reduced long-term survival [13]. AL are associated with lon­ger lengths of stay and increased intensive care unit admis­sion, incurring additional annual costs of £1.1–35 million in the United Kingdom alone [14]. The additional cost per patient with AL is between £3372 to £10,901 (approximately 4777–15,443 USD). Despite advances in perioperative care and surgical technique, the risk of anastomotic leak is still up to 19% in colorectal anastomosis [15]. For anterior resection of the rectum, the perfusion of the left colon and anastomosis is most commonly reliant on the marginal artery. Inadequate bowel perfusion is widely regarded as the most common contributing factor for AL through ischaemia [16–18], pos­sibly caused by a failure in normal tissue regeneration. Traditional assessment of colonic extremity perfusion is per­formed through a combination of the detection of palpable pulses in the mesentery, absence of bowel discolouration, and pulsatile bleeding from the cut ends of the anastomosis. Using an intravenous injection of ICG is a more objective method of perfusion assessment and may be used at different timepoints during bowel transection and subsequent anasto­mosis, e.g., following inferior mesenteric artery ligation and/ or following anastomotic construction. Fluorescence emis­sion occurs only in the perfused bowel, whereas a notorious absence of uorescence is present in non-perfused areas of the colon.