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CARDIOLOGY RESEARCH AND CLINICAL DEVELOPMENTS
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PERSPECTIVES IN
AORTIC VALVE DISEASE
CLINICAL AND MORPHOLOGICAL
CHARACTERISTICS, DIAGNOSIS
AND TREATMENTS
No part of this digital document may be reproduced, stored in a retrieval system or transmitted in any form or
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expressed or implied warranty of any kind and assumes no responsibility for any errors or omissions. No
liability is assumed for incidental or consequential damages in connection with or arising out of information
contained herein. This digital document is sold with the clear understanding that the publisher is not engaged in
rendering legal, medical or any other professional services.
CARDIOLOGY RESEARCH AND
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CLINICAL DEVELOPMENTS
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PERSPECTIVES IN
AORTIC VALVE DISEASE
CLINICAL AND MORPHOLOGICAL
CHARACTERISTICS, DIAGNOSIS
AND TREATMENTS
GIOVANNI CONCISTRÈ
EDITOR
Copyright © 2020 by Nova Science Publishers, Inc.
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The Publisher has taken reasonable care in the preparation of this book, but makes no expressed or implied warranty of any
kind and assumes no responsibility for any errors or omissions. No liability is assumed for incidental or consequential
damages in connection with or arising out of information contained in this book. The Publisher shall not be liable for any
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Independent verification should be sought for any data, advice or recommendations contained in this book. In addition, no
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This publication is designed to provide accurate and authoritative information with regard to the subject matter covered
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Additional color graphics may be available in the e-book version of this book.
Library of Congress Cataloging-in-Publication Data
Names: Concistrè, Giovanni, editor.
Title: Perspectives in aortic valve disease : clinical and morphological
characteristics, diagnosis and treatments / Giovanni Concistrè,
Ospedale del Cuore "G. Pasquinucci", Massa, Italy, editor.
Description: New York : Nova Science Publishers, [2021] | Series:
Cardiology research and clinical developments | Includes bibliographical
references and index. |
Identifiers: LCCN 2020046281 (print) | LCCN 2020046282 (ebook) | ISBN
9781536187694 (hardcover) | ISBN 9781536188486 (adobe pdf)
Subjects: LCSH: Heart valves--Diseases--Treatment. | Aortic
valve--Diseases. | Cardiology.
Classification: LCC RC685.V2 P47 2021 (print) | LCC RC685.V2 (ebook) |
DDC 616.1/2506--dc23
LC record available at https://lccn.loc.gov/2020046281
LC ebook record available at https://lccn.loc.gov/2020046282
Published by Nova Science Publishers, Inc. † New York
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CONTENTS
Foreword ix
Tirone David
Preface xi
Chapter 1 Surgical Anatomy and Pathology of Aortic Valve:
Morphogenesis, Normal and Pathological Anatomy 1
Giacomo Bianchi
Chapter 2 Epidemiology and Clinical Approach to Aortic Valve Disease 17
Claudio Passino, Valentina Galfo, Simone Gasparini,
Filippo Quattrone, Octavian Vatavu and Alberto Aimo
Chapter 3 Non-Invasive Imaging of Aortic Valve – Ultrasounds:
Trans-Thoracic, Trans-Esophageal and Stress Echocardiography 37
Alberto Giannoni, Chiara Borrelli, Giulia Elena Mandoli
and Francesco Gentile
Chapter 4 Advanced Imaging and Functional Tools for Aortic Valve
Assessment: Cardiovascular Magnetic Resonance and
Cardiac Computed Tomography Angiography 55
Andrea Barison and Alberto Clemente
Chapter 5 Degenerative Aortic Valve Disease 83
Michele Emdin, Lucio Teresi, Samuele Cannas, Alberto Aimo
and Claudio Passino
Chapter 6 Aortic Valve Endocarditis: Epidemiology, Treatment and Outcomes 97
Michele Danilo Pierri, Mariano Cefarelli, Paolo Berretta,
Jacopo Alfonsi, Luca Montecchiani and Marco Di Eusanio
Chapter 7 Neoplastic Disorders Involving the Aortic Valve 125
Angela Pucci, Alessandra Burini, Enrica Manzato
and Cristina Zucchinetti
Chapter 8 Aortic Root Involvement in Congenital Heart Defects:
Special Surgical Topics 145
Vitali Pak, Elisa Barberi and Duccio Federici
Contents
viii
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Chapter 9 Adult Bicuspid Aortic Valve 179
Alessandro Della Corte and Federica Lo Presti
Chapter 10 Management of Aortic Valve Disease in LVADs 203
A. Montalto, C. Amarelli, K. Hopkins, V. Piazza and F. Musumeci
Chapter 11 Multidisciplinary Approach to the Treatment of
Aortic Valve Disease: The Role of the Heart Team 217
Giovanni Concistrè
Chapter 12 Pharmacological Treatment of Aortic Valve Disease 229
Giovanni Concistrè
Chapter 13 Surgical Treatment of Aortic Valve Disease:
Indications, Risk Stratification and Outcomes 253
Rafik Margaryan
Chapter 14 Surgical Approach:
Conventional and Minimally Invasive Treatments 273
Giovanni Concistrè and Marco Solinas
Chapter 15 Totally Endoscopic Aortic Valve Replacement (EAVR) 287
Tommaso Hinna Danesi
Chapter 16 REDO Surgery for Aortic Valve:
Demographics and Operative Options 297
Antonio Miceli and Mattia Glauber
Chapter 17 Aortic Prosthesis: Mechanical and Sutured Biological Valves 305
Giuseppe Santarpino, Giuseppe Filiberto Serraino
and Pasquale Mastroroberto
Chapter 18 New Generation of Aortic Bioprosthesis:
Sutureless and Rapid Deployment Valves 315
Giovanni Concistrè, Francesca Chiaramonti and Marco Solinas
Chapter 19 Aortic Valve Repair 337
Stefano Mastrobuoni, Laurent De Kerchove and Gebrine El Khoury
Chapter 20 Aortic Valve Sparing: Remodeling and Reimplantation 363
Ruggero De Paulis, Raffaele Scaffa and Ilaria Chirichilli
Chapter 21 Transcatheter Therapy: Devices and Techniques 389
Francesco Maisano and Giulio Russo
About the Editor 409
Index 411
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