Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_5875_Библиотеки_им_академика_М_И_Перельмана

A conventional drug delivery system often results in underdosing or overdosing, lacking the ability to precisely tailor the dose regimen to an individual patient’s require­ment. In response to the challenges posed by existing drug delivery system methods, The American Society of Mechanical Engineers favors the term “additive manufac­turing”, which describes a process that has become very promising in the pharmaceut­ical industry, particularly in the area of customized medicine (Nukala et al., 2019). The construction of products with complex 3D structures using three- dimensional 3D printing technology, which is acknowledged as a transformative process, is possible using computer- aided design (CAD) models. This innovation typically involves the deposition of materials layer by layer on a built platform, offering a novel and precise approach to drug- delivery customization. In the pacing pharmaceutical advancements, the traditional drug delivery system persists, often leading to the pitfalls of underdosing and overdosing, failing to hit the precision required to cater to individual patient needs (Katakam et al., 2022). However, hope emerges on the horizon with transformative powder- additive manufacturing (Tian et al., 2021, Yang et al., 2017). Embracing its remarkable 3D printing prowess, it crafts intricate structures with an almost magical touch, all orchestrated by the melody of CAD models. With mesmerizing nesse, it lays down layer upon layer of materials on its build platform; bring forth a realm of customized drug- delivery possibilities with accuracy (Nukala et al., 2019). In the world of advancing pharmaceutical breakthroughs, an enchanting spectacle has unfolded with the USFDA bestowing its dazzling approval upon the mesmerizing concept of EB3D printing technology. More than 100 3D- printed medical products, including orthopaedic, cranial implants, dental restorations such as crowns and external pros­thesis, and surgical equipment, have received FDA approval. Additionally, it approved SPRITAM (levetiracetam), a 3D- printed medication that uses the Zip Dose technology to treat epilepsy (Katakam et al., 2015).