 82
control group, 9, 18, 110
controversial, 121
COPD, 23, 29, 53, 54, 55, 56, 57, 58, 59,
60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70,
71, 72, 73
coronary arteries, 82
coronary artery disease, 47, 50, 62, 72, 122
coronary disease, 62, 119, 120, 122, 125,
126, 128, 130, 131, 132
coronary heart disease, 64, 72
correlation, 8, 16, 28, 42, 45, 46, 47, 48, 56,
60, 65, 77, 81, 82, 84, 85, 94, 131, 142,
143, 144, 145
correlation analysis, 142, 143, 144, 145
correlation coefficient, 142
correlations, 79, 81, 129, 142
cortical bone, 77
corticosteroids, 63, 83
Cox regression, 81, 119, 125
Croatia, 153
cross-sectional study, 62, 77, 80, 89, 90
CRP, 58, 59, 60, 131
crystal growth, 81
cycling, 139, 154
cyclosporine, 37
cystic fibrosis, 37
cytokines, 58, 131
D
DBP, 124, 125, 140, 141, 142, 144, 146
decay, 5, 6
deficiency, 37
deformation, 13
degradation, 13, 14, 54, 58, 60, 62
demographic characteristics, 48
dendritic cell, 83
Denmark, 97, 114, 115
dependent variable, 102
deposition, 13, 25, 76, 91
destruction, 65
destructive process, 59
detection, 2, 9, 22, 30, 80, 98
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160
developmental factors, 55
diabetes, 41, 43, 51, 55, 67, 76, 78, 82, 84,
85, 91, 93, 97, 98, 99, 100, 103, 104,
105, 108, 113, 114, 115, 116, 117, 125,
126, 127, 128, 134
diabetes mellitus, 55, 76, 97, 99, 104, 114,
116, 117, 125, 126, 127, 128, 134
diabetic nephropathy, 123
diabetic patients, 109
diagnostic criteria, 4
dialysis, 80, 81, 84, 91, 93, 94, 95, 103, 119,
120, 121, 122, 123, 124, 125, 126, 127,
128, 129, 130, 131, 132, 133, 134
diastole, 5, 47, 102, 105
diastolic blood pressure, 44, 46, 124, 125,
129, 131, 140, 144
diastolic pressure, 6, 57
Dickkopf-1, 75, 76, 89, 90, 91, 95
diet, 88
dietary habits, 151
dilation, 19
disease progression, 13, 21, 25
diseases, 30, 53, 54, 64, 89, 96
disorder, 95, 130, 155
displacement, 7
distribution, 5, 35, 47, 102, 125, 134
DKK-1, 75, 78, 81, 82, 86
DNA, 62
dogs, 26
DOI, 155
drug delivery, 33
drug targets, 21
drug therapy, 59, 112
drugs, 14, 49, 65, 77, 122
dyslipidemia, 56, 60, 62, 125, 126
E
ECG, 140, 141
ECM, 13, 14, 20, 25, 26
effectiveness of therapy, 42, 49
elastic modulus, 2, 14, 15, 16, 17, 19
elastin, 5, 13, 20, 54, 58, 60, 61, 62
emphysema, 37, 54, 56, 60, 61, 62, 64, 67,
70, 71, 72, 73
encoding, 29
endothelial cells, 25, 30, 32, 62, 83
endothelial dysfunction, 25, 61, 120
endothelium, 25, 78, 152
end-stage renal disease, 39, 79, 90, 93, 129,
133, 134
endurance, 152, 153
enlargement, 62
environment, 14
environmental factors, 61
enzyme, 43, 60, 73, 124
enzyme inhibitors, 73
EPA, 70
epidemiologic, 76, 77
epidemiology, 36
equipment, 101
ERS, 27
ESRD, 79, 80, 84, 121
estrogen, 88, 109
Europe, 43
evidence, 2, 7, 12, 22, 23, 25, 42, 43, 45, 47,
51, 54, 76, 77, 78, 83, 98
exclusion, 121
excretion, 78, 79, 88, 98, 102, 106, 129
exercise, 3, 7, 9, 11, 12, 23, 24, 25, 27, 29,
30, 31, 64, 65, 137, 138, 139, 140, 142,
143, 144, 145, 146, 147, 148, 149, 150,
151, 152, 153
exertion, 142, 144
expertise, 24
exposure, 116
extracellular matrix, 13, 60
F
false positive, 12
fasting, 65, 123, 142
fat, 133
femoral arteries, 42, 46, 47, 48, 49
fetal growth, 117
fetus, 98
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161
fiber, 5, 14, 62, 70
fibroblast growth factor, 78, 88
fibroblasts, 13, 20, 25
fibrosis, 13, 20, 25, 35, 37, 39, 58, 61, 64
filtration, 79, 84, 113
flexor, 146
flow curves, 30
fluid, 5, 6, 35, 71, 131, 133, 134
fluid management, 133
formation, 76, 78, 86, 120
formula, 4, 5, 8, 122, 124, 125
fractures, 77, 88
France, 29, 124
G
gene expression, 88
genes, 88, 89, 135
genetic predisposition, 61
Germany, 124
gestational age, 102, 103
gestational diabetes, 99, 113, 117
glomerulonephritis, 123
glucose, 65, 142
glycoproteins, 13, 78
grading, 93
graft dysfunction, 36
Greece, 75, 119
growth, 61, 113
guidelines, 43, 45
H
health, 1, 5, 8, 28, 77, 86
heart disease, 23, 139
heart failure, 2, 122
heart rate (HR) , 61, 71, 125, 138, 139, 144,
153
hemodialysis, 77, 80, 81, 85, 87, 89, 90, 91,
93, 94, 95, 120, 122, 130, 133, 134
hemoglobin, 124, 142
high blood pressure, 122
high density lipoprotein, 123
history, 22, 24, 56, 71, 116, 122
homeostasis, 76, 88, 124
hormone, 78, 88, 135
hospitalization, 24, 58
hydrolysis, 80
hydroxyapatite, 81
hyperinflation, 59
hyperplasia, 25
hypertension, 1, 2, 3, 11, 12, 19, 22, 26, 27,
28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38,
39, 41, 42, 43, 48, 49, 50, 51, 62, 64, 66,
69, 70, 71, 72, 73, 77, 98, 99, 101, 102,
103, 109, 110, 111, 112, 113, 114, 117,
125, 126, 127, 128, 129, 131, 132, 133,
134, 152, 153
hypertrophy, 13, 19, 20, 25, 44, 57, 99, 120,
129
hypothesis, 8, 55, 80, 137, 138
hypoxemia, 56, 60
hypoxia, 59, 60, 64, 65
hysterectomy, 117
I
identification, 24, 26, 43
idiopathic, 7, 14, 19, 22, 29, 30, 32
IL-17, 83
immune system, 83
in vitro, 9, 80
in vivo, 5, 33
incidence, 43, 68, 103
indirect effect, 37
indirect measure, 99
individuals, 43, 45, 56, 61, 69, 77, 99, 102,
138, 139, 146, 147, 151, 153, 155
inertia, 3
infection, 36, 37
inflammation, 14, 20, 25, 39, 54, 56, 58, 59,
60, 62, 63, 64, 65, 66, 69, 70, 78, 83,
120, 121, 131, 132, 133, 135
inflammatory cells, 13, 58
inflammatory disease, 76, 87
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162
inflammatory mediators, 58, 59
informed consent, 99, 123, 139
inhibitor, 78, 81, 89, 95, 154
inhibitors of angiotensin-converting
enzyme, 43
initiation, 25, 85, 122
insulin, 113, 124, 131, 133, 142
insulin resistance, 124, 131, 133
integrin, 14, 33
integrins, 14
interobserver variation, 42
interstitial lung disease, 23
intervention, 22, 26, 56
intima, 25, 58, 132
intravascular ultrasound, 2, 15, 26, 31
i-PTH, 120, 124, 126, 128, 129, 131
ischaemic heart disease, 129
ischemia, 57
issues, 30, 33, 50, 110
Italy, 41, 46
L
laminar, 25
LDL, 64, 100, 123, 124, 126, 127, 128, 131,
140
lead, 21, 43, 83, 140, 147
left ventricle, 3
lesions, 2, 25
ligand, 78, 82, 91, 92
lipid peroxidation, 59
lipoproteins, 123
liquids, 132
local PWV, 42, 45, 46, 49
longitudinal study, 57, 88, 133
low risk, 42, 43, 48, 77
low-density lipoprotein, 78
lumbar spine, 77
lumen, 15, 16, 22
lung disease, 28, 69, 71
lung function, 55, 58, 65, 66, 67, 69
lung transplantation, 23, 28, 36, 37, 38
Luo, 50
M
macrophages, 20
magnetic resonance, 15, 27, 29, 32
magnetic resonance imaging (MRI), 15, 29
majority, 22, 43, 44, 85, 98, 110
malignancy, 122
malnutrition, 133
management, 29, 36, 43, 49, 66, 87
Marfan syndrome, 70
mass, 3, 124, 126, 128, 130, 140, 146, 148,
149, 150
matrix, 14, 58, 60, 71, 94
matrix metalloproteinase, 14, 58
MBP, 114, 124, 125, 126, 128, 141, 146
mean arterial pressure, 77
mechanical properties, 51
mechanical stress, 14, 78
median, 21, 22, 81, 82, 119, 121, 125, 126,
127, 130
medical, 110, 115, 116
medication, 122, 146, 148, 149, 150
medicine, 139
mellitus, 55, 76, 97, 99, 104, 114, 116, 117,
125, 126, 127, 128, 134
membrane permeability, 133
menopause, 77
mesenchymal stem cells, 83
meta-analysis, 67, 69, 114, 152
Metabolic, 116, 124
metabolic acidosis, 120, 131, 132, 133
metabolic syndrome, 59
metabolism, 77, 78, 83, 84, 86, 88, 89, 91
metalloproteinase, 70
metformin, 117
methodology, 98, 110, 111, 112, 113, 116,
117
microcirculation, 5, 35
migration, 58
mineralization, 78, 80, 83, 86
Ministry of Education, 34
MMP, 14, 58, 60, 70
MMP-2, 14, 60, 70
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163
MMP-3, 14
MMP-9, 14, 60, 70
models, 2, 48, 62, 86
modifications, 54, 141, 151
modulus, 2, 14, 15, 16, 17, 19
molecular weight, 122
molecules, 25, 58, 69, 76
morbidity, 66, 73, 76, 77, 99, 110, 120
mortality, 2, 4, 16, 21, 22, 24, 28, 30, 32,
36, 41, 42, 48, 53, 54, 62, 64, 66, 68, 72,
73, 75, 76, 77, 81, 82, 85, 86, 88, 90, 94,
95, 112, 113, 119, 120, 121, 125, 126,
127, 129, 130, 131, 132, 134, 152
mortality rate, 76, 119, 121, 125, 126, 130,
131, 132
mortality risk, 66, 95
mRNA, 79, 80, 88, 89
multiple regression, 79
multiple regression analyses, 79
myocardial infarction, 2, 120, 122
N
Na
+
, 123
nanoparticles, 95
National Health and Nutrition Examination
Survey (NHANES), 67, 69
nephropathy, 98, 99, 109
nerve, 51, 71, 147
neurohormonal, 54, 65
neutrophils, 58, 69
nitric oxide, 39, 59, 63, 65, 153, 154, 155
nitric oxide synthase, 63, 154
nocturnal blood pressure, 98, 109, 113
Norway, 114
nutrients, 151
O
obesity, 41, 43, 62, 77
obstruction, 35, 55, 76
occlusion, 5, 27
oedema, 122
OPG, 78, 82, 83, 84, 85, 86
organ, 36, 37, 42, 43, 44, 48, 99, 113
orthostatic hypotension, 122
osteocyte, 90
osteogenetic, 83
osteoporosis, 55, 62, 65, 67, 76, 77, 84, 92,
96
Ostoprotegerin, 75
outpatient, 117
overlap, 109
ox, 124, 131
oxidative stress, 39, 54, 58, 59, 60, 62, 65,
70, 72, 121
oxygen, 11, 59, 61, 64, 71, 129, 147, 152
oxygen consumption, 129, 152
oxyhemoglobin, 61
P
parallel, 45, 79, 85
parathyroid, 78
parathyroid hormone, 78
participants, 61, 110, 121, 139
pathogenesis, 54, 58, 69, 79, 87
pathology, 33
pathophysiological, 129
pathophysiology, 61, 70, 77, 83, 86, 95
pathway, 54, 66, 75, 76, 77, 78, 86, 89
PCR, 129
peptide, 20, 61, 133
perfusion, 57, 129
peripheral vascular disease, 84
PET, 59, 70
pH, 123
pharmaceutical, 86
pharmacokinetics, 37
pharmacological treatment, 56
phenotype, 25, 26, 56, 59, 90
phosphate, 79, 87, 122
phosphorus, 88, 95
physical activity, 65, 77, 139, 151, 153, 155
physical exercise, 65
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164
physicians, 35
physiology, 83, 88
pilot study, 29, 70
placebo, 63
placenta, 78
plaque, 45, 76, 91, 120
plasma levels, 59, 142
platelets, 78
PM, 33, 71
pollution, 61
population, 10, 43, 46, 47, 53, 54, 56, 57,
66, 68, 72, 77, 79, 81, 84, 98, 109, 119,
121, 126, 129, 132
positive correlation, 46, 59, 79
positive feedback, 20, 21
post-transplant, 84
predictor, 1, 2, 4, 12, 34, 41, 42, 48, 54, 62,
67, 69, 75, 77, 81, 84, 90, 93, 112, 120,
129, 130, 132, 138, 143, 150
preeclampsia, 98, 99, 102, 103, 109, 110,
111, 116
pregnancy, 97, 98, 99, 100, 101, 102, 103,
104, 105, 106, 109, 110, 112, 113, 114,
116, 117
premature vascular ageing, 54, 55
pressure gradient, 4
preterm delivery, 117
prevention, 37, 71, 72, 132
primary pulmonary hypertension, 27, 29, 31
prognosis, 4, 69, 109
pro-inflammatory, 20
proliferation, 20, 30, 58, 59, 64
prophylaxis, 36
prostaglandin, 83
proteasome, 135
proteins, 13, 14, 69, 77, 78
proteoglycans, 13
proteolysis, 135
pulmonary artery, 2, 5, 8, 10, 17, 18, 20, 27,
28, 29, 30, 31, 32, 33, 65
pulmonary artery pressure, 28, 30, 32, 33
pulmonary circulation, 2, 4, 5, 6, 8, 9, 12,
19, 22, 28, 31, 35
pulmonary diseases, 63
pulmonary embolism, 37
pulmonary hypertension, 1, 2, 22, 26, 27,
28, 29, 30, 31, 32, 33, 34, 35, 37, 64, 73
pulmonary rehabilitation, 65, 70, 73
pulmonary vascular resistance, 3, 10, 17, 29
pulse pressure, 14, 27, 33, 55, 57, 67, 69,
72, 84, 97, 98, 99, 105, 107, 108, 113,
114, 120, 126, 128, 129, 130, 131, 134,
147
pulse wave velocity (PVW), 14, 15, 42, 43,
44, 45, 46, 47, 49, 50, 54, 55, 56, 57, 59,
60, 61, 63, 65, 66, 67, 69, 71, 72, 77, 80,
82, 84, 85, 92, 94, 99, 119, 120, 121,
124, 126, 127, 128, 129, 130, 131, 132,
133, 134, 138, 139, 141, 142, 143, 144,
145, 146, 148, 149, 150
P-value, 142
pyrophosphate, 80, 90
Q
QRS complex, 46, 140
quadriceps, 146
quality of life, 37
quantification, 16, 31, 59
quantified, 79
quartile, 56, 82
R
radius, 4, 15
Raikou V. D., 135
RAS, 60, 61, 64, 65
rate-pressure product, 137, 138, 144, 145,
148, 150
reactions, 59, 60
reactive oxygen, 58, 59
receptor, 64, 65, 73, 78, 83, 92
receptors, 122
recovery, 122, 140
reduced lung function, 57
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165
regional arterial stiffness, 14, 42, 45, 50, 51,
120
regression, 10, 18, 44, 84, 85, 97, 101, 102,
106, 107, 108, 110, 111, 120, 125, 126,
127, 128, 138, 141, 142, 143, 146, 148,
149, 150
regression analysis, 10, 18, 84, 102, 106,
107, 108, 120, 125, 126, 127, 128, 138,
142, 143, 146, 148, 149, 150
regression line, 101, 111, 141
relevance, 21, 23
reliability, 35
renal failure, 123
renal osteodystrophy, 95
renal replacement therapy, 119, 121, 127,
128, 129, 131, 132
renin, 49, 60, 73
repair, 66, 70
repetitions, 139
reserves, 35, 38
resistance, 1, 3, 5, 8, 9, 11, 12, 13, 23, 27,
28, 29, 124, 137, 138, 139, 143, 144,
145, 146, 147, 150, 151, 152, 153
respiration, 140
response, 8, 11, 21, 22, 25, 27, 30, 32, 58,
69, 73, 109, 138, 143, 146, 152
retinopathy, 98, 99, 100, 101, 102, 103, 105,
109, 117
rheumatoid arthritis, 80, 89
risk, 22, 23, 24, 33, 41, 43, 47, 48, 50, 53,
54, 55, 56, 57, 58, 60, 64, 66, 69, 71, 72,
81, 82, 84, 85, 87, 92, 94, 95, 98, 99,
109, 110, 116, 138, 153
risk factors, 22, 41, 43, 47, 48, 53, 54, 55,
57, 58, 84, 85, 94, 99, 109, 153
S
safety, 86
saturation, 61
scleroderma, 4, 26
sclerosis, 85
sclerostin, 75, 76, 78, 79, 81, 85, 86, 87, 88,
89, 90, 91, 95, 96
senescence, 72
sensitivity, 15, 23, 124, 137, 138, 144, 145,
146, 148, 149, 150, 153
sensor, 124
serine, 14
serotonin, 14
serum, 59, 70, 77, 79, 80, 81, 82, 84, 85, 88,
89, 90, 91, 92, 93, 95, 116, 120, 123,
124, 129, 130, 131
serum albumin, 129
serum bicarbonate, 120, 123, 124, 129, 130,
131
sex, 41, 43, 55, 56, 60, 79, 125, 126, 127,
128, 150
sickle cell, 31
side effects, 86
signaling pathway, 75, 78, 83, 135
signalling, 89
signals, 83, 135
signs, 102, 122, 139
skeletal muscle, 153
skin, 60, 61, 62, 65, 78
smoking, 41, 43, 49, 53, 54, 55, 56, 57, 62,
69, 85, 125, 126, 127, 128
smooth muscle, 5, 13, 20, 25, 30, 32, 58, 59,
76, 78, 80, 90, 95
smooth muscle cells, 13, 20, 25, 76, 78, 90,
95
sodium, 122, 123, 126, 128, 129, 131
software, 46, 125, 141
solution, 122
Spain, 1
species, 8, 13, 58, 59
specifications, 124
spectroscopy, 133
speculation, 85
sphygmomanometer, 101, 124
spinal cord, 153
spine, 81
spontaneous abortion, 116
sputum, 60
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Index
166
standard deviation, 9, 125
state, 9, 25, 65, 110, 120, 123, 131, 132
statin, 72, 122
statistics, 102
stenosis, 38, 82
stimulation, 59, 61
storage, 4, 5
strength training, 153
stress, 13, 25, 59, 60, 65, 70, 152
stress test, 152
stress testing, 152
stretching, 139, 140
stroke, 5, 11, 27, 57, 68, 99, 110
stroke volume, 5, 11, 110
structural changes, 12, 20
structure, 32, 43, 54, 60
subgroups, 46
subtraction, 102
Sun, 32
supplementation, 153, 155
surfactant, 38
survival, 22, 26, 83, 91, 94, 95, 129, 133
survival rate, 129
susceptibility, 70
Sweden, 114
sympathetic nervous system, 54, 58, 61
symptoms, 2, 22, 139
syndrome, 59, 60, 72, 116, 117, 122
synergistic effect, 85
synthesis, 14, 65, 78
systemic inflammation, 54, 58, 59, 60, 62,
63, 64, 65, 66, 69, 70
systemic sclerosis, 22, 23, 24, 33, 50
systolic blood pressure, 56, 84, 125, 131,
137, 138, 144, 145, 146, 149
systolic pressure, 57, 65
T
T cell, 61, 83
target, 14, 41, 42, 43, 44, 59, 73, 99, 111,
113
target organs, 59
Task Force, 27
technical assistance, 112
technician, 112
techniques, 24, 29
telomere, 62, 72
telomere shortening, 72
testing, 11, 15, 21, 22, 33, 35, 38, 139
TGF, 14, 78, 83
therapeutic approaches, 33
therapeutic targets, 89
therapy, 21, 25, 42, 49, 50, 54, 70, 72, 73,
95, 96, 122, 129
thrombosis, 37, 57
tibia, 77
time periods, 46
tissue, 14, 27, 59, 60, 73, 80, 121
TNF, 58, 83
TNF-α, 58, 83
tobacco, 71
tobacco smoking, 71
tonometry, 50, 141
training, 138, 143, 151, 152
training programs, 152
transducer, 44, 124
transformation, 6
transforming growth factor, 78
transmission, 13, 14, 20
transplant, 36, 37, 80, 82, 85, 95, 103
transplant recipients, 36, 37, 80, 82, 85
transplantation, 37, 51, 79, 84, 90, 93, 103,
122
treatment, 27, 28, 29, 43, 44, 50, 63, 64, 68,
72, 84, 85, 86, 96, 98, 103, 110, 115,
117, 122, 123, 124, 132
trial, 63, 80, 86, 117, 133
triglycerides, 142
tumor, 58, 83, 116
tumor necrosis factor, 58, 83
turnover, 75, 76, 77, 83, 85, 86
type 1 diabetes, 55, 67, 84, 93, 97, 99, 104,
114, 116, 117
type 2 diabetes, 51, 82, 91, 117
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