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132 Atlas of Complicated Abdominal Emergencies
Injury to the distal part of the pancreas in the tail
region necessitates distal pancreatectomy with closure of pancreatic stump and drainage of the area. Spleen preservation can be attempted if patient’s condition allows.
In ductal injuries, especially combined injuries
of the head of pancreas and duodenum, integrity of the distal CBD and ampulla of Vater on cholangiogram will dictate the operative procedure. Intact duct and ampulla requires simple repair and drainage or repair and pyloric exclusion.
Pyloric exclusion is widely adopted in the
management of Grade III and IV combined pancreaticoduodenal injuries. The technique involves temporary diversion of enteric fl ow away from the injured duodenum by closure of the pylorus and creation of a gastroenterostomy.
Closure of the injured area over a T-tube in
combined injuries when D2 is involved has also been advocated.
Injury to the body of the pancreas with disruption
of the pancreatic duct may necessitate central pancreatectomy (See Fig. 8).
{ Lesser sac is entered by opening the gastrocolic
ligament.
{ Careful assessment of the injured pancreatic
tissue and surrounding structures such as the
duodenum is essential to plan the next step of the operation.
{ Disruption of the pancreatic duct at the neck and
body may necessitate central pancreatectomy but, recently, PD disruption has been successfully treated conservatively.
{ SMV-PV tunnel is created with careful dissection
of the neck of pancreas. Pancreatic neck is transected using GIA stapler (with or without buttress material).
{ Further dissection of the pancreatic body is
performed from medial-to-lateral. Vessels con­nected to the pancreatic tissue are progressively ligated and divided.
{ Pancreatic neck and part of the body are transected
with cold-blade after adequate margin is achieved with all devitalised and unhealthy tissue removed.
{ Bleeding from the cut surface of pancreas is
secured with prolene 5/0 interrupted sutures.
{ A roux loop of jejunum is brought up in retro -
colic manner without tension to facilitate PJ anastomosis.
{ Options of anastomosis are dependent on the
surgeon’s choice. Preferably, the surgeon should perform the type of pancreatico-enteric anastomo­sis that they are most familiar with at most times.
{ In single-layer PJ, both anterior and posterior
layer of anastomosis can be performed using PDS sutures. The sutures will be placed from the pan­creatic side, parenchyma-to-capsule, to bowel side, seromuscular layer. Pancreatic stent is usually not required.
{ In double-layer anastomosis, the outer posterior
layer can be performed using prolene 4/0 suture in continuous manner while the inner posterior and anterior layer can be completed using PDS 5/0 sutures in interrupted manner. Pancreatic stent can be secured in the duct-to-seromucosa anastomosis if necessary. The outer anterior layer of the PJ can be completed with prolene 4/0 sutures.
Figure 8.
Central pancreatectomy and reconstruction.
In fewer than 10% of cases, severe injury
with unreconstructable injury to the duct or ampulla of Vater or duodenum would require pancreaticoduodenectomy (Whipple procedure).
Chapter 14 Surgical Management of Bile Duct & Pancreatic Emergencies 133
Some centres would advocate the use of
somatostatin or its analogue (octreotides) in order to reduce pancreatic secretion. However, the evidence for administration of this pharmacological agent is controversial at the moment.

E) ERCP Perforation

{ Incidence of ERCP-related perforation is rare
(about 1%).
{ Types of ERCP injury can be classified as
follows:
Type I — Lateral duodenal wall injury (Or
medial injury)
Type II — Injury to the sphincter of Oddi Type III — Ductal injury Type IV — Retroperitoneal air only
{ Type I injuries tend to be large and remote from
the ampulla of Vater. Persistent contrast leak in the retroperitoneal and/or intraperitoneal spaces may be evident on scans. Exploratory laparotomy and repair of the damaged structures is necessary.
{ Type II usually represents perivaterian injuries
with varied severity, but usually the injury is discrete and less likely to require surgery.
{ Type III is usually due to distal bile duct injury
related to wire of basket instrumentation near the
obstructing entity (e.g. stones). The site of injury is usually small. Conservative management is often possible.
{ Type IV injuries are probably related to the use of
compressed air to maintain patency of a lumen and are not true perforations. Surgical interven­tion is not required.
{ In short, the surgical indications after ERCP-
related duodenal perforation are as follows:
Large amount of contrast extravasation at
the time of ERCP (defi ned as incomplete dissipation of contrast after one minute on follow-up plain fi lm). If the contrast dissipated after one minute, it may represent small contrast extravasation and a repeat Gastrografi n study should be performed four to six hours later. If contrast extravasation is noted, surgical exploration should be done.
Any follow-up scans showing fl uid collection
in the retroperitoneal or peritoneum consistent with perforation, not pancreatitis.
Documented ERCP perforation with chole-
lithiasis, choledocholithiasis or retained hardware.
Massive subcutaneous emphysema after ERCP
with what appears at endoscopy to be a large duodenal diverticulum.
Failure of nonsurgical management.
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Chapter 15
Laparoscopic Drainage of Liver Abscess
Stephen Chang Kin Yong* and Liza Tan Bee Kun

I. Introduction

In the majority of cases, the aetiology of liver abscess remains unknown (cryptogenic). In patients with a known aetiology, ascending infection from choledocholithiasis is the most common source of liver abscess. In the West, malignancy of the head of pancreas or of bile ducts lead­ing to biliary sepsis is a common cause of liver abscesses.
In the authors’ institutional experience, Klebsiella pneumoniae and Escherichia coli were the most common organisms isolated; 9.2% were amoebic in origin. Diabetes mellitus was associated with 45.5% of these patients.
The majority of the abscesses are found in the right lobe of the liver. The segmental distribution based on the authors’ institutional experience is shown in Fig. 15.1. 97.7% of abscesses are solitary.
II. Management Strategy for Liver
Most liver abscesses can be treated by intravenous antibiotics and percutaneous drainage without general anaesthesia. Nevertheless, a proportion of patients with complicated abscess require surgical drainage.
Abscesses
Figure 15.1.
Location of abscesses.
*K.Y. Chang, MBBS, MRCSED, MMed (Surg), FRCS (Gen Surg), FAMS, Associate Professor, YLL School of Medicine, National University of Singapore, Senior Consultant, Research Director, Division of Hepatobiliary and Pancreatic Surgery, Liver Transplant Program, National University Health System, Singapore.
B. K. Tan, MBBCh, BAo (Nul), MRCS (lve), Department of Surgery, University Surgical Cluster, National University Hospital, Singapore.
135
136 Atlas of Complicated Abdominal Emergencies
In the authors’ experience, surgical drainage can usu­ally be achieved by a laparoscopic technique described as follows:
Preoperative Preparation
1. Ensure adequate infusion of fluids and blood components to restore and maintain blood volume and coagulation ability.
2. Broad-spectrum antibiotics with a view to stream­lining it to targeted therapy based on culture results from blood or from the drained pus.
3. Ensure patient’s condition is safe for general anaesthesia.
4. Informed consent with attention to the possible need of more than one intervention.
III. Operative Procedure Via
Laparoscopic Approach
a. Position
The patient is prepared in the “French position”
(Fig. 15.2), which is a supine position with both
thighs abducted, knees straightened and soles supported. In such a position, the patient can be placed in a reverse Trendelenburg position to allow bowels to be displaced towards the pelvis and the patient prevented from sliding off the operating table.
The lower limbs must be abducted enough to permit the surgeon to position himself between them.
Port Siting
A 10-mm transumbilical incision is made for the camera port. Two 5-mm ports are placed along the midclavicular line cephalad to the camera port (Fig. 15.3).
b. Diagnostic laparoscopy
After a thorough inspection of the abdominal
organs in a systemic fashion, the camera is focused onto the liver.
Note: The common primary diseases to look for
include appendicitis, diverticulitis, cholecystitis and pelvic inflammatory diseases.
Figure 15.2.
Positioning of the patient.
Figure 15.3.
Port sites.
Chapter 15 Laparoscopic Drainage of Liver Abscess 137
c. Intra-operative ultrasound
The 10-mm telescope is exchanged for a 5-mm
telescope and inserted through one of the 5-mm ports. A 10-mm laparoscopic ultrasound is intro­duced through the 10-mm port and a systematic examination of the liver is performed (Fig. 15.4).
The aims of performing the ultrasound are:
i. To confirm the position of the abscess. ii. To identify the site on the liver closest to the
abscess, i.e. the site where the abscess is “point­ing”, which usually serves as the site of initial parenchyma entry. The depth at this point is noted.
Figure 15.4.
Performing laparoscopic ultrasound.
iii. To determine if the abscess is septated. iv. To locate any other smaller abscesses that may not
have been visible on preoperative scans.
v. To verify that no major vasculature crosses the
path of drainage, i.e. from the site of parenchyma entry to the abscess cavity.
vi. To exclude Hydatid cyst, which is characterised
by the presence of daughter cysts within the cav­ity. This is a relative contraindication to laparo­scopic surgical drainage.
d. Drainage procedure
Having completed the ultrasound examination
and determined the most suitable site of paren­chyma entry, the surface of the liver at this site is scored with diathermy to serve as a marker. The laparoscopic u ltrasound probe is then withdrawn and the 5-mm telescope is replaced by the 10-mm telescope. An aspirator is introduced through one of the 5-mm working ports and a hook with dia­thermy is introduced through the other. The site of parenchyma entry is further diathermised to coagulate a 1 cm diameter area of liver and induce sufficient “dimpling” of the liver. The power of the diathermy is then increased to 50, and the hook is advanced through the site of entry towards the abscess cavity keeping the power of the
138 Atlas of Complicated Abdominal Emergencies
Figure 15.5.
Breaking down the septa using the aspiration catheter.
diathermy activated all the time. When the abscess cavity is reached, purulent material will be released. The pus is aspirated and sent for culture and sensitivity. The aspiration catheter is also used to gently break down the septa within the abscess if these were found during the ultrasound examination (Fig. 15.5). The cavity is then washed with saline.
Precautionary note
i. It is important to coagulate a 1 cm diameter
around the site of entry before attempting to enter the abscess cavity. This will reduce the likelihood of tearing the liver and induce bleeding at this site when the aspiration catheter is introduced later to break down the septa. The coagulated “capsule” at the surface will resist tearing of the liver at the point of entry and serves as point of pivoting for the instrument movements.
ii. Advancement of the hook with diathermy into the
abscess cavity must be performed slowly in a con­trolled manner to allow the liver parenchyma with its microvasculature to coagulate sufficiently to reduce the amount of blood loss.
iii. The aspirator must be position close to the site of
entry in anticipation of the exit of the pus to reduce contamination to the rest of the abdominal cavity. The prior knowledge obtained during the ultrasound step with regards to the depth of the abscess helps the surgeon to judge when the abscess wall is about to be breached.
Special tricks!
Occasionally there may be bleeding encountered while trying to break down the septa within the abscess cavity. The important point then is to stop aspirating! This will allow the pneumo-peritoneal pressure to build up again, which will then serve as tamponade to further bleeding!
e. Placement of drains
A large-bore drain (14 fr) is introduced through
the 5-mm port into the cavity. A second similar drain is placed into the sub-hepatic space near the abscess cavity. The ports are then removed.
Special tricks!
The placement of the first drain into the cavity may be guided by another grasper introduced via the other 5-mm port. But given that there are only two working ports, the placement of the second drain may be difficult. The trick is to use the port itself to direct the position of the drain towards the subhepatic space!

IV. Postoperative Management

i. Post-operatively, the patient is monitored for
signs of intra-peritoneal bleeding such as tachy­cardia, hypotension, generalised abdominal pain and significant bloody drainage from the drains.
ii. The abscess catheter may be flushed daily with
10 mL of sterile saline to prevent it from being blocked.
iii. Appropriate antibiotics are started after obtaining
the culture results.
iv. A CT scan may be repeated two weeks later to
check that no other abscesses have developed and that the drains are still in appropriate posi­tion. It is possible to observe a reduction in size of the abscess cavity, but it is unlikely to contract fully.
Chapter 15 Laparoscopic Drainage of Liver Abscess 139
v. The timing of drain removal varies. The authors’
preference is that there must be absence of clini­cal signs of active infection, radiological evi­dence of contraction of the abscess cavity and absence of any partially necrotic liver tissue in the cavity.

Special situations

i. Abscesses in segments 7, 8
When the abscess is mainly in the superior seg-
ments of the right lobe, i.e. segments 7 and 8, it is often pointing towards the bare area of the liver. It is important to adequately mobilise the right lobe of the liver to allow access to this area (Fig. 15.6). The use of a snake retractor is useful in helping to mobilise the liver towards the left. Often both the falciform ligament and the right triangular liga­ment have to be divided to achieve this. This is a better way than to attempt to drain the abscess through a longer path via an entry point in the lower segment.
ii. Ruptured abscess
This is not a contraindication to laparoscopic
approach. Certainly, percutaneous drainage will not be adequate. The key issue is adequate lavage of the peritoneal cavity, including the inter-loop areas of the small bowel. An additional drain may be placed in the pelvis to reduce the chance of pelvic abscess.
iii. Concurrent pathology
Occasionally the causative pathology for the liver
abscess can be determined pre-operatively or dur­ing diagnostic laparoscopy. This may be addressed at the same time of the liver abscess drainage although additional ports may be placed to help in the dissection of the organs involved. Usually for an appendicectomy, an additional suprapubic port is placed while an additional right lateral port is placed for a cholecystectomy.
iv. Caudate lobe abscess
The drainage of a caudate lobe abscess is better
done laparoscopically than percutaneously as the
Figure 15.6.
Dividing the right triangular ligament to mobilise right lobe.
140 Atlas of Complicated Abdominal Emergencies
caudate lobe is “sandwiched” between the portal structures and the inferior vena cava, which may be at risk during percutaneous drainage. The lapa­roscopic approach will require opening the lesser omentum and lifting the left lobe towards the right. Occasionally the left triangular ligament may have to be divided before the left lobe can be lifted enough to expose the caudate lobe. More often with the caudate abscess, the lesser omen­tum lying on it becomes inflamed and adherent to the caudate lobe, but it can still be dissected from the caudate lobe. More often, an additional port may be necessary for the purpose of retraction.
v. Deep-seated abscess
In deep-seated abscesses in the right lobe of the
liver where there is more than 2 cm of paren­chyma tissue all around the abscess, it may be prudent to attempt drainage of the abscess percu­taneously rather than surgically. If this fails, the patient can then be brought into the operating room for surgical drainage using the percutaneous drainage catheter as a guide to reach the abscess.
In the occasional situation where there is an obvi­ous concurrent pathology that needs to be addressed in the first instance, the “percutaneous aspect” can be done intra-operatively under lapa­roscopic ultrasound guidance, and the surgical drainage can then be performed again using intra­operatively placed catheter (or guide wire) as a guide to reach the abscess cavity.

Final Note

As in all laparoscopic procedure, it is important that the surgeon is comfortable with the open approach in the event that the procedure has to be converted. This situation may arise when the patient cannot toler­ate peritoneal insufflation and develops haemody­namic instability. The surgical principle remains the same as described above except for a larger incision placed usually at the right subcostal. In such situations, it is therefore unlikely that a posterior transpleural approach can be undertaken.
Chapter 16
Interventional Radiology in the Management of Intra- Abdominal Abscess
Anil Gopinathan,* Quek Swee Tian† and Lenny Tan

Introduction

Intra- abdominal abscess, when leading to septic shock, has a mortality of over 50%. 1970s, surgical incision and drainage was the only practical way for achieving source control. Following the first report of percutaneous aspiration for abdomi­nal abscess by McFadzean in 1953, drainage of abdominal abscesses has had to wait another two decades for the advent of cross-sectional imaging techniques to enable universal acceptance as a less invasive alternative or complement to surgery.
1
Until the late
2
percutaneous
Advantages of Radiological
Drainage
1) It can avoid a major surgical undertaking without
precluding future surgery if indicated.
2) It permits multiple and repeated drain placements
with relatively little patient morbidity. This is a
major advantage as repeat laparotomies are often a nightmare for both the patient and the surgeon.
3) It allows precise drain placement into deep intra­abdominal locations that would otherwise warrant extensive organ mobilisation and tissue dissection to reach surgically, e.g. peripancreatic abscess.
4) It is almost always performed under local anaes­thesia which is rarely feasible for most surgical drainages.
5) Bedside drain insertion may be possible when amenable to ultrasound guided drainage.
6) Direct procedural complications are uncommon with radiological drainage.
7) It may be the best and only rational approach in certain select situations, e.g. percutaneous transhepatic biliary drainage (PTBD) in the treatment of post-biliary enterostomy strictures.
8) Radiological drainage may be possible in certain situations when surgical intervention is relatively contraindicated, e.g. high surgical risk patients, postoperative abscess following recent major surgery.
* Anil Gopinathan, MBBS, MD, DNB, FRCR (Lond), FAMS, Consultant Radiologist, Department of Diagnostic Imaging, National University Hospital, Singapore.
Quek Swee Tian, MBBS, FRCR, FAMS, Chief & Senior Consultant, Department of Diagnostic Imaging, National University Hospital,
Singapore.
Lenny Tan, MD, FSIR, Emeritus Consultant, Department of Diagnostic Imaging, National University Hospital, and Professor, National
University of Singapore, Singapore.
141