Добавил:
kiopkiopkiop18@yandex.ru t.me/Prokururor I Вовсе не секретарь, но почту проверяю Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:

Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_4372_Библиотеки_им_академика_М_И_Перельмана

.pdf
Скачиваний:
0
Добавлен:
29.08.2026
Размер:
94 Мб
Скачать
17 Total Conservative andRadical Parotidectomy
https://t.me/med1917
171
Table 17.1 European Salivary Gland Society (ESGS) classication: nonparotid structures that may need removal
Symbol Denition
CN VII Facial nerve trunk and/or all the main
branches
CN VII t-z-b-m-c Facial nerve branchesa: temporal, zygomatic,
buccal, marginal mandibular, cervical ECA External carotid artery GAN Greater auricular nerve LTB Lateral temporal bone MB Mastoid bone MM Masseter muscle S Skin TMJ Temporomandibular joint PPS Parapharyngeal space
ESGS classication: Comparison with classic descriptions ESGS classication Classic classication
Parotidectomy I–IV (VII) Parotidectomy I–IV Total parotidectomy with facial nerve
Parotidectomy I–IV (VII, S, MM)
a
When all the nerves have been sacriced, just use “CN VII,” but when the surgeon has sacriced just some branches, then “CN VII z,” for example, means the surgeon has removed only the zygomatic branches
Total parotidectomy with facial nerve resection
preservation Extended total parotidectomy with facial nerve resection plus skin and masseter muscle resection
a
In certain circumstances, small, isolated malignant tumours of the parotid gland can also be managed with par­tial parotidectomy preserving the facial nerve branches. Wide surgical margins are not possible with facial nerve– preserving parotid surgery, as these tumours are almost always intimately associated with one or more branches of the facial nerve. “Wide surgical” resection would involve sacrice of one or more of these nerves. A signicant propor­tion of patients with malignant parotid tumours will also receive adjuvant radiotherapy, questioning the additional benet of more radical parotid surgery.
17.2.2 Indications forTotal Conservative
Parotidectomy
Total conservative parotidectomy (TCP) is much less com­monly performed and is limited to certain circumstances. TCP may be considered as a last resort for situations such as chronic sialadenitis and rst bite syndrome following para­pharyngeal space surgery, but it is rarely required, because other effective treatment modalities such as Botox are available.
a b
Fig. 17.2 The European Salivary Gland Society (ESGS) division in ve levels. A case of supercial parotidectomy showing the four levels. The separation between superior and inferior levels is established with an imaginary line connecting the bifurcation of the facial nerve main
trunk (F) in its two major branches (temporofacial and cervicofacial) with Stensen’s duct (St). Five ESGS levels: I (lateral superior), II (lat­eral inferior), III (deep inferior, under CN VII), IV (deep superior, under CN VII), V (accessory)
172
https://t.me/med1917
V. VanderPoorten and M. Elliott
17.2.2.1 TCP forBenign Tumours
TCP is indicated for multifocal recurrent pleomorphic ade­noma, as an ultimate attempt to remove all parotid tissues encompassing what may be many tiny foci of pleomorphic adenoma. TCP is also performed when removing a superi­orly located deep-lobe parotid tumour (ESGS level IV, high tumours abutting the facial nerve from beneath), when the facial nerve is stretched over the tumour. CN VII thus must be identied rst, dissected, and released off the deep-lobe tumour so as to facilitate the tumour’s safe removal whilst preserving the nerve’s integrity.
17.2.2.2 TCP forMalignant Tumours
If the facial nerve is functioning normally before surgery, the aim should be to preserve the nerve [6]. Even for high-grade parotid cancers, long-term local control can be obtained with facial nerve preservation if only microscopic residual disease is left and is treated with postoperative radiotherapy [5, 8, 9]. It is also important to keep in mind that, theoretically, in many situations, “The tumour can be radically removed from the nerve (by cutting it), but not from the patient.” This means that one should not aim for a wide margin at the level of CN VII if close margins are expected at other levels in the surgical eld.
TCP is required in several situations [6, 10]:
• Intraparotid metastatic lymph nodes
• Malignant tumours of the deep lobe
• A large, grossly inltrative malignant tumour with extra­parenchymal extension in surrounding structures such as the masseter muscle, mastoid bone, lateral temporal bone, or temporomandibular joint
• Parotid tumours with extensive neck nodal metastasis
Performing a total parotidectomy also has strong propo-
nents when dealing with skin cancer metastasis to the parotid, although no prospective data support this approach. O’Brien etal. [11] observed a 20% local recurrence rate (two-thirds in the deep parotid lobe bed) in 87 skin cancer patients with clinical parotid metastasis, most of whom had been treated with a supercial parotidectomy (82%) and despite adjuvant radiation (86%). It is unclear whether leaving tissue deep to CN VII was the origin of recurrence, but the authors made a case for performing total parotidectomy in these instances. This approach is supported by Olsen et al. [12, 13]. Total parotidectomy for metastatic squamous cell carcinoma in their patients resulted in parotid control rates of 93% at a median follow-up of 36.4months.
As with partial parotidectomy, TCP remains an area of
discussion for malignant parotid tumours in the supercial lobe, with low T classication and pre-operatively known high grade [5, 6, 10]. Many authors would say that a super­cial parotidectomy is sufcient, relying on postoperative
radiotherapy to control potential microscopic disease and/or involved deep-lobe parotid lymph nodes [1419]. Some authors stay in the middle and suggest that one should “inspect and resect the deep lobe if there is suspicion of deep lobe nodal metastasis” [5]. Other authors suggest proceeding with TCP in these specic situations, observing a high rate of intraparotid lymph node metastasis in resected deep parotid lobes [13, 2022]. This area of controversy would certainly benet from additional prospective research.
17.2.3 Indications forRadical Parotidectomy, ESGS I–V (VII)
In the setting of preoperative facial nerve paresis or palsy, resection of the nerve is indicated, with the extent of resection guided by the abnormality of the facial nerve on MRI scan and/or intraoperative frozen section. The facial nerve can be chased proximally into the temporal bone, as indicated by frozen section. One can also encounter intraoperative nerve entrapment with carcinoma in the setting of a functioning nerve; this situation requires facial nerve sacrice for onco­logical resection.
An absolute indication for CN VII resection is preopera­tive nerve dysfunction, with the exception of the preopera­tive or perioperative (frozen section) diagnosis of parotid lymphoma. Relative indications include imaging studies (MRI) showing gross inltrative malignant disease on the course of CN VII (Fig.17.3). In this circumstance, the patient is counselled preoperatively about the potential for facial nerve sacrice and reconstruction using static or dynamic reanimation.
Depending on preoperative imaging and perioperative ndings, the radical parotidectomy can be extended to involve resection of adjacent nonparotid structures involved
Fig. 17.3 MRI showing gross inltrative malignant disease on the course of the right CN VII (arrow). In this circumstance, the patient is counselled preoperatively about the potential for facial nerve sacrice and reconstruction using static or dynamic reanimation
17 Total Conservative andRadical Parotidectomy
https://t.me/med1917
173
with cancer, such as all those listed on Table17.1, and can involve an appropriate neck dissection based on nodal meta­static disease [6, 10].
17.3 Surgical Technique
17.3.1 Facial Nerve Monitoring
The use of facial nerve monitoring is controversial and is based on the surgeon’s individual preference and on individ­ual surgical situations. Guntinas-Lichius and Eisele [23] conclude, in their recent review, that facial nerve monitoring is reasonable in all instances where facial nerve identica­tion, dissection, and preservation are potentially difcult; surgery for malignant and difcult benign tumours is included in their list. Makeieff etal. [24] found in their study on recurrent pleomorphic adenoma that both the rate of facial nerve palsy and the duration of the procedure were signi­cantly reduced when using CN VII monitoring. Sood etal. [25] performed a meta-analysis and concluded that “the number needed to treat” was nine, so in order to prevent one immediate postoperative CN VII dysfunction, nine patients needed to be monitored. Facial nerve monitoring should be considered for revision surgical cases, patients with prior radiotherapy, patients with extensive tumours, and patients in whom radical parotidectomy is being performed and iden­tication of distal facial nerve branches is required for reconstruction.
17.3.2 Incision Planning andExecution
A number of incisions have been described, including a Blair, modied Blair, and facelift incision. A modied Blair or lazy S incision, with or without a retrotragal part at the upper part of the incision, is usually preferable over a facelift incision, for it provides better access with less dissection and is more readily prolonged into an extension for a neck dis­section. Planning of the skin incision also must take into account potential resection of overlying skin if it is involved in cancer.
The skin ap dissection is preferably done in the sub­SMAS plane if the tumour does not extend that far super­cially. The greater auricular nerve (GAN) is identied in the neck and traced superiorly, with preservation of the posterior branches of the GAN if possible to minimize postoperative facial numbness. The GAN can also be used for cable graft­ing if required [26].
The parotid gland is dissected off the tragal perichon­drium and off the sternocleidomastoid muscle (SCM) . The facial nerve trunk is identied using the most reliable land­mark (the tympanomastoid suture) and at the level of the
posterior belly of the digastric. Alternative landmarks such as the tragal pointer can be used. A retrograde dissection is sometimes required for tumours arising around the stylomas­toid foramen.
17.3.3 Total Conservative Parotidectomy
Whether the tumour is located supercially or deep to CN VII, the rst step is to perform a complete supercial paroti­dectomy, as described in Chap. 19 (Fig.17.4). An elegant technique of subsequently performing an en bloc deep-lobe parotidectomy with facial nerve preservation has been described by Olsen and Moore [12]. First, CN VII is sepa­rated from the deep lobe with meticulous microdissection. Operating loupes and micro-instruments (such as used in microvascular reconstruction) greatly aid in this step. There uniformly is a branch of CN VII passing into the deep lobe (the connecting branch to the auriculotemporal nerve, at the posterior border of the masseter muscle [MM]) [27]. This branch is divided without effect on the motor function (Fig.17.5). Anteriorly, the deep parotid lobe is then mobi­lized off the MM (Fig.17.6). On its inferior aspect, the deep lobe is mobilized from the stylohyoid, stylopharyngeus, and posterior digastric muscles. Essential for a controlled en bloc deep lobe removal is division and ligation of the externa carotid artery and the retrofacial vein inferiorly (Fig.17.7) and the supercial temporal artery and the vein superiorly. Then the deep parotid lobe can be mobilized downward, off the temporomandibular joint (Fig. 17.8). The nal step is elevation of the deep lobe off the posterior border of the mandible. Following division and ligation of the internal maxillary veins and artery, the deep lobe is then released from underneath the CN VII branches (Fig.17.9).
In some instances, part of the facial nerve (such as the buccal branch) must be sacriced. It goes without saying that cable grafting of a more distally located part of the CN VII has a more favourable outcome than when a complete defect from the main trunk to the different peripheral branches has to be bridged, losing the topographic innervation of the facial muscles, as outlined in the next paragraph.
17.3.4 Total Radical Parotidectomy; Extended
Radical Parotidectomy
In contrast to a TCP, a radical parotidectomy is more straightforward as meticulous dissection of the facial nerve branches is not required. As with TCP, where possible, the facial nerve trunk is identied at the stylomastoid foramen. The facial nerve trunk is divided, and a stump is left for facial nerve grafting. The distal branches are identied and tagged for later facial nerve grafting. (A nerve monitor
174
a
without effect on the motor function
retromandibular
https://t.me/med1917
V. VanderPoorten and M. Elliott
b
c
Fig. 17.4 Malignant parotid tumour with skin invasion requiring a conservative total parotidectomy with skin resection (parotidectomy I– IV (S)) and modied radical neck dissection. (a) Elevation of skin aps with involved skin attached to the specimen. (b) The situation after
Masseter
Muscle (MM)
Cut
vein
Connecting branch to the auriculotemporal
nerve at the posterior border of the
Masseter Muscle (MM) is divided
Fig. 17.5 CN VII branches are gently microdissected off the underly­ing deep-lobe parotid parenchyma. The connecting branch to the auric­ulotemporal nerve, at the posterior border of the masseter muscle (MM), is divided without effect on the motor function
supercial parotidectomy (ESGS I–II) and neck dissection in progress and after completion (c) of neck dissection before starting deep lobe parotidectomy (ESGS III–IV)
greatly assists with this identication.) The resection is car­ried out as for a TCP.
If there is cancer involving structures beyond the parotid gland, an extended radical parotidectomy is performed, removing the involved structure(s). For cancers involving the ear canal or facial nerve in the temporal bone, a lateral tem­poral bone resection is performed. Extended radical paroti­dectomy is often accompanied by a neck dissection (Fig.17.10). Reconstruction is carried out at the same opera­tion and includes procedures relating to static and dynamic facial nerve reanimation, as well as reconstruction of soft tis­sue and/or skin defects.
17.3.5 Wound Closure withor Without
Reconstruction
Ideally, the surgeon will start the resection with a good recon­structive plan, so that obtaining free margins is not compro­mised by lack of reconstructive possibilities, and sacricing donor nerves (such as the GAN) and essential donor and accep-
Stylohyoid muscle
17 Total Conservative andRadical Parotidectomy
https://t.me/med1917
175
a
b
Fig. 17.6 Anteriorly, the deep parotid lobe is then mobilized off the MM. (a) Schematic. (b) Real-life situation
tor blood vessels is avoided. When supporting tissues such as the MM must be resected (resulting in denuded mandibular bone), the parapharyngeal space (PPS) or infratemporal fossa tissues or lateral temporal bone composite aps are required to restore the defect [28]. One can consider using pedicled aps (pectoralis major myocutaneous and pedicled latissimus dorsi ap), especially in the unt patient, in failed free-ap recon­structions, or in combination with free-ap reconstructions, but generally, microvascular free aps are preferred. The anterolat­eral thigh (ALT) perforator ap can be adapted to the needs and thus is very popular in this area. It can be dissected suprafas­cially as a thin cutaneous ap; alternatively, vastus lateralis or rectus femoris muscle can be included, so that it becomes a musculocutaneous ap. It combines a relatively constant anat­omy, a possible two-team approach (the donor site being at a distance from the ablative eld), and a long (8–16cm) and large-calibre (2–2.5 mm) pedicle. When mainly volume is needed, a de- epithelialized ALT ap combined with a cervico­facial rotation ap can give a superior esthetic result.
When a parotid tumour invades the mandible, the resec­tion will typically result in a lateral mandibular defect with or without the condyle. For the sake of simplicity, this defect can be restored with soft tissue reconstruction only (ALT, latissimus dorsi, rectus abdominis), providing acceptable speech, mastication, and frontal facial symmetry at rest, but it entails malocclusion and deviation to the resected side on mouth opening. Osseous reconstruction generally works well only when the temporomandibular joint can be pre-
Fig. 17.7 Division and ligation of the external carotid artery and retromandibular vein inferiorly
Stylopharyngeus
muscle
Ligated & cut
external carotid
artery
Ligated & cut
retromandibular
vein
176
temporal artery and
https://t.me/med1917
Fig. 17.8 Division and ligation of the supercial temporal artery and the vein superiorly. Then the deep parotid lobe can be mobilized downward, off the temporomandibular joint
V. VanderPoorten and M. Elliott
Divided superficial
vein
Deep veins
a c
Fig. 17.9 The nal step is division and ligation of the internal maxillary veins and artery (a and b). The deep lobe is then released from underneath the CN VII branches (c)
b

abc
17 Total Conservative andRadical Parotidectomy
https://t.me/med1917
Fig. 17.10 Clinical (a) and PET-CT images (b) indicate the need for a parotidectomy ESGS I–IV (VII, GAN, MM, lateral temporal bone, external carotid artery). To the right (c), the resulting postablative situation can be observed
177
served. Then, an osteocutaneous bula ap can restore bone and skin defects. If additional soft tissue is needed, one can include the soleus muscle [6].
skin (and subcutaneous soft tissue) to be harvested without having to perform microvascular anastomosis. This ap can also be used as a de-epithelialized “ller” ap [32].
Following resection of CN VII, the reconstructive goal is to allow for facial expression of emotions whilst safeguard­ing vision, nasal airow, and oral competence. This aim is
17.4 Conclusion
best reached by immediate cable grafting, with static measures for the eyelid, nasolabial groove, and the angle of the mouth, which help bridge the period until facial muscu­lature reinnervation is achieved [28]. The best donor nerve for cable grafting is the GAN: It lies in the operative eld, so there is easy access, it can be backtracked to include less or more cervical sensory plexus depending on the amount of CN VII that was resected, and it combines a good diameter with a monofascicular structure, similar to CN VII itself. The
Total conservative parotidectomy (TCP), radical parotidec­tomy, and extended radical parotidectomy are procedures indicated for more extensive parotid tumours. The type and extent of procedure is determined by the extent of the tumour. Wherever possible, the facial nerve should be preserved, and it is important to have adequately counselled the patient and planned for reconstruction if facial nerve resection is required.
GAN thus has an adequate arborization, which helps in over­coming numerical and size discrepancies in bridging facial nerve defects [29]. Alternatively, the sural nerve can be used, but it is polyfascicular, has no (or far less) arborization, and
ment of malignant tumours, invariably postoperative radio­therapy must follow, because it doubles locoregional control and improves survival [33].
is not in the surgical eld [30]. Successful reinnervation depends on tension-free epineurial anastomoses, after trim­ming the nerve endings (so that the epineurium coincides perfectly with the transected axons on both sides) [6].
Limited defects can be addressed by primary closure or a cervicofacial rotation ap; more extended defects, can be
References
1. Patey D, Thackray AC. The treatment of parotid tumours in the
addressed by a cervicodeltopectoral ap [6]. Raising these aps also provides access for a neck dissection. Neck skin laxity allows for rotation of skin with a good texture and colour match into the defect, and the donor site can usually be closed primarily [28]. For large defects (up to 13×7cm)
2. Martin H. The operative removal tumors of the parotid salivary
3. Patey DH.The treatment of mixed tumours of the parotid gland. Br
4. McFarland J.Three hundred mixed tumors of the salivary glands, of
in patients who are unt for free aps, Behan et al. [31] recently described “keystone island aps” based on occipital and posterior auricular perforators. A relatively easy alterna-
5. Deschler DG, Eisele DW. Surgery for primary malignant parotid
6. Lombardi D, McGurk M, Vander Poorten V, Guzzo M, Accorona
tive in these circumstances is the supraclavicular artery island ap (SCAIF), which allows a substantial amount of
When this type of extended surgery is needed in the treat-
light of a pathological study of parotidectomy material. Br J Surg. 1958;45:477–87.
gland. Surgery. 1952;31:670–82.
J Surg. 1940;28:29–38.
which sixty-nine recurred. Surg Gynecol Obstet. 1936;63:457–68.
neoplasms. Adv Otorhinolaryngol. 2016;78:83–94.
R, Rampinelli V, Nicolai P.Surgical treatment of salivary malignant tumors. Oral Oncol. 2017;65:102–13.
178
https://t.me/med1917
V. VanderPoorten and M. Elliott
7. Quer M, Guntinas-Lichius O, Marchal F, Vander Poorten V, Chevalier D, León X, et al. Classication of parotidectomies: a proposal of the European Salivary Gland Society. Eur Arch Otorhinolaryngol. 2016;273:3307–12.
8. Leverstein H, van der Wal JE, Tiwari RM, Tobi H, van der Waal I, Mehta DM, Snow GB.Malignant epithelial parotid gland tumours: analysis and results in 65 previously untreated patients. Br J Surg. 1998;85:1267–72.
9. Terhaard CH, Lubsen H, Van Der Tweel I, Hilgers FJ, Eijkenboom WM, Marres HA, et al. Salivary gland carcinoma: independent prognostic factors for locoregional control, distant metastases, and overall survival: results of the Dutch Head and Neck Oncology Cooperative Group. Head Neck. 2004;26:681–93.
10. Cracchiolo JR, Shaha AR. Parotidectomy for parotid cancer. Otolaryngol Clin North Am. 2016;49:415–24.
11. O’Brien CJ, McNeil EB, McMahon JD, Pathak I, Lauer CS, Jackson MA.Signicance of clinical stage, extent of surgery, and pathologic ndings in metastatic cutaneous squamous carcinoma of the parotid gland. Head Neck. 2002;24:417–22.
12. Thom JJ, Moore EJ, Price DL, Kasperbauer JL, Starkman SJ, Olsen KD.The role of total parotidectomy for metastatic cutaneous squa­mous cell carcinoma and malignant melanoma. JAMA Otolaryngol Head Neck Surg. 2014;140:548–54.
13. Olsen KD, Moore EJ.Deep lobe parotidectomy: clinical rationale in the management of primary and metastatic cancer. Eur Arch Otorhinolaryngol. 2014;271:1181–5.
14. Frankenthaler RA, Byers RM, Luna MA, Callender DL, Wolf P, Goepfert H. Predicting occult lymph node metastasis in parotid cancer. Arch Otolaryngol Head Neck Surg. 1993;119:517–20.
15. Lim YC, Lee SY, Kim K, Lee JS, Koo BS, Shin HA, Choi EC.Conservative parotidectomy for the treatment of parotid can­cers. Oral Oncol. 2005;41:1021–7.
16. Kirkbride P, Liu FF, O’Sullivan B, Payne D, Warde P, Gullane P, etal. Outcome of curative management of malignant tumours of the parotid gland. J Otolaryngol. 2001;30:271–9.
17. Herman MP, Werning JW, Morris CG, Kirwan JM, Amdur RJ, Mendenhall WM.Elective neck management for high-grade sali­vary gland carcinoma. Am J Otolaryngol. 2013;34:205–8.
18. Vander Poorten V, Hart A, Vauterin T, Jeunen G, Schoenaers J, Hamoir M, etal. Prognostic index for patients with parotid carci­noma: international external validation in a Belgian-German data­base. Cancer. 2009;115:540–50.
19. Chen AM, Granchi PJ, Garcia J, Bucci MK, Fu KK, Eisele DW.Local-regional recurrence after surgery without postoperative irradiation for carcinomas of the major salivary glands: implications for adjuvant therapy. Int J Radiat Oncol Biol Phys. 2007;67:982–7.
20. Olsen KD, Quer M, de Bree R, Vander Poorten V, Rinaldo A, Ferlito A.Deep lobe parotidectomy-why, when, and how? Eur Arch Otorhinolaryngol. 2017;274:4073–8.
21. Klussmann JP, Ponert T, Mueller RP, Dienes HP, Guntinas-Lichius O.Patterns of lymph node spread and its inuence on outcome in resectable parotid cancer. Eur J Surg Oncol. 2008;34:932–7.
22. Stennert E, Kisner D, Jungehuelsing M, Guntinas-Lichius O, Schroder U, Eckel HE, Klussmann JP. High incidence of lymph node metastasis in major salivary gland cancer. Arch Otolaryngol Head Neck Surg. 2003;129:720–3.
23. Guntinas-Lichius O, Eisele DW. Facial nerve monitoring. Adv Otorhinolaryngol. 2016;78:46–52.
24. Makeieff M, Venail F, Cartier C, Garrel R, Crampette L, Guerrier B. Continuous facial nerve monitoring during pleomorphic ade­noma recurrence surgery. Laryngoscope. 2005;115:1310–4.
25. Sood AJ, Houlton JJ, Nguyen SA, Gillespie MB. Facial nerve monitoring during parotidectomy: a systematic review and meta­analysis. Otolaryngol Head Neck Surg. 2015;152:631–7.
26. George M, Karkos PD, Dwivedi RC, Leong SC, Kim D, Repanos C. Preservation of greater auricular nerve during parotidectomy: sensation, quality of life, and morbidity issues. A systematic review. Head Neck. 2014;36:603–8.
27. Diamond M, Wartmann CT, Tubbs RS, Shoja MM, Cohen-Gadol AA, Loukas M.Peripheral facial nerve communications and their clinical implications. Clin Anat. 2011;24:10–8.
28. Ch'ng S, Ashford BG, Gao K, McGuinness J, Clark JR. Reconstruction of post-radical parotidectomy defects. Plast Reconstr Surg. 2012;129:275e–87e.
29. Stennert E.Facial nerve reconstruction. In: Myers EN, Ferris RL, editors. Salivary gland disorders. Berlin: Springer; 2007. p.407–19.
30. Lee MC, Kim DH, Jeon YR, Rah DK, Lew DH, Choi EC, Lee WJ.Functional outcomes of multiple sural nerve grafts for facial nerve defects after tumor-ablative surgery. Arch Plast Surg. 2015;42:461–8.
31. Behan FC, Lo CH, Sizeland A, Pham T, Findlay M. Keystone Island ap reconstruction of parotid defects. Plast Reconstr Surg. 2012;130:36e–41e.
32. Emerick KS, Herr MW, Lin DT, Santos F, Deschler DG.Supraclavicular artery Island ap for reconstruction of com­plex parotidectomy, lateral skull base, and total auriculectomy defects. JAMA Otolaryngol Head Neck Surg. 2014;140:861–6.
33. Terhaard CH, Lubsen H, Rasch CR, Levendag PC, Kaanders HH, Tjho-Heslinga RE, etal. The role of radiotherapy in the treatment of malignant salivary gland tumors. Int J Radiat Oncol Biol Phys. 2005;61:103–11.
Part VII
https://t.me/med1917
Salivary Gland Surgery: Submandibular Gland
Surgery
Transoral Removal ofIntracanalicular
https://t.me/med1917
Stones intheSubmandibular Glands
JonathanB.Gottlieb andLukeCascarini
18
18.1 Introduction
In the past two decades, the eld of major salivary gland obstructive disease has shifted towards minimally invasive, organ-preserving techniques, with the main aim of preserv­ing the affected gland and its function. Transoral release of intracanalicular stones in the submandibular gland (a quite easy and safe procedure) is such a minimally invasive, organ­preserving surgical technique, which should be employed before turning to sialadenectomy of the affected gland.
The main cause of nonneoplastic obstructive major salivary gland disease is the formation of an intraductal sialolithiasis in 60–70% of cases, followed by a stenotic duct in 15–25% of cases, inammation of the duct (sialodochitis) in 5–10% of cases, and other causes, such as anatomic variations or foreign bodies, in 1–3% of cases [13]. Postmortem studies indicate that salivary stones are present in 1.2% of the population [4]. Furthermore, more recent studies estimate their annual symp­tomatic incidence at 1 per 10,000 to 20,000 individuals [5], or up to 60 cases per million [6]. According to the literature, about 3% of all sialolithiasis cases are reported in children [7].
The submandibular glands (SMGs) are the most com­monly affected glands (80–90%), followed by the parotid glands (PG) (5–20%). Sialolithiasis is only rarely discovered in the sublingual glands, and very rarely in the minor salivary glands [8]. The predominant prevalence of stones in the SMG is well known and is explained by anatomic factors such as a longer, tortuous path and the general ascending direction of the duct, as well as the narrower papilla of the
Wharton’s duct compared with the Stenson’s papilla. Another factor may be the thicker, mucoid composition of saliva in the SMG versus the serous, more viscous composition of saliva in the parotid gland [9].
In a recent study by Sigismund etal. [10] of 2378 SMG stones, the distribution within the submandibular ductal sys­tem was found to be mainly in the proximal duct system (53%), followed by 37% within the distal duct system, and only 10% located in the intraparenchymal duct system (Fig.18.1).
In the past two decades we have seen the evolution of sialendoscopy, a minimally invasive technique which allows intraductal stone removal & preserving a functional gland [5] important is the work of Marchal etal. [11], who examined histologically 48 consecutive submandibular adenectomies due to sialolithiasis; they found that the gland was normal in most of the cases, supporting the idea of organ preservation when dealing with salivary stones and allowing clinicians to develop and provide conserva­tive nonsurgical and surgical techniques for the manage­ment of SMG sialolithiasis. This approach was validated by a multicenter trial of minimally invasive management of calculi by Iro etal. [12], which included 4691 patients treated by techniques that included salivary lithotripsy, basket extraction, and/or gland- preserving surgery. The overall outcome was 80.5% complete stone removal and
16.6% partial stone removal, with only 2.9% of cases requiring sialadenectomy of the affected gland owing to sialolithiasis, which was previously the main cause of sali­vary gland excision.
J. B. Gottlieb (*) Salivary Gland Service, The Oral and Maxillofacial Surgery Unit, Carmel Medical Center, Haifa, Israel
Salivary Gland Service, The Oral and Maxillofacial Surgery Unit, Carmel Medical Center, Haifa, Israel
L. Cascarini Department of Oral and Maxillofacial, Head and Neck Surgery, Guy’s Hospital, London, UK e-mail: luke.cascarini@gstt.nhs.uk
© Springer Nature Switzerland AG 2024 R. Simo et al. (eds.), Atlas of Head and Neck Surgery, Springer Surgery Atlas Series,
https://doi.org/10.1007/978-3-031-36593-5_18
181