Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:
Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_992_Библиотеки_им_академика_М_И_Перельмана.pdf
Скачиваний:
0
Добавлен:
31.08.2026
Размер:
27 Мб
Скачать
Index
Gallbladder cancer 232–238
adjuvant therapy 237 clinical presentation/diagnosis 233–234 epidemiology/aetiology 232–233, 233f histopathology/staging 234, 234t, 235t palliation 237–238 surgical approach, aggressive 235 surgical therapy 235–237
post-cholecystectomy malignancy 236–237 suspected malignancy 236 T1 tumours 236 T2 tumours 236 T3 tumours 236 T4 tumours 236 unsuspected malignancy 236–237
Gallstones 174–195
acalculous biliary pain 190–192 acute pancreatitis 244, 246 asymptomatic 178–179 common bile duct (CBD) stones 183–190 composition/formation/risk factors 174–175, 175f gallbladder stones 178–183 investigation 176–178
blood tests 177 computed tomography (CT) 177 endoscopic retrograde cholangiopancreatography
(ERCP) 178, 178f endoscopic ultrasound (EUS) 177 magnetic resonance cholangiopancreatography
(MRCP) 178 percutaneous transhepatic cholangiography (PTC) 178 radioisotope scanning 177–178 ultrasonography 177
management 251 operative treatments 179
cholecystostomy 181 common bile duct (CBD) injury 181, 182–183, 182f, 183f endoscopic retrograde cholangiopancreatography
(ERCP) 187–190, 188b, 188f intraoperative cholangiography (IOC) 181–182 laparoscopic cholecystectomy 180–181 laparoscopic choledochotomy 187, 187b laparoscopic transcystic common bile duct (CBD)
exploration 184f, 185, 185f, 187b laparoscopic ultrasound (LUS) 183 mini-laparotomy cholecystectomy 180 open cholecystectomy 179–180 open choledochotomy 187 recurrent common bile duct (CBD) stones 190 subtotal cholecystostomy 181
non-operative treatments 179
dissolution agents 179 lithotripsy 179
presentation 175–176 Gastric outlet obstruction 257 Gastric varices
classification 149t
therapy 152–154 Gastrinoma 296t Gastroduodenal artery 36–37 Gastrointestinal (GI) tract
adenocarcinoma 139–140
haemorrhage 256–257
outflow obstruction, upper 284–285
stromal tumours (GISTs) 136–137 Gastrointestinal Study Group (GITSG) 285
GLOBOCAN series (IARC) 80 Glucagonoma syndrome 296t γ-Glutamyl transpeptidase (GGT) 177 Glutathione synthesis (GSH) 7, 10 GRETCH staging system 91
H
Haemangiomas 60–64, 168
clinical presentation 61–63, 62f, 63f management 63–64
pathology 60–61, 61f Haemophilus influenzae 284 Haemopoetic (haematopoietic) stem cell therapy 14–15 Haemorrhage
acute pancreatitis 256, 256f
gastrointestinal (GI) 256–257
variceal 149–152, 151f, 153f, 155 Hamburg procedure 269, 269f Hemihepatectomy, defined 18f, 20–21 HepatAssist device 13 Hepatectomy 22, 93
defined 18f, 20–21
repeat 116
two-stage 116 Hepatic arterial infusion (HAI) 124 Hepatic arteries
anatomy 17–20, 18f, 19f, 20f
resection 21–22, 21f
ligation 314 Hepatic dysfunction see Liver failure; Liver function Hepatic injury scale 305t Hepatic insufficiency, liver resection 2–3 Hepatic progenitor cells (HPCs) 9–10 Hepatic pseudotumours 68 Hepatic steatosis 11, 11f
assessment 11, 11f Hepatic veins
acute Budd–Chiari syndrome 158
anatomy 25f, 26–27, 26f
invasion, macroscopic 100 Hepatic venous pressure gradient (HVPG) 149, 150 Hepatic venous thrombosis see Budd–Chiari syndrome Hepatitis, autoimmune 83 Hepatitis B virus (HBV) 80, 81–82
see also Hepatocellular carcinoma (HCC) Hepatitis C virus (HCV) 80, 82
see also Hepatocellular carcinoma (HCC) Hepatitis D virus (HDV) 82 Hepatitis E virus (HEV) 82 Hepatobiliary scintigraphy 6 Hepatocellular adenoma (HCAs) 84 Hepatocellular carcinoma (HCC) 42–44, 80–100, 210f
biliary injury 209, 210f
clinical presentation 85–86, 86f
diagnosis 89–90
histological assessment 89
incidence 80–81, 81t
laparoscopy/laparoscopic ultrasound (LUS) 43
liver function tests 86
natural history/staging 90–91, 91t
pathology 84–85, 85f
radiological studies 86–89
accuracy 89 angiography 89
331
Index
Hepatocellular carcinoma (HCC) (Continued)
computed tomography (CT) 42–43, 87 contrast-enhanced ultrasound (CEUS) 88–89 magnetic resonance imaging (MRI) 42–43, 87–88 positron emission tomography (PET) 89
ultrasound 87 resectability, staging/assessment 40f, 43–44, 43t risk factors 81–84 screening 91–92 serum tumour markers 86 transabdominal ultrasound 42, 42f treatment 92–99
complicated HCC 99–100
uncomplicated HCC 100
ablation see Percutaneous local ablative therapy
chemoembolisation see Transarterial
chemoembolisation (TACE) normal livers 92–93 palliative 98–99 resection see under Liver resection strategy, defining 99–100 transplantation see Liver transplantation (LT)
variant, fibrolamellar carcinoma (FLC) 100
Hepatolithiasis 211, 219
management 211
Hepato-pancreato-biliary (HPB) malignancy see
Colorectal liver metastases (CRLMs);
Hepatocellular carcinoma (HCC); Pancreatic/
periampullary carcinoma; Proximal bile duct tumours
Hereditary chronic pancreatitis (HCP) 263 Hereditary haemochromatosis (HH) 83 Hereditary pancreatic cancer 276 Hereditary spherocytosis 167 Hilar cholangiocarcinoma 219–220, 221–229
adjuvant therapy 227 classification 223–224, 224b, 224t clinical presentation/diagnosis 221–222 palliation 227–229
chemotherapy 229 intrahepatic biliary-enteric bypass 228 percutaneous biliary drainage 228 photodynamic therapy 228 radiation therapy 228
preoperative evaluation 223–225, 223f radiological investigation 222–223
computed tomography (CT) 222 direct cholangiography 222 duplex ultrasonography 222, 222f magnetic resonance cholangiopancreatography
(MRCP) 223, 223f
resection 223f, 225–226, 225f, 225t, 227t
results 226–227
T-stage criteria 224t
treatment options 225 Hilar marginal artery 32, 33f Hjortsjo’s crook 23, 23f Hodgkin’s lymphoma 167 Human immunodeficiency virus (HIV) infection 82 Hydatid cyst 71–73, 72f
clinical presentation 71–72
management 72–73 Hydatid sand 71 Hydrojet 117 Hydroxy-imino-diacetic acid (HIDA) 177–178 5-Hydroxyindoleacetic acid (5-HIAA) 136 Hyperamylasaemia 246
Hyperplasia, nodular regenerative 68 Hypertension
intra-abdominal (IAH) 247 portal see Portal hypertension
Hyperthermic intraperitoneal chemotherapy
(HIPEC) 138
I
Iatrogenic biliary injury 199–209
aetiology 199 avoiding, techniques 199–201, 200f classification 201, 201t, 202f management 203–209, 204f
biliary fistula 203–204 biliary obstruction 204–205 complications 206f, 208–209, 209f operative techniques 207–208 prognosis 209 repair, timing 205–207, 205f, 206f, 207f vascular injury 206, 206f, 207f
presentation 201–203 Imatinib 136–137 Immune thrombocytopenic purpura (ITP) 166–167, 168 Immunity, innate 8–9 Indocyanine green (ICG) 6, 6f Infection, prevention 250 Inferior vena cava (IVC) 17, 18–20, 18f, 114–115
acute Budd–Chiari syndrome 158
hepatic veins and 26–27
liver capsule and 29–30 Inferior vena caval ligament 27 Inflammatory response, inhibition 251 Innate immunity, liver resection 8–9 Insulinoma 296t International Agency for Research on Cancer (IARC) 80,
275–276
International Association of Pancreatology (IAP)
292–293, 292b, 294
International Classification of Diseases for Oncology
(ICD) 101
International Symposium on Acute Pancreatitis, Atlanta
Conference 244–245 Intra-abdominal hypertension (IAH) 247 Intraductal papillary mucinous neoplasms (IPMNs) 277,
289–295
clinical presentation 289–290 investigations 290–291, 290f, 291t management 292–294 outcome 294–295, 294t
pathology 291–292, 292f Intrahepatic biliary-enteric bypass 228 Intrahepatic cholangiocarcinoma (ICCA) 80, 100–103
classification/staging 101
clinical presentation 102
diagnosis 102
imaging studies 102, 102f, 103f
incidence 101
pathology/progression 101–102
risk factors 101
treatment 102–103 Intraoperative cholangiography (IOC) 181–182 Irinotecan 120
-based regimes 120–121, 122, 123, 124
Ischaemia/reperfusion (I/R) injury 3, 10
332
Index
J
Jarnagin–Blumgart clinical T staging system 52–53,
53t
Jaundice, obstructive 284
see also Parasitic infestation, jaundice
Johns Hopkins-Mayo Clinic Collaborative Study 285
K
Karnofsky index 90 Kasai’s operation (porto-enterostomy) 196, 208 Kausch–Whipple procedure 268 King’s College Hospital, acute liver failure criteria 1 Klatskin tumours, classification 53f Klebsiella spp 221 Kocher manoeuvre 320 Kocherisation 283 KRAS proto-oncogene 120, 121, 122 Kupffer cells 1
L
Laparoscopic surgery 117–118 Laparoscopic ultrasound (LUS)
colorectal liver metastases (CRLMs) 41, 112–113 gallstones 183 hepatocellular carcinoma (HCC) 43 pancreatic/periampullary carcinoma 46–47, 47f
proximal bile duct tumours 51 Laparotomy, open 254–255 Left adrenal gland 36 Left lateral sectional bile duct 23–24, 23f Leucovorin 122
see also FOLFOX Lidocaine (MEG-X) 6 Lithotripsy 179 Liver
lesions see Benign liver lesions
metastases see Colorectal liver metastases (CRLMs);
Non-colorectal hepatic metastases
tumours see Primary malignant tumours, liver Liver abscess 69–70, 70f
clinical presentation 69
management 69–70 Liver, anatomy 17–30
overview 17–21
hepatic artery 17–20, 18f, 19f, 20f resectional terminology 18f, 19f, 20–21, 20f
resections 21–30
bile ducts 22–24, 22f, 23f hepatic arteries 21–22 hepatic veins 25f, 26–27, 26f plate/sheath system 28–30, 28f, 29f portal veins 24–26, 24f, 25f
Liver Cancer Study Group of Japan (LCSGJ) 90, 91t, 94,
101, 220–221
Liver cell adenoma 64–65
clinical presentation 65
management 65, 66f
pathology 64–65, 64f Liver cysts, simple 73–74
clinical presentation 73–74, 73f
management 74 Liver Dialysis Device 13
Liver failure 1–16
future developments 14–15 symptoms 1–5, 2b
acute 2–3, 5t chronic 3, 3t, 5t
therapy 13–14
artificial support 13–14 extracorporeal support 13 N-acetyl cysteine 13 nutritional support 13 stem cell 14–15
transplantation (LT) 14 Liver flukes (trematodes) 211–212 Liver function 1–16
blood tests 5, 5t future developments 14–15 metabolic 3–4 overview 1 substance clearance tests 5–12 tests (LFTs) 177, 184 volume measurement 4–5, 4f, 5f
Liver regeneration 9
cell populations 9–10 molecular signals 9, 10f
Liver resection 208–209, 209f
anatomical 314 blood flow, effect on 8, 8f chemotherapy 11 consequences 10 hepatocellular carcinoma (HCC) 93–98
limitations 93
outcome 94
recurrence, treatment 94–95
risks/patient selection 93–94
technique 94
innate immunity 8–9 resectional debridement 314, 314f small-for-size syndrome 10–11 surgical anatomy see under Liver, anatomy
Liver transplantation (LT) 14, 95–96, 157, 208–209
patient selection 95 portal hypertension 157 rationale 95 trauma 315 treatment 95–96
Liver trauma 304–316
classification 305, 305t complications 315–316
non-operative management 315
outcome 316
postoperative 315–316
diagnosis 305–308, 307f mechanisms of injury 304–305 operative management 309–315
anatomical resection 314
ex vivo surgery/liver transplantation (LT) 315
haemostasis, techniques 313, 313f
hepatic artery ligation 314
hepatic venous/retrohepatic caval injury
314–315 incision 309–310 intraoperative assessment 310–311, 310f, 311f perihepatic packing 311–313, 312f resectional debridement 314, 314f strategy 309
non-operative management 308–309, 315
333
Index
LiverMetSurvey group 122 Living-donor liver transplantation (LDLT) 95 Longitudinal pancreatico-jejunostomy 268 Lung cancer 141 Lymphoma 105, 167 Lymphoplasmacytic sclerosing pancreatitis 213
M
Macroregenerative nodules 68 Magnetic resonance cholangiopancreatography (MRCP)
acute pancreatitis 248–249 biliary disorders 205, 206–207, 229 cholangiocarcinoma 222 choledochal cysts 197 computed tomography (CT) 177 gallstones 178 hepatolithiasis 211 hilar cholangiocarcinoma 223, 223f Mirizzi’s syndrome 210 primary sclerosing cholangitis 212–213
Magnetic resonance imaging (MRI)
acute pancreatitis 248–249, 249f colorectal liver metastases (CRLMs) 40, 110–112 hepatocellular carcinoma (HCC) 42–43, 87–88 pancreatic/periampullary carcinoma 45, 45f proximal bile duct tumours 50–51
Malignancy
biliary see Biliary tract, malignancy choledochal cysts 197, 197f primary sclerosing cholangitis 213 see also Colorectal liver metastases (CRLMs);
Hepatocellular carcinoma (HCC); Pancreatic/
periampullary carcinoma Marginal arteries 32, 33f MARS (Molecular Absorbent Recirculating System)
device 13 Marseille Classification, chronic pancreatitis (CP) 260 Masitinib 137 Melanoma 139 MELD (Model for End-stage Liver Disease) score 6, 93,
95–96, 147–148, 148b, 157 Memorial Sloan–Kettering Cancer Center (MSKCC) 222,
226–227, 228, 230, 231, 235
clinical risk score (CRS) 112–113
staging system 52–53 Meningococcus C 284 Mesenchymal tumours, classification 60b Metabolic liver disease 83–84 Metabolic liver function 3–4 Metastasectomy 140–141 Microwave ablation (MWA) 125 Milan criteria 95–96 Milano/Mazzaferro criteria 43–44 Mirizzi’s syndrome 209–211, 210f
management 210–211
presentation 210 Mixed mesenchymal/epithelial tumours, classification 60b Molecular signals, liver regeneration 9, 10f Monoethylglycinexylidide (MEG-X) 6 Mucinous cystic neoplasm (MCN) 277, 289, 292,
299–301 Multidisciplinary team (MDT) approach 125–126 Multiple organ dysfunction syndrome, defined 245b Myeloid disease 168
N
N-acetyl cysteine 13 National Institute for Health and Clinical Excellence
(NICE) 120–121 Near-infrared spectroscopy 8 Necrosectomy, methods 254–256, 254f Necrosis 253–256
infected 254–256 minimally invasive approaches 255–256
percutaneous drainage 255
surgery 255–256, 256f necrosectomy, methods 254–256, 254f open laparotomy/debridement 254–255, 254f sterile 253–254
Neuroendocrine tumours (NETs) 132, 134–136, 135f, 136f Nilotinib 137 Nitrogen homeostasis 3–4 Nitrogen metabolism 4 ‘No-touch’ technique 226 Nodular regenerative hyperplasia 68 Non-alcoholic fatty liver disease (NAFLD) 82–83 Non-colorectal hepatic metastases 132–145
adrenocortical tumours 141 breast cancer 137 clinical approach 134 endometrial cancer 141 gastrointestinal (GI) adenocarcinoma 139–140 gastrointestinal (GI) stromal tumours (GISTs)
136–137 lung cancer 141 melanoma 139 neuroendocrine tumours (NETs) 132, 134–136, 135f,
136f ovarian cancer 137–138, 138f pathophysiology 133 renal cell carcinoma (RCC) 138–139 testicular cancer 140–141 treatment 134 urothelial cancer 141
Non-colorectal non-neuro-endocrine gastrointestinal (GI)
metastases 140b, 141
Non-Hodgkin’s lymphoma 167 Norfloxacin 152b Nutritional support 250–251
delivery 250 disease modulation 250–251 liver failure 13
O
Obstructive jaundice 284 Occupation, risk factor 276 Octreotide 152–154 Oesophageal cancer 139–140 Oesophageal varices
classification 149t management 148–149 therapy 149–152, 149t
Oliveira classification system 53t OncoSurge computer model 126 Open laparotomy/debridement
closed lavage 255 drainage/closed packing 254 open packing 255
334
Index
Opisthorchis viverrini 101, 219 OPUS trial 121 Ovarian cancer 137–138, 138f Oxaliplatin 120
see also FOLFOX
P
Paclitaxel 138 Palliation
gallbladder cancer 237–238 hilar cholangiocarcinoma 227–229 pancreatic adenocarcinoma 284–285
Pancreas
cancer, hereditary 276 enzymes, inhibition 251 secretion, inhibition 251 tumours 246
Pancreas, anatomy 34–37
blood supply 34–35, 35f ligaments 36–37 lymphatics 35, 36f pancreatic ducts 34
Pancreatectomy
central 284 distal 268, 284 laparoscopic 284 total 267, 284
Pancreatic abscess 256
defined 245b
Pancreatic adenocarcinoma 275–288
epidemiology 275 future trends 285–286 investigations 278–280
cytology/histology 280 diagnosis 279–280 imaging 279–280, 279f markers 278
serology 278 pathology 281 precursor lesions 277, 279f presentation 277–278, 278b risk factors 275–276, 276b
diet/alcohol 276
hereditary pancreatic cancer 276
occupation 276
past medical history 276
smoking 275–276 staging techniques 280–281
laparoscopy 280–281, 280f, 281f treatment 281–285, 282f, 282t
adjuvant therapies 285
neoadjuvant therapy 285
palliation 284–285
resection 281–284
Pancreatic duct
fistula 253 obstruction 244 stricture 246, 257
Pancreatic ductal adenocarcinoma (PDAC) 140 Pancreatic intraepithelial neoplasia (PanIN) 277 Pancreatic neuroendocrine tumours (PNETs) 295–299
clinical presentation 295 investigations 295–297
biochemical 295
radiology 295–297, 297f
Pancreatic neuroendocrine tumours (PNETs) (Continued)
metastatic disease 299 pathology/outcome 299 treatment 296t, 297–298, 298f
Pancreatic trauma 318–322
classification 319, 319f, 319t, 320f complications 321–322 diagnosis 318–319, 318f management
initial 320 operative 320–321
mechanisms of injury 318
Pancreatic/periampullary carcinoma 44–50
computed tomography (CT)/magnetic resonance
imaging (MRI) 45, 45f
endoscopic retrograde cholangiopancreatography
(ERCP) 45–46 endoscopic ultrasound (EUS) 46 laparoscopy/laparoscopic ultrasound (LUS) 46–47, 47f positron emission tomography (PET) 46 resectability, staging/assessment 47–50, 47t, 48t,
49t, 50f transabdominal ultrasound 44–45
Pancreatico-duodenectomy 268, 283 Pancreatico-jejunostomy, longitudinal 268 Pancreatitis
acute see Acute pancreatitis chronic see Chronic pancreatitis (CP)
Parasitic infestation, jaundice 211–212 Partington–Rochelle procedure 268–269 Percutaneous biliary drainage 228 Percutaneous ethanol injection (PEI) 97, 98 Percutaneous local ablative therapy 97–98
advantages/disadvantages 97–98 contraindications 98 indications 98 methods 98 technique 97
Percutaneous transhepatic cholangiography (PTC) 178,
206–207, 222
Perihilar cholangiocarcinoma 52, 52t Photodynamic therapy 228 Pneumococcus 284 POCHER study 122 Polycystic liver disease (PCLD) 74–75, 74f
clinical presentation 74, 75f management 74–75
Polyvinyl alcohol (PVA) 124 Porcelain gallbladder 233 Portal hypertension 146–163
acute pancreatitis 256–257 aetiology/pathophysiology 146–147, 147t ascites, management 157–158 Budd–Chiari syndrome 146–147,
158–159
acute 158–159
chronic 159 imaging 148 natural history 147–148, 148b, 148t non-cirrhotic 157, 159–160
portal vein thrombosis 159–160
segmental 159 pharmacological therapy 149–154
gastric varices 152–154
oesophageal varices 149–152, 149t
portal hypertensive gastropathy (PHG) 154
335
Index
Portal hypertension (Continued)
presentation 148, 149t second-line therapies 154–157
selection 157 surgical options 155–157, 156f transjugular intrahepatic portosystemic shunt (TIPS)
154–155, 157, 159–160 splenectomy 168 varices, management 148–149
Portal hypertensive gastropathy (PHG) 154 Portal pedicle 28 Portal vein embolisation (PVE) 11–12, 12f, 93–94,
116 technique 12, 12f
Portal veins
anatomy 24–26, 24f, 25f invasion, macroscopic 100 thrombosis 159
Porto-enterostomy (Kasai’s operation) 196, 208 positron emission tomography (PET)
colorectal liver metastases (CRLMs) 40–41, 40f, 110f,
112, 112f, 113f, 114f, 115f hepatocellular carcinoma (HCC) 89 pancreatic/periampullary carcinoma 46 proximal bile duct tumours 51
Preoperative clinical T staging system 52–53, 53t Primary biliary cirrhosis (PBC) 83 Primary malignant tumours, liver 80–108
angiosarcoma 104–105 epithelioid haemangioendothelioma (EHE)
103–104 fibrolamellar carcinoma (FLC) 100 lymphoma 105 see also Hepatocellular carcinoma (HCC); Intrahepatic
cholangiocarcinoma (ICCA)
Primary sclerosing cholangitis (PSC) 212–213, 219
aetiology 212 investigation 212–213 malignancy 213 management 213 presentation 212
Prometheus system 13 Protein metabolism 3 Proton-pump inhibitor (PPI) 154, 296t Proximal bile duct tumours 50–53
computed tomography (CT)/magnetic resonance
imaging (MRI) 50–51 endoscopic retrograde cholangiopancreatography
(ERCP) 51 laparoscopy/laparoscopic ultrasound (LUS) 51 positron emission tomography (PET) 51 resectability, staging/assessment 52–53, 52t, 53f, 53t transabdominal ultrasound 50
Pseudocysts 252–253
acute, defined 245b endoscopic drainage 252 percutaneous drainage 252 surgical drainage 252–253
Pseudotumours, hepatic 68 Pylorus-preserving pancreatico-duodenectomy (PPPDR)
283–284
Pyogenic liver abscess 70
Q
Quality of life, biliary injury 209
R
Radiation therapy 228 Radical antegrade modular pancreato-splenectomy
(RAMPS) 36 Radioembolisation 99 Radiofrequency ablation (RFA) 41, 125
gastric adenocarcinoma 140 liver tumours 97, 98 neuroendocrine tumours (NETs) 135–136
non-colorectal hepatic metastases 134 Radioisotope scanning 177–178 Remnant liver volume (RLV) 93–94 Renal cell carcinoma (RCC) 138–139 Replaced arteries 21–22
defined 21 Retropancreatic fat 36 Right anterior sectional bile duct (RASBD)
22, 22f, 23f Right hepatic duct 22 Right posterior sectional bile duct (RPSBD)
22, 22f, 23f
S
Schistosomiasis 146–147 Selective internal radiation treatment (SIRT) 125 Sengstaken–Blakemore tube 152–154 Sepsis, postsplenectomy 164–165 Serous cystadenoma (SCA) 298f, 299–301 Severe acute pancreatitis, defined 245b Shunts, portal systemic 155–157, 156f Sickle cell anaemia 167 Small-bowel adenocarcinoma (SBA) 140 Smoking 275–276 Society for Surgery of the Alimentary Tract (SSAT),
Patient Care Guidelines 165–166, 166b Somatostatin 134, 296t, 297–298 Somatostatinoma 296t Sorafenib 99 Sphincter manometric abnormalities 247 Splenectomy 164–173
complications 171 elective indications 166–168 postsplenectomy sepsis 164–165, 165b preparation 168 technique 168–171
laparoscopic 169–171, 169f, 170f open 168–169
trauma 165–166, 165t, 166b Splenic artery 36–37, 164 Splenic vein 164
thrombosis 147 Stem cell therapy 14 Stenosis, common bile duct (CBD) 271 Stent insertion 188–189, 188f Strasberg classification, biliary complications
201, 202f Streptococcus viridans 221 Sunitinib 134 Superior mesenteric artery (SMA) 31, 34–35, 36–37 Superior mesenteric vein (SMV) 35, 36–37 Surface anatomy, liver 30 Systemic inflammatory response syndrome,
defined 245b
336
Index
T
Teardrop sign 49–50 Terlipressin 152–154 Testicular cancer 140–141 Thallassaemias 167 TissueLink dissecting sealer 117 TNM staging system (AJCC)
ampullary carcinoma 48t cholangiocarcinoma 49t exocrine/endocrine tumours 47t gallbladder cancer 234, 234t, 235t hepatocellular carcinoma (HCC) 43–44, 43t hilar cholangiocarcinoma 52, 52t liver tumours 91t, 101 pancreatic neuroendocrine tumours (PNETs) 299 primary liver cancers 231
trauma 281, 282t Todani classification, modified 197, 198f Transabdominal ultrasound (TAUS) Transarterial chemoembolisation (TACE) 96–97, 98, 99,
99b, 100, 134, 135–136, 138 chronic liver disease 99, 100 contraindications 96 drug-eluting beads for (DEB-TACE) 124 efficacy 96–97 monitoring 96, 97f morbidity/mortality 96 technique 96
Transarterial embolisation (TAE) 134, 135–136 Transection technique 117 Transhepatic stone retrieval 190 Transjugular intrahepatic portosystemic shunts (TIPS)
ascites 158 Budd–Chiari syndrome 158, 159 portal hypertension 146, 152, 154–155, 157,
159–160 vs portal systemic shunts 155–157
Transplantation see Liver transplantation (LT) Trauma
acute pancreatitis 246 biliary tract see Extrahepatic biliary tract trauma liver see Liver trauma pancreatic see Pancreatic trauma
Trematodes 211–212 TRIBE trial 122 T-stage system, hilar cholangiocarcinoma 223–224,
224b, 224t
Tumours
adrenocortical 141 ampulla/pancreas 246 benign, classification 60b benign liver 68–69 bile duct see Proximal bile duct tumours carcinoid 296t cystic 298f, 299–301 endocrine 47t exocrine 47t
Tumours (Continued)
gallbladder 236 gastrointestinal stromal (GISTs) 136–137 Klatskin classification 53f liver see Primary malignant tumours, liver neuroendocrine (NETs) 132, 134–136, 135f, 136f pancreatic. see entries beginning Pancreatic pseudotumours 68
U
Ultrasound (US)
acute pancreatitis 248 duplex 222, 222f endoscopic see Endoscopic ultrasound (EUS) laparoscopic see Laparoscopic ultrasound (LUS)
transabdominal 50 Umbilical vein (UV) 26–27, 26f Union for International Cancer Control (UICC) staging
system 43t, 44
Upper gastrointestinal (GI) tract outflow obstruction
284–285 Urea synthesis 6–7 Urothelial cancer 141 Ursodeoxycholate (UDCA) 179
V
Variceal band ligation (VBL) 150 Variceal haemorrhage 149–152, 151f, 153f, 155 Vascular endothelial growth factor (VEGF) 120
receptors 99 Vascular injury, biliary repair 206, 206f, 207f Veno-occlusive disease 146–147 Verner–Morrison syndrome, PNETs 296t Video-assisted retroperitoneal debridement (VARD)
technique 255–256 VIPoma 296t Virchow’s node 278 Volvulus 168 Von Hippel–Lindau syndrome 298f, 299 V-shaped incision 269–270, 269f
W
Whipple procedure 283 Whipple’s triad syndrome 296t World Health Organization 90
Y
Yttrium-90 (Y-90) 125
Z
Zollinger–Ellison syndrome 296t
337