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Frailty syndrome clinic, diagnosis, treatment. Study aid

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care. At a Community Care and Long Term Care Need Level of 2 or higher, the patient's information should be forwarded to social services.
Comments: An individual case management plan, developed on the basis of a comprehensive geriatric assessment, aims to plan long-term care and care for a patient with frailty in close cooperation with medical and social services. The social status of the patient is partially assessed by all members of the geriatric team, but the most complete assessment is carried out by a social work specialist. When conducting a comprehensive geriatric assessment, they clarify data on the level of education, profession, family status of the patient, with whom the patient lives, to whom he turns for help if necessary, assess the safety of life, identify signs of neglect, self- neglect and abuse of an elderly person.
5.7. THE ROLE OF NURSING PERSONNEL
IN COMPREHENSIVE GERIATRIC ASSESSMENT
An important role in the management of patients in the geriatric department belongs to the nursing staff. Nursing staff are actively involved in performing a number of tests in a comprehensive geriatric assessment (Table 5).
Table 5
Components of a comprehensive geriatric assessment
and the participation of a nurse in its implementation
Domain
Domain
Components
Assessment tools
Comments
physical health
chronic diseases
Data of anamnesis and medical records
Assessed by the doctor
Drug therapy
STOPP/START criteria and other scales according to the guidelines Pharmacotherapy in elderly and senile patients
Assessed by the doctor
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Domain
Domain
Components
Assessment tools
Comments
Anthropometry
Measurement of height and weight
Carried out by a nurse
Orthostatic hypotension
Orthostatic test
Carried out by a nurse
Vision and hearing
Rosenbaum table Audiometry
Carried out by a nurse
Power status Body mass index
Nurse counts
Brief Nutritional Rating Scale
Completed by a nurse
Availability of required vaccinations
Medical records data
Can be assessed by a doctor or nurse
functional activity
Basic functional activity
Barthel index
Completed by a nurse
Instrumental functional activity
Lawton scale
Completed by a nurse
Mobility
Get Up and Walk Test Short Battery of Physical Functioning Tests
Carried out by a nurse
muscle strength
Carpal dynamometry
Carried out by a nurse
Psycho
-emotional
sphere
cognitive functions
Mini Clock Drawing Test COG Mini-Mental Status Scale or Montreal Cognitive Assessment Battery of Frontal Dysfunction Tests
Conducted by a doctor or nurse trained to perform these tests. The set of tests may vary depending on the specific situation.
Emotional condition
Geriatric Depression Scale Health Rating Scale Cornell Depression Scale
Carried out by a trained nurse
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Domain
Domain
Components
Assessment tools
Comments
social status
marital status, presence of a spouse or partner circle of communication and social contacts living conditions financial opportunities work activity, profession education the opportunity to engage in familiar activities cleaning the house, cooking, shopping for groceries, etc. care needs and preferences of patients related to care loss of loved ones, stresses that have happened in life, psychological problems, the ability to cope with them and with psychological problems alcohol abuse, drug addiction in relatives, people around the patient religiosity cruel treatment household safety
May be performed by a nurse. A detailed assessment is carried out by a social work specialist involved in a comprehensive geriatric assessment
Based on a comprehensive geriatric assessment, the geriatrician develops an individual management plan for a patient with senile asthenia, which recommends the inclusion of recommendations on the following items:
physical activity,
food,
cognitive training,
additional laboratory and instrumental examinations, consultations
of specialists in accordance with the identified geriatric syndromes and conditions that affect the course of senile asthenia,
correction of identified geriatric syndromes and goal-oriented treatment of the patient's chronic diseases. Neurologists, cardiologists, endocrinologists, clinical pharmacologists, nutritionists, rheumatologists, urologists, obstetricians can be involved as consultants, if necessary, for the purpose of dynamic monitoring of the patient in the multidisciplinary
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team gynecologists, otorhinolaryngologists, audiologists, ophthalmologists, traumatologists-orthopedists, physiotherapists and medical rehabilitation specialists, etc.,
optimization of drug therapy taking into account STOPP/START criteria with a consultation with a clinical pharmacologist, if necessary, and also, if necessary, assistance in taking medications (assistance in purchasing medications, use of pillboxes, direct control of medications, etc.),
the use of means and methods that adapt the environment to the patient's functional capabilities and/or the patient's functional capabilities to the environment (mobility, cane, walker, joint prosthetics and orthotics, glasses, hearing aid, etc.),
organization of a safe life,
direction for rehabilitation activities,
the level of need for social assistance and long-term care that can be
provided by social services and, depending on the situation, the need for medical patronage and palliative care can be assessed.
Whenever possible, a discussion of the individual management plan should be held with the patient and/or relatives/carers to ensure that the plan is in line with the patient's goals and priorities and to ensure that the family/carers are involved in its implementation. It is recommended to communicate an individualized patient management plan with frailty, directly observing the patient (district physician, general practitioner, family doctor), in order to ensure joint successive long-term follow-up. An individual plan for managing a patient with senile asthenia is carried out by a doctor directly observing the patient, together with a geriatrician. An individual patient management plan may be revised based on the results of monitoring the patient's functional status.
Scheduled repeated comprehensive geriatric evaluation of a patient with senile asthenia is recommended at least once every 12 months.
Unscheduled repeated comprehensive geriatric assessment is recommended in situations that significantly affect the functional state of the patient (for example, fractures, acute cerebrovascular accident,
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oncological disease, acute disease with a long period of convalescence (pneumonia), surgical treatment).
In patients with acute functional disorders, in order to establish their cause and determine management tactics, it is necessary to conduct a thorough analysis of the clinical and social situation, exclude acute/exacerbation of chronic diseases, fractures of the femur, thoracic/lumbar spine, and depression.
It must be remembered that:
recommended to perform a comprehensive geriatric assessment before carrying out diagnostic and other measures according to clinical guidelines for a suspected/previously diagnosed disease (if this disease/condition is not acute and/or life-threatening) in patients with highly probable senile asthenia in order to determine management tactics based on the whole patient- oriented approach. If it is not possible to conduct a comprehensive geriatric assessment by a multidisciplinary geriatric team, the management of a patient with senile asthenia syndrome by a general practitioner, family doctor and specialist doctors should be based on a holistic approach to assessing his needs and in cooperation with a geriatrician.
recommended to perform a comprehensive geriatric assessment of elderly patients before performing elective surgical interventions, deciding on the tactics of treating oncological and other diseases in order to determine the benefit/risk ratio of the intervention, predicting possible changes in the functional status of the patient and his needs for assistance and care, as well as planning volume of rehabilitation measures.
It is recommended to carefully collect and analyze the drug history in all patients 60 years of age and older in order to identify polypharmacy and irrational prescribing of drugs using STOPP/START the criteria presented in the Guidelines “Pharmacotherapy in the elderly and senile age. Careful analysis of the drug history and detection of polypharmacy is necessary for all patients of elderly and senile age and is especially important in patients with a high probability of frailty. In elderly and senile patients, the risk of adverse drug reactions is significantly increased. The
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presence of polymorbidity, observation by different specialists leads to polypharmacy. Polypharmacy is associated with an increased risk of adverse outcomes (progression of frailty, cognitive impairment, falls, dependence on outside help, death). It is necessary to find out the list of actually taken drugs (name, dose, multiplicity, route of administration, duration of administration), including over-the-counter drugs, herbal remedies and dietary supplements. If possible, ask the patient (relatives/guardians/ caregivers) to show the medications taken, ask the patient to bring to the visit all the drugs that he takes. It is imperative to assess the patient's ability to independently take medications, paying attention to the state of cognitive functions, the preservation of hand functions, visual acuity and motivation.
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6. LABORATORY RESEARCH
In view of the non-specific manifestations of frailty , the possibility of the occurrence/aggravation of functional disorders in an elderly person against the background of an acute or exacerbation of a chronic disease, the possibility of an atypical picture of diseases, in the course of a comprehensive geriatric assessment, a complex of laboratory and instrumental studies should be performed to diagnose/differential diagnosis of conditions, potentially affecting the course of frailty and/or having similar clinical manifestations, including anemia, heart failure, diabetes mellitus, chronic kidney disease, liver and thyroid dysfunction, electrolyte disturbances, etc. Performing part of the examination before referring the patient to a consultation with to a geriatrician will reduce the number of visits of a patient with frailty to a medical institution, and will contribute to a faster and better implementation of a comprehensive geriatric assessment and the development of an individual management plan.
Necessary:
Determination of serum creatinine with the calculation of the glomerular filtration rate in all elderly and senile patients, especially those with a high probability of senile asthenia, to assess the functional state of the kidneys and select a dosing regimen for drugs.
General blood analysis. To assess the presence of anemia in patients referred for a comprehensive geriatric assessment, in view of its high prevalence in patients with senile asthenia, close association with other geriatric syndromes and high value for predicting the course of senile asthenia and the patient's life.
The level of thyroid-stimulating hormone in the blood due to the high prevalence of thyroid dysfunction in patients with senile asthenia, its close association with other geriatric syndromes (cognitive decline, decreased mobility) and the prognosis of the course of senile asthenia.
The level of total protein and blood albumin in order to identify malnutrition syndrome and predict the risk of progression of senile asthenia.
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The level of vitamin B12 in the blood in patients with cognitive impairment identified during a comprehensive geriatric assessment to assess potentially modifiable causes and determine treatment tactics.
The level of 25(OH) vitamin D in the blood in patients diagnosed with senile asthenia in order to select the optimal dosing regimen for vitamin D and its analogues.
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7. INSTRUMENTAL DIAGNOSTIC STUDIES
In patients with a high probability of frailty, it is recommended to assess the state of previously diagnosed chronic diseases, as well as differential diagnosis between frailty and diseases with similar clinical manifestations using the necessary instrumental treatment. At the same time, the scope of the examination is determined taking into account the results of a comprehensive geriatric assessment, the doctor's clinical judgment about the patient's life expectancy and personalized treatment goals. When deciding whether to conduct a diagnostic search or examination for a chronic disease, one should take into account the contribution of this condition/disease to the progression of the frailty syndrome, take into account the tolerability and potential risks associated with the performance of the examination, and the impact of the results of the examination on further management of the patient in the context preservation of functional activity and quality of life. The volume of diagnostic measures in patients with senile asthenia may be incomplete in relation to clinical recommendations for this condition.
Lateral X-ray examination of the thoracic and lumbar spine (Th4- L5) is recommended in patients with senile asthenia with a high risk of fractures according to FRAX, a high risk of falls, with back pain, a decrease in height > 4 cm compared with younger age or > 2 cm with regular medical examination, taking glucocorticoids, with type 2 diabetes mellitus, with diagnosed fractures of another localization in order to actively detect compression fractures of the vertebral bodies.
It is recommended to perform studies aimed at identifying the causes of falls associated with transient hypoperfusion of the brain (hemodynamically significant stenosis of the carotid arteries, aortic valve stenosis, hemodynamically significant disturbances in heart rhythm and conduction), osteoporosis and pathology of the musculoskeletal system, pathology of the central and peripheral nervous system, if necessary, resorting to consultations of specialized specialists, in patients with falls for
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the purpose of differential diagnosis and development of an individual management plan.
It is recommended to perform studies aimed at identifying chronic cerebrovascular insufficiency and/or previous cerebrovascular accidents, atrophic processes in the brain (including determining the volume of the hippocampus ), brain tumors/metastases, normotensive hydrocephalus, as well as consulting a neurologist for advanced neuropsychological testing in patients with cognitive impairments identified during a comprehensive geriatric assessment, in order to clarify the nature and severity of cognitive disorders and the selection of specific therapy.
Consultation with a psychologist/psychotherapist/psychiatrist is recommended for patients diagnosed with depression during a comprehensive geriatric assessment in order to clarify the diagnosis and include appropriate treatment measures in an individual management plan.
recommended to consult a urologist (for women a urologist and an obstetrician-gynecologist) in patients with identified urinary incontinence syndrome to include appropriate diagnostic and treatment measures in an individual management plan.
It is recommended to perform the following studies in patients with senile asthenia and malnutrition syndrome in order to identify the causes and determine management tactics:
a thorough assessment of the condition of the oral cavity, if necessary, with a referral for consultation and treatment to a dentist (dental treatment, selection of prostheses, etc.);
conducting an examination to exclude diseases of the esophagus, stomach, duodenum, if necessary, using less invasive research methods (for example, fluoroscopy of the esophagus and stomach with a barium mixture);
if necessary consultation of a dietitian, organization of social assistance (purchase of products, cooking, feeding).
It is recommended to conduct a thorough analysis of the clinical situation and its causes (pain, constipation, acute urinary retention, bleeding, acute infectious disease, acute kidney injury, acute cerebrovascular accident, etc.) in patients with the development of geriatric delirium.