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7.3 Colour Atlas ofOropharyngeal Diseases
a b
291
c
e
Fig. 7.3 Clinical picture of oropharyngeal diseases. (a) Acute tonsillitis; (b) diphtheria; (c) parenchymatous ton­sillitis; (d) granular pharyngitis; (e) chronic tonsillitis; (f) peritonsillar abscess; (g) retropharyngeal abscess; (h) par­apharyngeal tumour; (i, j) large tonsillar cleft; (k) tonsillar debris; (l, m) acute recurrent tonsillitis; (n) oropharyngeal
d
f
isthmus; (o) B/L—chronic tonsillitis; (p) tonsillar debris; (q) OSMF involving tonsil and anterior tonsillar pillar; (r) lymphoid hypertrophy of base of tongue; (s) acute tonsil­lopharyngitis; (t) tonsillolith; (u) tonsillar debris; (v) phar­yngitis; (w) U/L tonsillar hypertrophy; (x) grade 3 tonsillar hypertrophy; and (y) grade 2 tonsillar hypertrophy
292
7 History andExamination ofOropharynx
g
i
k
h
j
l
Fig. 7.3 (continued)
7.3 Colour Atlas ofOropharyngeal Diseases
293
m
a
o
q
n
p
r
Fig. 7.3 (continued)
294
7 History andExamination ofOropharynx
s
a
u
w
t
v
x
y
Fig. 7.3 (continued)
History andExamination ofLaryngeal andHypopharyngeal Disorders
8
8.1 Symptomatology/ Presentation ofLarynx andHypopharynx
The disorders of the larynx range from simple laryngitis to carcinoma larynx, caused by strain or injury to the vocal cords through excessive talking, throat clearing, coughing, smoking, screaming, singing or speaking too loudly or too softly. The usual presenting symptoms are change of voice, dysphonia, dysphagia, etc. The disor­ders of hypopharynx range from simple reux disorder to hypopharyngeal cancer. The diseases of this region presented mainly with dysphagia or odynophagia.
Usual Symptoms of Carcinoma of Larynx and Hypopharynx
• Hoarseness or other voice changes that persists for more than 2weeks.
• An enlarged lymph node or lump in the neck.
• Airway obstruction, difculty breathing and noisy breathing.
• Persistent sore throat or a feeling that something is in the throat.
• Persisting difculty swallowing (dysphagia).
• Ear pain (referred pain).
8.2 History ofLaryngeal andHypopharyngeal Disorders
8.2.1 Presentation/Chief Complaints/Symptoms ofLaryngeal Disorder
(a) Change of voice—An impairment or change
in voice quality that affects the ability to speak or sing. This can range from altered voice to complete aphonia.
• Type of change of voice (Table8.1)
• Duration of change of voice—The dura­tion of change in voice may be either for short duration or for long duration.
– Acute—acute laryngitis, laryngotra-
cheal reux, vocal cord paralysis, iatrogenic.
– Chronic—vocal cord nodule, vocal cord
polyp, vocal cord cyst, vocal cord benign tumour, laryngeal carcinoma.
• Mode of onset
– Sudden—acute laryngitis, idiopathic,
viral infection, vocal cord paralysis, iatrogenic.
– Gradual—laryngeal tumour (benign or
malignant), vocal cord polyp, Reinke’s oedema.
© The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025 S. K. Kashyap, S. Sagar, Clinical Methods of Otorhinolaryngology, Skull Base & Head Neck Surgery, https://doi.org/10.1007/978-981-96-1765-4_8
295
296
Table 8.1 Types of changes with causes
Type of voice Denition Causes Hoarseness of voice It is dened as change in voice or rough and
unpleasant voice due to vocal cord lesion leading to faulty approximation of vocal
cords Breathy voice It may suggest poor vocal cord function Adductor paralysis Raspy voice It may indicate vocal cord thickening due to
swelling, inammation Shaky voice or soft voice It may suggest trouble getting enough
breathing force or air Hot potato voice It is a term for a defect of resonance in which
the speech has mufed quality, fancifully
likened to a person speaking with a hot
potato in mouth
Table 8.2 Differential diagnosis of hoarseness of voice with other symptoms
Associated symptoms with hoarseness of voice D/D Pain Acute laryngitis, trauma to larynx Dysphagia Supraglottic growth, retropharyngeal abscess
Odynophagia, +/ pain, fever
Cough +/ fever
H/o smoking +/, stridor, dysphagia, neck swelling
8 History andExamination ofLaryngeal andHypopharyngeal Disorders
Carcinoma of voice, vocal cord polyp, vocal cord paralysis, vocal cord papilloma, laryngitis
Infection, a chemical irritant, voice abuse
COPD
Growth over base of tongue Epiglottitis Peritonsillar abscess
Acute laryngopharyngitis
Vocal cord paralysis
Carcinoma larynx
Table 8.3 Causes of hoarseness of voice
Inammation/oedema/ infection Structural Neurological Others
Laryngitis Allergy Laryngopharyngeal reux Reinke’s oedema, epiglottitis
• Associated symptoms and history—pain, dysphagia, dyspnoea, GERD symptoms, thyroid surgery, fever, odynophagia, neck pain, smoking.
Vocal cord nodule, Polyp, cyst, papilloma Vocal cord benign tumour Laryngeal carcinoma, thyroid carcinoma, hypopharyngeal carcinoma
U/L vocal cords paralysis, B/L vocal cord paralysis
Scarring of vocal cords Injury to vocal cord Injury to RLN
(c) Dysphonia (difculty in phonation)
• Types of dysphonia – Muscle tension dysphonia—Muscle
tension dysphonia is a ‘functional dys­phonia’, whereby a pattern of muscle
Differential Diagnosis of Hoarseness of Voice with Associated Symptoms (Table8.2)
use develops from irritants, laryngitis or even stress, and among other condi­tions. The voice changes may be dif-
Causes of Hoarseness of Voice (Table8.3)
ferent in different individuals (Table8.4).
(b) Aphonia (total loss of voice)—It is pre-
sented as unable to speak or unable to speak above whisper. It may be either hysterical or organic (B/L vocal cord paralysis, paralysis of respiratory muscles, glottic spasm).
– Puberphonia (mutational Falsetto, func-
tional falsetto, incomplete falsetto, ado­lescent falsetto, pubescent falsetto)—It is functional voice disorder character­ized by habitual use of high pitch voice
8.2 History ofLaryngeal andHypopharyngeal Disorders
Table 8.4 Symptoms of muscle tension dysphonia
• Voice that sounds rough, hoarse, gravelly or raspy.
• Voice that sounds weak, breathy, airy or is only a whisper.
• Voice that sounds strained, pressed, squeezed, tight or tense.
• Voice that suddenly cuts out, breaks off, changes pitch or fades away.
• Voice that ‘gives out’ or becomes weaker the longer the voice is used.
• Pitch that is too high or too low.
• Difculty singing notes that used to be easy.
• Pain or tension in the throat when speaking or singing.
• Feeling like the throat is tired when speaking or singing.
Table 8.5 Types of spasmodic dysphonia
Type of spasmodic dysphonia Denition Adductor spasmodic dysphonia This is the most common type of spasmodic dysphonia. In this type of
dysphonia, words are often cut off or are difcult to start because of muscle spasm. Therefore, speech may be choppy, strained, or strangled and full of effort. If the spasm is absent, voice sounds normal while laughing, crying or shouting. Stress often makes spasm more severe
Abductor spasmodic dysphonia The voice often sounds weak and breathy. The spasm is usually absent during
laughing, crying and shouting
Mixed spasmodic dysphonia This is usually rare and mixed of both types
297
after puberty. The voice may be breathy, rough and lacking in power. It is pre­sented with complaint of inability to shout or compete with background noise and vocal fatigue. Male has mutational falsetto, and female has adolescent tran­sitional dysphonia.
– Spasmodic dysphonia—It causes voice
breaks and can give the voice a tight, strained quality, occasional breaks in their voice that occur once every few sentences. Usually, however, the disor­der is more severe and spasms may occur on every other word, making a person’s speech very difcult for others to understand. Symptoms of spasmodic dysphonia range from mild to severe and become more frequent over time (Table8.5).
• Duration of dysphonia – Acute—psychological, neurological,
aphonia.
– Chronic—spasmodic dysphonia.
• Time of onset – Puberty—puberphonia. – Adult onset—muscle tension dyspho-
nia, spasmodic dysphonia.
• Mode of onset of dysphonia – Sudden—psychological, neurological. – Gradual—spasmodic.
• Associated symptoms/history of neuro-
logical disorder, psychological disorder, vocal misuse or overuse, throat dehydration.
(d) Pain in throat—This is an unpleasant sen-
sory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.
• Type of pain – Burning/stabbing/shooting—neuro-
pathic pain—chronic laryngopharyn­geal neuropathy, superior laryngeal neuralgia, carcinoma larynx.
– Inammatory pain—laryngitis, epiglot-
titis, supraglottitis.
– Pain with no obvious organic origin—
functional pain.
• Duration – Acute—acute laryngitis, supraglottitis,
acute epiglottitis.
– Chronic—rheumatoid arthritis, laryn-
geal carcinoma, perichondritis.
• Severity
– Mild—acute laryngitis.
298
H/o alcohol intake and
8 History andExamination ofLaryngeal andHypopharyngeal Disorders
– Moderate—acute supraglottitis, rheu-
matoid arthritis.
– Severe—acute epiglottitis, laryngeal
carcinoma.
• Mode of onset – Sudden—acute laryngitis, trauma, acute
supraglottitis, acute epiglottitis.
– Gradual—rheumatoid arthritis, laryn-
geal carcinoma, perichondritis.
• Time of pain—pain during phonation,
pain after phonation, pain at the initiation of swallowing, after swallowing.
• Associated symptoms with pain are
hoarseness of voice, dysphagia, dys­pnoea, GERD odynophagia, hoarseness of voice.
Rare causes of throat pain
Superior laryngeal neuralgia—It presents as
pain paroxysms, lasting for minutes or hours, triggered by swallowing, straining voice or head turning. A trigger point is present on the lateral aspect of the throat overlying the thyrohyoid membrane.
Chronic laryngopharyngeal neuropathy— Laryngeal irritation such as throat irritation, dysphonia, foreign body sensation in the throat, stridor and especially chronic cough.
Superior cornu syndrome—It is abnormal indentation of superior cornu of thyroid cartilage that causes dysphagia, odynophagia or throat pain.
(e) Dysphagia (difculty in deglutition)
• Duration – Acute—acute epiglottitis, acute supra-
glottitis, ALTB.
– Chronic—supraglottic tumour, neuro-
logical.
• Mode of onset – Sudden—infection, stroke (neurologi-
cal).
– Gradual—supraglottic growth.
• Progression – Progressive—supraglottic growth. – Non-progressive—stroke.
• Associated symptoms and history of pain,
smoking, alcohol + smoking, FB inges­tion, GERD.
(f) Dyspnoea (difculty in breathing)—The
difculty in breathing or dyspnoea in laryn­geal disorder or tumour disorders is most of
time due to involvement of larynx or involve­ment of RLN.
• Duration—It can be acute if it is present for short duration or chronic.
– Acute—Acute dyspnoea is caused by
acute epiglottitis, acute supraglottitis, angioneurotic oedema.
– Chronic—laryngeal papillomatosis,
vocal cord polyp, growth, Reinke’s oedema.
• Severity—It can be mild, moderate and severe.
• Associated symptoms—change of voice, neck swelling, dysphagia, odynophagia, throat pain, drug or food allergy.
(g) Stridor (Sound of Breathing)—It is dened
as audible sound heard without stethoscope during either in inspiration, expiration or in both phases of respiration. In cases of carci­noma of larynx or mass lesion in larynx, it is inspiratory.
• Duration
Acute—acute epiglottitis, acute
supraglottitis.
– Chronic—laryngeal papillomatosis, vocal
cord polyp, benign tumour of larynx.
• Mode of onset
– Sudden onset—acute epiglottitis.
– Gradual onset—benign tumour of lar-
ynx, vocal cords oedema.
• Associated symptoms
– Hoarseness of voice—carcinoma lar-
ynx, benign tumour of larynx.
– Odynophagia—epiglottitis, supraglotti-
tis.
– Cough
– Cough with expectoration—tuberculo-
sis larynx, tuberculosis.
– Dysphagia—carcinoma hypopharynx,
CA cervical oesophagus.
smoking—carcinoma.
– Associated symptoms.
(h) Cough—The dry cough is common in laryn-
geal disorders.
• Dry cough, wheezing, throat tightness and hoarseness—vocal cord dysfunction, asthma.
8.2 History ofLaryngeal andHypopharyngeal Disorders
299
• Cough triggers by talking—muscle ten­sion dysphonia.
• Cough during swallowing—vocal cords paralysis.
• Chronic persisting cough with paradoxi­cal vocal fold movement and extratho­racic airway hyperresponsiveness.
• Chronic cough, throat clearing, FB sensa­tion in throat—irritable larynx syndrome (Table8.6).
• Associated symptoms with cough h/o ACE inhibitor, bronchitis, GERD, postna­sal drip.
(i) Neck swelling
• Site—larynx and lymph node enlargement in levels 3, 4, 5 and 6.
• Mode of onset—it can be gradual or sudden.
• Progression
– Progressive—nodal metastasis, tubercu-
lar lymphadenitis, acute lymphadenitis.
– Non-progressive.
• Associated symptoms—dysphagia, change of voice.
(j) Evaluation of speech and its disorders
Speech—Speech is the process of produc­ing specic sounds that convey meaning to the listener. Speech is one of the main ways in which people communicate their thoughts, feelings and ideas with others. The act of speaking requires the precise coordination of multiple body parts, includ­ing the head, neck, chest and abdomen.
• Types of speech disorder include stutter­ing, apraxia and dysarthria.
Stuttering—Stuttering refers to a
speech disorder that interrupts the flow of speech, whereas some people may also find that certain words or sounds can make a stutter more pro­nounced. People who stutter can experience the following types of disruption.
Repetitions occur when people involuntarily repeat sounds, vowels or words. Blocks happen when people know what they want to say but have dif­culty making the necessary speech sounds. Blocks may cause someone to feel as though their words are stuck. Prolongations refer to the stretching or drawing out of particular sound.
Types of Stuttering
Developmental stuttering affects
young children who are still learning speech and language skills. Genetic fac­tors signicantly increase a person’s likelihood of developing this type of stutter. Neurogenic stuttering occurs when damage to the brain prevents proper coordination between the different regions of the brain that play a role in speech.
Speech disorders—A speech disorder refers to any condition that affects a per­son’s ability to produce sounds that create words. It can affect a person’s self-esteem and their overall quality of life. There are many possible causes of speech disorders, including muscle weakness, brain inju­ries, degenerative diseases, autism and hearing loss.
Associated symptoms/history—Stutter­ing can cause both behavioural and physical symptoms that occur at the same time like tension in the face and shoulders, rapid blinking, lip tremors, clenched sts, sudden head movements, h/o aggravating factors (stress, excite­ment or frustration).
Verbal apraxia (acquired apraxia of
speech, dyspraxia)—It is motor speech
300
Table 8.6 Different laryngeal causes of dry cough
Irritable larynx syndrome Vocal cord paralysis Muscle tension dysphonia Upper respiratory infection with cough
Reux Postnasal drainage Allergens (e.g. tree, mould, pollen, pet dander) Cigarette smoke or other kinds of smoke Odours (e.g. perfume, hairspray) Food sensitivities Harsh chemicals/cleaners Cold air or hot/humid air Strong emotions (e.g. anxiety, stress) Hyperfunction of the muscles of the vocal mechanism
8 History andExamination ofLaryngeal andHypopharyngeal Disorders
Change of voice H/o trauma H/o thyroid surgery
Dysphonia Pain while phonation
disorder. It refers specically to the impairment of motor skills that affect an individual’s ability to form the sounds of speech correctly, even when they know which words they want to say. Verbal apraxia can be presented
with these symptoms. Have trouble imitating and saying sounds on your own. Patient may add new sounds, leave sounds out or say sounds the wrong way. Patient is able to say something the right way one time but the wrong way the next time. Patient moves his tongue and lips to get them into the right place as he tries to say sounds. This is called groping. Speak more slowly. Be able to say things that person said all the time—like ‘Hello’ or ‘How are you?’—without much trouble. This is called automatic speech.
Not be able to say any sounds at all. This may happen in severe cases.
Dysarthria—It occurs when damage to
the brain causes muscle weakness in a
person’s face, lips, tongue, throat or
chest. Muscle weakness in these parts
of the body can make speaking very
difcult. It is presented with slurred
speech, mumbling, speaking too slowly
or too quickly, soft or quiet speech, dif-
culty moving the mouth or tongue.
Presentation of speech disorders—The symptoms of speech disorders vary widely depending on the cause and severity of the
disorder. People can develop multiple speech disorders with different symptoms.
– Repeating or prolonging sounds – Distorting sounds – Adding sounds or syllables to words – Rearranging syllables – Having difculty pronouncing words
correctly
– Struggling to say the correct word or
sound – Speaking with a hoarse or raspy voice – Speaking very softly
• Duration—it can be short duration or long duration.
• Mode of onset—sudden or insidious.
• Associated symptoms and past h/o stroke, head injury, neck injury, dementia, autism, Down syndrome, head & neck cancer, hearing loss, ear infection, Huntington’s disease, Parkinson’s disease or amyotrophic lateral sclerosis. Premature baby and low birth weight should be ruled out.
8.3 History/Presentation ofHypopharyngeal Disease
1. Chief Complaints/Symptoms of Hypopharyn-
geal Disorders
(a) Dysphagia (difculty in swallowing)—
Patients frequently report food sticking in the upper oesophagus or upper throat. This is because the hypopharynx is involved in the coordination of the swal­lowing function around the larynx.