- •Content
- •Сontent module 11: blood system physiology
- •Lesson 31
- •Blood physical-chemical features investigation
- •2. Study aims:
- •3.1.Basic knowledge, skills, experiences, necessary for study the topic:
- •3.2.Topic content
- •Introduction
- •Variations in plasma protein level
- •Increase in all fractions
- •Materials for auditory self-work.
- •Task 1. To get acquainted with blood taking technology for analysis performance.
- •Task 2. To determine erythrocytes osmotic resistance.
- •Task 3. Velocity sedimentation rate (vsr) determining.
- •2. Literature recommended:
- •Materials for self-control:
- •Lesson 32
- •Erythrocytes number and hemoglobin concentration investigation
- •Introduction and normal value
- •Variations in number of red blood cells
- •Variations in size of red blood cells
- •Variations in shape of red blood cells
- •In postnatal life and in adults
- •2. Hormones:
- •1. Vitamin b12 (Cyanocobalamin)
- •2. Intrinsic Factor of Castle
- •3. Folic Acid
- •Neural-humoral erythropoiesis regulation
- •Erythropoiesis inhibitors
- •Iron metabolism
- •Task 1. To determine erythrocytes amount in blood.
- •Task 2. Hemoglobin content determining in blood.
- •Task 3. To estimate blood color index.
- •Lesson 33
- •Blood groups belonging investigation
- •2. Study aims:
- •Table 2. The blood groups with their genotypes and their constituent agglutinogens and agglutinins
- •Materials for auditory self-work
- •4.1. List of study practical tasks necessary to perform at the practical class.
- •Task 2. To determine rhesus-factor while express-method usage.
- •Task 3. To perform probe on individual compatibility.
- •Literature recommended:
- •Materials for self-control:
- •Lesson 34
- •Leucocytes number, leucocytic formule investigation
- •2. Study aims:
- •Variations in the count of white blood cells
- •Innate immunity
- •Introduction
- •Immunization
- •1. Interleukins
- •2. Interferons
- •Acquired immunodeficiency syndrome (aids)
- •Differentiated leucocytes ageing changing in children
- •Leucocytes functions significance in dentistry
- •Materials for auditory self-work
- •Task 1 Leucocytes estimation in Goryaev’s chamber
- •5. Literature recommended:
- •Lesson 35
- •Platelets and vascular-platelet hemostasis investigation
- •1. The topic studied actuality.
- •Complications after teeth extraction in patients with microcirculative hemostasis disorders
- •2. Study aims:
- •Error: Reference source not found
- •4 Forms of platelets:
- •Hemostasis
- •Platelet plug formation
- •Vascular-platelet hemostasis
- •Vessels temporary spasm:
- •Vessels injury
- •Adhesion
- •Platelets
- •Releasing reaction
- •4. Materials for auditory self-work
- •4.1. List of study practical tasks necessary to perform at the practical class.
- •Task 1. Bleeding duration determining (by Duke).
- •Task 2. Aggregatogram analysis principle.
- •5. Literature recommended:
- •6. Materials for self-control:
- •Lesson 36
- •Blood coagulation investigation
- •Physiological bases of measurements at prolonged bleeding after tooth extraction
- •Physiological basement of patients preparation to tooth extraction at blood diseases
- •Complications occurring after tooth extraction in patients with blood coagulation disorders
- •2. Study aims:
- •3.1.Basic knowledge, skills, experiences, necessary for study the topic:
- •Topic content
- •Plasma blood coagulation factors
- •Materials for auditory self-work
- •Task 1. To study thromboelastogram.
- •5. Literature recommended:
- •6. Materials for self-control:
- •Lesson 37
- •Differentiated coagulogram. Disseminated intravascular coagulation (dic) syndrome
- •2. Study aims:
- •3.1.Basic knowledge, skills, experiences, necessary for study the topic:
- •Topic content
- •Main pathological processes and influences accompanied by dic-syndrome development (dic ethiology)
- •Dic types:
- •4. Materials for auditory self-work
- •4.1. List of study practical tasks necessary to perform at the practical class.
- •Task 1. Coagulogram for dic-syndrome (disseminated intravascular coagulation) diagnostics
- •Task 2. To assess hematomic hemorrhagia type.
- •Task 3. To assess microcirculative (petekchio-spotted) haemorrhagia type
- •Task 4. To assess mixed (microcirculative-haematomic) bleeding type
- •Task 5. To get acquainted to doctor tactics at vasculite-purpure and microangiomatose bleedings types
- •5. Literature recommended:
- •6. Materials for self-control:
- •Lesson 38
- •Fibrinolysis and anticoagulants. Blood coagulation and fibrinolysis regulation
- •2. Study aims:
- •3.1.Basic knowledge, skills, experiences, necessary for study the topic:
- •3.2. Topic content
- •Table 5. Main primary physiological anticoagulants
- •Plasminogen
- •Hageman-dependent
- •Hageman-independent
- •Plasmin
- •Task 1. Blood fibrinolytic activity determining.
- •Task 2. Fibrinolytic bleeding laboratory diagnostics principles.
- •Task 3. Getting acquaintance with some tests characterizing hemostasis anticoagulant link
- •5. Literature recommended:
- •6. Materials for self-control:
- •Lesson 39
- •Total blood
- •2. Study aims:
- •3.1.Basic knowledge, skills, experiences, necessary for study the topic:
- •3.2. Topic content
- •Coagulogram changes in children
- •In mature new-borned
- •In immature new-borned:
- •Total blood
- •4. Literature recommended:
- •Lesson 40
- •Practical skills on blood system physiology
- •Glossary
- •Blood system physiology
- •Tests on blood physiology
6. Materials for self-control:
Control questions
Coagulational factors.
Coagulation mechanism.
Fibrin and fibrinogen degradation products and their role in hemostasis.
Oral cavity role in coagulational hemostasis support.
Positive paracoagulational probes at dental diseases.
Lesson 38
Fibrinolysis and anticoagulants. Blood coagulation and fibrinolysis regulation
1.The topic studied actuality. Anticoagulants and fibrinolysis represents powerful system in any organism that provides blood support in a liquid state. As it was mentioned above, oral cavity produces substances influencing on fibrinolysis. Maximal fibrinolytic activity has mixed saliva, less one – sublingual, minimal – parotid. There are plasminogen, its pro- and activators as well as inhibitors. There exists point of view that plasminogen activators role in saliva is in salivary ducts conductance preservation.
Any inflammation in its second phase is accompanied by fibrinolytic system activation.
2. Study aims:
To know: fibrinolysis process algorhythm and the process regulation, main primary and secondary anticoagulants; blood coagulation and fibrinolysis main regulative mechanisms.
To be able to: determine blood fibrinolytic activity.
3. Pre-auditory self-work materials.
3.1.Basic knowledge, skills, experiences, necessary for study the topic:
Subject |
To know |
To be able to |
Pathophysiology |
Main anticoagulants, their action mechanisms; fibrinolysis system work |
Explain main pathophysiological mechanisms of anticoagulative and fibrinolytic systems disturbances |
Pediatry with Neonatology |
Anticoagulative and fibrinolytic systems peculiarities in different-aged children; mentioned systems disturbances ethiology, pathogenesis, diagnostics, clinics, therapy and prophylaxy principles |
Treat and prevent anticoagulative and fibrinolytic systems disorders in different-aged children |
Internal Diseases |
Main anticoagulants, their action mechanisms; fibrinolysis system work; mentioned systems disturbances ethiology, pathogenesis, diagnostics, clinics, therapy and prophylaxy principles |
Treat and prevent anticoagulative and fibrinolytic systems disorders in internal diseases clinics |
Surgery |
Main anticoagulants, their action mechanisms; fibrinolysis system work; mentioned systems disturbances ethiology, pathogenesis, diagnostics, clinics, therapy and prophylaxy principles in surgery |
Treat and prevent anticoagulative and fibrinolytic systems disorders in the adult in surgical clinics |
Dentistry |
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