Добавил:
Опубликованный материал нарушает ваши авторские права? Сообщите нам.
Вуз: Предмет: Файл:
Постнов ДЭ после ИК.doc
Скачиваний:
0
Добавлен:
13.03.2024
Размер:
907.26 Кб
Скачать

Список литературы

1. Биленко М.В. Ишемические и реперфузионные повреждения ор­ганов (молекулярные механизмы, пути предупреждения и лече­ния). М.: Медицина, 1989. 368 с.

2. Болдырев А.А., Теердислое В.А. Молекулярная организация и ме­ханизм функционирования Na-насоса. Итоги науки и техники. Сер. Биофизика. М., 1978. Т. 10. 148 с.

3. Бъпиевский А.Ш., Терсенов О.А. Биохимия для врача. Екатерин­бург, 1994. С. 84.

4. Владимиров Г.Е. Влияние гипотермии, сочетанной с прекращением кровообращения, на обмен веществ в головном мозгу: Тез. докл. II конф. по биохимии нервной системы. Киев, 1957. С. 15-16.

5. Гастееа СВ., Райзе Т.Е., 5 Шаригина ЛМ. II Пат. физиол. 1986. №6. С. 9-11.

6 Иванов И.И., Зарембский Р.А., Короекин Б.Ф, и др. Введение в клиническую биохимию. Л.: Медицина, 1960. С. 311. Лабори А. 7 Метаболические и фармакологические основы нейро­физиологии. М.: Медицина, 1974. С. 168.

8 Лабори А. Регуляция обменных процессов. М.: Медицина, 1970. С. 363.

9 Никулин В.И. Интенсивность синтеза белков органов и тканей при гипотермии // Экспер. хирургия. 1957. № 1. С. 55-60.

  1. Семченко В.В., Степанов С.С., Алексеева F.B. Постаноксическая энцефалопатия. Омск: Омская областная типография, 1999.448 с.

  2. Слоан Т.Б. Успехи в решении проблемы защиты мозга // Вестник интенсивной терапии. ИТ в неврологии. 1993. Ш 1. С. 14-18.

  3. Тимофеев Н.Н. Гипобиоз и функциональная холодовая терморези- стентность // Физиология человека. 1986. Т. 12, № 1. С. 110-124.

  4. Тимофеев Н.Н., ПрокопьеваЛ.П. Нейрохимия гипобиоза и преде­ лы криорезистентности организма. М.: Медицина, 1997. 208 с.

  5. ШепердГ. Нейробиология/Пер. с англ. М.: Мир, 1987. Т. 1.С. 454.

  6. Adesuyi S.A., Cockrell C.S., Gamache D.A. et al. Lipoxygenase metabolism of arachidonic acid in brain // J. Neurochemistry. 1985. V. 45. P. 770-776.

  7. Aisen P. The transferrins // Iron in Biochemistry and Medicine. New York: Academic Press, 1980.

  8. Ames A., Wright R.L., Kowada M. 11 Amer. J. Path. 1968. V. 52. P. 437-453.

  9. Arrowsmith J.E., Harrison M.J.G., Newmann S.P. et al. Neuro- protection ofthe brain during cardiopulmonary bypass: a randomized trial of remacemide during coronary artery bypassin 177 patients // Stroke. 1998. V. 29. P. 2357-2362.

  10. Astup J. Energy-requiring cell functions in the ischemic brain // J. Neurosurgery. 1982. V. 56. P. 482-497.

  11. Becker K.J. Inflammation and acute stroke // Curr. Opin. Ncurol. 1998. V. 11. P. 45-49.

  12. BenvenisteH., DrejerJ., SchousboeA. et al. Elevations ofthe extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis // J. Neurochemistry. 1984. V. 43. P. 1369-1374.

  13. Bergstedt К., Ни B.R., Wieloch T. Postischemic changes in protein synthesis in the rat brain: effects of hypothermia // Exp. Brain Res. 1993. V. 95. P. 91-99.

  14. Berntman L, Welsh F.A., Harp J.R. Cerebral protective effect of low grade hypothermia //Anesthesiology. 1981. V. 55. P. 495^98.

  15. Bevan J.A. The human adrcnergic neurovascular mechanism // Fed. Proc. 1985. V. 44. P. 317-320.

  16. Bielenberg G.W., BurniolM., Rosen R. et al. Effects of nimodipine on infarct size and cerebral acidosis after middle cerebral artery occlusion in the rat // Stroke. 1990. V. 21. P. IV90-IV92.

  1. Bigelow W.G., Lindsay W., Greenwound W.F. Hypothermia. Its possible role in cardiac surgery: an investigation of factors governing survival in dogs at low temperatures // Ann. surgery. 1950. V.132, № 5. P. 849-866.

  2. Blauth C.I., Arnold J.V., Schulenberg W.E. et al. Cerebral microembolism during cardiopulmonary bypass // J. Thorac. Cardiovasc. Surg .1988. V. 95. P. 668.

  3. Blauth C.I., Cosgrove DM., Webb B. W et al. Atheroembolism from the ascending aorta: an emerging problem in cardiac surgery // J. Thorac. Cardiovasc. Surg. 1992. V. 103. P. 1104.

  4. BokeschP.M., KapuralM., Drummond-WebbJ. etal. Neuroprotective, anesthetic and cardiovascular effects ofthe NM0A antagonist, CNS 5161 A, in isoflurane-anesthetized lambs // Anesthesiology. 2000. V. 93. P. 202.

  5. Bond A., Lodge D., Hicks C.A. et al. NMDA receptor antagonism, but not AMPA receptor antagonism attenuates induced ischaemic tolerance in the gerbil hippocampus // Eur. J. Pharmacol. 1999. Sep. V. 10, № 380 (2-3). P. 91-99.

  6. Brewin E. G. Physiology of hypothermia // Int. Anesthesiol. Clin. 1964. V. 2: 803,

  7. Brooker R.F., Brown W.R., Moody DM. etal. Cardiotomy suction: a major source of brain lipid emboli during cardiopulmonary bypass // Ann. Thorac. Surg .1998. V. 65. P. 1651.

  8. Bryant P.E. Enzymatic restriction of mammalian cell DNA: evidence for double-strand breaks as potentially lethal lesions // International J. Radiation Research. 1985. V. 48. P. 55-60.

  9. Buerke M., Weyrich A.S., Zheng Z. et al. Sialyl Lewisxx-containing oligosaccharide attenuates myocardial reperfusion injury in cats // J. Clin. Invest. 1994. V. 93. P. 1140-1148.

  10. Bull D.A., Neumayer L.A., Hunter G.C. Risk factors for stroke in patients undergoing coronary artery bypass grafting // Cardiovasc. Surg. 1993. V. l.P. 182-185.

  11. Burrows F.A., Hillier S.C., McLeod M.E. Anterior fontanel pressure and visual evoked potentials in neonates and infants undergoing profound hypothermic circulatory arrest // Anesthesiology. 1990. V. 73. P. 632-636.

  12. Busija S.W. Sympathetic nerves reduce cerebral blood flow during hypoxia in awake rabbits // Am. J. Physiol. 1984. V. 247. P. 446-451.

  13. Busto R., Dietrich W.D., Globus M.Y. Small differences in the intra- ischemic brain temperature critically determine the extent of ischemic neuronal injury // J. Cerebral Blood Flow Metabolism. 1987. V. 7. P. 729-738.

  14. Busto R., Globus M, Bietrich W.D. et al. Effect of mild hypothermia on ischemia-induced release of neurotransmittcrs and free fatty acids in rat brain // Stroke. 1989. V. 20. P. 904.

  15. Cameron D. Initiation of white cell activation during cardiopulmonary bypass: cytokines and receptors // J. Cardiovasc. Pharmacol. 1996. V. 27. P. S1-S5.

  16. Cardell M., Boris-Moller Т., Wieloch T. Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinasc С in the rat striatum // J. Neurochemistry. 1991. V. 57. P. 1814-1817.

  17. CavarocchiN.C., EnglandM.D., O'Brien J.F. Superoxide generation during cardiopulmonary bypass: is there a role for vitamin E? // J. Surg. Res. 1986. 40. P. 519-527.

  18. Cernaianu A.C., Vassilidze T.V., Flum DR. Predictors of stroke after cardiac surgery // J. Card. Surg. 1995. V. 10. P. 334-339.

  19. Cheng M.A., Theard M.A., Tempelhoff R. Intravenous agents and intraoperative neuroprotection. Beyond barbiturates // Crit. Care Clin. 1997. V. 13. P. 185-199.

  20. Chenoweth D.E., Cooper S. W., Hugh Т.Е. et al. Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins // N. Engl. J. Med. 1981. V. 304. P. 497.

  21. Choi D. W. Calcium: still center-stage in hypoxic-ischemic neuronal death //Trends Neurosc. 1995. V. 18. P. 58.

  22. ChoppM., Li Y, Jiang N. et al. Antibodies against adhesion molecules reduce apoptosis after transient middle cerebral artery occlusion in rat brain // J. Cereb. Blood. Flow. Metab. 1996. V. 16. P. 578-584.

  23. Chow H.S., Lynch J.J., Rose K., Choi D. W. Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA // Brain Res. 1994. 639. P. 102-108.

  24. Churn S.B., Toft W.C., Billings ley M.S. et al. Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin- dependent protein kinase II in gerbils // Stroke. 1990. V. 21. P. 1715-1721.

  25. Cook D.J., Oliver W.C. Jr., Orszulak T.A. et al. Cardiopulmonary bypass temperature, hematocrit, and cerebral oxygen delivery in humans // Ann. Thorac. Surg. 1995. V. 60. P. 1671-1677.

  1. CosgroveDM., Heric В., Lytle B. W. Aprotinin therapy for reoperative myocardial revascularization: a placebo-controlled study // Ann. Thorac. Surg. 1992. V. 54. P. 1031-1036.

  2. Craver J.M., Puskas J.D., Weintraub W.W. 601 octogenarians undergoing cardiac surgery: outcome and comparison with younger age groups // Ann. Thorac. Surg. 1999. V. 67. P. 1104-1110.

  3. Croughwell N.D., Reves J.G., White W.D. et al. Cardiopulmonary bypass time does not affect cerebral blood flow // Ann. Thorac. Surg. 1998. V. 65. P. 1226-1230.

  4. De Marchena O., Guarnieri M., Me Khann G. II J. Neurochemistry. 1974. V. 22. P. 239-270.

  5. del Zoppo G.J. Investigational use of tPA in acute stroke // Ann. Emerg. Med. 1988. V. 17 (11). P. 1196-1201.

  6. Freeman B.A., Crapo J.D. Biology of disease. Free radicals and tissue injury // Laboratory Investigations. 1982. V. 47. P. 412-416.

  7. del Zoppo G.J. Microvascular responses to cerebral ischemia/ inflammation // Ann. N. У. Acad. Sci. 1997. V. 823. P. 132-147.

  8. Demopoulos H.B., Flamm E.S., Pietronigro D.D. II Acta physiol. Scand. 1980.492. P. 91-119.

  9. Filers K, Bidder P.E. Hypothermia and isoflurane similary inhibit glutamate release evoked by chemical anoxia in rat cortical brain slices // Anesthesiology. 1996. V. 85, № 3. P. 600-607.

  10. Elsass P., Henriksen L. Acute cerebral dysfunction after open-heart surgery: a reaction-time study // Scand. J. Thorac. Cardiovasc. Surg. 1984. V. 18. P. 161.

  11. Engelman R.M., Rousou J.A., Flack J.E. et al Influence of steroids on complement and cytokine generation after cardiopulmonary bypass // Ann. Thorac. Surg. 1995. V. 60. P. 801.

  12. Erdo S.L., Schafer M. Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate // Eur. J. Pharmacol. 1991. V. 198. P. 215.

  13. Erecinska M, Silver LA. ATP and brain function // J. Cerebral Blood Flow Metabolism. 1989. V. 9. P. 2-19.

  14. Faraci F.M., Heistad D.D. Regulation of cerebral blood vessels by humoral and endjthelium-dependent mechanisms. Update on humoral regulation of vascular tone // Hypertension. 1991. V. 17. P. 917-922.

  1. Folbergrova J., Kiyota Y., PahlmarkK. Does ischemia with reperfiision lead to oxidative damage to proteins in the brain? // J. Cereb. Blood Flow Metab. 1993. V. 13. P. 145-152.

  2. Forsman M., Olsnes B.T., Semb G. et al. Effects of nimodipine on cerebral blood flow and neuropsychological outcome after cardiac surgery // Br. J. Anaesth. 1990. V. 65. P. 514-520.

  3. Freeman B.A., Crapo J.D. Biology of disease. Free radicals and tissue injury // Laboratory Investigations. 1982. V. 47. P. 412-416.

  4. Friedman M., Johnson R. G., WangS. Y. et al. Pulmonary microvascular responses to protamine and histamine // J. Thorac. Cardiovasc. Surg. 1994. V. 108. P. 1092-1099.

  5. Fujie W., Kirino Т., Tomukai N. et al. Progressive shrinkage of the thalamus following middle cerebral artery occlusion in rats // Stroke. 1990. V. 21. P. 1485.

  6. Galli K.K., Zimmerman R.A., Jarvik G.P. et al. Pcriventricular leukomalacia is common after neonatal cardiac surgery // J. Thorac. Cardiovasc. Surg. 2004. V. 127. P. 692-704.

  7. Garthwaite J., Garthwaite G., Palmer R.M. et al. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices // Eur. J. Pharmacol. 1989." V. 172. P. 413.

  8. Garthwaite J. Nitric oxide signalling in the nervous system // Neurosciences. 1993. V. 5. P. 171.

  9. Gaudet R.J., Alam I., Levine L. Accumulation of cyclooxygenase products of arachidonic acid metabolism in gerbil brain during reperfusion after bilateral common carotid artery occlusion // J. Neurochemistry. 1980. V. 35. P. 653-658.

  10. GaynorJ. W. Perivcntricular leukomalacia following neonatal and infant cardiac surgery // Semin Thorac. Cardiovasc. Surg. (Pediatr. Card. Surg. Ann.). 2004. V. 7. P. 133-140.

  11. Gelmers H.J., Hennerici M. Effect of nimodipine on acute ischemic stroke. Pooled results from five randomized trials // Stroke. 1990. V 21. P. IV81-IV84.

  12. Gillinov A.M., Redmond J.M., ZehrK.J. et al. Inhibition of neutrophil adhesion during cardiopulmonary bypass // Ann. Thorac. Surg. 1994. V. 57. P. 126-133.

  13. Granger D.N., Kubes P. The microcirculation and inflammation: modulation of leukocytc-endothelial cell adhesion // J. Leukoc. Biol. 1994. V. 55. P. 662-675.

  1. Greely W.J., Kern F.H., Ungerleider R.M. The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants and children // J. Thorac. Cardiovasc. Surg. 1991. V. 101. P. 783-794.

  2. Guitieerrez G. Cellular energy metabolism during hypoxia // Critical Care Medicine. 1991. V. 19. P. 619-626.

  3. Gunvitz J.H., Bohn R.L., Glynn R.J. et al. Glucocorticoids and the risk for initiation of hypoglycaemic therapy // Arch. Intern. Med. 1994. V. 154. P. 97.

  4. Hagberg J., Andersson P., Kjellmer I. Extracellular overflow of glutamate, aspartate, GABA, and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia //Neuroscience Letters. 1987. V. 78. P. 311-317.

  5. Hagberg J., Andersson P., LacarewiczJ. et al. Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia // J. Neurochemistry. 1987. V. 49. P. 227-231.

  6. Hall E.D. Inhibition of lipid peroxidation in central nervous system trauma and ischemia // J. Neurol. Sci. 1995. V. 134. P. 79-83.

  7. Hall R.I., Smith M.S., Rocker G. The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations // Anesth. Analg. 1997. V. 85. P. 766-782.

  8. HalliwellB., Gutteridge J.M.C. //Trends. Neurosci. 1985. V. 8. № 1. P. 22-26.

  9. Hammeke T.A., Hastings J.E.Neuropsychologic alterations after cardiac operations // J. Thorac. Cardiovasc. Surg. 1988. V. 96. P. 326-331.

  10. Hansen A.J. Effect of anoxia on ion distribution in the brain // Physiology Reviews. 1985. V. 65. P. 101-148.

  11. Hara H, Nagasawa H., Kogure K. Nimodipine prevents postischemic brain damage in the early phase of focal cerebral ischemia // Stroke. 1990. V. 21. P. IV102-IV104.

  12. Hartley A., Stone J.M., Heron C. et al. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease // J. Neurochem. 1994. V. 63. P. 1987.

  13. Hasegawa K., Yoshioka H., Sawada Т., Nishikawa H Direct measurement of free radicals in the neonetal mouse brain subjected to

hypoxia: an electron spin resonance spectroscopic study // Brain Res. 1993. V. 607. P. 161-166.

  1. HerlitzJ., Brandrup-Wognsen G., HaglidM. Mortality and morbidity during a period of 2 years after coronary artery bypass surgery in patients with and without a history of hypertension // J. Hypertens. 1996. V. 14. P. 309-314.

  2. Inal M., Alatas Q., Kural Т., Sevin B. Oxygen free radicals in erythrocytes during open heart operations // J. Cardiovasc. Surg. 1994. V. 35. P. 146-150.

  3. Ito H., Watanabe Y, Isshiki A., Uchino H. Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABA receptors // Acta. Anaesthesiol. Scand. 1999. V. 43 (2). P. 153-162.

  4. JingJ.,AitkenP.G., Somjen G.G. Role of calcium channels in spreading depression in rat hippocampal slices//Brain Res. 1993. V. 604, № 1-2. P. 251-259.

  5. Johnston W.E., Vinten-Johansen J., DeWitt D.S. et al. Cerebral perfusion during canine hypothermic cardiopuimonary bypass: effect of arterial carbon dioxide tension // Ann. Thorac. Surg. 1993. V. 52. P. 479^89.

  6. Kaibara Т., Sutherland G.R., Colbourne F, Tyson R.L. Hypothermia: depression of tricarboxylic acid cycle flux and evidence for pentose phosphate shunt upregulation // J. Neurosurg. 1999. V. 90 (2). P. 339-347.

  7. Kanehisa M.I., Tsong T.Y Cluster model of Iipid phase transitions with application of passive permeation of molecules and structure relaxations of Iipid bilayers // J. Amer. Chem. Soc. 1978. V. 100, № 2. P. 424-432.

  8. Karibe H. et al. Mild intraischemic hypothermia supresses consumption of endogenous antioxydants after temporary focal ischemia in rats // Brain Res. 1994. V. 649. P. 12-18.

  9. Kawamura Т., Inada K., Okada H. et al. Methylprednisolone inhibits increase of interleukin 8 and 6 during open heart surgery // Can. J. Anaesth. 1995. V. 42. P. 399.

  10. KernF.K, Ungerleider R.M., QuillTJ. etal. Cerebral blood flow response to changes in PaCO2 during hypothermic cardiopuimonary bypass in children // J. Thorac. Cardiovasc. Surg. 1991. V. 101. P. 618-622.

  11. Khabar K.S.A., El Barbary M.A., Khouqeer F. et al. Circulating endotoxin and cytokines after cardiopuimonary bypass: differentialcorrelation with duration of bypass and systemic inflammatory response/multiple organ dysfunction syndromes // Clin. Immunol. Immunopathol. 1997. V. 85. P. 97.

  1. Kirino Т., TamuraA., SanoK. A reversible type of neuronal injury following ischemia in the gerbil hippocampus // Stroke. 1986. V. 37. P. 455^59.

  2. Kirsch J.R., Traystman R.J., Hum P.D. Anesthetics and cerebroprote- ction: experimental aspects // Int. Anesthesiol. Clin. 1996. V. 34. P. 73.

  3. Korthuis R.J., Anderson D.C., Granger D.N. Role of neutrophil- endothclial cell adhesion in inflammatory disorders // J. Crit. Care. 1994. V. 9. P. 47-71.

  4. Kristian Т., Katsura K., Gido G., Siesjo B.K, The influence of pH on cellular calcium influx during ischemia // Brain Res. 1994. V. 641, № 2. P. 295-302.

  5. Laptook A.R., Corbett R.J., Sterett R. et al. Quantitative relationship between brain temperature and energy utilization rate measured in vivo using 31P and 1H magnetic resonance spectroscopy // Pediatr. Res. 1995. V. 38, № 6. P. 919-925.

  6. Lazenby W.D., Wilson K., Zelano J.A. et al Effects of temperature and flow rate on regional blood flow and metabolism during cardiopuimonary bypass // Ann. Thorac. Surg. 1992. V. 53. P. 957.

  7. Lee A.G. Lipid phase transitions and phase diagrams // J. Biochem. Biophys. Acta. 1977. V. 472, № 2. P. 237-281.

  8. Legauli C, Furberg C.D., Wagenknecht L.E. et al. Nimodipine neuroprotection in cardiac valve replacement: report of an early terminated trial // Stroke. 1996. V. 27. P. 593-598.

  9. Lehninger A.L. Proton and electric charge translocation in mitochondrial energy transduction // Adv. Exp. Med. Biol. 1982. V. 148. P. 171-186.

  10. Lillehei C.W. Historical development of cardiopuimonary bypass // Gravlee G.P., Davis R.F., Utley J.R. Cardiopuimonary bypass: principles and practice. Baltimore: Williams & Wilkins, 1993.

  11. Upton S.A., Wang Y.F NO-related species can protect from focal cerebral ischemia/reperfusion // Krieglstein J., ed. Pharmacology of cerebral ischemia. Stuttgart, Germany: Medpharm Scientific Publishers, 1996. P. 186.

  12. Litt L., Espanol M.T., Hasegawa K. et al. NOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices // Anesthesiology. 1999. V. 90. P. 1392.

  1. LlinasR.,BarbutD., CapIanL.R. Neurologic complications of cardiac surgery // Prog. Cardiovasc. Dis. 2000. V. 43. P. 101-112.

  2. MacKnight A.D.C., Leaf A. Regulation of cell volume // Physiology Reviews. 1977. V. 57. P. 510-569.

  3. Martin C.E., Hiramotsu K., Kitajama Y et al. Fatty acid desaturase regulation of membrane fluidity in acclimation of Tetrahymena cells // Biochemistry. 1976. V. 15, № 24. P. 5218-5228.

  4. McKhann G.M., Goldbowugh M.A., Borowicz LM. jr. Predictors of stroke risk in coronary artery bypass patients // Ann. Thorac. Surg. 1997. V. 63. P. 516-521.

  5. Meldrum B.S. Cellul

  1. r and molecular mechanisms of ischemic brain damage: the role of nitric oxide in ischemic damage // Adv. Neurol. 1996. V. 71. P. 355.

  2. Michenf elder J.D. The hypothermic brain // Anesthesia and the Brain. Churchill Livingstone, New York, 1988.

  3. Michenf elder J.D., Milde J.H., Sundt T.M.jr. Cerebral protection by barbiturate anesthesia. Use after middle cerebral artery occlusion in Java monkeys // Arch. Neurol. 1976. V. 33. P. 345-350.

  4. Michenf elder J.D. A valid demonstration of barbiturate-induced brain protection in manat last // Anesthesiology. 1986. V. 64. P. 140-142.

  5. Mies G., Paschen IV. Regional changes of blood flow, glucose and ATP content determined on brain section during a single passage of spreading depression in rat brain cortex // Experimental Neurology. 1984. V. 84. P. 249-258.

  6. Morikawa E., Zhang S.M., Seko Y et al. Treatment of focal cerebral ischemia with synthetic oligopeptide corresponding to lectin domain of selectin // Stroke. 1996. V. 27. P. 951-955; discussion P. 956.

  7. Moskowitz M.A., Kiwak K.J., Hekimian K. Synthesis of compounds with properties of leukotriens C4 and D4 in gerbil brains after ischemia and reperfusion // Science. 1984. V. 224. P. 886-889.

  8. Moskowitz M.A., Meyer E., Wurtman R.J. et al. Attenuation of catecholamine antagonists of the hypothermia that follows cerebral infarction in the gerbil // Life Sciences. 1975. V. 17. P. 597-602.

  9. Murkin J.M., Martzke J.S., Buchan A.M. et al. A randomized study of the influence of perfusion technique and pH management strategy in 316 patients undergoing coronary artery bypass surgery: (part 2) neurological and cognitive outcomes // J. Thorac. Cardiovasc. Surg. 1995. V. 110. P. 349-362.

  1. Murohara Т., Buerke M., Lefer A.M. Polymorphonuclear leukocyte- induced vasocontraction and endothelial dysfunction. Role of selectins // Arterioscler. Thromb. 1994. V. 14. P. 1509-1519.

  2. Mutch W.A., Hansen A.J. Extracellular pH changes during spreading depression and cerebral ischemia: mechanisms of brain pH regulation // Cerebral Blood Flow Metabolism. 1984. V. 4. P. 17-27.

  3. Mutch W.A., RynerL.N., KozlowskiP. Cerebral hypoxia during cardio- pulmonary bypass: a magnetic resonance imaging study // Ann. Thorac. Surg. 1997. V. 64. P. 695-701.

  4. Nakai M., Tamaki K., Maeda M. Sympathetic and metabolic mechanisms of the cerebrovasomotor function of the caudal ventro- lateral medulla in rats // Neuroscience. 1992. V. 50. P. 655-662.

  5. NandateK., VuylstekeA., CrosbieA.E. et al Cerebrovascular cytokine responses during coronary artery bypass surgery: specific production of interleukin-8 and its attenuation by hypothermic cardiopulmonary bypass // Anesth. Analg. 1999. V. 894. P. 823-828.

  6. Navas J.P., Anderson W., Marsh J.D. Hypothermia increaeses calcium content of hypoxic myocytes // American J. Physiology. 1990. V. 259. P. 333-339.

  7. Newman M.F., Murkin J.M., Roach G. et al. Cerebral physiologic effects of burst suppression doses of propofol during nonpulsatilc cardiopulmonary bypass. CNS Subgroup of McSPI // Anesth. Analg. 1995. V. 81. P. 452-457.

  8. NisbetH.LA. Acid base Disturbances in hypothermia // Int. Anesthesiol. Ciin. 1964. V. 2. P. 829.

  9. Norsdtrom C.H., SiesjoB.K. Influence ofphenobarbital on changes in the metabolites of the energy reserve of the cerebral cortex following complete ischemia // Acta Physiologica Scandinavica. 1978. V. 104. P. 271-280.

  10. Norwood W.L., Norwood C.R., Ingwall J.S. et al. Hypothermic circulatory arrest 31-Phosphorous nuclear magnetic resonance of isolated perfused neonatal rat brain // J. Thorac. Cardiovasc. Surg. 1979. V. 78. P. 823.

  11. NussmeierN, Arlund C, SlogoffS. Neuropsychiatric complications after cardiopulmonary bypass: cerebral protection by a barbiturate // Anesthesiology. 1986. V. 64. P. 165-170.

  12. NussmeierN.A. Adverse neurologic events: risks of intracardiac versus extracardiac surgery // J. Cardiothorac. Vase. Anesth. 1996. V. 10 P. 31-37.

  13. Ooboshi H., Ibayashi S., Takano K. et al. Hypothermia inhibits ischemia-induced efflux of amino acids and neuronal damage in the hippocampus of aged rats // Brain Res. 2000. V. 24, № 884. P. 23-30.

  14. Owen O.E., Morgan A.P., Kemp KG. et al. Brain metabolism during fasting // J. Clin. Invest. 1967. V. 46 (10). P. 1589-1595.

  15. Pang 2., Geddes J.W. Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis // J. Neurosci. 1997. V. 17, № 9. P. 3064-3073.

  16. Pantoni L, Sarti C, lnzitari D. Cytokines and cell adhesion molecules in cerebral ischemia: experimental bases and therapeutic perspectives //Arterioscler. Thromb. Vase. Biol. 1998. V. 18. P. 503-513.

  17. Patel P.M., Drummond J.C., Cole D.J. Isoflurane reduces ischemia- induced glutamate release in rats subjected to forebrain ischemia // Anesthesiology. 1995. V. 82. P. 996.

  18. Pearce W.J., Dalecy L.G. Hemorrhage induced cerebral vasocon- striction in dogs // Sroke. 1980. V. 11. P. 190-197.

  19. PkkardJ.D., Murray G.D., lllingworth R. Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial // В. М. J. 1989. V. 298. P. 636-642.

  20. Poggetti R.S., Moore E.E., Moore F.A. et al. Liver injury is a reversible neutrophil-mediated event following gut ischemia// Arch. Surg. 1992. V. 127. P. 175-179.

  21. Prough D.S., Rogers А.Т., Stump D.A. et al Cerebral blood flow decreases with time whereas cerebral oxygen consumption remains stable during hypothermic cardiopulmonary bypass in humans // Anesth. Analg. 1991. V. 72. P. 161-168.

  22. Radford I.R. The level of induced DNA double strand breakage correlates with cell killing after X-irradiation // International J. Radiation Biology. 1985. V. 48. P. 45-54.

  23. Reasoner D.K., Hindman B.J., Dexter F. et al Doxycycline reduces early neurologic impairment after cerebral arterial air embolism in the rabbit//Anesthesiology. 1997. V. 87. P. 569.

  24. Rebeky I. Hypothermic cardiopulmonary bypass in neonates infants and young children. Butter Worth-heinemann, 1994. P. 50-66.

  25. ReplogleR-L, GazzaniaA.B., GrossR.E. Use of corticosteroids during cardiopulmonary bypass: possible lysosome stabilization // Circulation. 1966. V. 33 (Suppl. I). P. 1-86.

  1. Rich T.L., Langer G.A. Calcium depletion in rabbit myocardium: calcium paradox protection by hypothermia and cation substitution // Circulation Research. 1982. V. 51. P. 131-141.

  2. Poggetti R.S., Moore E.E., Moore F.A. et al. Liver injury is a reversible neutrophil-mediated event following gut ischemia// Arch. Surg. 1992. V. 127. P. 175-179.

  3. Rittenhouse E.A., MohriH., Mevendino K.A. Studies of carbohydrate metabolism and serum electrolytes during surface-induced deep hypothermia with prolonged circulatory occlusion // Surgery. 1970. V. 67. P. 995.

  4. Roach G. W. Pro prevention of neurologic dysfunction associated with cardiac surgery requires pharmacologic brain protection // J. Cardiothorac. Vase. Anesth. 1997. V. II. P. 793-795.

  5. Roach G.W., Kanchuger M, Mangano CM. et al. Adverse cerebral outcomes after coronary bypass surgery: Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators // N. Engl. J. Med. 1996. V. 335. P. 1857.

  6. Roach G. W., Newman M.F., Murkin J.M. et al. The Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Ineffectiveness of burst suppression therapy in mitigating perioperative cerebro- vascular dysfunction // Anesthesiology. 1999. V. 90. P. 1255.

  7. Rogers A. Con: preventing stroke after cardiopulmonary bypass does not require pharmacologic neuroprotection // J. Cardiothorac. Vase. Anesth. 1997. V. II. P. 796-800.

  8. Rogers А.Т., Stump D.A., Gravlee G.P. et al. Response of cerebral blood flow to phenylephrine infusion during hypothermic cardiopulmo­ nary bypass: influence ofPaCO, management//Anesthesiology. 1988. V. 69. P. 547-551.

  9. Rogers M.C., Kirsch J.R. Current concepts in brain resuscitation // JAMA. 1989. V. 261. P. 3143.

  10. Rosenberg A.A. II Pediat. Res. 1986. V. 20, № 8. P. 778-782.

  11. Rossomoff H.L., Holaday D.A. Cerebral blood flow and cerebral oxygen consumption during hypothermia// Amer. J. Physiol. 1954. V. 179. P. 85.

  12. Rothman S.M., Olney J.W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage // Ann. Neurology. 1986. V. 19. P. 105-111.

  1. Roytblat L, Roy-Shapira A., Greenberg L. et al. Ketamine and IL-6 response after СРВ // Anesth. Analg. 1998. V. 87. P. 266.

  2. SadoshimaS., FujiiK., KusudaK. Importance of bilateral sympathetic innevation on cerebral blood flow autoregulation in the thalamus // Brain Res. 1987. V. 413. P. 297-301.

  3. Said S., Rosenbhim W.I., Povlishock J.T. et al. Correlations between morphological changes in platelet aggregates and underlying endothelial damage in cerebral microcirculation of mice // Stroke. 1993. V. 24. P. 1968-1976.

  4. SchmelingDJ,, CatyM.G., Oldham KT. et al. Evidence for neutrophil- related acute lung injury after intestinal ischemia-reperfusion // Surgery.

1989. V. 106. P. 195-202.

  1. Schmidt-Kastner R., Freund T.F. Selective vulnerability of the hyppocampus in brain ischemia // J. Neurosci. 1991. V. 40. P. 599-636.

  2. Schubert S., Stoltenburg-Didinger G., Wehsack A. et al. Large-dose pretreatment with methylprednisolone fails to attenuate neuronal injury after deep hypothermic circulatory arrest in a neonatal piglet mode! //Anesth. Analg. 2005. V. 101 (5). P. 1311-1318.

  3. Seccombe J.F, Schaff H. V. Coronary artery endothelial function after myocardial ischemia and reperfusion // Ann. Thorac. Surg. 1995. V. 60. P. 778-788.

  4. Seifel Nasr M., Peruche В., Rossberg C. et al. Neuroprotective effect of memantine demonstrated in vivo and in vitro // Eur. J. Pharmacol.

1990. V. 185. P. 19.

  1. Severinghaus J.W., Lassen N. Step hypocapnia to separate arterial from tissue PCO2 in the regulation of cerebral blood flow // Circ. Res. 1967. V. 20. P. 272-278.

  2. Shafique Т., Johnson R.G., Dai H.B. et al. Altered pulmonary microvascular reactivity after total cardiopulmonary bypass // J. Thorac. Cardiovasc. Surg. 1993. V. 106. P. 479^86.

  3. Shaw P.J., Bates D., Cartlidge N.F. et al. Neurologic and neuropsychological morbidity following major surgery: comparison of coronary artery bypass and peripheral vascular surgery // Stroke. 1987. V. 18. P. 700.

  4. Shimizu H., Graham S.H., Chang L.H. Relationship between extracellular neurotransmitter amino acids and energy metabolism during cerebral ischemia in rats monitored by microdialysis and in

vivo magnetic resonance spectroscopy // Brain Res. 1993. V. 605, № l.P. 33^12.

  1. Shinozuka T, Nemoto E.M., Winter P.M. Mechanisms of cerebrovascular O2 sensivity form hyperoxia to moderate hypoxia in the rat // J. Cereb. Flow Metab. 1993. V. 9. P. 187-195.

  2. Shum-Tim £>., Tchervenkov C.I., Jamal A.M. et al. Systemic steroid pretreatment improves cerebral protection after circulatory arrest // Ann. Thorac. Surg. 2001. V. 72 (5). P. 1465-1471.

  3. Shum-TimD., Tchervenkov C.I., Laliberte E. etal. Timing of steroid treatment is important for cerebral protection during cardiopulmonary bypass and circulatory arrest: minimal protection of pump prime methylprednisolone // Eur. J. Cardiothorac. Surg. 2003. V. 24 (1). P. 125-132.

  4. Siesjo B.K., Siesjo P. Mechanisms of secondary brain injury // Eur. J. Anaesthesiol. 1996. V. 13. P. 247.

  5. SlogoffS., Girgis K.Z., Keats A.S. Etiologic factors in neuropsychiatric complications associated with cardiopulmonary bypass // Anesth. Analg. 1982. V. 61. P. 903-911.

  6. Smith P.K., Muhlbaier L.H. Aprotinin: safe and effective only with full-dose regimen // Ann. Thorac. Surg. 1996. V. 62. P. 1575-1577.

  7. Smith P.L.C., Treasure Т., Newman S.P. Cerebral consequences of cardiopulmonary bypass // Lancet. 1986. V. I. P. 823-825.

  8. Southard J.H. Temperature effects and cooling // Zeienock G.B., D'Alecy L.G., Fantone J.C. etal. Clinical Ischemic Syndromes. St. Louis. CV Mosby, 1990. P. 303-325.

  9. Spandou E., Karkavelas G, Soubasi V. et al. Effect of ketamine on hypoxic-ischemic brain damage in newborn rats // Brain Res. 1999. V. 819(1-2). P. 1-7.

  10. Steiner M.G., Babbs C.F. Hydroxyl radical generation by postishecmic rat kidney slices in vitro // Free Radic. Biol. Med. 1990. V. 9. P. 67-77.

  11. Sturaitis U.K., Moore L.E., Kirsch J.R. A cholinergic agonist induces cerebral hyperemia in isoflurane- but not pentobarbital-anesthetized dogs // Anesth. Analg. 1994. 78. P. 876-883.

  12. Swain J.A., McDonald T.J., Balaban R.S., Robbins R.C. Metabolism of the heart and brain during hypothermic cardiopulmonary bypass //Ann. Thorac. Surg. 1991. V. 151. P. 105-109.

  1. Tabardel Y., Duchateau J., Schmatz D. et al. Corticosteroids increase blood interleukin 10 levels during cardiopulmonary bypass in men // Surgery. 1996. V. 119. P. 76.

  2. Tang W., Sun G.Y. Effects of ischemia on free fatty acids and diacylglycerols in developing rat brain // J. Development Neuroscience. 1985. V. 3. P. 51-56.

  3. TardiffB.E., Newman M.F., Saunders A.M. et al. Preliminary report of a genetic basis for cognitive decline after cardiac operations // Ann. Thorac. Surg. 1997. V. 64. P. 715.

  4. Teoh K.H.T., Bradley C.A., Gauldie J. et al. Steroid inhibition of cytokine-mediatcd vasodilation after warm heart surgery // Circulation. 1995. V. 92 (Suppl. II). P. 11-347.

  5. Tsui S.S., Kirshbom P.M., Davies M.J. et al. Nitric oxide production affects cerebral perfusion and metabolism after deep hypothermic circulatory arrest // Ann. Thorac. Surg. 1996. V. 61. P. 1699-1707.

  6. Tullis R.H., Rubin H. Calcium protects DNAsel from proteinase К: а new method for the removal of spin-trapped radicals radicals in aqueous solutions of pyrimidine nucleosides and nucleotides // International J. Radiation Biology. 1982. V. 41. P. 241.

  7. Tuman K.J., McCarthy R.J., Najafi H. et al. Differential effects of advanced age on neurologic and cardiac risks of coronary artery operations // J. Thorac. Cardiovasc. Surg. 1992. V. 104. P. 1510.

  8. Turunen J.P., Majuri M.L., Seppo A. et al. De novo expression of endothelial sialyl Lewis (a) and sialyl Lewis (x) during cardiac transplant rejection: superior capacity of a tetravalent sialyl Lewis(x) oligosaccharide in inhibiting L-select-indepcndent lymphocyte adhesion //J. Exp. Med. 1995. V. 182. P. 1133-1141.

  9. van der Linden J., Casimir-Ahn H, When do cerebral emboli appear during open heart operations? A transcranial Doppler study // Ann. Thorac. Surg. 1991. V. 51. P. 237-241.

  10. Venn G.E., Sherry K., Klinger L. Cerebral blood flow during cardiopulmonary bypass // Eur. J. Cardiothorac. Surg. 1988. V. 2. P. 360-363.

  11. Wahl M., Schilling L. Regulation of cerebral blood flow - a brief review // Acta Neurochirurgia (Suppl.). 1993. V. 59. P. 3-10.

  12. Wan S., LeClerc J.L., Vincent J.L. Inflammatory response to cardiopulmonary bypass // Chest. 1997. V. 112. P. 676.

  1. WardJ.K, Blakely W.F., Joner E.I. Mammalian cells are not linked by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide // Radiation Research. 3985. V. 103. P. 383-392.

  2. Wieloch Т., Harris R.J., Symon L. et al. Influence of severe hypoglycemia on brain extracellular calcium and potassium activities, energy, and phospholipids metabolism // J. Neurochemistry. 1984. V. 43. P. 160-168.

  3. Xie Y.X., DenglerK., Lacharias E. et al. Effect of the sodium channel blockcr tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia // Brain Res. 1994. V. 652, № 2. P. 216-224.

  4. Zaidan J.R., Klochany A., Martin W.M. et al. Effect of thiopental on neurologic outcome following coronary artery bypass grafting // Anesthesiology. 1991. V. 74. P. 406-411.