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Chapter 10. Pediatric Burns
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14. Rosado N, Charleston E, Gregg M, Lorenz D. Characteristics of accidental versus abusive pediatric burn injuries in an urban burn center over a 14-year period. J Burn Care Res. 2019;40(4):437–43. https://doi.org/10.1093/jbcr/irz032.
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Rowan MP, Chung KK. A survey of temperature management practices among burn centers in North America. J Burn Care Res. 2018;39(4):612–7. https://doi.org/10.1093/jbcr/irx034.
18. Shah AR, Liao LF.Pediatric burn care: unique considerations in management. Clin Plast Surg. 2017;44(3):603–10. https://doi.
org/10.1016/j.cps.2017.02.017.
19. Monstrey S, Hoeksema H, Verbelen J, Pirayesh A, Blondeel P. Assessment of burn depth and burn wound healing potential. Burns. 2008;34(6):761–9. https://doi.org/10.1016/j.
burns.2008.01.009.
20. Lund CC, Browder NC. The estimation of areas of burns. Surg Gynecol Obstet. 1944;79:352–8.
21. Palmieri TL. Pediatric burn resuscitation. Crit Care Clin. 2016;32(4):547–59. https://doi.org/10.1016/j.ccc.2016.06.004.
22. Hurst J, Johnson D, Campbell R, Baxter S, Kratky V. Orbital compartment syndrome in a burn patient without aggressive fluid resuscitation. Orbit. 2014;33(5):375–7.
23. Campos JK, Wong YM, Hasty BN, et al. The effect of socioeconomic status and parental demographics on activation of department of child and family services in pediatric burn injury. J Burn Care Res. 2017;38:e722–33.
24. Sheridan RL.Burns in children. J Burn Care Res. 2017;38(3):e618–
24. https://doi.org/10.1097/BCR.0000000000000536.
25. Müller Dittrich MH, Brunow de Carvalho W, Lopes LE. Evaluation of the "Early" use of albumin in children with extensive burns: a randomized controlled trial. Pediatr Crit Care Med. 2016;17(6):e280–6. https://doi.org/10.1097/
PCC.0000000000000728.
26. Eljaiek R, Heylbroeck C, Dubois MJ. Albumin administration for fluid resuscitation in burn patients: a systematic review and meta-analysis. Burns. 2017;43(1):17–24. https://doi.org/10.1016/j.
burns.2016.08.001.
2 7. Jeschke MG, Herndon DN. Burns in children: standard and
new treatments. Lancet. 2014;383(9923):1168–78. https://doi.
org/10.1016/S0140- 6736(13)61093- 4.
28. Peeters Y, Vandervelden S, Wise R, et al. An overview on fluid resuscitation and resuscitation endpoints in burns: Past, present and future. Part 1—Historical background, resuscitation fluid and adjunctive treatment. Anaesthesiol Intensive Ther. 2015;47:6–14.
Chapter 10. Pediatric Burns
29. Sheridan R. Less is more-revisiting burn resuscitation. Pediatr Crit Care Med. 2016;17(6):578–9. https://doi.org/10.1097/
PCC.0000000000000747.
30. Navickis RJ, Greenhalgh DG, Wilkes MM. Albumin in burn shock resuscitation: a meta-analysis of controlled clinical studies. J Burn Care Res. 2016;37(3):e268–78. https://doi.org/10.1097/
BCR.0000000000000201.
31. Fagin A, Palmieri TL.Considerations for pediatric burn sedation and analgesia. Burns Trauma. 2017;5:28. https://doi.org/10.1186/
s41038- 017- 0094- 8.
32. Pardesi O, Fuzaylov G. Pain management in pediatric burn patients: review of recent literature and future directions. J Burn Care Res. 2017;38(6):335–47. https://doi.org/10.1097/
BCR.0000000000000470.
33. de Jong AE, Bremer M, van Komen R, et al. Pain in young children with burns: extent, course and influencing factors. Burns. 2014;40:38–47.
34. Cuignet O, Pirson J, Soudon O, Zizi M. Effects of gabapentin on morphine consumption and pain in severely burned patients. Burns. 2007;33:81–6.
35. Jones LM, Uribe AA, Coffey R, Puente EG, Abdel-Rasoul M, Murphy CV, Bergese SD. Pregabalin in the reduction of pain and opioid consumption after burn injuries: a preliminary, randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(18):e15343. https://doi.org/10.1097/
MD.0000000000015343.
36. Shank ES, Sheridan RL, Ryan CM, Keaney TJ, Martyn JA.Hemodynamic responses to dexmedetomidine in critically injured intubated pediatric burned patients: a preliminary study. J Burn Care Res. 2013;34(3):311–7. https://doi.org/10.1097/
BCR.0b013e318257d94a.
3 7. Fagin A, Palmieri T, Greenhalgh D, Sen S. A comparison
of dexmedetomidine and midazolam for sedation in severe pediatric burn injury. J Burn Care Res. 2012;33(6):759–63.
https://doi.org/10.1097/BCR.0b013e318254d48e.
38. Owens VF, Palmieri TL, Comroe CM, Conroy JM, Scavone JA, Greenhalgh DG. Ketamine: a safe and effective agent for painful procedures in the pediatric burn patient. J Burn Care Res. 2006;27(2):211–6; discussion 217. https://doi.org/10.1097/01.
BCR.0000204310.67594.A1.
39. Hansen JK, Voss J, Ganatra H, Langner T, Chalise P, Stokes S, Bhavsar D, Kovac AL.Sedation and analgesia during pediatric
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burn dressing change: a survey of American Burn Association Centers. J Burn Care Res. 2019;40(3):287–93. https://doi.
org/10.1093/jbcr/irz023.
40. Poonai N, Spohn J, Vandermeer B, Ali S, Bhatt M, Hendrikx S, Trottier ED, Sabhaney V, Shah A, Joubert G, Hartling L. Intranasal dexmedetomidine for procedural distress in children: a systematic review. Pediatrics. 2020;145(1):e20191623.
https://doi.org/10.1542/peds.2019- 1623.
41. Baarslag MA, Allegaert K, Knibbe CAJ, van Dijk M, Tibboel. Pharmacological sedation management in the paediatric intensive care unit. J Pharm Pharmacol. 2017;69(5):498–513.
42. Paddock HN, Fabia R, Giles S, et al. A silver-impregnated antimicrobial dressing reduces hospital costs for pediatric burn patients. J Pediatr Surg. 2007;42:211–3.
43. Hartstein B.Burn injuries in children and the use of biological dressings. Pediatr Emerg Care. 2013;29:939–45.
44. Gotschall CS, Morrison MIS, Eichelberger MR. Prospective, randomized study of the efficacy of mepitel on children with partial thickness scalds. J Burn Care Rehabil. 1998;19:279–83.
45. Israel JS, Greenhalgh DG, Gibson AL. Variations in burn excision and grafting: a survey of the American Burn Association. J Burn Care Res. 2017;38(1):e125–32. https://doi.org/10.1097/
BCR.0000000000000475.
46. Gray DT, Pine RW, Harnar TJ, Marvin JA, Engrav LH, Heimbach DM. Early surgical excision versus conventional therapy in patients with 20 to 40 percent burns. A comparative study. Am J Surg. 1982;144:76–80.
4 7. Sargent RL.Management of blisters in the partial-thickness burn:
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81. https://doi.org/10.1097/01.bcr.0000191961.95907.b1.
48. Wang C, Zhang F, Lineaweaver WC. Clinical applications of allograft skin in burn care. Ann Plast Surg. 2020;84(3S Suppl
2):S158–60. https://doi.org/10.1097/SAP.0000000000002282.
49. Choi YH, Cho YS, Lee JH, Choi Y, Noh SY, Park S, Sung C, Lim JK, Kim J, Shin JJ, Yang B, Jeong J, Chun H, Kim KJ.Cadaver skin allograft may improve mortality rate for burns involving over 30% of total body surface area: a propensity score analysis of data from four burn centers. Cell Tissue Bank. 2018;19(4):645–
51. https://doi.org/10.1007/s10561- 018- 9715- 0.
50. Diegidio P, Hermiz SJ, Ortiz-Pujols S, Jones SW, van Duin D, Weber DJ, Cairns BA, Hultman CS. Even better than the real thing? Xenografting in pediatric patients with scald
Chapter 10. Pediatric Burns
injury. Clin Plast Surg. 2017;44(3):651–6. https://doi.org/10.1016/j.
cps.2017.02.001.
51. Palmieri TL, Taylor S, Lawless M, Curri T, Sen S, Greenhalgh DG.Burn center volume makes a difference for burned children. Pediatr Crit Care Med. 2015;16(4):319–24. https://doi.org/10.1097/
PCC.0000000000000366.
52. De La Cruz Monroy MFI, Kalaskar DM, Rauf KG. Tissue expansion reconstruction of head and neck burn injuries in paediatric patients—a systematic review. JPRAS Open. 2018;18:78–97. https://doi.org/10.1016/j.jpra.2018.10.004.
53. Abellan Lopez M, Serror K, Chaouat M, Mimoun M, Boccara D. Tissue expansion of the lower limb: Retrospective study of 141 procedures in burn sequelae. Burns. 2018;44(7):1851–7.
https://doi.org/10.1016/j.burns.2018.03.021.
54. Ziegler B, Hundeshagen G, Will PA, Bickert B, Kneser U, Hirche C. Role, management, and outcome of free flap reconstruction for acute full-thickness burns in hands. Ann Plast Surg. 2020;85(2):115–21. https://doi.org/10.1097/
SAP.0000000000002412.
55. Patel SP, Nguyen HV, Mannschreck D, Redett RJ, Puttgen KB, Stewart FD. Fractional CO2 laser treatment outcomes for pediatric hypertrophic burn scars. J Burn Care Res. 2019;40(4):386–91. https://doi.org/10.1093/jbcr/irz046.
56. Zuccaro J, Muser I, Singh M, Yu J, Kelly C, Fish J.Laser therapy for pediatric burn scars: focusing on a combined treatment approach. J Burn Care Res. 2018;39(3):457–62. https://doi.
org/10.1093/jbcr/irx008.
5 7. D'Cruz R, Martin HC, Holland AJ. Medical management of
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Chapter 11
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Elderly Burns
RobynRichmond andSharmilaDissanaike
Introduction
The 2010 United States Census shows that the fastest growing demographic is people over the age of 65years [1]. A similar pattern is seen across the globe, and this trend is expected to continue over the coming decade. With an increasing elderly population nationwide and worldwide, all healthcare providers need to understand the influence of age on various medical conditions; burns are no exception.
The elderly sustain burns more commonly than younger adults, and their burns mostly occur at home [2, 3]. Because of decreased alertness, impaired cognition, and slower reac­tion time, their ability to escape from harm is diminished [4,
5]. Impaired mobility can lead to greater contact time with
the thermal agent, resulting in larger total body surface area (TBSA) affected, deeper burns, and an increase in inhala­tional injury [6, 7].
R. Richmond (*) · S. Dissanaike Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, TX, USA e-mail: robyn.richmond@ttuhsc.edu; sharmila.dissanaike@ttuhsc.edu
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023 J. O. Lee (ed.), Essential Burn Care for Non-Burn Specialists,
https://doi.org/10.1007/978-3-031-28898-2_11
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R. Richmond and S. Dissanaike
Initial Assessment andResuscitation
The Advanced Burn Life Support course recommends a standardized approach to the burned patient, starting with initial assessment [8]. The primary survey follows a systematic assessment of life and/or limb-threatening injuries [8]. Although the primary survey remains the same in the elderly patient, there are several anatomic and physiologic changes that impact initial assessment that should be considered.
When assessing the airway in elderly burn patients, it is important to recognize that they are more likely to have loss of protective airway reflexes, making aspiration more likely [9]. Dentition can also affect the airway; poor dentition as well as dentures can affect the ability to bag-valve-mask and result in ineffective ventilation. Dentures may also become dislodged and occlude the airway [9]. One tip is to keep den­tures in place during bag-valve-mask ventilation to improve the mask seal, but to remove dentures for intubation. Checking for loose teeth prior to intubation is another important step to guard against dislodgement and aspiration. Range of mouth opening may be decreased, which can affect the ability to open the mouth using standard “scissor” manual technique during endotracheal intubation. Cervical immobil­ity secondary to age and/or arthritis can impede neck exten­sion making intubation more difficult [9]. Proper positioning with support under the shoulders can improve visualization during intubation, as can video laryngoscopes if available.
Elderly patients have decreased lung and chest wall compliance, which can impair their ability to maintain normal oxygenation and ventilation at baseline [10]. This places them at high risk for respiratory failure [10]. Because of a limited ability to increase their heart rate, they typically are less likely to manifest tachycardia associated with hypoxia, which can make respiratory failure more insidious and difficult to diag­nose [9]. Early recognition of impending respiratory failure is critical to prevent patients from emergent intubation with possible cardiovascular collapse.
Chapter 11. Elderly Burns
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257
The circulatory system in the elderly has significant changes compared to younger counterparts. The heart rate and cardiac output are more likely to be fixed for a number of reasons, including a blunted response to catecholamines [11]. In addition to a blunted response to catecholamines, myocyte mass decreases and afterload increases with age which can contribute to a depressed cardiac function. A fixed heart rate may also be a manifestation of a prescribed antihy­pertensive or antiarrhythmic medication. In the setting of shock, a decrease in the ability to increase heart rate and cardiac output results in significant vasoconstriction to main­tain perfusion [12]. This response, in addition to hypertension in many elderly patients, results in relative normotension masking hypotension and hypoperfusion [12]. Because of this, a systolic blood pressure of 110mmHg can be considered hypotensive in some elderly [12].
Burn resuscitation in the elderly should look similar to younger patients, and use of defined end points such as lac­tate, base deficit, and other organ system perfusion indicators are important. It should be noted, however, that use of advanced monitoring may be necessary in the elderly due to their physiologic differences and possible pre-existing condi­tions [9, 12].
Physiologic changes to the renal system with age include a decreased glomerular filtration rate and a decreased sensitiv­ity to antidiuretic hormone [13]. This will affect the body’s ability to concentrate urine, making urine output as a marker of tissue perfusion potentially unreliable [13]. The elderly are also at an increased risk for acute kidney injury, making resuscitation and maintenance of renal perfusion critical in these patients [13]. In addition, avoidance of nephrotoxic agents is important to prevent acute kidney injury.
The endocrine system is also affected by the aging process, with occult hypothyroidism and adrenal insufficiency being common [14]. These should be screened for and treated accordingly.
Loss of subcutaneous fat will affect depth of burn in the elderly, with similar burns resulting in a deeper burn in an
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R. Richmond and S. Dissanaike
older compared to a younger patient [15]. Thinner atrophic skin also puts the elderly at an increased risk for hypothermia following a large burn [16]. Avoidance and active treatment of hypothermia are critical in any burn patient. Ensuring warm rooms, warm blankets, and warmed intravenous fluids are easy first steps in caring for burn patients. More aggres­sive central warming measures with central venous devices, gastric tubes, urinary catheters, thoracostomy, or intra­abdominal devices should be considered in severely hypo­thermic patients if initial rewarming attempts are ineffective. In addition to loss of subcutaneous fat, reduced microcircula­tion and reduced turnover rate of the epidermis lead to pro­longed wound healing in the elderly [16, 17].
Pre-existing Conditions andMedications
Knowledge of a patient’s history, including pre-existing conditions (PECs) and home medications, is critical for care following burn injury. Elderly patients are more likely to suffer from PECs which can affect their response to injury, their response to resuscitation, and increase the likelihood of complications including mortality.
PECs that are associated with an increased mortality in trauma patients from one statewide database include liver disease, renal disease, cancer, and congestive heart failure [18]. Another large study identified five PECs that influence outcome in trauma: cirrhosis, congenital coagulopathy, chronic obstructive pulmonary disease (COPD), ischemic heart disease, and diabetes [19]. In addition, one quarter of all patients in that study greater than 65years carried the diag­nosis of at least one of the above listed PECs [19]. The burn literature also suggests that PECs increase the likelihood of complications following burns [20].
In addition to PECs, elderly patients are more likely to take daily, scheduled medications, both prescription and over the counter. One important consideration is beta blockers. Beta blockers are used in approximately 20% of elderly
Chapter 11. Elderly Burns
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patients with coronary artery disease and 10% of patients with hypertension [21]. Consumption of beta blockers can impair interpretation of the physiologic response to a burn.
Anticoagulants and antiplatelets are also frequently taken by the elderly. Since these agents impair blood clotting, their effects must be considered when planning surgical treatment of burns. When present, it is important to weigh the conse­quences of stopping these agents, which may vary from a minor risk of stroke in a patient with atrial fibrillation and a low CHA2DS2-VASc score to a major risk of in-stent throm­bosis and death, in a patient who has recently received drug­eluting stents for critical coronary stenosis. A thoughtful plan to manage these competing risks, balance them against the need for surgery, and prevent bleeding both intra-operatively and in the immediate post-operative period, must be developed.
Since COPD is a common disease in the elderly, most commonly from emphysema after a lifetime of smoking, it is not unusual to see burn injuries sustained while smoking on oxygen; in fact, this is an injury pattern unique to this demo­graphic. Smoking related burn injuries involving home oxy­gen can carry a significant morbidity and mortality, most notably when inhalational injury is present and intubation is required [22, 23]. One series cites a relatively high mortality rate of over 14% despite most patients having a relatively low TBSA burn (less than 5%) [22]. In another review of the American Burn Association (ABA)’s National Burn Repository, inhalational injury was found to be the strongest predictor of mortality [23]. This is likely due to the baseline disease state in these patients, and if inhalational injury exists and intubation is required in these already pulmonary compromised patients, they are more likely to have pro­longed intubation, possible tracheostomy, and a discharge destination other than home [23]. Inhalation injuries derived from smoking on oxygen are a phenomenon seen in patients with end-stage COPD. These patients almost always have other medical comorbidities that can complicate their medi­cal course. The outcome in these cases is primarily depen-