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17 Total Conservative andRadical Parotidectomy
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Table 17.1 European Salivary Gland Society (ESGS) classication:
nonparotid structures that may need removal
Symbol Denition
CN VII Facial nerve trunk and/or all the main
branches
CN VII t-z-b-m-c Facial nerve branchesa: temporal, zygomatic,
buccal, marginal mandibular, cervical
ECA External carotid artery
GAN Greater auricular nerve
LTB Lateral temporal bone
MB Mastoid bone
MM Masseter muscle
S Skin
TMJ Temporomandibular joint
PPS Parapharyngeal space
ESGS classication: Comparison with classic descriptions
ESGS classication Classic classication
Parotidectomy I–IV
(VII)
Parotidectomy I–IV Total parotidectomy with facial nerve
Parotidectomy I–IV
(VII, S, MM)
a
When all the nerves have been sacriced, just use “CN VII,” but when
the surgeon has sacriced just some branches, then “CN VII z,” for
example, means the surgeon has removed only the zygomatic branches
Total parotidectomy with facial nerve
resection
preservation
Extended total parotidectomy with facial
nerve resection plus skin and masseter muscle
resection
a
In certain circumstances, small, isolated malignant
tumours of the parotid gland can also be managed with partial parotidectomy preserving the facial nerve branches.
Wide surgical margins are not possible with facial nerve–
preserving parotid surgery, as these tumours are almost
always intimately associated with one or more branches of
the facial nerve. “Wide surgical” resection would involve
sacrice of one or more of these nerves. A signicant proportion of patients with malignant parotid tumours will also
receive adjuvant radiotherapy, questioning the additional
benet of more radical parotid surgery.
17.2.2 Indications forTotal Conservative
Parotidectomy
Total conservative parotidectomy (TCP) is much less commonly performed and is limited to certain circumstances.
TCP may be considered as a last resort for situations such as
chronic sialadenitis and rst bite syndrome following parapharyngeal space surgery, but it is rarely required, because
other effective treatment modalities such as Botox are
available.
a b
Fig. 17.2 The European Salivary Gland Society (ESGS) division in
ve levels. A case of supercial parotidectomy showing the four levels.
The separation between superior and inferior levels is established with
an imaginary line connecting the bifurcation of the facial nerve main
trunk (F) in its two major branches (temporofacial and cervicofacial)
with Stensen’s duct (St). Five ESGS levels: I (lateral superior), II (lateral inferior), III (deep inferior, under CN VII), IV (deep superior, under
CN VII), V (accessory)

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17.2.2.1 TCP forBenign Tumours
TCP is indicated for multifocal recurrent pleomorphic adenoma, as an ultimate attempt to remove all parotid tissues
encompassing what may be many tiny foci of pleomorphic
adenoma. TCP is also performed when removing a superiorly located deep-lobe parotid tumour (ESGS level IV, high
tumours abutting the facial nerve from beneath), when the
facial nerve is stretched over the tumour. CN VII thus must
be identied rst, dissected, and released off the deep-lobe
tumour so as to facilitate the tumour’s safe removal whilst
preserving the nerve’s integrity.
17.2.2.2 TCP forMalignant Tumours
If the facial nerve is functioning normally before surgery, the
aim should be to preserve the nerve [6]. Even for high-grade
parotid cancers, long-term local control can be obtained with
facial nerve preservation if only microscopic residual disease
is left and is treated with postoperative radiotherapy [5, 8, 9].
It is also important to keep in mind that, theoretically, in
many situations, “The tumour can be radically removed from
the nerve (by cutting it), but not from the patient.” This
means that one should not aim for a wide margin at the level
of CN VII if close margins are expected at other levels in the
surgical eld.
TCP is required in several situations [6, 10]:
• Intraparotid metastatic lymph nodes
• Malignant tumours of the deep lobe
• A large, grossly inltrative malignant tumour with extraparenchymal extension in surrounding structures such as
the masseter muscle, mastoid bone, lateral temporal bone,
or temporomandibular joint
• Parotid tumours with extensive neck nodal metastasis
Performing a total parotidectomy also has strong propo-
nents when dealing with skin cancer metastasis to the parotid,
although no prospective data support this approach. O’Brien
etal. [11] observed a 20% local recurrence rate (two-thirds
in the deep parotid lobe bed) in 87 skin cancer patients with
clinical parotid metastasis, most of whom had been treated
with a supercial parotidectomy (82%) and despite adjuvant
radiation (86%). It is unclear whether leaving tissue deep to
CN VII was the origin of recurrence, but the authors made a
case for performing total parotidectomy in these instances.
This approach is supported by Olsen et al. [12, 13]. Total
parotidectomy for metastatic squamous cell carcinoma in
their patients resulted in parotid control rates of 93% at a
median follow-up of 36.4months.
As with partial parotidectomy, TCP remains an area of
discussion for malignant parotid tumours in the supercial
lobe, with low T classication and pre-operatively known
high grade [5, 6, 10]. Many authors would say that a supercial parotidectomy is sufcient, relying on postoperative
radiotherapy to control potential microscopic disease and/or
involved deep-lobe parotid lymph nodes [14–19]. Some
authors stay in the middle and suggest that one should
“inspect and resect the deep lobe if there is suspicion of deep
lobe nodal metastasis” [5]. Other authors suggest proceeding
with TCP in these specic situations, observing a high rate of
intraparotid lymph node metastasis in resected deep parotid
lobes [13, 20–22]. This area of controversy would certainly
benet from additional prospective research.
17.2.3 Indications forRadical Parotidectomy,
ESGS I–V (VII)
In the setting of preoperative facial nerve paresis or palsy,
resection of the nerve is indicated, with the extent of resection
guided by the abnormality of the facial nerve on MRI scan
and/or intraoperative frozen section. The facial nerve can be
chased proximally into the temporal bone, as indicated by
frozen section. One can also encounter intraoperative nerve
entrapment with carcinoma in the setting of a functioning
nerve; this situation requires facial nerve sacrice for oncological resection.
An absolute indication for CN VII resection is preoperative nerve dysfunction, with the exception of the preoperative or perioperative (frozen section) diagnosis of parotid
lymphoma. Relative indications include imaging studies
(MRI) showing gross inltrative malignant disease on the
course of CN VII (Fig.17.3). In this circumstance, the patient
is counselled preoperatively about the potential for facial
nerve sacrice and reconstruction using static or dynamic
reanimation.
Depending on preoperative imaging and perioperative
ndings, the radical parotidectomy can be extended to
involve resection of adjacent nonparotid structures involved
Fig. 17.3 MRI showing gross inltrative malignant disease on the
course of the right CN VII (arrow). In this circumstance, the patient is
counselled preoperatively about the potential for facial nerve sacrice
and reconstruction using static or dynamic reanimation

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with cancer, such as all those listed on Table17.1, and can
involve an appropriate neck dissection based on nodal metastatic disease [6, 10].
17.3 Surgical Technique
17.3.1 Facial Nerve Monitoring
The use of facial nerve monitoring is controversial and is
based on the surgeon’s individual preference and on individual surgical situations. Guntinas-Lichius and Eisele [23]
conclude, in their recent review, that facial nerve monitoring
is reasonable in all instances where facial nerve identication, dissection, and preservation are potentially difcult;
surgery for malignant and difcult benign tumours is
included in their list. Makeieff etal. [24] found in their study
on recurrent pleomorphic adenoma that both the rate of facial
nerve palsy and the duration of the procedure were signicantly reduced when using CN VII monitoring. Sood etal.
[25] performed a meta-analysis and concluded that “the
number needed to treat” was nine, so in order to prevent one
immediate postoperative CN VII dysfunction, nine patients
needed to be monitored. Facial nerve monitoring should be
considered for revision surgical cases, patients with prior
radiotherapy, patients with extensive tumours, and patients
in whom radical parotidectomy is being performed and identication of distal facial nerve branches is required for
reconstruction.
17.3.2 Incision Planning andExecution
A number of incisions have been described, including a
Blair, modied Blair, and facelift incision. A modied Blair
or lazy S incision, with or without a retrotragal part at the
upper part of the incision, is usually preferable over a facelift
incision, for it provides better access with less dissection and
is more readily prolonged into an extension for a neck dissection. Planning of the skin incision also must take into
account potential resection of overlying skin if it is involved
in cancer.
The skin ap dissection is preferably done in the subSMAS plane if the tumour does not extend that far supercially. The greater auricular nerve (GAN) is identied in the
neck and traced superiorly, with preservation of the posterior
branches of the GAN if possible to minimize postoperative
facial numbness. The GAN can also be used for cable grafting if required [26].
The parotid gland is dissected off the tragal perichondrium and off the sternocleidomastoid muscle (SCM) . The
facial nerve trunk is identied using the most reliable landmark (the tympanomastoid suture) and at the level of the
posterior belly of the digastric. Alternative landmarks such
as the tragal pointer can be used. A retrograde dissection is
sometimes required for tumours arising around the stylomastoid foramen.
17.3.3 Total Conservative Parotidectomy
Whether the tumour is located supercially or deep to CN
VII, the rst step is to perform a complete supercial parotidectomy, as described in Chap. 19 (Fig.17.4). An elegant
technique of subsequently performing an en bloc deep-lobe
parotidectomy with facial nerve preservation has been
described by Olsen and Moore [12]. First, CN VII is separated from the deep lobe with meticulous microdissection.
Operating loupes and micro-instruments (such as used in
microvascular reconstruction) greatly aid in this step. There
uniformly is a branch of CN VII passing into the deep lobe
(the connecting branch to the auriculotemporal nerve, at the
posterior border of the masseter muscle [MM]) [27]. This
branch is divided without effect on the motor function
(Fig.17.5). Anteriorly, the deep parotid lobe is then mobilized off the MM (Fig.17.6). On its inferior aspect, the deep
lobe is mobilized from the stylohyoid, stylopharyngeus, and
posterior digastric muscles. Essential for a controlled en bloc
deep lobe removal is division and ligation of the externa
carotid artery and the retrofacial vein inferiorly (Fig.17.7)
and the supercial temporal artery and the vein superiorly.
Then the deep parotid lobe can be mobilized downward, off
the temporomandibular joint (Fig. 17.8). The nal step is
elevation of the deep lobe off the posterior border of the
mandible. Following division and ligation of the internal
maxillary veins and artery, the deep lobe is then released
from underneath the CN VII branches (Fig.17.9).
In some instances, part of the facial nerve (such as the
buccal branch) must be sacriced. It goes without saying that
cable grafting of a more distally located part of the CN VII
has a more favourable outcome than when a complete defect
from the main trunk to the different peripheral branches has
to be bridged, losing the topographic innervation of the facial
muscles, as outlined in the next paragraph.
17.3.4 Total Radical Parotidectomy; Extended
Radical Parotidectomy
In contrast to a TCP, a radical parotidectomy is more
straightforward as meticulous dissection of the facial nerve
branches is not required. As with TCP, where possible, the
facial nerve trunk is identied at the stylomastoid foramen.
The facial nerve trunk is divided, and a stump is left for
facial nerve grafting. The distal branches are identied and
tagged for later facial nerve grafting. (A nerve monitor

174
a
without effect on the motor function
retromandibular
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V. VanderPoorten and M. Elliott
b
c
Fig. 17.4 Malignant parotid tumour with skin invasion requiring a
conservative total parotidectomy with skin resection (parotidectomy I–
IV (S)) and modied radical neck dissection. (a) Elevation of skin aps
with involved skin attached to the specimen. (b) The situation after
Masseter
Muscle (MM)
Cut
vein
Connecting branch to the auriculotemporal
nerve at the posterior border of the
Masseter Muscle (MM) is divided
Fig. 17.5 CN VII branches are gently microdissected off the underlying deep-lobe parotid parenchyma. The connecting branch to the auriculotemporal nerve, at the posterior border of the masseter muscle
(MM), is divided without effect on the motor function
supercial parotidectomy (ESGS I–II) and neck dissection in progress
and after completion (c) of neck dissection before starting deep lobe
parotidectomy (ESGS III–IV)
greatly assists with this identication.) The resection is carried out as for a TCP.
If there is cancer involving structures beyond the parotid
gland, an extended radical parotidectomy is performed,
removing the involved structure(s). For cancers involving the
ear canal or facial nerve in the temporal bone, a lateral temporal bone resection is performed. Extended radical parotidectomy is often accompanied by a neck dissection
(Fig.17.10). Reconstruction is carried out at the same operation and includes procedures relating to static and dynamic
facial nerve reanimation, as well as reconstruction of soft tissue and/or skin defects.
17.3.5 Wound Closure withor Without
Reconstruction
Ideally, the surgeon will start the resection with a good reconstructive plan, so that obtaining free margins is not compromised by lack of reconstructive possibilities, and sacricing
donor nerves (such as the GAN) and essential donor and accep-

Stylohyoid muscle
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a
b
Fig. 17.6 Anteriorly, the deep parotid lobe is then mobilized off the
MM. (a) Schematic. (b) Real-life situation
tor blood vessels is avoided. When supporting tissues such as
the MM must be resected (resulting in denuded mandibular
bone), the parapharyngeal space (PPS) or infratemporal fossa
tissues or lateral temporal bone composite aps are required to
restore the defect [28]. One can consider using pedicled aps
(pectoralis major myocutaneous and pedicled latissimus dorsi
ap), especially in the unt patient, in failed free-ap reconstructions, or in combination with free-ap reconstructions, but
generally, microvascular free aps are preferred. The anterolateral thigh (ALT) perforator ap can be adapted to the needs and
thus is very popular in this area. It can be dissected suprafascially as a thin cutaneous ap; alternatively, vastus lateralis or
rectus femoris muscle can be included, so that it becomes a
musculocutaneous ap. It combines a relatively constant anatomy, a possible two-team approach (the donor site being at a
distance from the ablative eld), and a long (8–16cm) and
large-calibre (2–2.5 mm) pedicle. When mainly volume is
needed, a de- epithelialized ALT ap combined with a cervicofacial rotation ap can give a superior esthetic result.
When a parotid tumour invades the mandible, the resection will typically result in a lateral mandibular defect with
or without the condyle. For the sake of simplicity, this defect
can be restored with soft tissue reconstruction only (ALT,
latissimus dorsi, rectus abdominis), providing acceptable
speech, mastication, and frontal facial symmetry at rest, but
it entails malocclusion and deviation to the resected side on
mouth opening. Osseous reconstruction generally works
well only when the temporomandibular joint can be pre-
Fig. 17.7 Division and
ligation of the external carotid
artery and retromandibular
vein inferiorly
Stylopharyngeus
muscle
Ligated & cut
external carotid
artery
Ligated & cut
retromandibular
vein

176
temporal artery and
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Fig. 17.8 Division and
ligation of the supercial
temporal artery and the vein
superiorly. Then the deep
parotid lobe can be mobilized
downward, off the
temporomandibular joint
V. VanderPoorten and M. Elliott
Divided superficial
vein
Deep veins
a c
Fig. 17.9 The nal step is division and ligation of the internal maxillary veins and artery (a and b). The deep lobe is then released from underneath
the CN VII branches (c)
b

abc
17 Total Conservative andRadical Parotidectomy
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Fig. 17.10 Clinical (a) and PET-CT images (b) indicate the need for a parotidectomy ESGS I–IV (VII, GAN, MM, lateral temporal bone, external
carotid artery). To the right (c), the resulting postablative situation can be observed
177
served. Then, an osteocutaneous bula ap can restore bone
and skin defects. If additional soft tissue is needed, one can
include the soleus muscle [6].
skin (and subcutaneous soft tissue) to be harvested without
having to perform microvascular anastomosis. This ap can
also be used as a de-epithelialized “ller” ap [32].
Following resection of CN VII, the reconstructive goal is
to allow for facial expression of emotions whilst safeguarding vision, nasal airow, and oral competence. This aim is
17.4 Conclusion
best reached by immediate cable grafting, with static
measures for the eyelid, nasolabial groove, and the angle of
the mouth, which help bridge the period until facial musculature reinnervation is achieved [28]. The best donor nerve
for cable grafting is the GAN: It lies in the operative eld, so
there is easy access, it can be backtracked to include less or
more cervical sensory plexus depending on the amount of
CN VII that was resected, and it combines a good diameter
with a monofascicular structure, similar to CN VII itself. The
Total conservative parotidectomy (TCP), radical parotidectomy, and extended radical parotidectomy are procedures
indicated for more extensive parotid tumours. The type and
extent of procedure is determined by the extent of the tumour.
Wherever possible, the facial nerve should be preserved, and
it is important to have adequately counselled the patient and
planned for reconstruction if facial nerve resection is
required.
GAN thus has an adequate arborization, which helps in overcoming numerical and size discrepancies in bridging facial
nerve defects [29]. Alternatively, the sural nerve can be used,
but it is polyfascicular, has no (or far less) arborization, and
ment of malignant tumours, invariably postoperative radiotherapy must follow, because it doubles locoregional control
and improves survival [33].
is not in the surgical eld [30]. Successful reinnervation
depends on tension-free epineurial anastomoses, after trimming the nerve endings (so that the epineurium coincides
perfectly with the transected axons on both sides) [6].
Limited defects can be addressed by primary closure or a
cervicofacial rotation ap; more extended defects, can be
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Part VII
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Salivary Gland Surgery: Submandibular Gland
Surgery

Transoral Removal ofIntracanalicular
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Stones intheSubmandibular Glands
JonathanB.Gottlieb andLukeCascarini
18
18.1 Introduction
In the past two decades, the eld of major salivary gland
obstructive disease has shifted towards minimally invasive,
organ-preserving techniques, with the main aim of preserving the affected gland and its function. Transoral release of
intracanalicular stones in the submandibular gland (a quite
easy and safe procedure) is such a minimally invasive, organpreserving surgical technique, which should be employed
before turning to sialadenectomy of the affected gland.
The main cause of nonneoplastic obstructive major salivary
gland disease is the formation of an intraductal sialolithiasis in
60–70% of cases, followed by a stenotic duct in 15–25% of
cases, inammation of the duct (sialodochitis) in 5–10% of
cases, and other causes, such as anatomic variations or foreign
bodies, in 1–3% of cases [1–3]. Postmortem studies indicate
that salivary stones are present in 1.2% of the population [4].
Furthermore, more recent studies estimate their annual symptomatic incidence at 1 per 10,000 to 20,000 individuals [5], or
up to 60 cases per million [6]. According to the literature,
about 3% of all sialolithiasis cases are reported in children [7].
The submandibular glands (SMGs) are the most commonly affected glands (80–90%), followed by the parotid
glands (PG) (5–20%). Sialolithiasis is only rarely discovered
in the sublingual glands, and very rarely in the minor salivary
glands [8]. The predominant prevalence of stones in the
SMG is well known and is explained by anatomic factors
such as a longer, tortuous path and the general ascending
direction of the duct, as well as the narrower papilla of the
Wharton’s duct compared with the Stenson’s papilla. Another
factor may be the thicker, mucoid composition of saliva in
the SMG versus the serous, more viscous composition of
saliva in the parotid gland [9].
In a recent study by Sigismund etal. [10] of 2378 SMG
stones, the distribution within the submandibular ductal system was found to be mainly in the proximal duct system
(53%), followed by 37% within the distal duct system, and
only 10% located in the intraparenchymal duct system
(Fig.18.1).
In the past two decades we have seen the evolution of
sialendoscopy, a minimally invasive technique which
allows intraductal stone removal & preserving a functional
gland [5] important is the work of Marchal etal. [11], who
examined histologically 48 consecutive submandibular
adenectomies due to sialolithiasis; they found that the
gland was normal in most of the cases, supporting the idea
of organ preservation when dealing with salivary stones
and allowing clinicians to develop and provide conservative nonsurgical and surgical techniques for the management of SMG sialolithiasis. This approach was validated
by a multicenter trial of minimally invasive management
of calculi by Iro etal. [12], which included 4691 patients
treated by techniques that included salivary lithotripsy,
basket extraction, and/or gland- preserving surgery. The
overall outcome was 80.5% complete stone removal and
16.6% partial stone removal, with only 2.9% of cases
requiring sialadenectomy of the affected gland owing to
sialolithiasis, which was previously the main cause of salivary gland excision.
J. B. Gottlieb (*)
Salivary Gland Service, The Oral and Maxillofacial Surgery Unit,
Carmel Medical Center, Haifa, Israel
Salivary Gland Service, The Oral and Maxillofacial Surgery Unit,
Carmel Medical Center, Haifa, Israel
L. Cascarini
Department of Oral and Maxillofacial, Head and Neck Surgery,
Guy’s Hospital, London, UK
e-mail: luke.cascarini@gstt.nhs.uk
© Springer Nature Switzerland AG 2024
R. Simo et al. (eds.), Atlas of Head and Neck Surgery, Springer Surgery Atlas Series,
https://doi.org/10.1007/978-3-031-36593-5_18
181
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