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Intracranial Vascular Anatomy
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The paired PCA are the terminal branches of the bas-
ilar artery and complete the posterior circle of Willis (Fig. 31.34). The PCA can be described in three main sec- tions: P1, from the origin to PcomA; P2, running around the cerebral peduncle; and P3, posterior to the midbrain to the anterior limit of the calcarine fissure. The main trunk continues posteriorly and terminates by dividing into parieto-occipital and occipital branches, with the calcarine artery usually arising from the latter. The P1 section passes around the front of the cerebral peduncle, above the cranial nerves III and IV, and receives the Pco­mA at the level of the cranial nerve III. The thalamoper- forating arteries arise predominantly from this segment. The P2 section then runs laterally and posteriorly (parallel to the SCA) to reach the inferior surface of the temporal lobe. It runs in the ambient cistern, whose anterior por­tion is sometimes called the crural cistern. The P3 section continues in the ambient cistern and then in the lateral part of the quadrigeminal cistern. As it runs posteriorly, the PCA turns toward the midline, under the splenium of the corpus callosum. The PCA gives origin to a large num­ber of small arteries which supply mesencephalon and diencephalon structures and the choroid plexus.
27
References
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Internal Carotid Artery: An Atlas for Skull Base Surgeons. Berlin, Germany: Springer; 2013
2. Cavallo LM, Messina A, Gardner P, et al. Extended endoscopic en-
donasal approach to the pterygopalatine fossa: anatomical study and clinical considerations. Neurosurg Focus 2005;19(1):E5
3. Vescan AD, Snyderman CH, Carrau RL, et al. Vidian canal: analy-
sis and relationship to the internal carotid artery. Laryngoscope 2007;117(8):1338–1342
4. Falcon RT, Rivera-Serrano CM, Miranda JF, et al. Endoscopic
endonasal dissection of the infratemporal fossa: Anatomic rela­tionships and importance of eustachian tube in the endoscopic skull base surgery. Laryngoscope 2011;121(1):31–41
5. Ziyal IM, Ozgen T, Sekhar LN, Ozcan OE, Cekirge S. Proposed clas-
sification of segments of the internal carotid artery: anatomi­cal study with angiographical interpretation. Neurol Med Chir (Tokyo) 2005;45(4):184–190, discussion 190–191
6. Jinkins JR. Atlas of Neuroradiologic Embryology, Anatomy, and
variants. Philadelphia, PA: Lippincott Williams & Wilkins; 2000
7. Conti M, Prevedello DM, Madhok R, et al. The antero-medial tri-
angle: the risk for cranial nerves ischemia at the cavernous sinus lateral wall. Anatomic cadaveric study. Clin Neurol Neurosurg 2008;110(7):682–686
8. Bolzoni Villaret A, Battaglia P, Tschabitscher M, et al. A 3-dimen-
sional transnasal endoscopic journey through the paranasal sinuses and adjacent skull base: a practical and surgery-oriented perspective. Neurosurgery 2014;10(Suppl 1):116–120, discussion 120
9. Parkinson D. Collateral circulation of cavernous carotid artery:
anatomy. Can J Surg 1964;7:251–268
10. Yasuda A, Campero A, Martins C, Rhoton AL Jr, Ribas GC. The medi­al wall of the cavernous sinus: microsurgical anatomy. Neurosur­gery 2004;55(1):179–189, discussion 189–190
11. Tubbs RS, Hansasuta A, Loukas M, et al. Branches of the petrous and cavernous segments of the internal carotid artery. Clin Anat 2007;20(6):596–601
12. Krisht A, Barnett DW, Barrow DL, Bonner G. The blood supply of the intracavernous cranial nerves: an anatomic study. Neurosur­gery 1994;34(2):275–279, discussion 279
13. Reisch R, Vutskits L, Filippi R, Patonay L, Fries G, Perneczky A. Topographic microsurgical anatomy of the paraclinoid carotid artery. Neurosurg Rev 2002;25(3):177–183
14. Fields WS. The significance of persistent trigeminal artery. Carot­id-Basilar anastomosis. Radiology 1968;91(6):1095–1101
15. Silver JM, Wilkins RH. Persistent embryonic intracranial and extra­cranial vessels. In: Wilkins RH, Rengachary SS, eds. Neurosurgery Update II Vascular, Spinal, Pediatric, and Functional Neurosurgery. New York, NY: McGraw-Hill; 1991
16. Suttner N, Mura J, Tedeschi H, et al. Persistent trigeminal artery: a unique anatomic specimen—analysis and therapeutic implica­tions. Neurosurgery 2000;47(2):428–433, discussion 433–434
17. Salas E, Ziyal IM, Sekhar LN, Wright DC. Persistent trigeminal artery: an anatomic study. Neurosurgery 1998;43(3):557–561, discussion 561–562
18. Yasargil MG. Intracranial arteries. In: Yasargil MG, ed. Microneuro­surgery. Stuttgart: Georg Thieme; 1984:54–164
19. Dolenc VV. Anatomy and surgery of the Cavernous Sinus. New York, NY: Springer; 1989
20. Inoue T, Rhoton AL Jr, Theele D, Barry ME. Surgical approach­es to the cavernous sinus: a microsurgical study. Neurosurgery 1990;26(6):903–932
21. Lasjaunias PL. Craniofacial and Upper Cervical Arteries: Function­al, Clinical and Angiographic Aspects. Baltimore, MD: Lippincott Williams & Wilkins; 1981
22. Labib MA, Prevedello DM, Carrau R, et al. A road map to the inter­nal carotid artery in expanded endoscopic endonasal approaches to the ventral cranial base. Neurosurgery 2014;10(Suppl 3):448– 471, discussion 471
23. Martins C, de Alencastro LF, Cardoso ACC, et al. Anatomy of the nasal cavity and paranasal sinuses. In: Stamm AC, ed. Transnasal Endoscopic Skull Base and Brain Surgery: Tips and Pearls. New York, NY: Thieme; 2011
24. Yasuda A, Campero A, Martins C, Rhoton AL Jr, de Oliveira E, Ri­bas GC. Microsurgical anatomy and approaches to the cavernous sinus. Neurosurgery 2005; 56(1, Suppl):4–27, discussion 4–27
25. Cavallo LM, Messina A, Cappabianca P, et al. Endoscopic endonasal surgery of the midline skull base: anatomical study and clinical considerations. Neurosurg Focus 2005;19(1):E2
26. Kassam A, Snyderman CH, Mintz A, Gardner P, Carrau RL. Expand­ed endonasal approach: the rostrocaudal axis. Part I. Crista galli to the sella turcica. Neurosurg Focus 2005;19(1):E3
27. Rhoton AL Jr. Cranial Anatomy and Surgical Approaches. Philadel­phia, PA: Lippincott Williams & Wilkins; 2003
28. Lang J. Skull base and Related Structures: Atlas of Clinical Anato­my. Stuttgart: Schattauer; 1995
29. Perlmutter D, Rhoton AL Jr. Microsurgical anatomy of the anteri­or cerebral-anterior communicating-recurrent artery complex. J Neurosurg 1976;45(3):259–272
30. McCormick WF. Vascular disorder of nervous tissue: anomalies, malformations and aneurisms. The structure and function of ner­vous tissue. In: Bourne GH, ed. Biochemistry and Disease. New York, NY: Academic Press; 1969
31. Kassam AB, Prevedello DM, Carrau RL, et al. The front door to meckel’s cave: an anteromedial corridor via expanded endoscop­ic endonasal approach- technical considerations and clinical se­ries. Neurosurgery 2009; 64(3, Suppl):ons71–ons82, discussion ons82–ons83
32. Janfaza P, Nadol JB Jr. Scalp, cranium, and brain. In: Janfaza P, Nadol JB Jr, Galla R, Fabian RL, Montgomery WW, eds. Surgical Anato­my of the Head and Neck. Philadelphia, PA: Lippincott Williams & Wilkins; 2001
33. Martins C, Yasuda A, Campero A, et al. Microsurgical and endo­scopic anatomy of the parasellar region. In: Stamm AC, ed. Trans­nasal Endoscopic Skull Base and Brain Surgery: Tips and pearls. New York, NY: Thieme; 2011
34. Kassam AB, Gardner P, Snyderman C, Mintz A, Carrau R. Expand­ed endonasal approach: fully endoscopic, completely transna­sal approach to the middle third of the clivus, petrous bone, middle cranial fossa, and infratemporal fossa. Neurosurg Focus 2005;19(1):E6
35. Iaconetta G, de Notaris M, Benet A, et al. The trochlear nerve: micro­anatomic and endoscopic study. Neurosurg Rev 2013;36(2):227– 237, discussion 237–238
36. Tubbs RS, Mortazavi MM, Krishnamurthy S, Verma K, Griessenauer CJ, Cohen-Gadol AA. The relationship between the superior petro­sal sinus and the porus trigeminus: an anatomical study. J Neuro­surg 2013;119(5):1221–1225
37. Roche PH, Mercier P, Sameshima T, Fournier HD. Surgical anatomy of the jugular foramen. Adv Tech Stand Neurosurg 2008;33:233–263
38. Mortazavi MM, Griessenauer CJ, Krishnamurthy S, Verma K, Lou­kas M, Tubbs RS. The inferior petrosal sinus: a comprehensive review with emphasis on clinical implications. Childs Nerv Syst 2014;30(5):831–834
39. Kassam A, Snyderman CH, Mintz A, Gardner P, Carrau RL. Ex­panded endonasal approach: the rostrocaudal axis. Part II. Posterior clinoids to the foramen magnum. Neurosurg Focus 2005;19(1):E4
40. Cavallo LM, Cappabianca P, Messina A, et al. The extended endo­scopic endonasal approach to the clivus and cranio-vertebral junc­tion: anatomical study. Childs Nerv Syst 2007;23(6):665–671
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Chapter 32
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32.1 Surgical Steps 348
Anteromedial
Corridors to the
Cranial Nerves
32.2 Tips and Tricks 357
Anteromedial Corridors to the Cranial Nerves
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32 Anteromedial Corridors to the Cranial Nerves
Juanita M. Celix, Srikant S. Chakravarthi, Nishit Shah, Martin Corsten, Sammy Khalili, Amin Kassam, Melanie Fukui, Richard Rovin
Introduction
Access to the skull base utilizes four primary approaches: anteromedial, anterolateral, lateral, and posterolateral. The location of the pathology in relation to the crani­al nerves (CNs) is the primary determining factor when deciding which approach to utilize. We have previously described the concept of selecting the operative corridor based on the position of the CN. of the ventral skull base grows from its basal origin (e.g., meningiomas, chondrosarcomas), often displacing the critical CNs along its dorsal perimeter. In such situations, the traditional lateral approaches provide a trajectory that results in encountering the CNs first, followed by the pathology. The CNs are sensitive to manipulation, and deficits can occur following even the gentlest handling of the nerve. Therefore, the guiding principle in the deci­sion-making process is to avoid crossing the plane of a CN when accessing a tumor or other lesion.
The evolution of minimally invasive techniques has led to a concomitant evolution of minimally invasive approaches to the skull base. The goal of minimally invasive skull base approaches is to minimize surgical morbidity using anatomically-directed corridors. This reduces the need for brain retraction and unnecessary tissue exposure. The endoscopic endonasal approach (EEA) to the skull base provides safe access to the medial anterior, middle, and posterior cranial fossa along both sagittal (median) and coronal (paramedian) planes from an anteromedial trajectory. This median corridor provides the most direct access to the entire ventral skull base, including CNs. The anteromedial approaches to the anterior, middle, and posterior fossa can be grouped into median and paramedian approaches. The median approaches will be limited laterally by critical neurovascular structures, while the paramedian approaches may be limited both medially and laterally. A combination of median and paramedian approaches to the skull base allows access to CNs I–XII.
In the following sections, we describe the common anteromedial corridors to address ventral pathology affecting each of the CNs. We also identify the extradural sinonasal corridor used to access each region. Given that the endoscope requires physical space in the nares, we generally suggest a “cavity and a half” sinonasal corridor. We have previously described this concept, which provides one-half nasal cavity for visualization and manipulation of the endoscope and the remaining one-half nasal cavity and full contralateral nasal cavity (“cavity and a half”) for bimanual dissection.
1
In general, pathology
2
transplanum approach described below. The rostral as­pect of the transplanum approach is extended further rostral to the level of the crista galli or the frontal sinus. The attachment of the anterior nasal septum to the skull base is resected. Normally this maneuver would damage the olfactory epithelium at the upper nasal cavity, but it is often performed when olfaction is already compromised. Bilateral ethmoidectomies are performed to expose the medial orbital walls. To gain lateral exposure, the lamina papyracea can be removed. The skull base is then drilled in a rostrocaudal direction starting at the frontoethmoidal recess. The anterior and posterior ethmoidal arteries are identified and transected. The nasal mucosa, olfactory filaments, and ethmoidal artery branches are coagulated and the cribriform plate is removed bilaterally. The crista galli is egg-shelled and fractured. The dura is opened and both olfactory nerves can be seen (Fig. 32.1).
The boundaries of this approach are the frontal sinus anteriorly, the lamina papyracea laterally, and the pla­num sphenoidale at the level of the posterior ethmoidal arteries posteriorly. A wide bilateral frontal sinus Draf III approach rior and anterior ethmoidectomies will provide the full cavity for the working corridor. The transcribriform ap­proach and the unique anatomy of the olfactory nerve fibers represent the rare exception to the guiding prin­ciple of never crossing the plane of a CN in the approach to a lesion. In this exposure, the nasociliary mucosa and the distal fibers of the olfactory nerve in the cribriform plate are destroyed and olfaction is sacrificed. Therefore, this approach is generally reserved for those conditions in which olfaction has already been lost. We have previously published on the ability to preserve olfaction via a unilat­eral approach with preservation of the contralateral side,
4
provides the half cavity, while bilateral poste-
32.1 Surgical Steps
32.1.1 Median Approaches to Anterior Cranial Fossa—CN I: Olfactory Nerve
The olfactory nerve and bulb (CN I) can be accessed via an anteromedial transcribriform approach. scribriform approach is typically combined with the
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3
The tran-
Fig. 32.1 Endoscopic view after an anterior transcribriform approach. The dura of the anterior cranial base has been opened and the olfactory nerve (ON) can be seen in the depth.
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though this is a rare exception.5 The primary indication for the transcribriform approach is a mass that has al­ready created anosmia. This approach offers the ability to minimize retraction and manipulation of the frontal lobe.
32.1.2 Median Approaches to Anterior Cranial Fossa—CN II: Optic Nerve
The optic nerve (CN II) to the optic chiasm can be accessed via the median endonasal transsellar and expanded endonasal transplanum/transtuberculum approaches. The general technique for bilateral expo­sure using the binasal approach is utilized to gain ac­cess to the sphenoid sinus.3 Bilateral sphenoidotomies are completed and widened laterally to the carotid canal, superiorly to the posterior ethmoid sinus, and posteriorly along the floor of the sphenoid to the cli-
superior intercavernous sinus (SIS) is exposed, and the sellar face, parasellar carotid protuberance, medial op­ticocarotid recess (mOCR), and bone overlying the SIS are identified. The mOCR is a key anatomic landmark in expanded endoscopic anterior skull base exposures. The superior extent of the carotid protuberance marks the mOCR, specifically, the confluence of the tubercu­lar strut and the middle clinoid (when present). Entry at this level allows for access to the optic canal, which travels obliquely in a posteromedial to anterolateral trajectory. In the transsellar approach, bone removal over the sellar face extends laterally to expose the medial cavernous sinus, and superoinferiorly to expose the superior and inferior cavernous sinus, respectively. This allows downward retraction of the sellar contents and facilitates working space; however, the intrasellar
dura mater is opened and an intrasellar dissection is performed only when needed. At the superolateral aspect of the sellae, the optic nerve, internal carotid artery (ICA), and mOCR can be identified.
Extension of the transsellar approach rostrally allows access to the suprasellar cistern and anterior cranial fos­sa floor via a transplanum/transtuberculum approach without going through the sellae turcica. provides access to the optic canals and optic chiasm. Fol­lowing a general bilateral transsphenoidal approach, the rostral extension begins with wide bilateral posterior ethmoidectomies, extending superiorly to the anterior cranial fossa floor and laterally to the lamina papyracea, which is the medial wall of the orbit. The anterior mar­gin of the exposure is the posterior ethmoidal arteries, which travel in the posterior ethmoidal canals (Fig. 32.2). The posterior ethmoidal canal courses from the lamina papyracea laterally to the fovea ethmoidalis medially. The dissection is limited to the posterior ethmoidal arteries as the anterior margin to avoid injuring the olfactory fil­aments and creating anosmia. The planum sphenoidale is removed in a caudal to rostral direction with a V-shaped lateral osteotomy to avoid injuring the optic canal (Fig. 32.3). The rostral portion of the sellar floor can be opened to the SIS, and the SIS mobilized to allow access to the suprasellar parachiasmatic cisterns (Fig. 32.4). This approach provides a cranial base opening that extends posteriorly from the junction of the cribriform plate and planum sphenoidale to the clival recess, and to the lamina papyracea bilaterally (Fig. 32.5). The dura mater is opened and the paraclinoid ICA identified as it enters the dura at the level of the mOCR. The ICA can be followed superiorly to identify the optic nerve, which can be followed to the optic chiasm and the contralateral optic nerve. The optic canals at the orbital apex represent the lateral limit of the transplanum/transtuberculum approach.
3
This approach
OC
Fig. 32.2 Right posterior ethmoidectomy and lateral sphenoidectomy completed. Expansion to the left is being undertaken. Note the anterior margin of the ethmoidectomy is the posterior ethmoidal artery (PEA). Also note the position of the optic canal (OC).
PEA
Fig. 32.3 The tuberculum and planum V-osteotomies have been performed providing for a rostral exposure. The dura is now opened along the interfalciform ligament (IF).
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Fig. 32.4 Optional sectioning of the superior intercavernous sinus (SIS) is performed to provide for a complete sellar and suprasellar exposure.
32.1.3 Paramedian Approaches to Anterior Cranial Fossa—CN II
The optic nerve passes anterolateral through the optic foramen and along the optic canal to enter the orbit, where it can be accessed via the paramedian medial tran­sorbital approach. moidectomies described above, the medial transorbital approach requires removal of the lamina papyracea and medial optic canal to gain access to the annulus of Zinn. The lamina papyracea is fractured and elevated from the orbital floor to the anterior skull base, and posteriorly to the orbital apex. The bone of the orbital apex to the supe­rior orbital fissure can be removed to expose the intracan­alicular optic nerve. To gain access to the intraconal space, the periorbita is opened, and the superior rectus muscle, medial rectus muscle, and/or superior oblique muscle are identified and mobilized. This will often require a transconjunctival incision. Following mobilization of the superomedial extraocular muscles, a corridor between the extraocular muscles provides direct access to the optic nerve in the orbit (Fig. 32.6). The surgeon can then fol­low the intradural optic nerve from proximal to distal to the annulus of Zinn and the intraorbital optic nerve from distal to proximal to the annulus of Zinn. Care must be taken to avoid manipulating the ophthalmic artery, which is tethered at this point, and the emerging central retinal artery, as either can be avulsed resulting in vison loss.
1,3,6
Following the bilateral sphenoeth-
Fig. 32.5 Bilateral sphenoidotomies and posterior ethmoidectomies (posterior to the posterior ethmoidal arteries) have been undertaken. The sellar contents are displaced downward following bony removal of the sellae, tuberculum, and planum.
SR
ON
AZ
OF
MR
Fig. 32.6 Paramedian exposure following removal of the lamina papyracea and exposure of the extraocular muscles. Superior (SR) and medial rectus (MR) muscles are, respectively, mobilized just distal to the annulus of Zinn (AZ). The optic nerve (ON) in the intraconal space can be seen as the orbital fat (OF) is mobilized. Note the pituitary gland (PT) has been transposed superiorly and out of the sellae, covering the optic chiasm.
PT
32.1.4 Median Approaches to Middle Cranial Fossa—CNs III–VI
Cranial Nerve III: Oculomotor Nerve
The oculomotor nerve (CN III) emerges from the ventral midbrain in the interpeduncular fossa, travelling between the posterior cerebral and superior cerebellar arteries and traversing the interpeduncular cistern. CN III occupies a
350
consequential position emerging from the interpeduncular cistern. Its relationship to the P1 and P2 segments, the bas­ilar apex located medially, and the uncus of the temporal lobe positioned laterally along the tentorial edge, is critical. This relationship explains why temporal (uncal) herniation leads to an ipsilateral dilated pupil (CN III compression), followed by P1 perforator compromise, and midbrain Duret hemorrhage in that specific temporal sequence. CN III courses between the borders of the tentorium cerebelli,
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and pierces the dura to enter the cavernous sinus, where it travels within the lateral wall of the cavernous sinus to enter the orbit through the superior orbital fissure.
Cranial Nerve IV: Trochlear Nerve
The trochlear nerve (CN IV) emerges from the dorsal mid­brain, crosses to the contralateral side, and courses around the cerebral peduncle in the cerebellomesencephalic fis­sure to enter the ambient cistern. It passes between the posterior cerebral and superior cerebellar arteries and along the inferior surface of the tentorium to pierce the dura and enter the cavernous sinus, where it courses in the lateral wall inferior to the oculomotor nerve before enter­ing the orbit through the superior orbital fissure.
Cranial Nerve V: Trigeminal Nerve
The trigeminal nerve (CN V) arises from the lateral pons and courses obliquely superior, passing beneath the ten­torial attachment and above the petrous apex to enter Meckel’s cave, where it separates into three sensory di­visions. The ophthalmic branch (V1) rises obliquely to enter the cavernous sinus and travel lateral to the abdu­cens nerve. V1 passes in the lateral wall of the cavernous sinus inferior to the trochlear nerve before entering the orbit through the superior orbital fissure. The maxillary
ON
PCR
V1
CS
V2
AN
branch (V2) functionally forms the upper boundary of Meckel’s cave, entering the pterygopalatine fossa through the foramen rotundum. The mandibular branch (V3) functionally forms the inferolateral boundary of Meckel’s cave, exiting through the foramen ovale into the pterygopalatine fossa.
The quadrangular space (Fig. 32.7) represents an an­atomic boundary (i.e., parallel oblique lines) marking the location of Meckel’s cave. The quadrangular space is defined medially by the ascending paraclival ICA, inferi­orly by the petrous ICA, laterally, for practical purpose, by V3, and superiorly by the abducens nerve, or by surrogacy V2. The Gasserian ganglion is considered the trunk of the trigeminal nerve, located in the middle of Meckel’s cave, with the sensory divisions V1, V2, and V3 emerging.
Cranial Nerve VI: Abducens Nerve
The abducens nerve (CN VI) arises from the midline ven­tral pontomedullary junction, approximately 4 mm from the vertebrobasilar junction, then courses through the pre­pontine cistern anterolateral to pierce the dura and travel between the periosteal and meningeal layers of the dura in the Dorello canal. Within the Dorello canal, at approx­imately the level of the dorsum sellae in the region of the confluence of the sinuses at the venous gulf, the abducens nerve makes an acute medial to lateral bend marking its horizontal genu. The nerve turns horizontal and courses behind the carotid artery emerging from the Dorello canal just lateral to the ICA (Fig. 32.8), and enters the cavern­ous sinus coursing freely in the lateral wall lateral to the carotid artery. The abducens nerve then forms its second genu, turning vertical and running obliquely through the cavernous sinus, tucked on the underside of V1 as it enters the orbit through the superior orbital fissure (Fig. 32.9).
To gain access to the intradural/intracisternal seg­ments of the ventral CN III, CN IV, V1, V2, V3, and CN VI,
V3
Fig. 32.7 Endoscopic view of the critical landmarks of the quadrangular space. The quadrangular space (yellow box) is identifi ed, marking the location of Meckel’s cave. The gasserian ganglion (GG) is seen as the trunk of the trigeminal nerve located in the middle of Meckel’s cave, with the sensory divisions V1, V2, and V3 emerging. The abducens nerve (AN) is seen leaving the Dorello canal and forming the second vertical genu as it rises and travels freely within the cavernous sinus (CS) on its way to the superior orbital fi ssure tucked under V1. The maxillary division (V2) functionally serves as the superolateral extent of the quadrangle to protect the abducens nerve as it travels and can be seen exiting from the Dorello canal through the cavernous sinus on its way to the superior orbital fi ssure (see also Fig. 32.15). FL, foramen lacerum; ON, optic nerve; PCR, paraclival recess; VN, vidian nerve.
VN
GG
AN
V2
Paraclival
GG
ICA
Petrous
ICA
Fig. 32.8 The paraclival ICA is peeled away from the meningeal layer of Meckel’s cave that houses the gasserian ganglion (GG) and trigeminal divisions. The abducens nerve (AN) can be seen emerging from the Dorello canal and behind the paraclival ICA, forming the second vertical genu to enter the cavernous sinus.
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via a median approach, the space immediately behind the pituitary gland and infundibulum must be opened. This is a compact space anatomically bounded by the optic apparatus and anterior recess of the third ventricle superiorly, the mammillary bodies and interpeduncular cistern posteriorly, the oculomotor nerve and posterior communicating artery bilaterally, and the sellae anterior­ly. Access to this space from a median approach requires a transsphenoidal corridor, and the pituitary gland must be transposed. We have previously described the technique of pituitary transposition at length. wide bilateral sphenoidotomies and wide removal of the tuberculum sellae, the sequence proceeds as follows:
1. The sellar and suprasellar dura are opened and the pituitary ligaments released laterally.
2. The central pituitary aperture is opened to expose the pituitary stalk, and the stalk followed superiorly to release it from the diaphragma (Fig. 32.10).
3. Once the pituitary aperture is completely opened and the pituitary stalk freed, the pituitary gland is mobi­lized rostrally along the stalk in the direction of the superior hypophyseal artery to avoid compromising the blood supply.
4. Transposition of the pituitary gland exposes the en­tire posterior wall of the sellae. The dura is dissected posteriorly and superiorly to expose the dorsum sel­lae and posterior clinoids.
5. Removal of the dorsum sellae is extended through the upper third of the clivus. Care is taken during removal of the dorsum to avoid injury to the ICA as it transi­tions caudal to rostral from the paraclival segment to the cavernous segment at the level of the abducens nerve in the region of the Dorello canal laterally.
6. The posterior clinoids are removed via an intradural or extradural technique. We prefer an extradural tech­nique. This requires a complete shoulder osteotomy, removing the dorsum sellae and leaving the posterior clinoids in place (Fig. 32.11). En bloc removal of the
7
Briefly, following
posterior clinoids with the dorsum sellae is dangerous, as the posterior clinoids are wrapped around the ICA and can lacerate the ICA when removed en bloc.
7. Once the dorsum sellae is resected, the posterior cli­noids are carefully mobilized from a lateral to medial direction from behind the ICA and removed individu­ally (Fig. 32.12a-b).
The pituitary transposition provides an unparalleled view into the interpeduncular fossa, extending from the mid­brain through the pons and exposing all of the neurovas­cular structures within (Fig. 32.13). A key understanding of the confluence of the various arachnoid membranes forming the anatomic boundaries of the respective cis­terns is critical. From rostral to caudal, these cisterns in­clude the prechiasmatic cistern, the suprasellar cistern, and the membrane of Liliequist/interpeduncular cistern. The aponeurosis of many of these cisterns is represented by the diaphragma itself.
32.1.5 Paramedian Approaches to
Middle Cranial Fossa—CNs III–VI
As the cavernous ICA is the lateral boundary of a medi­an approach, the CNs coursing lateral to the ICA can be accessed via a paramedian EEA. CN III, CN IV, V1, V2, and CN VI in the cavernous sinus can be accessed via the para­median transpterygoid inferior cavernous sinus/quad­rangular space approach and superior cavernous sinus approach, while CN III, CN IV, V1, and CN VI in the su­perior orbital fissure can be accessed via the paramedian temporal/infratemporal approach.
The transpterygoid approach is the starting approach for the paramedian trajectory to the middle cranial fossa.8 This approach requires a wide maxillary antrostomy or medial maxillectomy to provide access to the posterior wall of the maxillary sinus. Removal of the posterior max­illary sinus wall provides access to the pterygopalatine
V2
Fig. 32.9 The abducens nerve (AN) after the second vertical genu traveling freely within the cavernous sinus. V2, maxillary division of trigeminal nerve.
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AN
PS
PT
Fig. 32.10 Releasing the pituitary gland (PT) from the diaphragma. The pituitary gland and pituitary stalk (PS) are exposed.
Anteromedial Corridors to the Cranial Nerves
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fossa (see Chapter 16 on Meckel’s cave). In the pterygopal­atine fossa, the soft tissues are elevated laterally to expose the base of the pterygoid process. At the superomedial sphenopalatine junction is the sphenopalatine foramen, through which pass the sphenopalatine artery and nerve. In the superior aspect of the posterior sphenoid bone is the foramen rotundum, with the vidian canal immediately inferior to it. The vidian canal is a key anatomic landmark in the paramedian approach to the middle cranial fossa. Posteriorly, the vidian canal is directed toward the anteri­or genu of the petrous ICA as it angles superiorly to form the paraclival ICA (Figs. 32.14 and 32.15). The medial pter­ygoid plate is another key anatomic landmark. The medial pterygoid plate is drilled inferior and medial to the vidian canal, following the canal posteriorly toward the foramen
PT
PC
DS
Fig. 32.11 Shoulder osteotomies are performed to allow removal of the dorsum sellae (DS) while leaving the posterior clinoids (PC) in position. PT, pituitary gland.
lacerum. The anterior genu of the petrous ICA is identified at the foramen lacerum. Following identification of the ICA, the lateral and superior portions of the medial ptery­goid plate can be drilled. This allows complete exposure of the lateral sphenoid recess.
The inferior cavernous sinus/quadrangular space approach then follows.
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The posterior wall of the max­illary antrum is removed laterally and the maxillary branch of the trigeminal nerve is identified. V2 is followed posteriorly to the foramen rotundum. The bone between V2 and the vidian canal is removed to access the quad­rangular space. The bone covering the parasellar ICA is removed widely from medial to lateral to expose the en­tire parasellar ICA. The ICA can be further skeletonized by removing the bone over the horizontal petrous segment laterally under V2. The dura of the inferior cavernous si­nus is opened medially from the genu of the ICA to V2 lat­erally to expose V1, V2, and CN VI in the lower cavernous sinus (Fig. 32.15).
The superior cavernous sinus approach follows the same exposure as the inferior cavernous sinus/quadrangular space approach. Once the superolateral portion of the cav­ernous sinus is exposed, the dura above the quadrangular space is opened in a medial to lateral direction to expose the oculomotor and abducens nerves in the superior cav­ernous sinus. Opening the superior and inferior cavernous sinus allows access to CN III, CN IV, V1, V2, and CN VI.
The temporal/infratemporal approach follows the transpterygoid and quadrangular space approach.
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With the lateral sphenoid recess exposed, tissue dissection ensues laterally to the lateral pterygoid plate. The inter­nal maxillary artery is encountered and ligated. The lat­eral pterygoid plate is removed rostrally to the level of the foramen ovale in the middle cranial fossa floor and V3 is identified. V2 exiting the foramen rotundum is identified and bone superior to foramen rotundum is removed to the level of the superior orbital fissure. The dura at the superior orbital fissure can be opened to expose CN III, CN IV, V1, and CN VI (Fig. 32.16).
a
Fig. 32.12 (a) Upper third clivectomy is performed and the pituitary gland (PT) is lifted up extradurally. The dorsum sellae has been resected via shoulder osteotomies, leaving the posterior clinoids (PC) in place. (b) The posterior clinoid on the left is mobilized from behind the ICA. The posterior clinoid on the right has already been removed. C, clivus.
PT
PC
ICA
C
b
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Anteromedial Corridors to the Cranial Nerves
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ACom
C
PCA
III
Fig. 32.13 View following pituitary transposition with pituitary gland moved back into anatomic position. Magnifi ed view of the pituitary gland and parasellar space following removal of the osseous and soft-tissue framework. The oculomotor nerve (III) can be seen, as well as the contents of the interpeduncular cistern with posterior cerebral artery P1 segments (PCA) emerging above CN III. The optic chiasm (C) and anterior communicating artery (Acom) are seen above. PS, pituitary stalk.
V2
V3
GG
PS
ON
CS
AN
Paraclival
PCR
Cavernous
ICA
ICA
VI
Paraclinoidal
ICA
Cavernous
ICA
ICA
III
IV
ON
OS
Sella
O
V2
Fig. 32.14 View of the critical relationship of the great tubercles: the optic strut (OS) between the optic nerve (ON) and the paraclinoid ICA; the lateral opticocarotid recess (LOCR) between the optic nerve (ON) and the superior orbital fi ssure (SOF); and the maxillary strut (MS) between the SOF and V2. The maxillary strut is being removed to gain access to Meckel’s cave by allowing an unencumbered superior mobilization of V2. O, orbit.
LOCR
MS
Paraclival
V1
AN
Fig. 32.15 View following removal of the key bony tubercles (maxillary strut and lingular process). This now provides a direct view of Meckel’s cave. Note the relationship of V2 superolateral and the paraclival ICA medial, with the inferomedial border of the quadrangular space marked by the vidian nerve (VN). The paraclival ICA segment continues in a caudal to rostral direction, transitioning into the cavernous ICA segment at the level of the abducens nerve and then transitioning into the paraclinoid ICA segment at the level of the proximal carotid ring as it enters the cave (see also Fig. 32.7).
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VN
Fig. 32.16 The superior orbital fi ssure is opened and the oculomotor nerve (III), trochlear nerve (IV), ophthalmic division (V1), and abducens nerve (AN) can be visualized.
The paramedian medial petrous apex approach is used
to access CN VI at the Dorello canal.
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This approach is an extension of the paramedian transpterygoid approach to the middle cranial fossa described above and the median transclival approach to the posterior cranial fossa de­scribed below. The anterior genu of the petrous ICA is ex­posed, including removal of bone lateral to the ICA. This