- •Foreword
- •Preface
- •Acknowledgments
- •Contents
- •Contributors
- •Introduction
- •Resistance to Antimicrobials
- •Bacterial Cells That Persist
- •Markers of Cell Viability
- •Surface Coating
- •Concluding Remarks
- •References
- •A Brief History of the First Studies on Root Canal Anatomy
- •Computational Methods for the Study of Root Canal Anatomy
- •References
- •Introduction
- •Syringes
- •Needles
- •Physical Properties of Irrigants
- •Irrigant Refreshment
- •Wall Shear Stress
- •Apical Vapor Lock
- •Anatomical Challenges
- •Summary: Clinical Tips
- •References
- •Introduction
- •Challenges of Root Canal Irrigation
- •In Vitro: Direct Contact Tests
- •In Vivo Models
- •Sampling Methods
- •Models to Study Cleaning of Isthmus Areas
- •Dentin Canals
- •Lateral Canals
- •Smear Layer
- •New Models to Study Irrigation
- •Measuring Antibacterial Activity
- •Inaccessible Root Canal Areas
- •Particle Image Velocimetry
- •Irrigation Pressure in the Apical Canal
- •Wall Shear Stress/Wall Velocity
- •Needle Design
- •Conclusions
- •References
- •Antiseptic Solutions
- •Sodium Hypochlorite
- •Mode of Action
- •Concentration
- •Volume
- •Time
- •Effect on the Dentin
- •Depth of Penetration
- •Limitations
- •Clinical Recommendation
- •Chlorhexidine Gluconate (CHX) [6]
- •Molecular Structure
- •Mode of Action
- •Substantivity
- •Chlorhexidine as an Endodontic Irrigant
- •Allergic Reactions to Chlorhexidine
- •Limitations
- •Clinical Recommendations
- •Decalcifying Agents
- •Ethylenediaminetetraacetic Acid
- •History
- •Mode of Action
- •Applications in Endodontics
- •Interaction Between CHX and NaOCl
- •Interaction Between CHX and EDTA
- •Interaction Between EDTA and NaOCl
- •Clinical Recommendations
- •HEBP
- •Effect of Temperature
- •NaOCl + Heat
- •EDTA + Heat
- •CHX + Heat
- •Combinations and Solutions with Detergents
- •BioPure MTAD and Tetraclean
- •Mode of Action
- •Smear Layer Removal
- •Clinical Trials
- •Protocol for Use
- •QMiX
- •Protocol
- •Smear Layer Removal
- •Clinical Trials
- •Disinfection Protocol Suggested
- •References
- •Microbial Control: History
- •NaOCl: Cytotoxicity
- •NaOCl: Complications
- •Maxillary Sinus Considerations
- •Intraosseous Injection
- •The Peck Case History
- •Informed Consent
- •Conclusion
- •References
- •Introduction
- •On Apical Transportation
- •Role of the Patency File on Irrigant Penetration into the Apical Third of Root Canals
- •The Use and Effect of the Patency File in Cleaning of the Root Canals in Teeth with Vital Pulps
- •References
- •Static Versus Dynamic Irrigation
- •The Vapor Lock Effect
- •MDA Mode of Use
- •Conclusion
- •References
- •Apical Negative Pressure
- •The EndoVac System
- •Method of Use
- •Debris Removal
- •Microbial Control
- •Smear Layer Removal
- •Apical Vapour Lock
- •Calcium Hydroxide Removal
- •Sodium Hypochlorite Incidents
- •Safety
- •Conclusion
- •References
- •10: Sonic and Ultrasonic Irrigation
- •Introduction
- •Ultrasonic Activation
- •Ultrasonic Energy Generation
- •Debris and Smear Layer Removal
- •Safety
- •Laser-Activated Irrigation (LAI)
- •Sonic Activation
- •Debris and Smear Layer Removal
- •Safety
- •Summary
- •References
- •The Self-Adjusting File (SAF) System
- •The Self-Adjusting File (SAF)
- •The RDT Handpiece Head
- •EndoStation/VATEA Irrigation Pumps
- •Mode of Irrigation by the SAF System
- •Positive Pressure Irrigation
- •Negative Pressure Irrigation
- •No-Pressure Irrigation
- •Mode of Action of EDTA
- •Mode of Cleaning with the SAF System
- •Disinfection of Oval Canals
- •Effect of Cleaning on Obturation
- •The Challenge of Isthmuses
- •The Challenge of Immature Teeth
- •References
- •12: Ozone Application in Endodontics
- •Introduction
- •Applications of Ozone in Medicine
- •Ozone in Dentistry
- •Effects on Dentin Bonding
- •Ozone in Endodontics
- •Antibacterial Activity
- •Antifungal Activity
- •Ozone and Endotoxin
- •Conclusion
- •References
- •Newer Laser Technology
- •PIPS
- •PIPS Protocol
- •References
- •Introduction
- •Conclusion
- •References
- •Introduction
- •History
- •The Rationale for Local Application of Antibiotics
- •Tetracyclines
- •Structure and Mechanisms of Action
- •Properties
- •Applications in Endodontics
- •Substantivity of Tetracyclines
- •MTAD
- •Antimicrobial Activity
- •Substantivity of MTAD
- •Smear Layer Removal and Effect on Dentin
- •Toxicity of MTAD
- •Tetraclean
- •Antibacterial Activity
- •Substantivity of Tetraclean
- •Smear Layer Removal Ability
- •Ledermix Paste
- •Triple Antibiotic Paste
- •Conclusions
- •References
- •16: Intracanal Medication
- •The Infectious Problem
- •Calcium Hydroxide
- •Vehicles for Calcium Hydroxide
- •Mechanisms of Antimicrobial Effects
- •Combination with Biologically Active Vehicles
- •Paste in CPMC
- •Paste in CHX
- •Chlorhexidine Alone for Intracanal Medication
- •Other Intracanal Medicaments
- •Other Indications for Intracanal Medication
- •References
- •Introduction
- •Missing Canals
- •Vertical Root Fracture
- •Infection
- •Removal of Filling Material
- •Carrier-Based Filling Materials
- •Sodium Hypochlorite (NaOCl)
- •Chelants
- •Ethylenediaminetetraacetic Acid (EDTA)
- •Chlorhexidine Digluconate (CHX)
- •Concluding Remarks
- •References
- •Introduction
- •Irrigation Techniques
- •Concluding Remarks
- •References
- •19: Conclusion and Final Remarks
- •Index
5 Update of Endodontic Irrigating Solutions |
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Fig. 5.10 Visual aspect of |
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the interactions between the following: (a) 5.25 % NaOCl and 2 % CHX; (b) 0.16 % NaOCl and 2 % CHX; (c) 17 % EDTA and 2 % CHX (Reproduced with permission from Prado et al. JOE 2007 [68])
solution could be used as a single irrigant during and after instrumentation, replacing the Þnal rinse with a chelating agent [1].
Effect of Temperature
NaOCl + Heat
Increasing the temperature of low-concentration NaOCl solutions improves their immediate tissue-dissolution capacity [98]. Furthermore, heated hypochlorite solutions remove organic debris from dentin shavings more efÞciently. There are various devices to preheat NaOCl syringes; however, it was demonstrated that as soon as the irrigant touches the root canal system, the temperature reaches the body temperature [98]. Therefore, in situ heating of NaOCl is recommended by some authors. This can be done by activating ultrasonic or sonic tips to the NaOCl inside the root canal for a couple of minutes. Cavitation is the formation of vapor cavities in a liquid that are the consequence of forces acting upon the liquid. It usually occurs when a liquid is subjected to rapid changes that cause the formation of cavities where the pressure is relatively low. When subjected to higher pressure, the voids implode and can generate an intense shockwave http://en.wikipedia.org/wiki/Cavitation. Macedo
et al.[53] state that the efÞcacy of NaOCl on the dentin is improved by refreshment, ultrasonic activation, and exposure time. In this investigation, a 10 ¡C temperature rise during ultrasonic activation was insufÞcient to increase the reaction rate. However, to our knowledge, there are no clinical studies available at this point to support the use of heated NaOCl.
EDTA + Heat
The ultrasonic activation and heat production of chelating agents with an ultrasonic tip are also of questionable value. While the streaming of the solution will be enhanced, the generation of heat and the possibility of cavitation may not be beneÞcial. Chelators have a clear temperature range at which they work best. Heating from 20 to 90 ¡C will decrease the calciumbinding capacity of EDTA and citric acid from 219 to 154 and from 195 to 30 mg CaO/g, respectively [97].
CHX + Heat
The use of ultrasonic energy to enhance the efÞcacy of irrigants is a new trend in clinical endodontics. Cameron [11] reported that an increase
