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Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_141_библиотеки_им_акад_М_И_Перельмана

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70 Scabies, Scabies Mites, Scabies Mite Burrows
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Fig. 70.21–70.89 (continued)
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Fig. 70.21–70.89 (continued)
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Fig. 70.21–70.89 (continued)
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Fig. 70.21–70.89 (continued)
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Fig. 70.21–70.89 (continued)
cal and epidemiological studies, and the development and practical application of a commercialized mite diagnostic kit that can diagnose mites simply and quickly is desperately needed. Scabies was additionally designated as a “neglected tropical disease” by WHO in 2017, and more understanding of its disease burden is currently needed. However, there were limitations in interpreting research and epidemiological survey results because standardized test methods or screen-
ing procedures for diagnosis have not been established, but in 2018, The International Alliance for the Control of Scabies (IACS) developed agreed mite diagnostic criteria.
I recently read an article by a blogger. He said, “in Korea, when things aren’t going well, people sometimes say, ‘Scabies stick to my luck.’ Actually, I didn’t know what ‘scabies‘was, but after suffering from itching for several months and being diagnosed with scabies, I realized what a
70 Scabies, Scabies Mites, Scabies Mite Burrows
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Figs. 70.90–70.92 Scabies mites and burrows—500 times magnied image
Figs. 70.93 and 70.94 Classical scabies
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Figs. 70.95 and 70.96 Crusted scabies (Norwegian scabies)
70 Scabies, Scabies Mites, Scabies Mite Burrows
Figs. 70.97 and 70.98 Canine scabies
Figs. 70.99 and 70.100 Vesicular scabies
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Figs. 70.101 and 70.102 Nodular scabies
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Figs. 70.103 and 70.104 Scabies incognito
Fig. 70.105 In women, scabies infestation tend to occur at older ages
Fig. 70.106 Scabies in the elderly
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70 Scabies, Scabies Mites, Scabies Mite Burrows
terrible expression.” Even if all the mites are exterminated, it can take about 6weeks for hypersensitivity symptoms and signs to be resolved, so it is suggested that treatment failure should not be determined until at least 6weeks after treat­ment is completed. Most cases of treatment failure are due to inappropriate treatment or poor compliance with treatment, but sometimes differential diagnosis should be considered. In developing countries, differential diagnosis should include pruritic skin diseases such as psoriasis, atopic dermatitis, and lichen planus, and if there are blisters, bullous pemphigoid and dermatitis herpetiformis should be considered. In infants and young children, differential diagnoses such as Langerhans cell histiocytosis, papular urticaria, and infantile acropustulosis should be made. In tropical environments, it is important to differentiate from pyoderma that occurs with­out scabies. Norwegian scabies need to be differentially diagnosed from diseases that show hyperkeratosis such as psoriasis, seborrheic dermatitis, Darier’s disease, and palmo­plantar keratoderma. Additionally, it should be remembered that double infections such as scabies and pediculosis, or scabies and syphilis, may occasionally occur. In sexually active patients, tests for sexually transmitted diseases, includ­ing AIDS, must be added. With the recent increase in atypi­cal clinical manifestations of scabies and the resulting delay in diagnosis and misdiagnosis, it is always necessary to keep in mind the possibility of scabies in patients with persistent and severe itching that is resistant to treatment.
Scabies improves within a few weeks with early diagnosis and appropriate treatment. Nodular scabies heals in about 3 months in 80% of patients, but sometimes lasts up to a year. If left untreated for several weeks or months, it not only spreads to those around but also suffers from complications. The complications of scabies and its secondary effects can be a huge burden on public health, but they are not yet gener­ally well recognized. In private clinics, if scabies medication is administered without an accurate diagnosis, it can be unclear how long to use scabies medication for ongoing itch­ing, so it is essential to make an effort to directly conrm the scabies mite or scabies mite burrow. The two drugs most commonly used worldwide for the treatment of scabies are topical permethrin (a synthetic pyrethroid insecticide) and
oral ivermectin (an anti-parasitic macrocyclic lactone antibi­otic), both of which are similarly effective and usually well tolerated. In Korea, since oral scabies medication, ivermec­tin, is not yet produced/distributed, it is important to choose an appropriate topical application that can eradicate scabies mites and all people who have had physical contact, includ­ing family members, should be treated together. Along with the topical application of anti-scabies agents, oral antihista­mines and mild topical steroids are needed to treat dermatitis caused by allergic reactions to scabies mite excrement. If the skin rash is severe and does not improve with topical treat­ment alone, oral steroids can be administered for 1–2weeks, and if there is a secondary bacterial infection, appropriate antibiotics should be administered concurrently.
The family who came today had been receiving treatment for itching for quite some time, and their skin symptoms had repeatedly improved and worsened without knowing the cause. When I looked at the palms and soles of my 8-month­old baby, I found a lot of scabies mite burrows. I showed the scabies mite burrows and the scabies mites hiding at the end of the burrows and showed the mite burrows and mites between the ngers of the mother and father, and they were surprised and said, “Everyone said it was atopy and pre­scribed medicine, but it’s refreshing to conrm the scabies mites like this!” Today, my heart is really refreshing.
For reference, the most interesting part in the history of human scabies mite discovery is that Simon François Renucci saw scabies mites without a magnifying glass and specied their location on the skin. He extracted the mites directly from the patient’s skin and xed them at the end of the needle and raised them high in the sky. His success was because he knew the previous report that scabies mites are not found in vesicles, but at the end of the scabies mite bur­row, which others overlooked. Thus, the existence of human scabies mites was proven, and the question was nally answered. This fact was announced in the 1834 Gazette des hôpitaux, and Renucci’s 1835 paper included extensive information on scabies symptoms, the shape of scabies mite burrows, and how to accurately extract scabies mites. Also, the articial transmission of scabies mites was experimented by himself (Fig.70.107).