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BIOMARKERS AS TARGETED
HERBAL DRUG DISCOVERY
A Pharmacological Approach to
Nanomedicines
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BIOMARKERS AS TARGETED
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HERBAL DRUG DISCOVERY
A Pharmacological Approach to
Nanomedicines
Edited by
Mahfoozur Rahman, PhD
Sarwar Beg, PhD
Mazin A. Zamzami, PhD
Hani Choudhry, PhD
Aftab Ahmad, PhD
Khalid S. Alharbi, PhD
First edition published 2022
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Apple Academic Press Inc.
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Library and Archives Canada Cataloguing in Publication
Title: Biomarkers as targeted herbal drug discovery : a pharmacological approach to nanomedicines / edited by Mahfoozur
Rahman, PhD [and ve others].
Names: Rahman, Mahfoozur, 1984- editor.
Description: First edition. | Includes bibliographical references and index.
Identiers: Canadiana (print) 2021010953X | Canadiana (ebook) 2021010970X | ISBN 9781771889025 (hardcover) |
ISBN 9781003045526 (ebook)
Subjects: LCSH: Herbs—Therapeutic use. | LCSH: Biochemical markers. | LCSH: Nanomedicine. | LCSH: Alternative
medicine.
Classication: LCC RS160 .B56 2021 | DDC 615.3/21—dc23
Library of Congress Cataloging‑in‑Publication Data
CRC Press
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2 Park Square, Milton Park,
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ISBN: 978-1-77188-902-5 (hbk)
ISBN: 978-1-77463-787-6 (pbk)
ISBN: 978-1-00304-552-6 (ebk)
CIP data on le with US Library of Congress
About the Editors
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Mahfoozur Rahman, PhD
Assistant Professor, Department of Pharmaceutical
Sciences, Faculty of Health Science, Sam
Higginbottom University of Agriculture,
Technology & Sciences (SHUATS), Allahabad, India
Mahfoozur Rahman, PhD, is an Assistant Professor in
the Department of Pharmaceutical Sciences, Faculty
of Health Science, Sam Higginbottom University of
Agriculture, Technology and Sciences (SHUATS), Allahabad, India. His
major areas of research interest include development and characterization
of nanosized drug delivery systems for inflammatory disorders, including
psoriasis, arthritis, neurodegenerative disorders, cancer, etc. In addition, he
is also working on amalgamation of herbal medicinal plants with modern
therapeutics in order to deliver scientifically acceptable therapies for various
diseases management. To date he has published over 130 publications in
peer-reviewed journals, such as Seminar in Cancer Biology, Drug Discovery
Today, Nanomedicine, etc. He has also published 40 book chapters, five
international books, and three articles in international journals. Overall,
he has earned highly impressive publishing and citation record in Google
Scholar (H-index of 28 and total citation over 2000 to date). Dr. Rahman has
received travel grants from various international congresses, such as IAPRD,
MDS, Nano Today Conference, KSN 2019, etc. He is also serving as an
editorial board member and guest editor for several journals.
Sarwar Beg, PhD
Assistant Professor, Department of Pharmaceutics,
School of Pharmaceutical Education and Research,
Jamia Hamdard, New Delhi, India
Sarwar Beg, PhD, is an Assistant Professor in the
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New
vi About the Editors
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Delhi, India. He has over a decade of teaching and research experience in the
field of pharmaceutics and biopharmaceutics, especially in the development
of novel and nanostructured drug delivery systems using Quality-by-Design
paradigms. Before joining Jamia Hamdard, Dr. Beg worked as a Research
Scientist at Jubilant Generics Limited, Noida, India. He has authored over
150 publications, 48 book chapters, 10 books, three Indian patent applications and served as a guest editors of several international journals. He has a
Google Scholar H-Index of 26 and over 2800 citations to his credit.
Mazin A. Zamzami, PhD
Associate Professor in Clinical Biochemistry,
Chairman of the Biochemistry Department,
Faculty of Science at King Abdulaziz University,
Jeddah, Kingdom of Saudi Arabia
MazinZamzami, PhD, is an Associate Professor in
Clinical Biochemistry and the Chairman of the Biochemistry Department,
Faculty of Science at King Abdulaziz University, Jeddah, Kingdom of
Saudi Arabia. Dr. Zamzami joined the KAU family in 2002 as a Lecturer in
Biochemistry in the Faculty of Health Sciences. Previously, Dr. Zamzami
directed the Serology Department as well as worked as a senior laboratory
technician in the Clinical Biochemistry Department at Al-Thagher Hospital,
Jeddah, Saudi Arabia, for approximately five years. His clinical research
interest is in the molecular basis of disease, particularly nucleotide metabolic
diseases, and pharmacogenetics. He has several published articles and has
presented papers at international and national scientific conferences.
genesis Unit at the King Fahd Center for Medical Research at King Abdulaziz
University (KAU), Saudi Arabia. He is also a Visiting Assistant Professor
Hani Choudhry, PhD
Assistant Professor of Cancer Genomics and the
Head of Cancer and Mutagenesis Unit at the King
Fahd Center for Medical Research in King Abdulaziz
University (KAU), Saudi Arabia
Hani Choudhry, PhD, is an Assistant Professor of
Cancer Genomics and the Head of Cancer and Muta-
vii About the Editors
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at the NIH Center of Excellence in Genomic Science, Center for Personal
Dynamic Regulome, School of Medicine, Stanford University, California,
USA. Dr. Choudhry has received a number of international and prestigious
awards, including two AACR Scholar-in-Training Awards, the Susan G.
Komen for the Cure Award and Proffered Paper Award for Non-coding RNA
in Cancers at the EACR Annual Meeting. He has published over 40 research
articles in high-impact and respected scientific journals.
Aftab Ahmad, PhD
Associate Professor of Pharmacology,
Health Information Technology Department,
Jeddah Community College, King Abdulaziz University,
Jeddah, Kingdom of Saudi Arabia
Aftab Ahmad, PhD, is an Associate Professor of
Pharmacology in the Health Information Technology
Department at Jeddah Community College of King Abdulaziz University,
Jeddah, Kingdom of Saudi Arabia. He had completed numerous research
projects as a principle investigator (PI) funded by the deanship of scientific
research (DSR) of King Abdulaziz University. He has contributed more than
100 full-length research articles to reputable national and international journals and is also an expert reviewer for several journals. His current h-index
is 13, and he has been cited over 1,400 times to date.
Pharmacology and Toxicology and the Head of the Pharmacology Department, College of Pharmacy at Jouf University, Sakaka, Saudi Arabia. He
obtained both his BSc (Pharmaceutical Sciences, 2002) and MSc (Toxicology, 2009) from the College of Pharmacy at King Saud University (KSU),
Riyadh, Saudi Arabia. He was awarded his PhD (Pharmacy and Biomedical
Sciences, 2016) from Stathclyde University, United Kingdom. Dr. Alharbi’s
Khalid S. Alharbi, PhD
Assistant Professor of Pharmacology and Toxicology;
Head of the Pharmacology Department,
College of Pharmacy, Jouf University, Sakaka,
Saudi Arabia
Khalid S. Alharbi, PhD, is an Assistant Professor of
major area of research is cancer including drug discovery, nanomedicine,
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and preclinical pharmacological and toxicological studies of anticancer
agents. He has published several articles in peer-reviewed journals and has
presented papers at numerous international conferences.
Contents
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1. Inammatory Biomarkers: An Important Tool for
Mahfoozur Rahman, Ankit Sahoo, Mohammad Atif, and Sarwar Beg
2. Herbal Anti-Arthritic Drug Discovery Tool Based on
Mahfoozur Rahman, Ankit Sahoo, and Sarwar Beg
3. Curcumin Nanomedicine and Their Application in the
Sadaf Jamal Gilani, Syed Sarim Imam, Mohammed Jafar, Sultan Alshehri,
Md. Taleuzzaman, and Mohammed Asadullah Jahangir
4. Ursolic Acid: A Pentacyclic Triterpene from Plants
Monalisha Sen Gupta, Md. Adil Shaharyar, Mahfoozur Rahman,
Kumar Anand, Imran Kazmi, Muhammad Afzal, and Sanmoy Karmakar
Sabya Sachi Das, P. R. P. Verma, and Sandeep Kumar Singh
Kumar Anand, Subhabrata Ray, Md. Adil Shaharyar, Mahfoozur Rahman,
Rudranil Bhowmik, Sanmoy Karmakar, and Monalisha Sen gupta
Mohammed Asadullah Jahangir, Abdul Muheem, Syed Sarim Imam,
Farhan Jalees Ahmed, and Mohd. Aqil
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