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In appearance. The skin is coarse and pitted, and has an oily appearance due to

the excessive secretion of the sebaceous material, and it is red or blue in

color due to vascular engorgement. Treatment consists in shaving off the excess

tissue to trim the nose to suitable size. Sufficient epithelial elements should

remain, so that skin grafting is not required.

Malignant tumours of the nose

Malignant tumours developing primarily in the sinuses usually originate in the

maxillary and ethmoidal sinuses, while primary nasal tumours arise more

frequently from the septum than from the lateral wall.

Pathology. The most common tumour is the squamous-cell carcinoma, which accounts

for 80% of the cases. Adenocarcinoma, adenoid cystic carcinoma and transitional

carcinoma, various types of sarcoma, fibrosarcoma, myxosarcoma, lymphosarcoma

and melanomas may also be found. The sarcomas tend to occur in younger people

and they act in a very malignant fashion.

Site of origin. Malignant tumours arise in the maxillary sinus, the ethmoidal

sinus, the frontal sinus and the sphenoidal sinus in that order of frequency,

the latter two being very rare. The site of origin within the sinus is often

difficult to determine as these tumours do not give rise to symptoms until they

have broken out of the bony sinus of origin. The majority arise at the junction

of the maxillary and ethmoidal sinuses. An exception to this is the

adenocarcinoma which is found in the ethmoidal cells of woodworkers in whom the

disease may be discovered early because, in certain areas, these workers are

screened at regular intervals for this tumour.

Symptoms. The presenting symptom depends upon the direction of spread of the

tumour. Inferior spread will give rise to symptoms in the palate-swelling or

erosion, loosening of teeth or, if the patient is edentulous, widening of the

alveolar ridge giving rise to ill-fitting dentures. Lateral spread will give

rise to swelling and redness of the cheek with obliteration of the buccal

sulcus. If the tumour spreads upwards and laterally it will give rise to eye

symptoms, epiphora from blockage of the nasolacrimal duct, diplopia due to

fixation of the inferior oblique or the inferior rectus muscle, and proptosis

with lateral displacement of the globe. Tumours spreading medially give rise to

nasal obstruction with an offensive purulent serosanguineous discharge from the

nose. Posterior spread towards the pterygoid plates causes spasm of the

masticatory muscles with trismus, and spread to the base of the skull causes

Intense headaches. In later disease pain is a prominent feature. Spread to lymph

nodes occurs late.

Clinical features. Anterior rhinoscopy shows invasion of the nasal cavity by a

friable granular tumour mass which bleeds readily.

Radiographic examination, including tomography, is important in assessing the

extent of the tumour before contemplating treatment. The most important areas to

assess are the superior spread to the anterior cranial fossa and the posterior

spread to the pterygoid plates which, if involved, means that curative surgical

removal is impossible.

Biopsy should be carried out under general or local anaesthetic.

Treatment. The best results are obtained from the combination of a full course

of external irradiation followed by radical surgery. The latter consists at the

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