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Acknowledgments
We are deeply indebted to the many dedicated people who have given of themselves to complete the twelfth edition of Applied Therapeutics: The Clinical Use of Drugs. We are grateful to our contributing authors who have worked tirelessly and with resolve to provide the highest quality of work, while providing vital services to patients during the pandemic, along with numerous responsibilities as educators, clinicians, and researchers. We are grateful for the exceptional work of our 28 section editors, who provided critical feedback necessary both in the organizational structure of the textbook and in the individual editing of chapters; without their dedication and support, this edition would not have been possible. We sincerely thank the past editorial team of Applied Therapeutics, with special thanks to Dr. B. Joseph Guglielmo for his guidance and support and contributions to this textbook.
The team from Wolters Kluwer, Matt Hauber, Deborah Bordeaux, Kelly Horvath, Venugopal Loganathan, Sean Hanrahan, and Susan Thomas, deserves special recognition for their efforts. Their exceptional patience, attention to detail, and guidance have been critical to the success of this project. We sincerely thank Catherine Ott (project management) and Subhash Nataraj (production) for their assistance in completing this edition. Most importantly, we wish to acknowledge the love, understanding, and unwavering support of our spouses and families. They selflessly gave to us early mornings, late nights, weekends, and vacation time that we spent writing and editing.
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Consistent with past editions, we continue to dedicate our work to our students who inspire us and to the many patients we have been privileged to care for and who have taught us invaluable lessons. We also dedicate the twelfth edition to those health professions educators and clinicians who have served as pioneering leaders and role models in the delivery of patient-centered care using team­based approaches.
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Additional Resources
The twelfth edition of Applied Therapeutics: The Clinical Use of Drugs includes additional resources for both instructors and students, available on the book’s companion website at
http://thepoint.lww.com/AT12e.
STUDENT RESOURCES
Students who have purchased Applied Therapeutics: The Clinical Use of Drugs, Twelfth Edition, have access to the following additional
resources for each chapter:
A full online reference list for that chapter
INSTRUCTOR RESOURCES
Approved adopting instructors will be given access to the following additional resources:
Interprofessional Education (IPE) Case Studies and Answer Guides
Each chapter will map which NAPLEX competency statements are addressed within it, which will be a helpful resource for instructors.
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Section Editors
Mary G. Amato, PharmD, MPH, FCCP, BCPS
Professor Emerita of Pharmacy Practice Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Michael C. Angelini, PharmD, MA, BCPP
Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Judith L. Beizer, PharmD, CGP, FASCP
Clinical Professor Department of Clinical Pharmacy Practice College of Pharmacy & Allied Health Professions St. John’s University Jamaica, New York
Snehal H. Bhatt, PharmD, BCPS
Associate Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences
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Clinical Pharmacist Beth Israel Deaconess Medical Center Boston, Massachusetts
Michael G. Carvalho, BS, PharmD, BCPP
Professor Emeritus of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Judy W. Cheng, PharmD, MPH, BCPS, FCCP
Professor and Chair School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
R. Rebecca Couris, PhD, RPh
Professor of Nutrition Science and Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Elizabeth Anne Farrington, PharmD, FCCP, FCCM, FPPA, BCPS, BCNSP, BCPPS
Clinical Pharmacist–Pediatrics Department of Pharmacy Novant Health New Hanover Regional Medical Center Wilmington, North Carolina
Steven Gabardi, PharmD, BCPS, FAST, FCCP
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Abdominal Organ Transplant Clinical Specialist Brigham and Women’s Hospital Assistant Professor of Medicine Harvard Medical School Mass General Brigham Boston, Massachusetts
Jennifer D. Goldman, PharmD, CDCES, BC-ADM, FCCP
Professor of Pharmacy Practice Clinical Pharmacist, Well Life School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Christy S. Harris, PharmD, BCOP, FHOPA
Associate Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Timothy R. Hudd, BS, PharmD, AE-C
Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Susan Jacobson, MS, EdD, RPh
Associate Professor of Pharmacy Practice School of Pharmacy—Boston
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Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Katie Kiser, PharmD, BCACP
Associate Professor of Pharmacy Practice Director, Interprofessional Education Ambulatory Care Clinical Specialist–NHC Farragut South College School of Pharmacy Knoxville, Tennessee
Maria Kostka-Rokosz, PharmD, RPh
Assistant Dean of Academic Affairs Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Susan A. Krikorian, MS, PharmD
Professor Emerita of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Trisha LaPointe, PharmD, BCPS, FASHP
Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Michele Matthews, PharmD, BCACP, CPE, FASHP
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Professor and Vice Chair School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Susan L. Mayhew, PharmD
Dean and Professor Pharmacy Practice Appalachian College of Pharmacy Oakwood, Virginia
Oussayma Moukhachen, PharmD, BCPS, BCCCP
Associate Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Kamala M. Nola, PharmD, MS, FAPhA
Associate Dean of Academic Affairs and Professor Department of Pharmacy Practice Lipscomb University College of Pharmacy Nashville, Tennessee
Dorothea Rudorf, PharmD, MS (Germany), RPh
Professor of Pharmacy Practice School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
David Schnee, PharmD, BCACP
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Professor and Vice Chair School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
Carrie A. Sincak, PharmD, BCPS, FASHP
Associate Dean for Clinical Affairs Professor of Pharmacy Practice Midwestern University Chicago College of Pharmacy Downers Grove, Illinois
Adrian Wong, PharmD, MPH, FCCM, BCCCP
Adjunct Associate Professor School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
G. Christopher Wood, PharmD, FCCP, FCCM, BCCCP
Professor Department of Clinical Pharmacy and Translational Science College of Pharmacy University of Tennessee Health Science Center Memphis, Tennessee
Kathy Zaiken, PharmD
Professor of Pharmacy Practice Director, International Pharmacy Residency Program School of Pharmacy—Boston Massachusetts College of Pharmacy and Health Sciences
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Boston, Massachusetts
Caroline S. Zeind, PharmD
Vice President for Academic Affairs/Provost Professor of Pharmacy Practice Academic Affairs Massachusetts College of Pharmacy and Health Sciences Boston, Massachusetts
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