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252 Atlas of Gastrointestinal Surgery: Pancreas
and medial to it, is exposed. This allows dissection of the uncinate process away from the superior mesenteric artery (1). This is done with the operator’s left hand placed posteriorly, behind the extensively kocherized duodenum and head of the pancreas. Once the uncinate process has been completely dissected away from the superior mesenteric artery, all of the pancreatic tissue (except for that portion that resides in the duodenal C loop) has been mobilized. The tail, body and neck of the pancreas have been dissected out of the retroperitoneum. The unci­nate process has been mobilized from underneath the supe-
Body of pancreas
Portal v.
Superior mesenteric v.
Splenic v.
1
rior mesenteric and portal veins and away from the lateral bor­der of the superior mesenteric artery.
Prior to dividing the pancreas in the duodenal C loop, it is essen-
tial that either a Bakes dilator or a biliary Fogarty balloon catheter is placed in the common duct down through the ampulla into the duodenum. If a cholecystectomy has not previously been performed, it is performed, and a biliary Fogarty balloon catheter is passed through the cystic duct into the ampulla. This allows one to
Gall bladder fossa
identify the location of the common duct as it courses through the posterior aspect of the pancreas, medially to the second por­tion of the duodenum, before coursing laterally to enter the duodenum via the
Head of pancreas
Cystic duct
Uncinate process
ampulla. If the gall bladder has been removed, the common duct should be opened and a Bakes dilator passed through the ampulla into the duode­num. Once the course of the common duct has been identified, using the electrocautery, the pancreas is divid­ed as close as possible to the duode­nal C loop, while carefully staying away from the common duct (2).
2
Kocherized duodenum
Balloon catheter
Ninety-Five Percent Distal Pancreatectomy for Chronic Pancreatitis 253
The inferior and superior pancreaticoduodenal vessels course in the groove at the junction of the pancreas and the medi-
al aspect of the duodenal C loop. There is little danger of injuring these vessels, since one needs to stay several millime­ters away from the C loop to avoid injuring the common duct. There is both a posterior and an anterior pancreaticoduo­denal arcade, and as long as one of these arcades is left intact, there is no concern about duodenal viability.
Once the pancreatic tissue has been completely divided, one is left with a strip of pancreatic tissue in the duodenal
C loop. The pancreatic duct is identified and sutured with a mattress suture of 3-0 silk (3). The remnant at this point is small, unless the head of the pancreas is markedly enlarged; in the latter case, a relatively broad remnant of pancreas is left behind. It is in these patients that further symptoms are occasionally seen. In most instances, however, most of the pancre­atic tissue can be shaved away from the duodenal C loop without risk of injury to the common duct or vascular supply to the duodenum. The remnant is drained with two closed suction Silastic drains brought out through stab wounds in the left upper quadrant.
Gall bladder fossa
Liver
Cystic duct stump
Portal v.
Splenic v.
Stomach
Retroperitoneal bed
Transverse colon
Superior and inferior pancreaticoduodenal vessels
Pancreatic remnant
Pancreatic duct
Inferior mesenteric v.
3
Superior mesenteric v.
Local Pancreatic Head Resection with Lateral Pancreaticojejunostomy (The Frey Procedure)
Operative Indications:
The indications for the Frey procedure for chronic pancreatitis are virtually identical to the indications for the Puestow pro­cedure: chronic pancreatitis, abdominal pain, and a dilated pancreatic duct. For the Puestow procedure, it is felt that a pancreatic duct diameter of 5 to 6 mm in diameter or greater is required. The Frey procedure has been extended to patients with duct dilatation as little as 3 mm, because resection of tissue in the head of the pancreas is combined with decom­pression of the pancreatic duct. In addition to patients with persistent pain from chronic pancreatitis, the Frey procedure has also been used in patients with recurrent episodes of acute pancreatitis and a dilated pancreatic duct. Finally, patients with a stricture in their distal biliary tree from chronic pancreatitis can benefit from the Frey procedure, which resects tissue in the head of the pancreas that can result in decompression of the biliary tree.
Operative Technique:
The initial steps in the Frey procedure are similar to those in the Puestow procedure. The abdomen is entered either through a bilateral subcostal or an upper midline inci­sion. The abdomen is first explored for other pathology. The omentum is taken off the transverse colon and reflected cephalad. This allows one to examine the entire neck, body and tail of the pancreas, and often the dilated pancreatic duct can be palpated. In addition, the head of the pancreas should be mobilized with an extensive kocheriza­tion, so the head and uncinate process can be palpated.
Local Pancreatic Head Resection with Lateral Pancreaticojejunostomy (The Frey Procedure) 255
The neck of the pancreas is dissected along its inferior border, and the superior mesenteric vein is identified. The por-
tal vein is then identified along the superior border of the neck of the pancreas. It is helpful to loop the neck of the pan­creas with a small Penrose drain so that, during the resection of the head of the pancreas, these venous structures and the superior mesenteric artery location are clearly identified. The dilated pancreatic duct is then identified by aspirating with a 20-gauge needle and a 10-ml syringe. If difficulty in identifying the dilated pancreatic duct is encountered, intraoperative ultrasound may be of help. Once the dilated duct has been identified by needle aspiration, using the electrocautery the entire pancreatic duct is filleted open from the tail to the neck (1).
Bakes dilator in common bile duct
Head of pancreas being cored out
1
256 Atlas of Gastrointestinal Surgery: Pancreas
Once the duct has been completely filleted open, an attempt should be
made to pass a Bakes dilator through the dilated pancreatic duct and down through the ampulla and into the duodenum. When there is a markedly inflamed, enlarged, and fibrotic head of the pancreas, the
2
Duodenum
Superior mesenteric a. and v.
proximal pancreatic duct is often strictured, and it is impossible to pass a Bakes dilator into the duodenum. These are patients who are particularly good candidates for the Frey procedure. In these
Head of pancreas
patients, progressively more of the head of the pancreas is excised, starting along the course of the opened proximal pancre­atic duct (1). Most of the head of the pancreas can be cored out
Uncinate process
down to the level of the pancreatic duct. Having previously identi-
Bakes dilator
fied the superior mesenteric and portal veins allows one to perform this head resection safely without fear of injury to these venous structures, or to the superior mesenteric artery. If the distal bile duct is involved in the inflammato­ry process and strictured, it is necessary to identify its course prior to the local head resection. If the gall bladder is still in place, it can be mobilized and a biliary Fogarty balloon catheter passed through the cystic duct down through the ampulla into the duodenum. Often, however, a cholecystectomy has been previously performed, and it is necessary to pass a Bakes dilator down through a choledochotom (1, 2). After identifying the course of the common duct, the pancreatic tissue can be resected close enough to the duct often to relieve the obstruction. If this is not possible, then a separate hepaticojejunos­tomy should be performed. If there is no biliary dilatation secondary to a distal stricture, it is usually not essential to identi­fy the intrapancreatic portion of the distal bile duct by insertion of a biliary catheter or Bakes dilator.
When performing local resection of the head of the pancreas, it is essential that the operator keep his hand posterior-
ly on the uncinate process. This prevents the operator from carrying the local head resection too far posteriorly and injur­ing the bile duct. A thin posterior capsule of the uncinate process is left intact (2).
A Roux-en-Y loop 60 cm
in length is then constructed as
Local Pancreatic Head Resection with Lateral Pancreaticojejunostomy (The Frey Procedure) 257
Cored out pancreatic head
previously described. The Roux-en-Y loop is brought up through a rent in the transverse mesocolon and a side-to-side lateral pancreaticojejunosto­my carried out. The inferi­or posterior row is placed first, utilizing multiple, interrupted 3-0 silk Lembert sutures. The inner layer is then run with a 3-0 absorbable synthetic suture material over and over in a locking fashion (3), brought back as the inner
3
Roux-en-Y loop
layer of the superior row of the anastomosis in a Connell fashion.
258 Atlas of Gastrointestinal Surgery: Pancreas
The superior outer layer of the
anastomosis is completed with a series of interrupted 3-0 silk Lembert sutures (4,5).
4
Completed pancreaticojejunostomy
Colon
End-to-side jejunojejunostomy
5
Local Pancreatic Head Resection with Lateral Pancreaticojejunostomy (The Frey Procedure) 259
If the pancreatic duct is only minimally dilated,
the anastomosis can be performed with a single layer of interrupted 3-0 silk sutures with the
Alternate: Duct less than 1 cm in diameter
Pancreas
knots left on the outside (6).
This modification of the Puestow proce-
dure is of particular value when there is a large inflamed of the head of the pancreas. In these instances, the head and uncinate process of the pancreas may not be adequately decom­pressed with just a Puestow procedure, and adding the Frey modification of a local head resection is an excellent idea. Two closed suction Silastic drains are left to the site of the lateral pan­creaticojejunostomy and are brought out through stab wounds in the left upper quadrant. The Roux-en-Y loop is tacked to the rent in the transverse mesocolon with interrupted 3-0 silks. The defect in the small bowel mesentery is closed with a contin-
Duct
Jejunum
6
uous 4-0 silk.
Duodenal Preserving Pancreatectomy for Chronic Pancreatitis (The Beger Procedure)
Operative Indications:
In patients with chronic pancreatitis, and abdominal pain, with a small fibrotic gland with a dilated pancreatic duct, the Puestow procedure is an excellent operation. One should be certain during the performance of the lateral pancreaticoje­junostomy that a Bakes dilator can be passed through the open pancreatic duct down through the ampulla into the duo­denum. If there is an enlarged head of the pancreas, a substantial inflammatory mass, and/or one cannot pass a Bakes dila­tor easily through the proximal pancreatic duct, through the ampulla and into the duodenum, then a local head resection and lateral pancreaticojejunostomy (the Frey procedure) is an excellent operation. Many patients, however, have a very large inflammatory mass in the head of the pancreas but no dilated pancreatic duct. These patients can be treated with the duodenal-preserving pancreatectomy, or the Beger procedure. This operation has gained significant popularity in Europe and, in many areas, is the most frequently performed operation for chronic pancreatitis. It has been slow to catch on in the United States, and is not nearly as frequently performed as the Puestow procedure, the Frey procedure, and the pylorus­preserving pancreaticoduodenectomy. It is an operation that requires a good deal of experience to perform.
Operative Technique:
The abdomen is entered either through a bilateral subcostal or an upper midline incision. The abdomen is first explored for other pathology. The omentum is then removed from the transverse colon, and the neck, body and tail of the gland examined. We prefer to per­form an extensive kocherization, although the originator of the operative procedure does not kocherize the duodenum. This operation is ideally suited for patients with a very large inflammatory mass in the head of the pancreas. The first step in the procedure is to be cer­tain one is not dealing with an adenocarcinoma of the head of the pancreas. One should
Normal sized pancreatic duct
Duodenal Preserving Pancreatectomy for Chronic Pancreatitis (The Beger Procedure) 261
Fibrotic pancreas divided over superior mesenteric v.
Superior mesenteric v.
1
perform needle biopsies if there is any question. After being reassured that one is dealing with chronic pancreatitis, the superior mesenteric vein is identified along the inferior border of the neck of the pancreas and separated from the posterior pancreatic neck. Superiorly, the portal vein is identified along the superior border of the neck of the pancreas, and dis­sected free from the posterior aspect, and connected to the superior mesenteric vein dissec­tion. A Penrose drain is passed underneath the neck of the pancreas, and then the neck of the pancreas is divided with the electrocautery (1).