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19 Inferior Epigastric Artery Flap: Deep Inferior Epigastric Artery Perforator Flap
Fig. 19.17 Clinical illustration demonstrating drain placement, fascial closure, umbilicus retrieval and abdominal wall closure
197
(b) Rectus sheath catheters or TAP blocks can be used to
reduce systemic postoperative analgesic require­ments [12].
19.6 Core Surgical Techniques inFlap Dissection
19.6.1 Perforator Dissection
When in close proximity to the anticipated perforators, transi­tion to bipolar cautery. Meticulous dissection and haemostasis are essential at this stage as even a small amount of bleeding can cause tissue staining which renders the dissection much more difcult. With guidance from preoperative imaging, the dominant perforator is approached; however care should be taken to identify and preserve adjacent perforators which may be required in the event of smaller than anticipated dominant perforators. A suprafascial dissection is performed circumfer­entially around the dominant perforator and adjacent perfora­tors in the event of a small dominant perforator, before the fascia is incised. This creates a zone of safety around the per­forator and prevents future injury during the nal stages of ap raise. A small vascular clamp can be applied to the back-up perforator(s) to assess adequate perfusion and aid decision­making regarding the required number of perforators.
Bipolar cautery at low current of the planned fascial incision can reduce the risk of blood staining. Care must be taken when incising the fascia as the perforator can travel obliquely under the fascia before commencing its intramuscular course. When the fascia is rmly adherent to the perforator, it is safest to leave a small cuff of fascia around the vessel. The perforator must be circumferen­tially dissected in the subfascial plane as was performed suprafascially, and then intramuscular dissection can begin. The fascia is now incised parallel to the rectus abdominis bres. The muscle bres overlying the pedicle are gradually divided allowing adequate exposure of the entire pedicle length. Care is taken to identify and ligate or coagulate all side branches throughout the intramuscular course, a distance of 1–2mm from the main pedicle to pre­vent unintended vessel injury, thereby isolating the pedicle from the surrounding rectus muscle. The vessel runs in a loose areolar plane allowing blunt dissection and resis­tance is indicative of a side branch requiring ligation. The pedicle dissection proceeds until adequate length or ideal calibre vessel for anastomosis has been reached. Typically one artery and two venae comitantes are included in the pedicle. Ligation of the smaller vein at the end of the dis­sected pedicle diverts ow through the large vein prior to transfer and avoids confusion once the veins have col­lapsed post transfer.
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19.6.2 Nerve Preservation
Nerves enter the rectus with the lateral row perforators of the DIEA placing them at risk particularly when multiple lateral row perforators are harvested. When perforator dissection necessitates motor nerve division, we advocate a perineurial repair under loupe magnication with 9/0 nylon sutures once the ap has been harvested. Division of type II nerves results in larger segments of muscle denervation and potential for abdominal wall complications. Underlay mesh should be considered in this situation.
19.6.3 Bipedicled andStacked DIEP
Bipedicled and stacked DIEP aps are useful in women with a paucity of abdominal tissue, those requiring large volume reconstructions and those with midline abdominal scars. Bipedicled/stacked aps involve raising the entire abdominal pannus on two pedicles for a unilateral reconstruction. Murray etal. described a classication system for the use of the bipedicled ap, the pedicle options and the four types of intraap anastomotic congurations [13]. The internal mam­mary artery/vein (IMA/V) antegrade or large intercostal per­forator remains the primary recipient; however in type 4 anastomosis, where pedicles are independently anastomosed, the IMA/V retrograde is also used. Shaping the entire abdominal ap has been described in four different congu­rations involving folding, dividing and coning the tissue to achieve best aesthetic outcomes [14].
19.7 Breast Neurotisation
Post-mastectomy breast numbness has a signicant impact on postoperative quality of life with patients now seeking not only reconstruction of the breast mound but also restoration of cutaneous sensation. The value of nerve coaptation has been debated in the literature with some arguing collateral ingrowth from surrounding nerve bres is sufcient for pro­tective sensation; however a recent study of bilateral autolo-
gous breast reconstruction with unilateral sensory nerve coaptation demonstrates improved sensory recovery in the neurotised breast compared to the contralateral non­neurotised breast [15, 16].
19.8 Clinical Scenario
Case 1: Immediate Unilateral Breast Reconstruction
A 56-year-old female underwent unilateral skin sparring, nipple sacricing mastectomy and sentinel lymph node biopsy for a grade 2 invasive ductal carcinoma of the left breast. Mastectomy weight was 914g. She underwent imme­diate reconstruction with stacked DIEP aps with a total ap weight of 1029g (Fig.19.18a, b).
Case 2: Bilateral Delayed Reconstruction
A 58-year-old lady underwent bilateral breast reconstruc­tion with DIEP free aps 4years post bilateral mastectomy and left sentinel lymph node biopsy (SLNB) for left breast grade III IDC and high-grade DCIS; concurrent SLNB was negative for malignancy. Mastectomy weights were right 700 g and left 990 g and DIEP reconstructions weighed 676g and 862 g. Post-op day 1 the ap was noted to be venously congested, and she underwent return to theatre for a cephalic turn-up and anastomosis to the SIEV with a suc­cessful outcome (Fig. 19.19). (See Video 19.1—demon­strating another case of a delayed DIEP with cephalic turndown.)
Case 3: Bilateral Immediate Reconstruction with Mastectomy Skin Reduction for Ptosis Correction
A 44-year-old lady underwent a bilateral nipple-sacricing mastectomy for strong family history and BRCA1 genetic mutation with immediate breast reconstruction with DIEP free ap. Mastectomy weights were right 531 g and left 676g, and her respective ap reconstructions weighed 484g and 525g. She was noted to have grade III ptosis and was subsequently planned for bilateral skin reduction with an inverted T technique to be performed simultaneously (Fig.19.20a, b).
19 Inferior Epigastric Artery Flap: Deep Inferior Epigastric Artery Perforator Flap
a
199
b
Fig. 19.18 (a) A 56-year-old lady underwent a unilateral immediate breast reconstruction with stacked DIEP ap. Preoperative photographs. (b) Post reconstruction
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a cb
A. O’Neill et al.
Fig. 19.19 (a) Case 2: Preoperative markings of a 58-year-old lady undergoing delayed breast reconstruction 4 years following bilateral mastectomy. Note the template of the new breast footprint, with care taken to prevent symmastia of the reconstructed breasts. (b) On table
a b
appearances immediately following bilateral delayed breast reconstruc­tion with DIEP free aps. (c) 12 months following bilateral delayed breast reconstruction with DIEP aps, very faint scars from the cephalic turn-up procedure can be seen
Fig. 19.20 (a) Case 3: Preoperative markings for a 44-year-old woman undergoing bilateral breast reconstruction, requiring simultaneous reduc- tion of the skin envelope. (b) Day 2 post-bilateral breast reconstruction with wise pattern skin reduction
19 Inferior Epigastric Artery Flap: Deep Inferior Epigastric Artery Perforator Flap
19.9 Pearls andPitfalls
Nerve preservation
Motor nerve preservation is essential for preserving
function of the rectus abdominis muscle but should not
Patient selection is key to success. Patient understanding of expected volume, abdominal scarring that is typically higher than a cosmetic abdomi­noplasty and the transfer of abdominal wall features such as striae, moles, etc. is key to patient satisfaction. Numerous studies demonstrate increased complica­tions in both active and ex-smokers, and patients should be counselled to cease smoking 6weeks either side of surgery [17]. Although signicant interunit variability exists, extrapolated evidence suggests a BMI over 30 is associated with increased morbidity, predominantly donor site morbidity. Reconstruction is generally afforded to women with a BMI up to 32; however, immediate cases can be considered judi­ciously up to a BMI of 35 [18]. Dual consultant team has been shown to reduce sur­gical time and also provides an ideal opportunity for training and mentorship of junior surgeons [19, 20]. In delayed breast reconstruction, one team can prepare the breast pocket and recipient vessels, while the sec­ond team raises the DIEP ap from the contralateral abdominal wall. In bilateral breast reconstruction, while one team is performing the microvascular anas­tomoses, the second team can proceed with the second DIEP ap raise.
Adjustment of ap markings
The inferior and superior ap incisions can be moved superiorly to increase tissue capture and ensure tension- free closure of the abdominal wound.
Perforator selection
Preoperative CT angiogram provides an excellent guide to perforator selection. If the perforator is small, then a second perforator should be included in the ap. If there is uncertainty about the perfused skin territory, adjacent perforators can be preserved and vascular clamps applied to assess the ap perfusion. If deemed adequate, then the perforators can be ligated with hae­moclips. Similarly, in unilateral DIEPs the contralat­eral DIEA perforators can be dissected suprafascially and microvascular clamps applied on the dominant perforators as a contingency plan.
Venous lifeboat
Time should be taken to preserve a 3–5cm length of the supercial epigastric vein which can provide a sec­ondary venous outow in the event of venous conges­tion. The SIEV can be dissected into the ap in the event it is required.
compromise ap perfusion. If a second perforator is
required at the cost of a nerve, then the perforator takes
precedence, and mesh should be considered to aug-
ment the rectus abdominis.
Flap preparation on the abdomen
Mark and excise zone IV plus any obvious ap excess
so that the ap is marginally bigger than anticipated.
Judicious de-epithelialisation can occur prior to trans-
fer. Delayed reconstructions can be more difcult in
predicting the extent of de-epithelialisation and are
often easiest if done during ap inset.
Abdominal closure
Elevation of the superior abdominal skin early in the
operation facilitates abdominal wall closure during the
ap inset.
Identify abdominal scars
Pfannenstiel incisions don’t preclude the use of the
DIEP ap, consideration should be made regarding
incorporating the scar in the inferior incision versus
placing the ap incision a safe distance from the scar,
and the surgeon should be aware of the increased scar-
ring in this region.
Flap inset—immediate versus delayed breast recon-
struction—ap orientations (Fig.19.21).
Delayed breast reconstruction requires recreation of
the breast footprint and reestablishment of the infra-
mammary fold (IMF). In cases of unilateral delayed
reconstruction, the contralateral breast can be used to
guide IMF placement, typically 2 to 3cm higher than
the contralateral side unless there is signicant skin
brosis and contraction at the mastectomy site, in
which case the IMF should be positioned higher. The
scar is excised, and the skin between the scar and IMF
is de-epithelialised which aids creation of lower pole
projection. The breast pocket above the scar is raised
according to the preoperative footprint markings supe-
riorly, medially and laterally. The ap then needs to be
fashioned into a three-dimensional asymmetric conus
to replicate the native breast. Although not essential,
we routinely utilise the contralateral abdomen which is
rotated 180 degrees as originally recommended by
Blondeel which places the bulk of the ap in the infe-
rior pole of the breast. Once the anastomoses are per-
formed, shaping of the breast begins. Techniques such
as removing a wedge of tissue from the periumbilical
region to create greater inferior fullness and suture
techniques are described for creating the breast conus.
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Fig. 19.21 Preoperative marking and postoperative skin paddle differences between immediate and delayed unilateral breast reconstructions
We recommend making the reconstructed breast 10% larger than the native breast to account for resolution of swelling postoperatively and to create an appropri­ate scaffold that can be liposculpted during a future procedure. In immediate reconstructions, the ap weight is guided by the mastectomy weight. In particularly ptotic breasts or where the patient requests a breast reduction at the time of reconstruction, the excess skin envelope can be addressed with a keyhole or wise pattern skin reduction. It is essential to mark the breast footprint preoperatively and reconstruct any borders that are violated during the mastectomy, the most common being the IMF and the lateral border. Sutures are again used to fashion the breast conus, with the skin gently draped over the ap and the nal result assessed.
19.10 Selected Readings
203
reading for all surgeons reconstructing the breast as it
simplies a complex reconstructive problem into three key
anatomic features, thereby providing an algorithm of
sorts to produce consistent and aesthetically pleasing
reconstructive results.
• Blondeel PN, etal. Shaping the breast in aesthetic and
reconstructive breast surgery: an easy three-step princi-
ple. Part II--Breast reconstruction after total mastectomy.
Plast Reconstr Surg. 2009;123(3):794–805 [23].
Part two of the four-part series builds on the anatomic
features discussed in part one and provides an approach
to analysing the post-mastectomy breast. It explores dif-
ferences in unilateral and bilateral breast reconstruction
as well as primary versus delayed reconstruction provid-
ing key steps to addressing the breast footprint, conus and
skin envelope. This is a must-read paper for any surgeon
embarking on a career in breast reconstruction.
• Hembd AS, etal. Intraoperative assessment of DIEP ap
breast reconstruction using indocyanine green angiogra-
phy: reduction of fat necrosis, resection volumes, and
postoperative surveillance. Plast Reconstr Surg.
2020;146(1):1e–10e.
• Koshima I, Soeda S.Inferior epigastric artery skin aps without rectus abdominis muscle. Br J Plast Surg. 1989;42(6):645–8.
The original paper demonstrating a large fasciocutane-
ous ap based on a single rectus abdominis muscle perfo­rator was possible, thereby addressing the donor site morbidity associated with rectus abdominis sacrice and the bulk issues that were sometimes undesired with the TRAM ap.
• Dancey A, Blondeel PN.Technical tips for safe perforator vessel dissection applicable to all perforator aps. Clin Plast Surg. 2010;37(4):593–606, xi–vi [21].
A comprehensive stepwise approach to DIEA perforator
dissection accompanied by detailed intraoperative pho­tography and numerous technical tips learned throughout the senior authors’ extensive career.
• Rozen WM, etal. The perforator angiosome: a new con­cept in the design of deep inferior epigastric artery perfo­rator aps for breast reconstruction. Microsurgery. 2010;30(1):1–7.
This paper identies fundamental differences in the
medial and lateral row perforators of the DIEA and pro­poses a new model of abdominal wall perfusion based on a single perforator.
• Blondeel PN, etal. Shaping the breast in aesthetic and reconstructive breast surgery: an easy three-step princi­ple. Plast Reconstr Surg. 2009;123(2):455–62 [22].
The rst of a four-part series addressing the aesthetics of
breast reconstruction. While not directly related to micro­vascular breast reconstruction, this paper is essential
Acknowledgements We thank Julia Ruston for her illustrations in this chapter for the text and also the video.
References
1. Koshima I, Soeda S. Inferior epigastric artery skin aps without rectus abdominis muscle. Br J Plast Surg. 1989;42(6):645–8.
2. Allen RJ, Treece P. Deep inferior epigastric perforator ap for breast reconstruction. Ann Plast Surg. 1994;32(1):32–8.
3. Moon HK, Taylor GI.The vascular anatomy of rectus abdominis musculocutaneous aps based on the deep superior epigastric sys­tem. Plast Reconstr Surg. 1988;82(5):815–32.
4. Blondeel PN, etal. Doppler owmetry in the planning of perforator aps. Br J Plast Surg. 1998;51(3):202–9.
5. Bailey SH, etal. The single dominant medial row perforator DIEP ap in breast reconstruction: three-dimensional perforasome and clinical results. Plast Reconstr Surg. 2010;126(3):739–51.
6. Schaverien M, etal. Arterial and venous anatomies of the deep infe­rior epigastric perforator and supercial inferior epigastric artery aps. Plast Reconstr Surg. 2008;121(6):1909–19.
7. Rozen WM, etal. The perforator angiosome: a new concept in the design of deep inferior epigastric artery perforator aps for breast reconstruction. Microsurgery. 2010;30(1):1–7.
8. Rozen WM, et al. Avoiding denervation of rectus abdominis in DIEP ap harvest: the importance of medial row perforators. Plast Reconstr Surg. 2008;122(3):710–6.
9. Masia J, etal. Multidetector-row computed tomography in the plan­ning of abdominal perforator aps. J Plast Reconstr Aesthet Surg. 2006;59(6):594–9.
10. Hembd AS, et al. Intraoperative assessment of DIEP ap breast reconstruction using indocyanine green angiography: reduction of fat necrosis, resection volumes, and postoperative surveillance. Plast Reconstr Surg. 2020;146(1):1e–10e.
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11. Momeni A, Sheckter C.Intraoperative laser-assisted indocyanine green imaging can reduce the rate of fat necrosis in microsurgical breast reconstruction. Plast Reconstr Surg. 2020;145(3):507e–13e.
12. Zhong T, et al. Transversus abdominis plane (TAP) catheters inserted under direct vision in the donor site following free DIEP and MS-TRAM breast reconstruction: a prospective cohort study of 45 patients. J Plast Reconstr Aesthet Surg. 2013;66(3):329–36.
13. Murray A, etal. Stacked abdominal ap for unilateral breast recon­struction. J Reconstr Microsurg. 2015;31(3):179–86.
14. Patel NG, et al. Stacked and bipedicled abdominal free aps for breast reconstruction: considerations for shaping. Gland Surg. 2016;5(2):115–21.
15. Slezak S, McGibbon B, Dellon AL. The sensational transverse rectus abdominis musculocutaneous (TRAM) ap: return of sensibility after TRAM breast reconstruction. Ann Plast Surg. 1992;28(3):210–7.
16. Bijkerk E, et al. Breast sensibility in bilateral autologous breast reconstruction with unilateral sensory nerve coaptation. Breast Cancer Res Treat. 2020;181(3):599–610.
17. Klasson S, et al. Smoking increases donor site complications in breast reconstruction with DIEP ap. J Plast Surg Hand Surg. 2016;50(6):331–5.
18. Lee KT, Mun GH.Effects of obesity on postoperative complica­tions after breast reconstruction using free muscle-sparing trans­verse rectus abdominis myocutaneous, deep inferior epigastric perforator, and supercial inferior epigastric artery ap: a system­atic review and meta-analysis. Ann Plast Surg. 2016;76(5):576–84.
19. Butler DP, Woollard A, Grobbelaar AO. Dual-consultant led elec­tive microsurgery: the implications on service provision and train­ing. J Plast Reconstr Aesthet Surg. 2013;66(10):1435–6.
20. Canizares O, et al. Optimizing efciency in deep inferior epi­gastric perforator ap breast reconstruction. Ann Plast Surg. 2015;75(2):186–92.
21. Dancey A, Blondeel PN. Technical tips for safe perforator ves­sel dissection applicable to all perforator aps. Clin Plast Surg. 2010;37(4):593–606, xi–vi.
22. Blondeel PN, etal. Shaping the breast in aesthetic and reconstruc­tive breast surgery: an easy three-step principle. Plast Reconstr Surg. 2009;123(2):455–62.
23. Blondeel PN, et al. Shaping the breast in aesthetic and recon­structive breast surgery: an easy three-step principle. Part II-­Breast reconstruction after total mastectomy. Plast Reconstr Surg. 2009;123(3):794–805.
Inferior andSuperior Epigastric Artery Flaps: TheRectus Abdominis Muscle Flap
MatthewWordsworth, DariushNikkhah, AlexWoollard, andNorbertKang
20
20.1 Introduction
The deep inferior epigastric artery is a workhorse of recon­structive plastic surgery. It can be raised as a muscle ap or as a myofasciocutaneous ap with a wide range of skin pad­dles; the inferior epigastric artery supplies the largest skin area on the body. It is most commonly used as a fasciocuta­neous ap in breast reconstruction (the DIEP ap) or as a transverse rectus abdominis myofasciocutaneous ap (the TRAM ap). As an inferiorly based pedicled ap, the tissue pivots at the level of the pubis, and the ap is used for peri­neal, groin and lower trunk reconstruction, usually with a vertically orientated skin paddle (the VRAM ap). The rec­tus abdominis muscle can also be raised on the superior epi­gastric artery, as a pedicled ap to reconstruct chest wall and midline sternal defects.
In the 1970s a number of surgeons had published on using a superiorly based pedicled rectus muscle ap for breast and chest wall reconstruction, but the rst use of the inferior epi­gastric artery free rectus muscle ap was by published by Pennington etal. [1]. The work of Taylor etal. [2] demon­strated the dense anastomotic network between the super­cial and deep inferior epigastric vessels and reliability of the skin perforators. The rectus abdominis ap has been described in both limb and head and neck reconstruction, but it is most commonly used when the abdomen has been opened as part of the resection surgery. Pedicled VRAMs in
M. Wordsworth (*) Royal Centre for Defence Medicine, Birmingham, UK e-mail: matt.wordsworth1@nhs.net
D. Nikkhah · A. Woollard · N. Kang Royal Free Hospital, London, UK e-mail: d.nikkhah@nhs.net
perineal reconstruction have been shown to reduce wound healing complications in irradiated abdominoperineal resec­tion defects [3].
20.2 Anatomy
The rectus abdominis muscle can be easily palpated and visualised in slim patients. The medial border is the midline, the linea alba, and the lateral border is the linea semilunaris. The rectus abdominis muscle is 7–10cm wide and is a long muscle stretching from its origin at the cartilaginous union of the lower ribs and xiphisternum to the insertion at the sym­physis and crest of the pubis bone. The muscle is segmented by three (rarely four) tendinous insertions running horizon­tally creating the colloquially named ‘six-pack’ appearance. Anterior to the rectus muscle throughout its length is the anterior rectus sheath consisting of the aponeurosis of the external oblique muscle and the anterior aponeurosis of the internal oblique muscle. The posterior rectus sheath consists of the posterior aponeurosis of the internal oblique and the aponeurosis of the transversus abdominis muscle until that sheath ends at the horizontal level of the anterior superior iliac spine: the arcuate line. Caudal to the arcuate line, the rectus muscle therefore only lies on the transversalis fascia and parietal peritoneum (Fig. 20.1). The rectus abdominis muscle is innervated segmentally by terminal branches of the intercostal nerves from the sixth to twelfth ribs; these nerves enter the muscle posteriorly on the lateral third of the muscle.
The rectus abdominis ap has a Mathes and Nahai type III arterial supply with two dominant and minor pedicles. The dominant pedicles are the superior and inferior epigastric arteries. The internal mammary artery and vein become the superior epigastric vessels and insert into the superior third of the rectus muscle posteriorly and medially. The superior epigastric vessels anastomose in the middle third of the mus­cle with the inferior epigastric artery and vein, a branch of
© Springer Nature Switzerland AG 2023 D. Nikkhah et al. (eds.), Core Techniques in Flap Reconstructive Microsurgery, https://doi.org/10.1007/978-3-031-07678-7_20
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Fig. 20.1 Rectus sheath anatomy
M. Wordsworth et al.
Above the
arcuate line
Peritoneum
Transversalis fascia
Below the
arcuate line
Peritoneum
Transversalis fascia
the external iliac artery and vein. The inferior epigastric artery pierces the transversalis fascia and enters the muscle at the inferior aspect of the middle third, posteriorly and in the lateral aspect of the muscle. The minor pedicles are six small intercostal arteries and one subcostal artery that enter the deep aspect of the muscle and anastomose with the epi­gastric arteries. Anatomical variability exists with the number of anastomoses between the superior and inferior epigastrics and where the deep inferior epigastric vessels enter the mus­cle (usually 3cm caudally to the arcuate line)—see Moon and Taylor [4] for more detail. The inferior epigastric artery is typically 2–4mm diameter and 5–10 cm pedicle length can be harvested. Venous drainage is from two venae comi­tantes with one vein usually similar in size to the artery.
External oblique
muscle
Linea alba
Linea alba
Internal oblique m.
Transversus abdominus m
External oblique
muscle
Internal oblique m.
Transversus abdominus m
20.4 Flap Design andMarkings
The design of the rectus abdominis ap depends on which components are required. The ap can be raised as a muscle­only ap but it is more commonly used with a skin paddle. The skin paddle can be orientated vertically, horizontally or obliquely. The para-umbilical perforators are the most crucial for skin perfusion, and therefore the fasciocutaneous portion of the ap should not be dissected from the central portion of the rectus muscle belly. An extended VRAM that incorporates a vertical skin paddle with an oblique extension to the costal margin has been described by Villa etal. [5]. The size of the skin paddle is determined by the requirements of the defect and what can be closed directly in the donor site.
20.3 Preoperative Investigation
Skin perforators in the rectus abdominis ap can be simply identied using handheld Doppler. CT angiography is not mandated but is recommended in instances where previous surgery may have affected the normal vascular anatomy of the inferior and superior epigastric arteries. Preoperative CT
20.5 Flap Raise/Elevation
In this description a pedicled myocutaneous ap is used with a vertical skin paddle over the middle and upper portion of the rectus for a perineal reconstruction after an open abdomi­noperineal resection, for example, for the excision of a low rectal carcinoma.
angiography reduces the duration of surgery in DIEP breast reconstruction, and this may be applicable when mobilising the inferior epigastric artery in the setting of a rectus abdom­inis ap.
Step 1: Skin Marking Choose the side, contralateral to any planned or current stoma or signicant scars. Mark the mid­line, and curve around the umbilicus so that it is not incorpo-