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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_832_Библиотеки_им_академика_М_И_Перельмана

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A. L. Shada
2 Classication
Paraesophageal hernias occur when the esophageal hiatus is disrupted causing pro­gressive migration of abdominal contents (often the gastric fundus, occasionally other adjacent organs) into the chest cavity. PEH is a disease of the diaphragm and/ or phrenoesophageal ligament and can be regarded separately from GERD which is a disease of the gastroesophageal valve. Similar to other muscular hernias (ie: groin hernias), enlargement of the hiatal defect leads to attenuation and atrophy of sur­rounding diaphragm muscle and thinning of the peritoneum. This creates a hernia sac. This sac includes an anterior component (made up of phrenoesophageal liga­ment plus abdominal peritoneum) and a posterior component (made up of phreno­esophageal ligament plus retroperitoneum and lesser gastric sac). The blood supply of the stomach within both the gastrohepatic omentum as well as the greater omen­tum also migrates upward as the hernia enlarges. Thinning out of the phrenoesopha­geal ligament, coupled with the intrathoracic negative pressure, can allow the stomach to progressively move up into the mediastinum. The stomach can create adhesions in the mediastinum that leads to incarceration of the stomach in a volvu­lized position and lead to outlet obstruction.
There are four types of hiatal hernias (Fig.1): sliding hiatal hernia (type I), and para-esophageal hernias types II, III and IV.Sliding hiatal hernias (type 1) are the most common (95%) and occur when the GEJ and the proximal stomach move above diaphragm. Sliding hiatal hernias (Fig. 1, top middle) are not considered paraesophageal hernias, and are typically repaired in setting of refractory GERD (addressed in a separate chapter). Type II paraesophageal hernias occur when the gastric fundus moves into the chest alongside a normally positioned GEJ (Fig.1, top right). These are exceedingly rare. Type III paraesophageal hernias are character­ized by the herniation of both GEJ and the fundus and body of the stomach to an intra-thoracic position and account for the majority of the paraesophageal hiatal hernias (Fig.1, bottom left) [8]. Most authors would call a sliding hiatal hernia a Type III paraesophageal hernia when at least 50% of the stomach is herniated into the chest. Finally, Type IV paraesophageal hernias are dened as the herniation of other viscera such as colon, small bowel, or others alongside a Type III paraesopha­geal hernia (Fig.1, bottom right).
Type III Type IV
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GEJ
Normal Type I Type II
Fig. 1 Normal GE junction appearance (top left) and subtypes I-IV of hiatal and paraesophgeal hernias. (Artwork by Clinton T.Morgan, MD)
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3 Preoperative Preparation
An upper GI contrast study is helpful to both establish a diagnosis of a paraesopha­geal hernia and to evaluate gross esophageal motility and length as well as the loca­tion and extent of the supradiaphragmatic stomach. Figure2 shows an upper GI study of a patient with a large type 3 hiatal hernia with organoaxial volvulus. This study can evaluate for volvulus and obstruction and give an assessment of the type of the hernia. Endoscopy should always be performed to measure esophageal length, amount of herniated stomach, amount of volvulus, and mucosal abnormalities including Cameron ulcers, Barrett’s esophagus, or neoplasms [11]. Patients with paraesophageal hernias are often older and may have symptoms warranting cardio­pulmonary evaluation prior to surgery. Esophageal manometry can be helpful to rule out esophageal motility disorders but is also often difcult to obtain in settings of large hernia and volvulus. Pressurization of the stomach against the distal esoph­agus within the chest may also create a falsely elevated integrated relaxation pres­sure and cause a patient to be misdiagnosed with EGJ outow obstruction. Cross sectional imaging in the form of computed tomography can also be helpful to iden­tify anatomy but is not required preoperatively (Fig.3).
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Fig. 2 Barium esophagram showing large type III para-esophageal hiatal hernia with organoaxial volvulus of the intrathoracic stomach
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Fig. 3 Computed tomography of the chest showing a paraesophageal hernia. A large portion of the stomach (green outline), is noted high in the mediastinum, at the level of the heart H note the prox­imity of the posterior aspect of the hernia to the aorta (red outline). On coronal view, the duodenum is seen adjacent to the hiatus (blue outline)
4 Operative Approach
Paraesophageal hernias can be repaired using an abdominal or thoracic approach. They can be repaired via open incision or minimally invasively, with or without robotic assistance. Minimally invasive laparoscopic approach is currently preferred in most centers. The possible benets of the trans-thoracic approach include direct visualization of the sac and hernia, complete mobilization of the esophagus to the aortic arch and the ease of a relaxing incision on the left hemidiaphragm [6, 11]. Disadvantages include the pain of a thoracotomy, higher risk of peri-operative com­plications and the extended length of hospital stay [6, 11]. Most centers in the U.S. favor the use of laparoscopic techniques as complication rates seem lower than
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open approaches and recurrence rates with laparoscopic techniques seem similar to the ones obtained with the trans-thoracic and open abdominal approach [12, 13].
The laparoscopic approach to repair of paraesophageal hernias was rst described in 1992 and emphasized crural approximation and fundoplication [14]. Five steps are essential components of a laparoscopic repair of a paraesophageal hernia:
1. reduction of the hernia contents
2. excision of the hernia sac,
3. complete esophageal mobilization,
4. crural repair, and
5. antireux operation
One of the most important aspects of successful paraesophageal hernia repair is to create a tension-free repair. Axial tension can be addressed with mediastinal esoph­ageal mobilization in most cases. Occasionally, a Collis gastroplasty may be neces­sary. Lateral tension, due to a large diaphragmatic defect, is usually addressed by using appropriate technique for crural closure or an absorbable synthetic or biologic mesh. However, in selected cases relaxing incisions with or without absorbable mesh placement may be benecial [11, 13, 15]. Only absorbable synthetic or bio­logic mesh should be used at the hiatus. Non-absorbable meshes should be avoided as they have potential to erode into the esophagus. However, even the use of absorb­able synthetic or biologic mesh is controversial since its efcacy in long-term objec­tive recurrence has not been demonstrated [13]. Reduction of early recurrences with biologic mesh placement, however, may be one advantage over primary repair [16].
Laparoscopic repair is associated with less blood loss, fewer intraoperative com­plications, faster diet advancement, and shorter hospital stays [6, 17]. Unfortunately, the radiographic recurrence rate is still quite high, ranging from 23% to 50% in selected series [15, 1720]. However most radiographic recurrence are small recur­rences of a small portion of the proximal stomach and the vast majority are asymp­tomatic, thus of little clinical signicance and needing no treatment [18, 20].
Laparoscopic port sites are positioned in a conguration similar to that of a stan­dard Nissen fundoplication. An additional 5mm port in the left lower quadrant may be benecial to assist with retraction and dissection. After inspection of the abdomi­nal contents, the left lobe of the liver is retracted cephalad with a self-retaining lapa­roscopic retractor, exposing the hiatal defect and hernia (Fig.4).
Fig. 4 Laparoscopic view of hiatus with giant hiatal hernia. RC right crus, LC left crus, S stomach, P pylorus
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5 Description oftheLaparoscopic Procedure
5.1 Positioning andAnesthesia
All patients should undergo induction of general anesthesia with endotracheal intu­bation using techniques to prevent aspiration. The patient should be placed in either the supine position or on a split-leg table. The arms are secured on padded arm boards at a 90° angle to the body’s axis. A footboard is placed and the patient secured to the bed in anticipation of a steep reverse Trendelenburg position during the case. An orogastric or nasogastric tube can be placed as needed to decompress the stomach. Sequential compression devices should be placed on the lower legs bilaterally and subcutaneous heparin can be administered for deep vein thrombosis prophylaxis. A foley catheter can be considered for close monitoring of urine output if the procedure is emergent or the patient has multiple comorbidities. The skin of the abdomen should be widely prepped after hair has been clipped short using an atraumatic electric clipper. A single dose of antibiotics should be administered within 1h of incision [21].
5.2 Access andTrocar Placement
Local anesthetic can be used prior to making incisions. Insufation via Veres needle at the left subcostal midaxillary point, followed by placement of a dilating trocar, can be used to obtain access. A laparoscope is inserted and the abdomen surveyed. The remaining trocars can be placed under direct visualization. In total four ports are placed: one 10/12mm port for introduction of sutures and mesh as needed and three 5mm ports. A liver retractor can be used to elevate the left lobe of the liver to expose the hiatus. Alternative liver retraction techniques include use of a suture hammock between anterior hiatus and the falciform ligament to suspend the left lobe [22].
6 Reduction ofHernia Contents andEsophageal
Hiatus Dissection
We typically avoid reducing the stomach by direct traction. The herniated stomach can be easily injured due to underlying edema from acute/chronic incarceration or inammation. If the hiatus is completely obscured by omentum, this can be grasped and reduced to visualize the anterior hiatus. Dissection begins at the hiatal apex, where the hernia sac can be easily grasped and the mediastinum entered right at the junction of hernia sac and diaphragm muscle edge (Fig.5). This allows entry into the mediastinal space. Time and care to identify the precise plane between hernia
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Fig. 5 Anterior starting position of PEH repair, dividing sac and peritoneum of diaphragm
Fig. 6 View of dissection along left crus (LC), with hernia sac (HS) retracted toward screen left.
S stomach, SG short gastric vessels
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sac and mediastinum will pay off here. This avascular plane can be dissected cir­cumferentially along the crura. Consistent retraction of the hernia sac toward the patients feet as dissection progresses will allow preservation of the peritoneum of the crura, and keep your dissection plane inverted into the abdomen for easy visual­ization. It will also prevent encroaching up on the crural muscle itself during repair, which allows for a more robust repair that includes intact peritoneum overlying the crura. This plane is avascular and thus bleeding is typically minimal. Bleeding dur­ing this dissection would indicate that either you are too deep within the mediasti­num or encroaching on the esophageal wall. In either case, care should be taken to reidentify the proper plane before progressing. In general, the left crural pillar is typically easier to dissect than the right (Fig.6). The right pillar has adjacent vascu­lature of the stomach (left gastric artery) which must be avoided during dissection to avoid compromising the gastric blood supply.
Often once a portion of the phrenoesophageal ligament has been divided, insuf­ation will enter the mediastinum and allow passive reduction of herniated contents to fall into the abdomen without any need to place traction upon the stomach. Once it is clear that this has allowed the left gastric pedicle to come intraabdominally, the right crural pillar and pars accida can be divided and the right crural pillar can be followed down to the decussation of the left and right crura (Fig.7). Within the gastrohepatic ligament, there is sometimes a replaced left hepatic artery arising from the left gastric artery. This can be divided after assuring that it is not the sole
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Fig. 7 View of dissection along right crus (RC) and to the posterior crural decussation. LC left crus, IVC inferior vena cava
A. L. Shada
blood supply to the left lobe, but in the case of large PEH can sometimes be left intact.
The hernia sac, which is the thinned out phrenoesophageal ligament, inserts onto the distal esophagus about 2cm above the GE junction (Fig.7). Thus, reduction of the hernia sac into the abdomen usually brings the stomach and GEJ into the abdo­men satisfactorily. One of the tenets of this operation is reduction of at least 2.5cm of esophagus into the abdomen. This can be accomplished with a high mediastinal dissection. Blunt dissection and judicious electrosurgical dissection are reasonable options here. Often the anterior esophagus has only avascular attachments to the anterior mediastinum, and posteriorly the mesentery of the esophagus contains esophageal perforating vessels from the aorta. The inferior pulmonary vein can be identied during a full mediastinal dissection, and often the carina can be visualized as well. The anterior and posterior vagus should be identied early and left intact during dissection. The aorta and inferior vena cava should be identied early and avoided during dissection of the mediastinum. The left and right pleura can also be seen during mediastinal dissection.
Mobilization of the short gastrics is necessary, particularly if a fundoplication will be performed as part of this procedure. This can begin at the watershed area just above the last arcade of the gastroepiploic artery, which his often at the level of the lower pole of the spleen (as measured with the stomach reduced into the abdomen after reduction as above). I would caution an operative approach that starts the dis­section of the hiatus with division of the short gastrics, as they are often very elon­gated and when the entire stomach is intrathoracic there is a risk of devascularizing the entire greater curve of the stomach and perhaps putting the patient at higher risk of postop intragastric volvulus [23].
Complete division of the hernia sac from the crural pillars is an essential compo­nent of this operation. This can be accomplished by alternating between the left and right sides of the mediastinum until the crural edges are free of the sac circumferen­tially. Putting a Penrose drain or similar structure around the esophagus can facili­tate this dissection by allowing retraction. Once the stomach is reduced and the hernia sac has been circumferentially dissected free from the crura, a portion of the
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Fig. 8 The hernia sac (HS) inserts on the distal esophagus about 2cm above the GE junction (Green arrow). HS hernia sac, S stomach
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hernia sac can be removed from the esophagus. This should be routinely performed and helps identify GE junction and also exposes the angle of His for construction of a proper antireux operation. Identication of the vagus nerves prior to removal of the hernia sac can avoid injury to these structures. This will necessitate leaving some of the hernia sac on the lesser curvature side of the stomach to avoid encroach­ing on the anterior vagus, left gastric artery, and even the posterior vagus.
Intraoperative endoscopy can be very helpful to identify the esophagogastric junction and ensure there is adequate intraabdominal esophageal length. Intraabdominal esophageal length measurements can vary depending upon where you measure them from (anterior crus versus left midcrural pillar, for example). Adequate intraabdominal length is typically considered 2–3cm from the left crural pillar to the esophagogastric junction.
In a minority of cases, even a high mediastinal dissection will not allow adequate intraabdominal length. In these cases a lengthening gastroplasty can be performed with a stapler (Fig.8) [6, 24, 25].
7 Crural Repair
Once the hernia sac has been excised, we turn our attention to repair of the hiatal defect. The right crus and left crus are approximated with sutures (Fig.9). We typi­cally use nonabsorbable sutures. Plegets can reinforce closure, and are particularly helpful if the peritoneum overlying the crura has been violated during dissection or if the quality of the crural muscle itself is poor. It is our preference to use bioabsorb­able mesh plegets, but felt plegets have also been described. A simple interrupted suture pattern, horizontal suture pattern, or running suture pattern can be used. The number of sutures needed will vary dependent upon defect size. The crural pillars should be closed to the point that they about the esophageal wall when it is allowed to lie tension free within the hiatus (ie: not being retracted with an instrument or
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Fig. 9 Collis gastroplasty of the proximal stomach, with end target of true GE junction (green arrow)
Fig. 10 Posterior hiatal closure. LC left crus, RC right crus, IVC inferior vena cava
A. L. Shada
penrose drain) (Fig.10). Closing the hiatus too tightly can risk postoperative dys­phagia. Leaving more than a 5mm gap between esophageal wall and crural muscle can risk a recurrent hernia.
If there is excess lateral tension upon the crura during closure, maneuvers includ­ing reduction of CO2 insufation, creation of bilateral capnothoraces, or perfor­mance of relaxing incisions can help bring the crura together without tension.
8 Absorbable Synthetic andBiological Mesh Placement
Mesh reinforcement of the crural closure has been used in an attempt to reduce the relatively high recurrence rates observed after paraesophageal hernia repair [16]. Synthetic mesh has the lowest hernia recurrence rate in randomized studies but ero­sion of permanent mesh into the esophagus is a feared complication and thus syn­thetic mesh should not be used to reinforce diaphragmatic closure[26]. Biologic meshes have a better safety prole and have been shown to improve recurrence rates in the short term but not the long term [16, 27]. Biosynthetic mesh has been used with some success and is a bit less expensive than biologic mesh [2830]. Mesh is typically used as an onlay, and afxed with sutures or glue.
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The largest randomized controlled trials comparing the use of absorbable mesh to no mesh with both 6month and 2year results suggest that the objective success rate seems to be improved with mesh over non-mesh repair in the short term [16,
27]. However, appropriate long-term follow-up is lacking and objective recurrence
tends to increase over time [27, 31]. Another randomized controlled trial found no difference at any timepoint between suture repair and absorbable mesh repair[32,
33]. Notably, the complications from non-absorbable mesh usage can be severe,
including esophageal erosion (0.2%) and extensive hiatal brosis (0.5%) [6, 34]. For these reasons, absorbable mesh is advised [16, 31].
Despite the lack of level I evidence that the use of mesh reduces recurrence rates, newer biological and absorbable synthetic products that are less expensive are com­monly used in practice. The location of recurrence can vary depending on the size of the defect, the timing of the recurrence, and the health of the diaphragmatic tis­sue. We place a U-shaped absorbable mesh around the esophagus at the level of the hiatus. The mesh onlay is placed posteriorly, with the esophagus cupped by the U and the approximated posterior hiatus covered. The mesh may be secured in place with brin glue or sutures.
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9 Antireux Operation
A gastric fundoplication around the distal esophagus is recommended after the clo­sure of the hiatal defect to prevent de-novo or recurrent GERD symptoms after surgery. Some patients have a hypotonic LES and will benet from fundoplication to augment LES tone. All patients have complete disruption of their phrenoesopha­geal ligament by virtue of their hernia as well as the extensive dissection required to repair the diaphragm. Some types of fundoplication also assist in securing the gas­tric fundus to the esophagus and diaphragm as a gastropexy to discourage rehernia­tion. The choice of a posterior complete (360° Nissen), posterior partial (270° Toupet), or anterior partial (180° Dor or Watson) fundoplication is based on indi­vidual patient characteristics and surgeon preferences. Some characteristics that surgeons take into account when deciding on antireux operation of choice include patient characteristics, patient symptoms of reux or dysphagia, esophageal func­tion on preoperative testing, size of fundus, and surgeon preference and comfort with a given antireux operation.
We favor a partial fundoplication as most of these patients have reux as a pre­senting symptom, and many have inherent esophageal motility dysfunction related to advanced age or the chronic nature of the partial obstruction caused by the para­esophageal herniation. A completed posterior 270° fundoplication is shown in Fig.11. The technical steps for the creation of the Nissen, Toupet and Dor fundopli­cations can be found in the “Laparoscopic Antireux Surgery” chapter of this book.