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I.E. Cholesteatomatous erosion of the bony capsule of the labyrinth, usually the

horizontal semicircular canal but occasionally the promontory or other canals.

Diffuse labyrinthitis may be an extension of the circumscribed type but it more

frequently follows invasion through the oval or round windows, especially the

former. It involves the peri- and endolymphatic spaces. Diffuse labyrinthitis

may be serous or purulent. In serous labyrinthitis there is a general

non-purulent inflammation of the labyrinth with occasionally a fibrinous or

serous exudate. In purulent labyrinthitis there is infiltration of the spaces by

polymorphs, pus cells and destruction of the vestibular and cochlear structures.

Occasionally the bony capsule becomes involved.

Labyrinthitis may follow an acute otitis media, tuberculous otitis media or

chronic otitis media. Other causes of labyrinthitis include trauma, bloodborne

infection, bacterial or viral, and meningitis.

CLINICAL FEATURES Circumscribed labyrinthitis. There may be an initial bout of

vertigo and deafness in the formative stage of the fistula. Once the fistula is

established the main complaint may be of intermittent vertigo brought on by

sudden movements, cold water or air in the ear or, in more advanced cases, by

moving the auricle. There is usually evidence of chronic otitis media on

otoscopy and the diagnosis is confirmed by demonstrating a fistula sign, but a

negative fistula sign does not rule out a fistula. There may be a slight

sensorineural hearing loss in addition to the conductive hearing loss due to the

otitis media.

Serous labyrinthitis. This may follow circumscribed labyrinthitis or any of the

other causes mentioned. There is hearing loss, occasionally pain and tinnitus,

but the main feature is vertigo, associated with nausea and vomiting. There may

be a sensation of objects moving from the diseased to the healthy side, i.e.

nystagmus, towards the diseased side. The patient invariably is bed-ridden, at

least initially, and lies on the unaffected ear and looks towards the diseased

side because this reduces the vertigo. As a rule there is no pyrexia. Caloric

reactions, if tested after the acute phase, are diminished on the affected side.

Purulent labyrinthitis. The symptoms are similar to those of serous

labyrinthitis but the vertigo and vomiting may be more frequent and severe.

Nystagmus, although initially directed towards the diseased ear, soon changes

direction towards the good ear. Total deafness develops. Caloric testing should

not be done during the acute phase because it can exacerbate roe vertigo, but if

done later a canal paresis is commonly found on the affected side. There is no

pyrexia unless there is an intracranial complication.

TREATMENT Circumscribed labyrinthitis. Suspicion of labyrinthine erosion by

cholesteatoma or granulations is an indication for surgery. Tomography may show

labyrinthine erosion. The mastoid is cleared of disease by a modified radical

mastoidectomy. The fistula may be exteriorized if caused by cholesteatoma. In

some cases the cholesteatoma can be removed and the fistula is covered by

temporalis fascia.

Serous labyrinthitis and purulent labyrinthitis. Bed-rest is essential in the

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