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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5713_Библиотеки_им_академика_М_И_Перельмана
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Metals in Medicine, Volume 1
such as liposomes, micelles, peptides, synthetic polymers, or dendrimers are
used to engineer the DDS.
58,59
cellular targets in reaction to both internal and exterior stimuli including
thermal, photo, ultrasound, magnetic, and electrical stimuli, alteration in pH
60
In cancer therapy,
increase the drug delivery and accumulation in the cancer tissue, leading to
improved tumor cell management.
61
this area.
-
rial, has received considerable interest. It has been used in many areas,
material catalysis, material sensing, material bioimaging, material energy
storage, material medication delivery, and more. Relative to conventional
covalent bonds, and others, pharmaceuticals may be chemically conjugated
-
s
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195
use the changes in the pH.
62
63
64
pH-responsive
vectors are characteristically constructed employing the polymers that
be biocompatible.
bioactivity, and good mechanical properties.
62
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Metals in Medicine, Volume 1
isotherm model.
63
65,66
67
adsorption take place in liquid phases, MOFs magnetic properties should
68,69
70
-
2
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197
cm
3
1
72
As a
cationic MOFs. Even though cationic MOFs possess inherent characteristics
73,74
ligands, imposing a partial positive pore environment that is countered by
residual counterions residing in the empty space. Despite this, cationic MOFs
anion-exchangers, and cationic MOFs are 1D or 2D coordination polymers
(CPs) that date back to the early 2000s.
72
materials, solution-phase molecular assemblies, and small molecules, using
MOFs as an alternate approach has inherent advantages in the simplicity
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Metals in Medicine, Volume 1
groups on the ligand.
72,73
apply a similar idea to MOF-based anion receptors since doing so involves
72
polymer poly(N
75
In
comparatively mild-operating environments, thermal-responsive MOFs are
thermal-responsive MOFs are designed according to electronic dispersion
-
-
76,77
Unusual thermomechanical characteristics, such as “colossal” positive
-
75
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199
75,76
s
novelty resides in possessing a high exterior area and their capability to
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Metals in Medicine, Volume 1
pressure is termed as gate opening pressure.
78,79
-
78
When O
2
-
MOFs. Supercritical N
2
, O
2
, CH
4
, and CO
2
high-pressure excess-adsorption
2
> O
2
>
CH
4
> CO
2
-
78
s
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201
light. Photoresponsive MOFs absorb the incident energy and get converted
-
photoresponsive elements involved intrinsically or they have photothera-
peutic agents involved nonintrinsically. Intrinsic ones are again divided into
MOF is NH
2
small molecules.
80
and unloading a hydrogenation catalyst called tetramethyl ethylenediamine
81
s
82
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Metals in Medicine, Volume 1
such a coating procedure, MOFs may be used in extensive sectors including
using conventional desiccating agents or adsorbents are even less competi-
83,84
85
s
86
With iron, aluminum,
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203
theranostics, molecular imaging, and drug administration may be expanded
2
87–89
s
90
2+
,
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