Добавил:
Sekretar
kiopkiopkiop18@yandex.ru
t.me/Prokururor I Вовсе не секретарь, но почту проверяю
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз:
Предмет:
Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3795_Библиотеки_им_академика_М_И_Перельмана
.pdf
Aortic Valve Endocarditis
117
Complimentary Contributor Copy
https://t.me/med1917
[44] Evangelista, A., and M. T. González-Alujas. 2004. “Echocardiography in Infective
Endocarditis.” In Heart, 90:614–17. https://doi.org/10.1136/hrt.2003.029868.
[45] Sordelli, Chiara, Nunzia Fele, Rosa Mocerino, Sara Weisz, Luigi Ascione, Pio Caso,
Antonio Carrozza, Carlo Tascini, Stefano De Vivo, and Sergio Severino. 2019.
“Infective Endocarditis: Echocardiographic Imaging and New Imaging Modalities.”
Journal of Cardiovascular Echography. Wolters Kluwer Medknow Publications.
https://doi.org/10.4103/jcecho.jcecho_53_19.
[46] Fagman, Erika, Sossio Perrotta, Odd Bech-Hanssen, Agneta Flinck, Carl Lamm, Lars
Olaison, and Gunnar Svensson. 2012. “ECG-Gated Computed Tomography: A New
Role for Patients with Suspected Aortic Prosthetic Valve Endocarditis.” European
Radiology 22 (11): 2407–14. https://doi.org/10.1007/s00330-012-2491-5.
[47] Habets, Jesse, Wilco Tanis, Lex A van Herwerden, Renee B A van den Brink, Willem
P Th M Mali, Bas A J M de Mol, Steven A J Chamuleau, and Ricardo P J Budde.
2014. “Cardiac Computed Tomography Angiography Results in Diagnostic and
Therapeutic Change in Prosthetic Heart Valve Endocarditis.” The International
Journal of Cardiovascular Imaging 30 (2): 377–87. https://doi.org/10.1007/s10554-
013-0335-2.
[48] Pizzi, Mariá N., Albert Roque, Nuria Fernández-Hidalgo, Hug Cuéllar-Calabria,
Ignacio Ferreira-González, Mariá T. Gonzàlez-Alujas, Gerard Oristrell, et al. 2015.
“Improving the Diagnosis of Infective Endocarditis in Prosthetic Valves and
Intracardiac Devices with 18F-Fluordeoxyglucose Positron Emission
Tomography/Computed Tomography Angiography: Initial Results at an Infective
Endocarditis Referral Center.” Circulation 132 (12): 1113–26. https://doi.org/
10.1161/CIRCULATIONAHA.115.015316.
[49] Erba, Paola A, Umberto Conti, Elena Lazzeri, Martina Sollini, Roberta Doria,
Salvatore M De Tommasi, Francesco Bandera, et al. 2012. “Added Value of 99mTcHMPAO-Labeled Leukocyte SPECT/CT in the Characterization and Management of
Patients with Infectious Endocarditis.” Journal of Nuclear Medicine : Official
Publication, Society of Nuclear Medicine 53 (8): 1235–43. https://doi.org/
10.2967/jnumed.111.099424.
[50] Bartoletti, Michele, Fabio Tumietto, Giovanni Fasulo, Maddalena Giannella,
Francesco Cristini, Rachele Bonfiglioli, Luigi Raumer, et al. 2014. “Combined
Computed Tomography and Fluorodeoxyglucose Positron Emission Tomography in
the Diagnosis of Prosthetic Valve Endocarditis: A Case Series.” BMC Research Notes
7 (1). https://doi.org/10.1186/1756-0500-7-32.
[51] Ricciardi, Alessandra, Pasquale Sordillo, Laura Ceccarelli, Gaetano Maffongelli,
Giorgio Calisti, Barbara Di Pietro, Cristiana Ragano Caracciolo, et al. 2014. “18Fluoro-2-Deoxyglucose Positron Emission Tomography-Computed Tomography: An
Additional Tool in the Diagnosis of Prosthetic Valve Endocarditis.” International
Journal of Infectious Diseases 28 (November): 219–24. https://doi.org/
10.1016/j.ijid.2014.04.028.
[52] Li, J. S., D. J. Sexton, N. Mick, R. Nettles, V. G. Fowler, T. Ryan, T. Bashore, and G.
R. Corey. 2000. “Proposed Modifications to the Duke Criteria for the Diagnosis of
Infective Endocarditis.” Clinical Infectious Diseases 30 (4): 633–38. https://doi.org/
10.1086/313753.
Michele Danilo Pierri, Mariano Cefarelli, Paolo Berretta et al.
118
Complimentary Contributor Copy
https://t.me/med1917
[53] Shrestha, Nabin, Sampurna Shakya, Syed Hussain, Gosta Pettersson, Brian Griffin,
and Steven Gordon. 2017. “Sensitivity and Specificity of Duke Criteria for Diagnosis
of Definite Infective Endocarditis: A Cohort Study.” Open Forum Infectious Diseases
4 (suppl_1): S550–51. https://doi.org/10.1093/ofid/ofx163.1431.
[54] Baddour, Larry M., Walter R. Wilson, Arnold S. Bayer, Vance G. Fowler, Imad M.
Tleyjeh, Michael J. Rybak, Bruno Barsic, et al. 2015. “Infective Endocarditis in
Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A
Scientific Statement for Healthcare Professionals from the American Heart
Association.” Circulation. Lippincott Williams and Wilkins. https://doi.org/10.1161/
CIR.0000000000000296.
[55] Iversen, Kasper, Nikolaj Ihlemann, Sabine U. Gill, Trine Madsen, Hanne Elming,
Kaare T. Jensen, Niels E. Bruun, et al. 2019. “Partial Oral versus Intravenous
Antibiotic Treatment of Endocarditis.” New England Journal of Medicine 380 (5):
415–24. https://doi.org/10.1056/NEJMoa1808312.
[56] Tobudic, Selma, Christina Forstner, Heinz Burgmann, Heimo Lagler, Michael
Ramharter, Christoph Steininger, Matthias G Vossen, Stefan Winkler, and Florian
Thalhammer. 2018. “Dalbavancin as Primary and Sequential Treatment for GramPositive Infective Endocarditis: 2-Year Experience at the General Hospital of Vienna.”
Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society
of America 67 (5): 795–98. https://doi.org/10.1093/cid/ciy279.
[57] Chu, Vivian H., Lawrence P. Park, Eugene Athan, Francois Delahaye, Tomas
Freiberger, Cristiane Lamas, Jose M. Miro, et al. 2015. “Association between Surgical
Indications, Operative Risk, and Clinical Outcome in Infective Endocarditis a
Prospective Study from the International Collaboration on Endocarditis.” Circulation
131 (2): 131–40. https://doi.org/10.1161/CIRCULATIONAHA.114.012461.
[58] Iung, Bernard, Thanh Doco-Lecompte, Sidney Chocron, Christophe Strady, François
Delahaye, Vincent Le Moing, Claire Poyart, et al. 2016. “Cardiac Surgery during the
Acute Phase of Infective Endocarditis: Discrepancies between European Society of
Cardiology Guidelines and Practices.” European Heart Journal 37 (10): 840–48.
https://doi.org/10.1093/eurheartj/ehv650.
[59] Vilacosta, Isidre, Catherine Graupner, JoséAlberto SanRomán, Cristina Sarriá, Ricardo
Ronderos, Cristina Fernández, Leonardo Mancini, Olga Sanz, Juan Victor Sanmartín,
and Walter Stoermann. 2002. “Risk of Embolization after Institution of Antibiotic
Therapy for Infective Endocarditis.” Journal of the American College of Cardiology
39 (9): 1489–95. https://doi.org/10.1016/S0735-1097(02)01790-4.
[60] Steckelberg, J M, J G Murphy, D Ballard, K Bailey, A J Tajik, C P Taliercio, E R
Giuliani, and W R Wilson. 1991. “Emboli in Infective Endocarditis: The Prognostic
Value of Echocardiography.” Annals of Internal Medicine 114 (8): 635–40.
https://doi.org/10.7326/0003-4819-114-8-635.
[61] Kang, Duk Hyun, Yong Jin Kim, Sung Han Kim, Byung Joo Sun, Dae Hee Kim, Sung
Cheol Yun, Jong Min Song, et al. 2012. “Early Surgery versus Conventional
Treatment for Infective Endocarditis.” New England Journal of Medicine 366 (26):
2466–73. https://doi.org/10.1056/NEJMoa1112843.
Aortic Valve Endocarditis
119
Complimentary Contributor Copy
https://t.me/med1917
[62] Revilla, Ana, Javier López, Isidre Vilacosta, Eduardo Villacorta, María J Rollán, José
R Echevarría, Yolanda Carrascal, et al. 2007. “Clinical and Prognostic Profile of
Patients with Infective Endocarditis Who Need Urgent Surgery.” European Heart
Journal 28 (1): 65–71. https://doi.org/10.1093/eurheartj/ehl315.
[63] Tleyjeh, I M, J M Steckelberg, G Georgescu, H M K Ghomrawi, T L Hoskin, F B
Enders, F Mookadam, W C Huskins, W R Wilson, and L M Baddour. 2008. “The
Association between the Timing of Valve Surgery and 6-Month Mortality in LeftSided Infective Endocarditis.” Heart (British Cardiac Society) 94 (7): 892–96.
https://doi.org/10.1136/hrt.2007.118968.
[64] Lalani, Tahaniyat, Christopher H Cabell, Daniel K Benjamin, Ovidiu Lasca, Christoph
Naber, Vance G Fowler, G Ralph Corey, et al. 2010. “Analysis of the Impact of Early
Surgery on In-Hospital Mortality of Native Valve Endocarditis: Use of Propensity
Score and Instrumental Variable Methods to Adjust for Treatment-Selection Bias.”
Circulation 121 (8): 1005–13. https://doi.org/10.1161/CIRCULATIONAHA.109.
864488.
[65] Thuny, Franck, Sylvain Beurtheret, Julien Mancini, Vlad Gariboldi, Jean-Paul Casalta,
Alberto Riberi, Roch Giorgi, et al. 2011. “The Timing of Surgery Influences Mortality
and Morbidity in Adults with Severe Complicated Infective Endocarditis: A Propensity
Analysis.” European Heart Journal 32 (16): 2027–33. https://doi.org/10.1093/
eurheartj/ehp089.
[66] Liang, Fuxiang, Bing Song, Ruisheng Liu, Liu Yang, Hanbo Tang, and Yuanming Li.
2016. “Optimal Timing for Early Surgery in Infective Endocarditis: A Meta-Analysis.”
Interactive Cardiovascular and Thoracic Surgery 22 (3): 336–45. https://doi.org/
10.1093/icvts/ivv368.
[67] Yoshioka, Daisuke, Taichi Sakaguchi, Takashi Yamauchi, Shuhei Okazaki, Shigeru
Miyagawa, Hiroyuki Nishi, Yasushi Yoshikawa, Satsuki Fukushima, Shunsuke Saito,
and Yoshiki Sawa. 2012. “Impact of Early Surgical Treatment on Postoperative
Neurologic Outcome for Active Infective Endocarditis Complicated by Cerebral
Infarction.” The Annals of Thoracic Surgery 94 (2): 489–95; discussion 496.
https://doi.org/10.1016/j.athoracsur.2012.04.027.
[68] Tam, Derrick Y., Bobby Yanagawa, Subodh Verma, Marc Ruel, Stephen E. Fremes,
Amine Mazine, Seana Adams, and Jan O. Friedrich. 2018. “Early vs Late Surgery for
Patients With Endocarditis and Neurological Injury: A Systematic Review and MetaAnalysis.” Canadian Journal of Cardiology. Elsevier Inc. https://doi.org/10.1016/
j.cjca.2018.05.010.
[69] García-Cabrera, Emilio, Nuria Fernández-Hidalgo, Benito Almirante, Radka Ivanova-
Georgieva, Mariam Noureddine, Antonio Plata, Jose M Lomas, et al. 2013.
“Neurological Complications of Infective Endocarditis: Risk Factors, Outcome, and
Impact of Cardiac Surgery: A Multicenter Observational Study.” Circulation 127 (23):
2272–84. https://doi.org/10.1161/CIRCULATIONAHA.112.000813.
[70] Piper, C., M. Wiemer, H. D. Schulte, and D. Horstkotte. 2001. “Stroke Is Not a
Contraindication for Urgent Valve Replacement in Acute Infective Endocarditis.”
Journal of Heart Valve Disease 10 (6): 703–11.
[71] Ruttmann, Elfriede, Johann Willeit, Hanno Ulmer, Orest Chevtchik, Daniel Höfer,
Werner Poewe, Günther Laufer, and Ludwig C Müller. 2006. “Neurological Outcome
Michele Danilo Pierri, Mariano Cefarelli, Paolo Berretta et al.
120
Complimentary Contributor Copy
https://t.me/med1917
of Septic Cardioembolic Stroke after Infective Endocarditis.” Stroke 37 (8): 2094–99.
https://doi.org/10.1161/01.STR.0000229894.28591.3f.
[72] Barsic, Bruno, Stuart Dickerman, Vladimir Krajinovic, Paul Pappas, Javier Altclas,
Giampiero Carosi, José H Casabé, et al. 2013. “Influence of the Timing of Cardiac
Surgery on the Outcome of Patients with Infective Endocarditis and Stroke.” Clinical
Infectious Diseases : An Official Publication of the Infectious Diseases Society of
America 56 (2): 209–17. https://doi.org/10.1093/cid/cis878.
[73] Sabik, Joseph F., Bruce W. Lytle, Eugene H. Blackstone, Antonino G.M. Marullo,
Gosta B. Pettersson, and Delos M. Cosgrove. 2002. “Aortic Root Replacement with
Cryopreserved Allograft for Prosthetic Valve Endocarditis.” Annals of Thoracic
Surgery 74 (3): 650–59. https://doi.org/10.1016/S0003-4975(02)03779-7.
[74] Savage, Edward B, Paramita Saha-Chaudhuri, Craig R Asher, J Matthew Brennan, and
James S Gammie. 2014. “Outcomes and Prosthesis Choice for Active Aortic Valve
Infective Endocarditis: Analysis of the Society of Thoracic Surgeons Adult Cardiac
Surgery Database.” The Annals of Thoracic Surgery 98 (3): 806–14. https://doi.org/
10.1016/j.athoracsur.2014.05.010.
[75] Schneider, Adriaan W, Mark G Hazekamp, Michel I M Versteegh, Eline F
Bruggemans, Eduard R Holman, Robert J M Klautz, and Jerry Braun. 2016. “Stentless
Bioprostheses: A Versatile and Durable Solution in Extensive Aortic Valve
Endocarditis.” European Journal of Cardio-Thoracic Surgery : Official Journal of the
European Association for Cardio-Thoracic Surgery 49 (6): 1699–1704. https://doi.org/
10.1093/ejcts/ezv463.
[76] Perrotta, Sossio, and Salvatore Lentini. 2010. “In Patients with Severe Active Aortic
Valve Endocarditis, Is a Stentless Valve as Good as the Homograft?” Interactive
Cardiovascular and Thoracic Surgery 11 (3): 309–13. https://doi.org/
10.1510/icvts.2010.234831.
[77] Heinz, Anneliese, Julia Dumfarth, Elfriede Ruttmann-Ulmer, Michael Grimm, and
Ludwig C Müller. 2014. “Freestyle Root Replacement for Complex Destructive Aortic
Valve Endocarditis.” The Journal of Thoracic and Cardiovascular Surgery 147 (4):
1265–70. https://doi.org/10.1016/j.jtcvs.2013.05.014.
[78] Miceli, Antonio, Mariagrazia Croccia, Simone Simeoni, Egidio Varone, Michele
Murzi, Pier Andrea Farneti, Marco Solinas, and Mattia Glauber. 2013. “Root
Replacement with Stentless Freestyle Bioprostheses for Active Endocarditis: A Single
Centre Experience.” Interactive Cardiovascular and Thoracic Surgery 16 (1): 27–30.
https://doi.org/10.1093/icvts/ivs438.
[79] Perrotta, Sossio, and Salvatore Lentini. 2010. “In Patients with Severe Active Aortic
Valve Endocarditis, Is a Stentless Valve as Good as the Homograft?” Interactive
Cardiovascular and Thoracic Surgery 11 (3): 309–13. https://doi.org/10.1510/
icvts.2010.234831.
[80] Di Eusanio, Marco, Paolo Berretta, Jacopo Alfonsi, and Mariano Cefarelli. 2019.
“Aortic Root Endocarditis: A Biointegral Bioconduit Subannular Implantation.”
Annals of Cardiothoracic Surgery 8 (6): 713–14. https://doi.org/10.21037
/acs.2019.09.02.
[81] Leontyev, Sergey, Michael A. Borger, Paul Modi, Sven Lehmann, Jörg Seeburger,
Thorsten Doenst, and Friedrich W. Mohr. 2012. “Surgical Management of Aortic Root
Abscess: A 13-Year Experience in 172 Patients with 100% Follow-Up.” Journal of
Aortic Valve Endocarditis
121
Complimentary Contributor Copy
https://t.me/med1917
Thoracic and Cardiovascular Surgery 143 (2): 332–37. https://doi.org/10.1016/
j.jtcvs.2010.10.064.
[82] Elgalad, Abdelmotagaly, Amr Arafat, Tarek Elshazly, Mohamed Elkahwagy, Hossam
Fawzy, Ehab Wahby, Abdel-Hady Taha, et al. 2019. “Surgery for Active Infective
Endocarditis of the Aortic Valve With Infection Extending Beyond the Leaflets.”
Heart, Lung & Circulation 28 (7): 1112–20. https://doi.org/10.1016/j.hlc.2018.05.200.
[83] Knosalla, C, Y Weng, A C Yankah, H Siniawski, J Hofmeister, R Hammerschmidt, M
Loebe, and R Hetzer. 2000. “Surgical Treatment of Active Infective Aortic Valve
Endocarditis with Associated Periannular Abscess--11 Year Results.” European Heart
Journal 21 (6): 490–97. https://doi.org/10.1053/euhj.1999.1877.
[84] Mylonakis, Eleftherios, and Stephen B. Calderwood. 2001. “Infective Endocarditis in
Adults.” New England Journal of Medicine. https://doi.org/10.1056/NEJMra010082.
[85] Lalani, Tahaniyat, Vivian H Chu, Lawrence P Park, Enrico Cecchi, G Ralph Corey,
Emanuele Durante-Mangoni, Vance G Fowler, et al. 2013. “In-Hospital and 1-Year
Mortality in Patients Undergoing Early Surgery for Prosthetic Valve Endocarditis.”
JAMA Internal Medicine 173 (16): 1495–1504. https://doi.org/10.1001/
jamainternmed.2013.8203.
[86] Luciani, N., E. Mossuto, D. Ricci, M. Luciani, M. Russo, A. Salsano, A. Pozzoli, et al.
2017. “Prosthetic Valve Endocarditis: Predictors of Early Outcome of Surgical
Therapy. A Multicentric Study.” European Journal of Cardio-Thoracic Surgery 52 (4).
https://doi.org/10.1093/ejcts/ezx169.
[87] Lee, Jonathan H, Kimberly D Burner, Michael E Fealey, William D Edwards, Henry D
Tazelaar, Thomas A Orszulak, Alan J Wright, and Larry M Baddour. 2011. “Prosthetic
Valve Endocarditis: Clinicopathological Correlates in 122 Surgical Specimens from
116 Patients (1985-2004).” Cardiovascular Pathology : The Official Journal of the
Society for Cardiovascular Pathology 20 (1): 26–35. https://doi.org/10.1016/
j.carpath.2009.09.006.
[88] López, Javier, Ana Revilla, Isidre Vilacosta, Eduardo Villacorta, Carlos González-
Juanatey, Itziar Gómez, María Jesús Rollán, and José Alberto San Román. 2007.
“Definition, Clinical Profile, Microbiological Spectrum, and Prognostic Factors of
Early-Onset Prosthetic Valve Endocarditis.” European Heart Journal 28 (6): 760–65.
https://doi.org/10.1093/eurheartj/ehl486.
[89] Tan, Hwee-Leong, Louis Y A Chai, Tiong-Cheng Yeo, Boon-Lock Chia, Paul A
Tambyah, and Kian-Keong Poh. 2015. “Predictors of In-Hospital Adverse Events in
Patients with Prosthetic Valve Infective Endocarditis.” Heart, Lung & Circulation 24
(7): 705–9. https://doi.org/10.1016/j.hlc.2015.01.013.
[90] Brennan, J Matthew, Fred H Edwards, Yue Zhao, Sean O’Brien, Michael E Booth,
Rachel S Dokholyan, Pamela S Douglas, Eric D Peterson, and DEcIDE AVR
(Developing Evidence to Inform Decisions about Effectiveness–Aortic Valve
Replacement) Research Team. 2013. “Long-Term Safety and Effectiveness of
Mechanical versus Biologic Aortic Valve Prostheses in Older Patients: Results from
the Society of Thoracic Surgeons Adult Cardiac Surgery National Database.”
Circulation 127 (16): 1647–55. https://doi.org/10.1161/CIRCULATIONAHA.
113.002003.
Michele Danilo Pierri, Mariano Cefarelli, Paolo Berretta et al.
122
Complimentary Contributor Copy
https://t.me/med1917
[91] Østergaard, Lauge, Nana Valeur, Nikolaj Ihlemann, Morten Holdgaard Smerup,
Henning Bundgaard, Gunnar Gislason, Christian Torp-Pedersen, Niels Eske Bruun,
Lars Køber, and Emil Loldrup Fosbøl. 2018. “Incidence and Factors Associated with
Infective Endocarditis in Patients Undergoing Left-Sided Heart Valve Replacement.”
European Heart Journal 39 (28): 2668–75. https://doi.org/10.1093/eurheartj/ehy153.
[92] Tao, Ende, Li Wan, WenJun Wang, YunLong Luo, JinFu Zeng, and Xia Wu. 2017.
“The Prognosis of Infective Endocarditis Treated with Biological Valves versus
Mechanical Valves: A Meta-Analysis.” PloS One 12 (4): e0174519. https://doi.org/
10.1371/journal.pone.0174519.
[93] Anguera, Ignasi, Jose M. Miro, Jose Alberto San Roman, Aristides de Alarcon,
Manuel Anguita, Benito Almirante, Artur Evangelista, et al. 2006. “Periannular
Complications in Infective Endocarditis Involving Prosthetic Aortic Valves.”
American Journal of Cardiology 98 (9): 1261–68. https://doi.org/
10.1016/j.amjcard.2006.05.066.
[94] Wang, Andrew, Eugene Athan, Paul A. Pappas, Vance G. Fowler, Lars Olaison,
Carlos Paré, Benito Almirante, et al. 2007. “Contemporary Clinical Profile and
Outcome of Prosthetic Valve Endocarditis.” Journal of the American Medical
Association 297 (12): 1354–61. https://doi.org/10.1001/jama.297.12.1354.
[95] Morguet, A. J., G. S. Werner, S. Andreas, and H. Kreuzer. 1995. “Diagnostic Value of
Transesophageal Compared with Transthoracic Echocardiography in Suspected
Prosthetic Valve Endocarditis.” Herz 20 (6): 390–98.
[96] Musci, Michele, Michael Hübler, Aref Amiri, Julia Stein, Susanne Kosky, Rudolf
Meyer, Yuguo Weng, and Roland Hetzer. 2010. “Surgical Treatment for Active
Infective Prosthetic Valve Endocarditis: 22-Year Single-Centre Experience.” European
Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for
Cardio-Thoracic Surgery 38 (5): 528–38. https://doi.org/10.1016/j.ejcts.2010.03.019.
[97] Habib, Gilbert, C. Tribouilloy, F. Thuny, R. Giorgi, A. Brahim, M. Amazouz, J. P.
Remadi, et al. 2005. “Prosthetic Valve Endocarditis: Who Needs Surgery? A
Multicentre Study of 104 Cases.” Heart 91 (7): 954–59. https://doi.org/10.1136/
hrt.2004.046177.
[98] Eggebrecht, Holger, Sibylle Schelle, Miriam Puls, Björn Plicht, Ralph Stephan Von
Bardeleben, Christian Butter, Andreas E. May, et al. 2015. “Risk and Outcomes of
Complications during and after MitraClip Implantation: Experience in 828 Patients
from the German TRAnscatheter Mitral Valve Interventions (TRAMI) Registry.”
Catheterization and Cardiovascular Interventions 86 (4): 728–35. https://doi.org/
10.1002/ccd.25838.
[99] Chourdakis, Emmanouil, Ioanna Koniari, George Hahalis, Nicholas G. Kounis, and
Karl Eugen Hauptmann. 2018. “Endocarditis after Transcatheter Aortic Valve
Implantation: A Current Assessment.” Journal of Geriatric Cardiology. Science Press.
https://doi.org/10.11909/j.issn.1671-5411.2018.01.003.
[100] Carrasco-Chinchilla, Fernando, Gemma Sánchez-Espín, Josefa Ruiz-Morales, Isabel
Rodríguez-Bailón, Jose M Melero-Tejedor, Rada Ivanova-Georgieva, Victoria GarcíaLópez, Antonio Muñoz-García, Juan J Gómez-Doblas, and Eduardo de Teresa-Galván.
2014. “Influence of a Multidisciplinary Alert Strategy on Mortality Due to Left-Sided
Infective Endocarditis.” Revista Espanola de Cardiologia (English Ed.) 67 (5): 380–
86. https://doi.org/10.1016/j.rec.2013.09.010.
Aortic Valve Endocarditis
123
Complimentary Contributor Copy
https://t.me/med1917
[101] Chirillo, Fabio, Piergiorgio Scotton, Francesco Rocco, Roberto Rigoli, Elvio Polesel,
and Zoran Olivari. 2013. “Management of Patients with Infective Endocarditis by a
Multidisciplinary Team Approach: An Operative Protocol.” Journal of Cardiovascular
Medicine 14 (9): 659–68. https://doi.org/10.2459/JCM.0b013e32835ec585.
Complimentary Contributor Copy
https://t.me/med1917
In: Perspectives in Aortic Valve Disease ISBN: 978-1-53618-769-4
Complimentary Contributor Copy
https://t.me/med1917
Editor: Giovanni Concistrè © 2020 Nova Science Publishers, Inc.
Chapter 7
NEOPLASTIC DISORDERS INVOLVING
THE AORTIC VALVE
Angela Pucci
1,*
, Alessandra Burini
and Cristina Zucchinetti
1
Histopathology Department, University Hospital of Pisa
2
3
Sant’Anna School of Advanced Studies; Pisa, Italy
University of Pisa, Faculty of Medicine and Surgery, Pisa, Italy
ABSTRACT
Aortic valve tumors are rare and mainly represented by benign and small masses,
most commonly papillary fibroelastoma followed by myxoma. Malignant primary tumors
are exceptionally reported and are mainly represented by sarcomas. The aortic valve may
also present tumor-like lesions and pseudo-tumors, including thrombi, Lambl’s
excrescences and endocarditic vegetations. Although most aortic tumors are benign,
small and often asymptomatic lesions, they may have dramatic clinical consequences,
thus requiring surgical excision: embolic phenomena, outflow tract or coronary ostium
occlusion. They may be incidentally discovered by echocardiography – the main
diagnostic tool for cardiac masses. Computed tomography (CT) and cardiac magnetic
resonance (CMR) may give additional information on tumor size, shape, location and
characteristics, but definitive and differential diagnoses always require histology.
Keywords: cardiac tumors, magnetic resonance imaging, computed tomography
ABBREVIATIONS
CT computed tomography
EMA epithelial membrane antigen
FISH fluorescence in situ hybridisation
2,3
, Enrica Manzato
2,3
2,3
Corresponding Author’s Email: angelapucci@libero.it.
Angela Pucci, Alessandra Burini, Enrica Manzato et al.
126
Complimentary Contributor Copy
https://t.me/med1917
H&E hematoxylin/eosin
IE infectious endocarditis
IMT inflammatory myofibroblastic tumor
LE Lambl’s excrescences
CMR cardiac magnetic resonance
MRI magnetic resonance imaging
NBTE non-bacterial thrombotic endocarditis
PAS periodic acid-Schiff
PCR polymerase chain reaction
PFE papillary fibroelastoma
RT-PCR retro transcription-polymerase chain reaction
TEE transesophageal echocardiography
TTE transthoracic echocardiography
INTRODUCTION
Primary cardiac tumors are rare, with a prevalence at autopsy of 0.001-0.03% versus 1.5-
2.1% of secondary (metastatic) tumors. Valve tumors account for less than 10% of the heart
tumors [1–5]. Although most cardiac valve tumors are benign and of small dimensions, they
may have severe clinical sequelae and require surgical resection [1, 6, 7].
Cardiac valve tumors are more likely to occur in male (79% of cases) and adult patients,
the average age being 52 years (range, 2 to 88 years). Each of the four cardiac valves may be
involved with approximately equal frequency [4, 6, 7]. They are more commonly
asymptomatic, with overt symptoms in about 38% of patients, depending also upon a variable
risk of embolism, and including cardiac (angina, acute myocardial infarction, heart failure,
syncope and even sudden death) and neurological (transitory ischemic attack, stroke,
amaurosis) symptoms, but also mesenteric, renal, splenic or limb ischemia.
The most common aortic valve tumors are benign: papillary fibroelastoma (PFE),
followed by myxoma, fibroma and hemangioma. Malignant tumors are exceptionally reported
and almost exclusively represented by sarcomas and lymphomas, but both of them are more
frequently found in the right side of the heart [5]. Average tumor size is 1.15 cm (range: 0.3
to 7 cm). A few cases have also been reported of secondary involvement of the aortic valve
by tumors originating in different cardiac structures or other organs/tissues [1, 3, 5]. Although
most tumor masses are nowadays identified in vivo by imaging techniques – first
echocardiography for diagnosis, followed by computed tomography (CT) and cardiac
magnetic resonance (CMR) for better definition of tumor characteristics – the definitive
diagnosis of aortic valve tumors requires histology, which also represents the gold standard
for the differential diagnosis of cardiac tumors [5].
Соседние файлы в папке Библиотека им академика М.И. Перельмана