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Minimally Invasive Slings 387
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Figure 14.2.20. Transobturator passage of TOT avoiding space of Ret­zius. (Permission granted by Caldera.)
severe as those with the TVT. Similar to the TVT, the TOT was embraced rapidly by the medical community, with little or no long-term data with regard to safety or success. Despite these limitations, the technique appears to be as good as the original TVT, with fewer injuries.
Technique
Preoperative preparation and anesthesia are the same as those for the TVT. The patient is positioned at the end of the table in the dorsal lithotomy position. A weighted speculum is placed on the posterior vaginal wall. A marking pen is used to make a transverse line at theleveloftheurethraontothe vulva. “X” marks are made 2 cm superior to this line on both sides of the midline just at the medial aspect of the obturator foramen. This spot is usually easily palpable, even in obese patients. Anesthetic with epinephrine is injected at these two spots. Using a small-blade scalpel, stab incisions are made at the injection spots.
Figure 14.2.22. Injection of anesthetic with epinephrine. (Permission granted by Gynecare.)
The same anesthetic is injected under the urethra and lateral toward the obturator foramen (aiming at a 45
angle). A #14 blade scalpel is used to make a 3-cm vertical incision under the urethra. The incision is safely made without entering the urethra if the vaginal epithelium blanches white from the injection. This will also decrease significant blood loss (Figure 14.2.22).
Using either the tenotomy or plastic surgical Metzenbaum scissors, flaps are developed toward the obturator foramen on both sides. Oncetheflapisstarted,thespaceshouldaccommodate the diameter of an index finger. Gentle digital dissection to the obturator foramen will make the operation safer because this will limit the distance that the TOT needle will be out of sight or palpation (Figure 14.2.23).
Figure 14.2.21. “Outside in” TOTneedle passage. (Permission granted by Caldera.)
Figure 14.2.23. Palpation of landmarks during TOT procedure. (Per­mission granted by Caldera.)
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The needle glides overthe guide, through the obturator foramen, and then out through the vulvar incisions.
There are two basic designs for the transobturator needles. One has a corkscrew appearance, and the other looks like a hook. One company (Caldera) offers both types of needles as reusable, and they can be used with different types of sling material (per­manent ordelayedabsorbable mesh).Other systems are designed to clamp onto a proprietary coupling device.
READJUSTABLE SLINGS
Figure 14.2.24. Minimally invasive sling needles. (Permission granted by Caldera.)
The TOT needle is introduced into the vulvar incision on either side and gently rotated or pushed into the flap on that side. The needle will traversetheobturatorforamen and then puncture through the pubocervical fascia into the flap under the guidance of the surgeon’s contralateral index finger. There are differently shaped TOT needles made by different companies, but they all accomplish the same goal (Figure 14.2.24).
Once the needle is in the flap, the preferred mesh/sheath sys­tem isfastened onto the needle, which is then backed out, pulling the mesh/sheath with it. The sheath can be clamped onto the drape to keep it out of the way while the same technique is done on the other side, with the other end of the sheath.
Once both sides have been done, the Foley is removed and cystourethroscopyis performed. If there areno injuries, the blad­der is emptied and the sling is adjusted using the same tensioning technique as for the retropubic TVT (Figure 14.2.25).
Variations
The tension-free vaginal tape-obturator (TVT-O) is an “inside­out” TOT that pushes the mesh from inside the vagina and then out through thevulvar incisions. TheTVT-O uses awinged guide that acts like a shoe horn for the TVT-O needle. The guide is pierced into the obturator foramen through the vaginal flaps.
The first Food and Drug Administration (FDA)-approved read­justable sling was developed in Spain and approved for use in the United States in 2004.[39–41] This sling uses minimally inva­sive techniques with the advantage of allowing the surgeon to adjust the tension at the time of placement, and at any time in the future. Because of the permanent presence of the tension­ing device above the fascia, this sling is best reserved for patients with previous incontinence surgery failures.Before the adjustable sling, bulking agentssuchasContigen (C. R. Bard, Inc.) were used to increase coaptation of the urethral walls. If the bulking did not help, the only other option was to redo the entire sling.
The kit consists of a small piece of polypropylene mesh, two tensioning sutures (Prolene), a tensioning device, and a screw­driver set (Figure 14.2.26).
As with a TVT-type MIS, the mesh isplacedunderthebladder neck or mid-urethra through a vaginal incision. The lateral sides of themesharestitchedwiththeProlene tensioningsutures.These sutures are pulled up through the retropubic space as with the SPARC approach. A small suprapubicincision allows the tension­ing device to be fastened to the two proline sutures. Cystoscopy must be performed to confirm urinary tract integrity. The device is tightened with the screwdriver until it rests directly on top of the rectus fascia. The screwdriver is left exposed through the skin incision. After leaving the operating room, the patient’s bladder is filled with water, and in the standing position, the patient per­forms cough and Valsalva maneuvers. The screwdriver is used to make incremental changes in the suture tension. When the patient achieves continence, she is asked to void, and a postvoid residual is obtained. Assuming the patient can empty well and is
Figure 14.2.25. TOT sling tensioning. (Permission granted by AMS.)
Figure 14.2.26. Remeex kit. (Permission granted by Neomedic/Tri­Anim.)
Figure 14.2.27. Tensioning of the Remeex device. (Permission granted
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by Neomedic/Tri-Anim.)
dry, the screwdriver is detached from the tensioning device and the incision is closed (Figures 14.2.27, 14.2.28).
Because of thepresenceofa prosthesis, antibiotic coverage for 7 to 10 days is recommended to avoid infection, although at least one study suggests that routine antibiotic use in an uncompli­cated patient may not beofsignificant value.[42–44] If the patient develops recurrent incontinence, readjustment ofthe sling is pos­sible by opening the incision just enough to allow entry of the screwdriver. The same test protocol is used again. Because there is adequate support under the urethra secondary to the Prolene mesh, leak point pressure can be increased by tightening the lat­eral sutures.
Although long-term data on the adjustable sling are lacking, preliminary studiesindicate cure ratesin the range of 95.5%.[38– 40] For patients with continued leakage, improvement is also significant. Given the unique nature of the readjustable sling, it warrants further investigation.
Minimally Invasive Slings 389
COMPLICATIONS
Among all types of MIS, complications are common. Early stud­ies show that the retropubic approach probably has more over­all injuries than do the transobturator slings. Most retropubic sling injuries are minor and resolve spontaneously. This is prob­ably related more to the anatomic placement of the sling than to the absolute skill of the surgeon. There have been severe injuries reported, some resulting in death. Attentiontodetailisimperative to ensure a positive outcome. Skill alone will help, but complica­tions will never be eliminated.
Bladder Perforations
In retropubicMIS, bladder perforations occur in up to 5% ofcases [17–19], although thefrequencydecreasesprecipitouslywith sur­gical experience. As long as the perforation site is not bleeding, nothing more needs to be done. If bleeding is seen, the bladder may be filled with sterile water for a few minutes. This is usually enough tostop the bleeding bytamponade. When active bleeding is seen, it is best to leave aFoley in place until the urine is clear for at least 24 hours. This is typically enough time for the cystotomy to heal itself. If multiple cystotomies are seen, or if the hole is larger than the diameter of the needle, longer bladder drainage may be indicated.
The TOT slings are inserted lateral to the urethra and are a few centimeters away from the bladder. Although bladder per­forations do occur with TOT slings, the rate of these injuries is significantly lower (2%)than those ofTVTs.[45–47] It has been suggested by some of the companies producing TOT slings that cystoscopy is not indicated. Some surgeons consider this to be a marketing gimmick to sell more slings to physicians who do not have cystoscopy privileges. Although bladder and urethral injuries are uncommon, they do occur. Most experienced sur­geons would consider cystoscopy an essential part of any incon­tinence procedure.
Patients receiving the readjustable sling have had numerous anti-incontinence procedures in thepast. Complication rateswill probably be increased in this population. Cystoscopy with the use of indigo carmine dye to visualize ureteral patency is advised during the case.
Figure 14.2.28. Closure of the skin with Remeex screwdriver in place. (Permission granted by Neomedic/Tri-Anim.)
Vascular Injury
Retropubic slings such as the TVT are associated with a very low incidence of vascular injury. Because the needles are placed blindly, relying on anatomic landmarks, the needles may some­times wander. A small change in the angle of placement can mean the difference between being safely lateral to the bladder and perforating the external iliac or obturator vessels. These ves­sels are only 4 to 6 cm away from where the needle should be passed.[47,48]
If a major blood vessel is injured, the patient typically will show symptoms. She may experience a drop in blood pressure, swelling or ecchymosis in the lower abdomen or vulva. She may also have visible blood pouring out of the vaginal or abdominal incisions. If there is bleeding only at the suburethral incision, the blood most likely is fromthe superficial plexus of veins.Firm pres­sure held in the vagina for 5 or 10 minutes can stop or slow blood loss, allowing the procedure to be completed. Packing can be left in thevagina andremoved in therecovery room afew hours later.
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Bleeding that does not slow down or that starts coming through the abdominal incision is more worrisome. This may indicate a major vessel injury and requires immediate decision making. Ifthe blood is oozing out of theincisions only, firm pres­sure held over the lower abdomen and from the vagina for 5 or 10 minutes should be attempted first. Extra tamponade can be provided by retrograde filling of the bladder with water through the Foley catheter.
If the bleeding does not significantly slow down after 10 min­utes, anabdominal incision may be warranted. Superficial vessels can be ligated or coagulated. Larger vessels may need repair, and a vascular surgery consult may be indicated. Overall transfusion rates are much less than 1% in experienced hands.[18, 50, 57]
Postoperative hematomas are common and usually asymp­tomatic. If the size of the hematoma appears stable and the patient is without complaint, observation only is indicated. If the hematoma appears to be enlarging or if the patient is becom­ing symptomatic, sonographic imaging is helpful to determine its size. In some cases, the hematoma can be drained undersono­graphic guidance. Infected hematomas are rare, but antibiotic augmentation may be considered.
Bowel Injury
Bowel injuries are always considered life threatening and require immediate intervention once they are recognized. Unfortunately, most bowel injuries go unnoticed until the patient has signs of an acute abdomen or sepsis. It seems difficult to picture how the bowel could be perforated with an MIS needle until one does cadaveric dissections and sees how close the intraperi­toneal contents are to the retropubic space. Bowel injuries have been reported in the literature during suprapubic catheter placement.[52–54] Patients who have had previoussurgery inthe retropubic space are at an increased risk of injury, as the bowel may have slid into the space. This is why the peritoneum must be closed during any concurrent abdominal procedure (open or laparoscopic) to prevent herniation of the small bowel into the space anterior to the bladder.
Patients undergoing the readjustable sling need to be treated a little differently. Many candidates for this procedure have had multiple prior surgeries. Patients with a history of prior abdomi­nal approach pelvic surgery are at increased risk of bowel injury. Overnight observation may be warranted. Any clinical signs of peritonitis require an extensive and immediate work-up.
Patients with a bowel injury may present with an acute abdomen, nausea, vomiting, and diarrhea. Fever and elevated white blood count are frequently seen. These patients look sick. When a patient complains of any lower abdominal pain postop­eratively, she must be taken seriously.
Evaluation for bowel injury may include a flat plate and upright radiograph to look for free air, bowel obstruction, or ileus. A computed tomography (CT) scan can show changescon­sistent with bowel injury, including free air. A sonogram may also be helpful. Bowel injuries require aggressive management with resection, drainage, and possible colostomy if indicated.
Wound Infections
Surgical site infections are very rare secondary to prophylactic antibiotics. It is has been suggested that the outer sheath reduces
the bacteria load after they are removed. Some surgeons soak the MIS inan antibiotic solution before starting the case.One animal study using a polymer mesh soaked for 15 minutes in rifampicin, vancomycin, and gentamicin showed decreased infection rates when the mesh was reimplanted into rabbit tissue.[33,55–57]
POSTOPERATIVE MANAGEMENT
Incomplete Bladder Emptying
If the patient has failed thevoiding trial, eitheran indwellingFoley catheter is left in place or the patient begins intermittent self­catheterization. Most commonly, the patient is sent home with the catheter,a leg bag, and a night bag. The Foley will stay in place for 2 to4 days, after which anothervoidingtrial will be attempted. Repeated failure of the voiding trial results in approximately 3% to 5% of patients with less than 1% needing a sling revision.[58– 60] Earlyintervention in the first 2weeks will allow the slingto be loosened by opening up the vaginal incision and gently pulling down on thelateralsidesof the exposed sling.This allows the sling to remain flat under the urethra, without disrupting its integrity. After 2 weeks, the sling will have started to have tissue ingrowth, and it is best to wait for 4 to 6 weeks after surgery to cut the sling in the midline. In cases in which the patient has no urine output, resection ofthemid-portion of thesling may be indicated if the sling cannot be loosened. Continued continence with good bladder emptying occurs in over 85% of patients undergoing revision. Patients with borderlinehigh residuals will oftenrequire occasional self-catheterization. In this smallsubgroupofpatients, many will prefer to continue self-catheterizing rather than risk becoming incontinent again.
As a rule, tight slings can be loosened by cutting them under the urethra. Loose slings need to be redone or improved with bulking agents. Experienced surgeons will often make the sling “tighter” rather than “looser.”
Antibiotic therapy with nitrofurantoin 50 mg/day is helpful in preventing urinary tract infections in patients with an indwelling catheter. Antibiotics are not indicated in patients who use the intermittent self-catheterization technique.
Vaginal and Urethral Erosions
It is difficult to determine whether a sling has eroded into the vagina or was inadvertently placed there at the time of surgery. This difficulty applies to slings found in the urethra as well. The time from surgery thattheerosionisfound probably gives the best indication of the cause.Ifthesling is found withinthefirst month, it is probably the result of surgical error. This is not always the case, however, as suture lines can break down and some patients have decreased tissuevascularity secondary to prior medical con­ditions.
Mesh in the vagina often presents with persistent vaginal dis­charge or odor, or the patient’s partner may complain of pain during sexual relations, which may be accompanied by the find­ing of small lacerations on the partner’s penis (which does not require examination). Thisproblem is bestdealt with in the oper­ating room, with the patient under anesthesia. The visible mesh should either be resected or be completely covered over with healthy vaginal epithelium. In most cases, resection will be the easiest approach, and the entry and exit sites should be closed
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with absorbable suture. Cases in which only a small amount of mesh is palpable but not seen, may respond to 8 to 12 weeks of topical estrogen cream.
Urethral erosions require removal of the material. This can be attempted transurethrally but usually requires a vaginal approach. Developing a few layers of inverted u-flaps under the urethra helps to identify the sling and also preserves the urethral sphincter.By taking down the tissue inthin layers, minimal dam­age is done to the urethra itself, allowing a repair that decreases the risk of urethra–vaginal fistula. If the erosion into the urethra requires extensive repair,it is best to leave a transurethral catheter in place for 5 days to prevent stricture of the healing urethra. In these cases, a suprapubic catheter is also placed for up to 10 days to divert urine flow and allow adequate healing.
Pain
Pain control is rarely a problem. A few days of nonsteroidal anti­inflammatory drug (NSAID) therapy is usually enough. Patients who demand or require stronger medication warrant immedi­ate evaluation because of the unusual nature of the complaint. Continued pain may be caused by a range of conditions, with most being self-limited. A urinary tract infection should always be looked for first. A digital exam of the vagina will rapidly rule out the presence of mesh in the vagina. Rarely, patients are sent home without removal of the vaginal packing. Retained packing presents as “pressure” that quickly resolves once it is taken out.
Complaints of protracted pain may occur along the path of the sling placement. This is not dependent on improper tech­nique, as the patient may be completely continent, with good bladder emptying. There is no “one cause” for this occurrence, but most symptoms abate after 4 to 8 weeks of NSAIDs. If pain is present after 12 weeks, excision or release of the sling is advised. It is not easy to excise the sling in its entirety because of tissue ingrowth.[61–65] It is usuallypossibletoremovemostofthe sling to the obturator foramen bilaterally or near the pubocervical fas­cia.
Failures
mayrequireyearlyrepeatinjections.These injections can be easily applied and performed in the office if necessary.
New in-office modalities using radiofrequency therapy are now FDA approved but still lack long-term data. Clinical trials are under way and show improvement in up to 80% of patients treated. It is unclear how this therapy will affect the urethra in cases in which a sling will be placed at a later time. If this therapy demonstrates encouraging results, it may be considered a first­line treatment in patients who either do not want surgery or are poor surgical risks.
Patients who develop hypermobility of the anterior vaginal wall after a sling has been placed are at increased risk not only of recurrent stress incontinence but also of urinary retention.[66– 69] Retention occurs when the sling, acting as a fulcrum, causes kinking of the urethra and bladder neck as the anterior vagi­nal wall descends. These patients will have stress incontinence secondary to overflow from incomplete bladder empting. Re­support ofvaginal mobility willusually correct the problem with­out having to redothe sling. Placing a pessary into thevagina will sometimes cure the problem by relieving the kink. Although not always an accurate predictor of success, the pessary can give a good indication of how corrective surgery will work.
SLINGS WITH CONCOMITANT SURGERY
The sling should bethelastprocedureperformedwhen combined with other surgery. This is because it is important to have the anterior vaginal wall and urethra resting at the point where the sling is placed. If the vaginal wall and urethra are moved in any direction (i.e., posterior repair or apical suspension), this may increase or decrease the tension placed on the sling. This can increase the risk of retention or continued incontinence.
For surgeons who are doing laparoscopy, the Burch or MMK procedure may be their primary incontinence procedure. By avoidingthe retropubic space, decreased morbidity andincreased success rates may be achieved by switching to a MIS. Overall, the MIS is applicable to a wider range of patientsthan is any retropu­bic bladder neck suspension. It may also decrease operative time.
Patients with continued incontinence require reassessment. In most cases, the anterior vaginal wall is still well supported but the sling is justtoo loose. Retesting with urodynamicsis the best place to start. Confirmation that the patient has stress incontinence and not de novo urge incontinence is helpful from a practical and legal perspective. Some patients may think they have stress incontinence, but the leakage is really caused by a contraction of the detrusor muscle of the bladder. Reoperating on patients without true stress incontinence will only make their symptoms worse. These patients will respond to anticholinergic medical therapy. Patients who continue to have stress incontinence have a few treatment options.
When the incontinence is severe, repeating the initial MIS is probably the best place to start. Patients who have already had more than one anti-incontinence procedure will probablybenefit from the readjustable sling. For patients whohave improved with the MIS, urethral bulking shouldbeconsidered.Differentbulking agents are available, and improvement in the condition can be expected,butthismayrequiremorethanonesessionofinjections. Long-term cure has not been seen with these products, and they
CONCLUSION
The MISis now considered the“goldstandard” for stress inconti­nence therapy. Long-term safety data confirm low morbidity and mortality rates.[70–73] Cases can be done in the ambulatory set­ting and do not require extensive recovery periods. Familiarity of pelvic anatomy and a thorough understanding of the pathophys­iology of bladder dysfunction are essential. This will ensure the proper choice of both the procedure and the technique. Despite any marketing ploy to the contrary, cystourethroscopy should still be considered essential during these procedures.
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44. Garcia Florez D, Perez Sanz P, Briones Mardones G, et al. Surgical management and complications of urinary stress incontinence: our experience in 385 patients operated on during thelast 25years [in Spanish]. Actas Urol Esp. 2003;27:92–96.
45. Roumeguere T, QuackelsT, Bollens R, et al. Trans-obturator vagi­nal tape (TOT) for female stress incontinence: one year follow-up in 120 patients. Eur Urol . 2005;48:805–809.
46. Smith PP, Appell RA. Transobturator tape, bladder perforation, and paravaginal defect: a case report. Int Urogynecol J Pelvic Floor Dysfunct . 2007;18:99–101.
47. Mellier G, Benayed B, Bretones S, Pasquier JC. Suburethral tape via the obturator route: is the TOT a simplification of the TVT? Int Urogynecol J Pelvic Floor Dysfunct. 2004;15:227–232.
48. Abbas ShobeiriS,Gasser RF, Chesson RR, Echols KT. Theanatomy of midurethral slings and dynamics of neurovascular injury. Int Urogynecol J Pelvic Floor Dysfunct. 2003;14:185–190.
49. Agostini A, Bretelle F, Franchi F, Roger V, Cravello L, Blanc B. Immediate complications of tension-free vaginal tape (TVT): results of a French survey. Eur J Obstet Gynecol Reprod Biol. 2006; 124:237–239.
50. Bourrat M, Armand C, Seffert P, Tostain J. Complications and medium-term functional results of TVT in stress urinary inconti­nence [in French]. Prog Urol. 2003;13:1358–1364.
51. Kobashi KC, Govier FE. Perioperative complications: the first 140 polypropylene pubovaginal slings. JUrol. 2003;170:1918–1921.
52. Noller KL,Pratt JH, Symmonds RE.Bowelperforation with supra­pubic cystostomy: report of two cases. Obstet Gynecol. 1976; 48(suppl 1):67S–69S.
53. Farina LA, Palou J. Re: suprapubic catheterisation and bowel injury. BrJUrol. 1993;72:394.
54. Parikh A, Chapple CR, Hampson SJ. Suprapubic catheterisation and bowel injury. BrJUrol. 1992;70:212–213.
55. Goeau-Brissonniere O,LeflonV, LetortM,NicolasMH. Resistance of antibiotic-bonded gelatin-coated polymer meshes to Staphylo- coccus aureusin arabbit subcutaneous pouch model. Biomaterials. 1999;20:229–232.
56. Debodinance P, Delporte P, Engrand JB, Boulogne M. Complica­tions ofurinary incontinencesurgery: 800 procedures [in French]. J Gynecol Obstet Biol Reprod (Paris). 2002;31:649–662.
57. Kochakarn W. Tension-free vaginal tape procedure for the treat­ment of stress urinary incontinence: the first experience in Thai­land. J Med Assoc Thai. 2002;85:87–91.
58. Meschia M, Pifarotti P, Bernasconi F, et al. Tension-free vaginal tape: analysisof outcomes andcomplications in 404stress inconti-
nent women. Int Urogynecol J Pelvic FloorDysfunct. 2001;12(suppl
2):24–27.
59. Marteinsson VT. Reoperations on lower urinary tract due to for­eign bodyafterurinary incontinence surgery [inIcelandic].Laekn- abladid. 2005;91:237–241.
60. Kato K, Hirata T, Suzuki K, Yoshida K, Murase T. Sling removal after the Vesica sling and tension-free vaginal tape (TVT) proce­dures [in Japanese]. Nippon Hinyokika Gakkai Zasshi. 2004;95:17–
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61. Hermieu JF,MilcentS.Syntheticsuburethralsling in the treatment of stress urinary incontinence in women [in French]. Prog Urol. 2003;13:636–647.
62. Gonzalez R, Fugate K, McClusky D 3rd, etal.Relationshipbetween tissue ingrowthandmeshcontraction.Wo r ld J Su rg .2005;29:1038–
1043.
63. Matthews BD, Pratt BL, Pollinger HS, et al. Assessment of adhe­sion formation to intra-abdominal polypropylene mesh and poly­tetrafluoroethylene mesh. JSurgRes. 2003;114:126–132.
64. Slack M, Sandhu JS, Staskin DR, Grant RC. In vivo comparison of suburethral sling materials. Int Urogynecol J Pelvic Floor Dysfunct. 2006;17:106–110.
65. Junge K,KlingeU,RoschR,KlosterhalfenB,SchumpelickV.Func­tional andmorphologic properties of amodifiedmesh for inguinal hernia repair. WorldJSurg. 2002;26:1472–1480.
66. Hammad FT, Kennedy-Smith A, Robinson RG. Erosions and urinary retention following polypropylene synthetic sling: Aus­tralasian survey. Eur Urol. 2005;47:641–646.
67. Thiel DD, Pettit PD, McClellan WT, Petrou SP. Long-term uri­nary continence rates after simple sling incision for relief of uri­nary retention following fascia lata pubovaginal slings. JUrol. 2005;174:1878–1881.
68. Sweeney DD, Leng WW. Treatment of postoperative void­ing dysfunction following incontinence surgery. Curr Urol Rep. 2005;6:365–370.
69. Palma PC, Dambros M, Riccetto CL, Thiel M, Netto NR Jr. Transvaginal urethrolysis for urethral obstruction after anti­incontinence surgery [in Spanish]. Actas Urol Esp. 2005;29:207–
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70. Rackley RR,Abdelmalak JB,TchetgenMB,Madjar S,Jones S,Noble M. Tension-free vaginal tape and percutaneous vaginal tape sling procedures. Tec h U ro l . 2001;7:90–100.
71. Rutman M, Itano N, Deng D, Raz S, Rodriguez LV. Long-term durability of the distal urethral polypropylene sling procedure for stress urinary incontinence: minimum 5-year followup of surgical outcome and satisfaction determined by patient reported ques­tionnaires. JUrol. 2006;175:610–613.
72. Flynn BJ, Yap WT. Pubovaginal sling using allograft fascia lata versus autograft fascia for all types of stress urinary incontinence: 2-year minimum followup. JUrol. 2002;167(2 pt 1):608–612.
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Section 14.3. Laparoscopic Uterine Suspension, Sacrocolpopexy,
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Vault Suspension
James E. Carter and Senzan Hsu
PART 1: LAPAROSCOPIC UTERINE
SUSPENSION
LAPAROSCOPIC UTERINE SUSPENSION FOR PAIN AND UTERINE RETROVERSION
Uterineretroversionisabackwarddisplacementofthe uterus into the pouch of Douglas from its normal anteverted position.[1] Uterine retroversion may be congenital or may result from adhe­sions and fibrosis. The condition occurs in20%to30%ofwomen. Commonly reported symptoms include dysmenorrhea, dyspare­unia, and backache. Laparoscopic ventral suspension has been performed to successfullytreatsymptomatic retroversionandsig­nificantly reduce symptoms.[1–17] Long-term follow-up of 5 to 20 yearshas demonstrated continued relief of chronic pelvic pain and deep dyspareunia by uterine suspension.[14] Several tech­niques have been described to treat uterine retroversion. These include suspension of round ligament at midpoint, modified Olshausen uterine suspension, and the Uterine Positioning by Ligament Investment, Fixation, and Truncation (UPLIFT) tech­nique.
Ventral Suspension of the Round Ligaments at the Midpoint
This procedure involves the placement of two 5-mm suprapu­bic trocars and the introduction of grasping forceps into the pelvis throughthem. Alternatively, longKellyclamps are inserted through suprapubic stab incisions. Both round ligaments are grasped near their midpoints, and partial escape of pneumoperi­toneum is allowed. The knuckle of the round ligament is pulled gently and firmly through the fascial incision (Figure 14.3.1.1). The round ligaments are sutured to the rectus fascia with 2-0Ethi­bond nonabsorbable sutures (Ethicon, Somerville, NJ). Uterine position is confirmed with the laparoscope, and one must avoid kinking the fallopian tubes.[18,19]
Potential complications with this procedure include avulsion of the round ligaments secondary to inadequate fascial incision and undue tension or positioning of the round ligaments with full pneumoperitoneum. The inferior epigastric arteries may be lacerated during placement of the suprapubic trocars. Although transilluminating the abdomen often helps prevent this compli­cation, it is difficult in obese patients. For most patients, inci­sional pain and discomfort are managed with mild analgesics and a heating pad. Occasionally, patients who experience more significant postoperativepain from secondary spasms of the recti
muscles are relieved with heat, muscle relaxants, and analgesics. Patients are advised to avoid strenuous exercise for 4 to 6 weeks postoperatively.
Modified Olshausen Uterine Suspension
A delayed absorbableor permanent sutureis passed transabdom­inally at the suprapubic trocar site, using a swaged-on needle. While the round ligament is placed on stretch, several areas are taken where the round ligament enters the inguinal canal mov­ing toward the uterus. Approximately 2 cm from the uterus, the direction of the needle is reversed and a similar maneuver is per­formed along the length of the round ligament to the inguinal canal. The needle is passed transabdominally. After both sides have been completed, pneumoperitoneum is decreased, and the suture is tied above the fascia (Figure 14.3.1.2). The result is a plication of the round ligaments.
The UPLIFT Procedure
The UPLIFT laparoscopic uterine suspension is performed with a Carter-Thomason 2-mm needlepoint suture passer. A tiny skin incision is made near the exit point of the round ligament into the inguinal canal (Figure 14.3.1.3). Size 0 (3.5 metric) monofil­ament polybutester suture is used to make two passes subcu­taneously and transfascially into the extraperitoneal space and within and along the round ligament (Figure 14.3.1.4A–F). The first pass’s exit point of the suture is 0.5 to 1.0 cm from the uterus in the fibrous portion of the ligament. The second pass starts 1 to 2 cm cephalad or caudad from the previous puncture site. The exit point of the suture from the ligament is approximately 1 to 2 cm proximal to the exit point of the previously placed suture. The suture is retrieved and withdrawn to outside of the skin and tied. This technique creates a pledget of round ligament and a bridge of fascial tissue. The ligament imbricates within itself as it is pulled up by the suture. This moderately anteverts the uterine position by ligamentinvestment, fixation, andtruncation (Figure
14.3.1.5). Useofthis techniquehas resulted in an average operating time
of less than 15 minutes for this portion of the patient’s surgery. In one series of 75 patients [20], the average time to discharge was 4 hours. Mild incisional and abdominal wall discomfort, which occurred in most patients for the first 24 hours, was read­ily relieved with mild oral analgesics. There were no intraopera­tive complications. After theUPLIFT and associated laparoscopic procedures,immediateandsustainedreliefof pelvicpainhasbeen reported in majority of patients.[20,21]
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Laparoscopic Uterine Suspension, Sacrocolpopexy, Vault Suspension 395
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Figure 14.3.1.1. The round ligaments at midpoint are pulled through the suprapubic incision and tied to the rectus fascia.
Multiple procedures for uterine suspension have been described in the literature that involve folding, plicating, bend­ing, and fixingtheround ligament to theanteriorabdominal wall, and these procedures have been reported as being successful. The UPLIFT procedure avoids potential problems with bowel herni­ation into the anterior cul-de-sac, which may occur with some of the other procedures. It also results in an anatomically correct anteversion, with the suspension at the lateral extension of the round ligaments.
LAPAROSCOPIC UTERINE SUSPENSION FOR DESCENSUS
Maher and colleagues [22] described laparoscopic suture hys­teropexy for uterine prolapse in women wishing uterine preser­vation. As Maherpointedout, “Vaginal hysterectomy remains the acceptedsurgicaltreatment for womenwith uterine prolapse. The Manchester repair is favored in women wishing uterine preser­vation. Vaginal hysterectomy alone fails to address the patholog­ical cause of the uterine prolapse. The Manchester repair has a
Extracorporeal knotApplying sutures
Figure 14.3.1.2. Modified Olshausen technique.
Anterior
superior
iliac spine
Ilioinquinal
nerve
Figure 14.3.1.3. Position ofthe skinnicksrelativeto theexitingpointof the round ligament through the inguinal canal. The retroverted uterus is pictured before uterine suspension. (Courtesy of Inlet Medical, Inc.)
Skin
nick
Genitofemoral
nerve
Iliac
artery
Iliohypogastric
nerve
high failure rate and may causedifficulty sampling the cervix and uterus in the future. The laparoscopic suture hysteropexy offers physiologic repair of uterine prolapse.”
Maher performed surgery as follows: Surgery was performed in a low lithotomy position. The bladder was drained with a Foley catheter, and a Pelosi uterine manipulator (Apple Medical, Bolton, MN) was used to obtain exaggerated anteversion of the uterus. A steep Trendelenburg position facilitated mobilization of the bowel from the pouch of Douglas. Following placement of two 5-mm ports for performance of the surgery, the bowel was removedfrom the pouch ofDouglas, and thecourseof the ureters was followed from the pelvic rim along the lateral sidewall.As the cul-de-sac at this stage is an expansive hernia-like area between the bowel posteriorly and the cervix and posterior vaginal wall anteriorly, the uterosacral ligaments are frequently deficient. A Moschcowitz culdoplasty was performed using a size 0 polydiox­anone purse-string suture. The uterosacral ligaments were inde­pendently plicated using two size 1 Gore-Tex sutures (CV-2, Gore, Flagstaff, AZ).The uterosacral ligamentplication started midway along the uterosacral ligament between the sacrum and thecervix. The ligamentswere reattached to theirpoint ofphysiologic inser­tion on the posterior aspect of the cervix. At the completion of surgery, a 3- to 4-cm gap was left between the sacrum and the plicated uterosacral ligamentstoensure normal largebowelfunc­tion. The course of the ureterswas checked.Ifkinkingwaspresent, a peritoneal releasing incision was performed between the ureter and uterosacral ligaments
In the 43 women who underwent this procedure for symp­tomatic uterine prolapse to or beyond the introitus with straining, Maher reported that the mean operating time for the laparo­scopic suture hysteropexy was 42 ± 15 minutes and the mean blood loss was 50 mL or less. Intraoperatively, one woman had broad ligament hematoma resulting from laceration of the left uterine artery. Peritoneal releasing incisions were performed in two women in whom the ureter was kinked medially, close to the plicated uterosacral ligament. No postoperative complications were reported. With a mean length of follow-up of 12 months (range 5–19 months), majority of women had no symptoms of or no objective evidence of prolapse (81% and 79%, respec­tively). Seven women (16%) underwent additional surgeries for symptomatic uterine prolapse such as abdominal and sacral colpopexy, vaginal hysterectomy, and sacrospinous vault suspen­sion and sacrospinous hysteropexy. Two women subsequently
396 James E. Carter and Senzan Hsu
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Skin
TM
suture
TM
MetraGrasp
ligament
grasper
Round ligament
TM
MetraPass
suture passer
Fat
Fascia
Peritoneum
A
MetraPass
passer inserted within
the round ligament
B
Creating the Fascial Bridge
C
Figure 14.3.1.4. The UPLIFT procedure creates thickened, shortened, and strengthened round ligaments. (A) The polybutester suture is grasped and passed subcutaneously. (B) The suture exits the round ligament 0.5 to
1.0 cm from the uterus in the fibrous portion of the ligament. (C) The empty suture passer is passed 1 to 2 cm cephalad to caudad from the first pass. (continued )
completed term pregnancies, delivered by cesarean section, and were without prolapse at follow-up.
Yen et al.[23], believing that uterine retrodisplacement itself was associated with dyspareunia, chronic pelvic pain and uterine prolapseintheabsenceoforganicdisease,describedtheefficacyof amodifiedtechniquetotreata symptomaticretrodisplaced uterus with a combination of laparoscopic shortening and plication of the uterosacral ligaments and modified Gilliam round ligament suspension.
The surgery began by noting the anatomic relationship of rectum, ureters, and uterosacral ligaments to avoid injury. Four size 0 propylene sutures were placed (two on the left uterosacral ligament and two on the right) to make a circle. Beginning with the left uterosacral ligament, the first suture was placed at the lower level near the pelvic wall beside the junction with the rec­tal margin. A deep bite of the ligament was included while care was taken to avoid the rectum and ureter. The second suture was placed at the upper part of the left uterosacral ligament at the