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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5950_Библиотеки_им_академика_М_И_Перельмана
.pdf
184
Metals in Medicine, Volume 2
-
-
28
TABLE 6.2 Drug Release Kinetic Models.
Kinetic model Equation Rate constant Reference
Zero-Order
0t
M M kt
∞
−=
K
0
(Gouda et al., 2017)
First-Order
1
1
t
M
kt
M
∞
= −
K
1
: First-order
Higuchi
0.5
t
H
K
M
t
M
∞
=
K
H
: Higuchi (Gouda et al., 2017)
Bhaskar
0.65
1
t
B
K
M
t
M
∞
= −
K
B
: Bhaskar
0.65
1
t
B
K
M
t
M
∞
= −
K
HC
Korsmeyer-Peppas
n
t
kp
K
M
t
M
∞
=
K
KP
: Korsmeyer-Peppas (Gouda et al., 2017)
M
t
Gnanasekar et al.
31
(ChR) nanostructures, ChR@Ag NPs-rGO-based, and ChR@Au NPs-rGO
https://t.me/med1917
Silver/Gold Nanoparticle for Photothermal Therapy of Cancer
185
(Ag
and Au
-
posite under various physiological conditions are enhanced by the presence
-
31
Hembram
et al.
32
50
activity values
Ag NPs.
32
Balamurugan and Govindasamy
33
using Pandanus canaranus
-
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Metals in Medicine, Volume 2
Artemia salina nauplii
50
membranes, and damage to the nuclei. In summary, P. canaranus is a good
candidate to be used as a nano-based anticancer medicine to counteract the
33
Using Ulva lactuca (UL) extract,
34
-
UL-Au and UL-Ag nanoparticles exhibited very good biocompatibility in
34
35
Commiphora wightii (CW)-based Au NPs and their anticancer activity on
NPs had a strong anticancer activity against MCF-7 breast cancer cell lines.
35
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6.6 Ag AND Au NPs FOR OPTICAL IMAGING SYSTEMS
technique, and it is connected to these plasmonic characteristics (SERS).
delivery, etc.
36
-
provides imaging properties.
37
In recent years, imaging techniques in biotechnology, medicine, and
-
steps, makes less noise, and can be tested directly. Additionally, it permits
38,39
40
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Metals in Medicine, Volume 2
41,42
-
since there is no probe involved.
43
With ultrasonic signals dispersing much
less than light, photoacoustic imaging is a technique that combines ultra-
biological imaging systems.
44
resonance, Kim et al.
45
developed plasmonic Au NPs as contrast agents
including optical coherence tomography to detect early-stage cancers. In
-
(hamster control pouch) model containing early-stage squamous carcinoma
45
al.
46
2
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46
In 2019, Hada et al.
47
-
level and bioimaging using Raman microscopy.
47
In order to observe the
alpha) in ER-positive MCF-7 cells, Kapara et al.
48
developed a basic and
3D SERS cell mapping, indicates that ER-Au NPs enter MCF-7 cell lines
48
Chu et al.
49
used
that it had a biocompatible natural content.
49
42
and iron oxide (Fe
2
O
3
plasmonic-magnetic hybrid nanoparticles ((doxorubicin (Dox), Au NPs,
and Fe
2
O
3
nanocluster). It has been demonstrated that photoacoustic and
techniques.
42
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Metals in Medicine, Volume 2
6.7 POLYMER/Ag NPs AND Au NPs FOR CANCER TREATMENT
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an average 10 million human deaths in 2020. In addition, the World Health
methods such as hormone therapy, smart drug therapy, photothermal therapy,
traditional therapy options by simultaneously diagnosing and treating cancer
cells using a smart nanostructure-based drug delivery approach.
50
Au NPs
study, Daei et al.
51
Au NPs nanoparticles on human bladder tumor 5637 cell lines and investigated
-
Experimental
51
52
evaluated cisplatin
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increase in urea and creatinine, an enormous decrease in erythrocyte and
Bax and caspase-3 mRNA expressions, and obvious structural changes. It
53
used a nanocomposite
molecularly imprinted polymer (MIP) via a glassy carbon electrode (GCE).
Although IMQ is an anticancer drug, it damages the skin at high concentra-
FIGURE 6.2 Cancer treatment.
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Metals in Medicine, Volume 2
compound.
53
6.8 APPLICATION OF NANOPARTICLES IN PHOTOTHERMAL
THERAPY
methods such as chemotherapy and surgery in cancer treatment. Among
nanomaterials have been and are still being investigated as agents to improve
54
FIGURE 6.3
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cancer have been studied. He et al.
55
(gold-polyvinylpyrrolidone@(Iron) Lavoisier Institute Materials-100) nano-
-
are potential materials in cancer treatments.
55
Au nanostructures can also be
56
Ziziphus ziziphus plant.
As the concentration
increased, so did the temperature.
56
57
-
examined against E. Coli and S. aureus
S. aureusthe thermal temperature increased
to 50°C
improved collagen deposition and angiogenesis, increased tissue repair, and
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