
- •Список сокращений
- •Введение
- •Литературный обзор Факторы роста Общие сведения
- •Классификация факторов роста
- •Колониестимулирующий фактор гранулоцитов (g-csf)
- •Васкулярно-эндотелиальный фактор роста vegf. Общие сведения
- •Классификация и разновидности vegf
- •Васкулярно-эндотелиальный фактор роста (vegf 165)
- •Васкулярно-эндотелиальный фактор роста (b) vegf 165b
- •Участие vegf в ангиогенезе.
- •Vegf рецепторы
- •Материалы
- •Результаты и обсуждение
- •Список литературы.
Список литературы.
Los M, Roodhart JM, Voest EE (April 2007). "Target practice: lessons from phase III trials with bevacizumab and vatalanib in the treatment of advanced colorectal cancer". The Oncologist 12 (4): 443–50. doi: 10.1634/theoncologist. 12-4-443. PMID 17470687.
Growth factor at Dorland's Medical Dictionary.
Goustin A.S. Leof E.B. Shipley G.D., Moses H.L. Growth factors and cancer. Cancer Res. 1986 Mar;46(3):1015-29.
Марри Р. и др. Биохимия человека. М., 1993.
Stoker M, Gherardi E. Regulation of cell movement: the motogenic cytokines. Biochim. Biophys. Acta 1072 ( 1991 ), 81
Deuel T.F. Polypeptide growth factors: roles in normal and abnormal cell growth. Annu Rev Cell Biol. 1987;3:443-92.
Datto, M.B., Hu, P.P., Kowalik, T.F., Yingling, J., and Wang, X.F. (1997) Mol. Cell. Biol., 17, 2030-2037.
Cross M, Dexter T.M. Growth factors in development, transformation, and tumorigenesis. Cell. 1991 Jan 25;64(2):271-80.
Коган А. Х. Патофизиология опухолей М., 1991
Reddi AH, Reddi A (2009). "Bone morphogenetic proteins (BMPs): from morphogens to metabologens". Cytokine & growth factor reviews 20 (5-6): 341–2. doi:10.1016/j. cytogfr.2009.10.015. PMID 19900831
Carpenter G, Cohen S (May 1990). "Epidermal growth factor". The Journal of Biological Chemistry 265 (14): 7709–12. PMID 2186024.
Siren AL et al. (2001). "Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress". Proc Natl Acad Sci USA 98 (7): 4044–4049. doi:10.1073/pnas. 051606598. PMC 31176. PMID 11259643.
Finklestein S.P., Plomaritoglou A. (2001). "Growth factors". In Miller L.P., Hayes R.L., eds. Co-edited by Newcomb J.K.. Head Trauma: Basic, Preclinical, and Clinical Directions. New York: Wiley. pp. 165–187. ISBN 0471360155.
Sallerfors B, Olofsson T (1993). "Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) secretion by adherent monocytes measured by quantitative immunoassays". Eur. J. Haematol. 49 (4): 199–207.
Nakamura T (1992). "Structure and function of hepatocyte growth factor.".Prog. Growth Factor Res. 3 (1): 67–85.doi:10.1016/0955-2235(91)90014-U.PMID 1838014.
Cohen P, Peehl DM, Lamson G, Rosenfeld RG (1991). "Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells". Journal of Clinical Endocrinology and Metabolism 73 (2): 401–7. doi:10.1210/jcem-73-2-401. PMID 1713219.
Hannink M, Donoghue DJ (1989). "Structure and function of platelet-derived growth factor (PDGF) and related proteins".Biochim. Biophys. Acta 989 (1): 1–10. PMID 2546599.
Luetteke NC, Lee DC (1991). "Transforming growth factor alpha: expression, regulation and biological action of its integral membrane precursor". Semin. Cancer Biol. 1 (4): 265–75. PMID 2103501.
Khalil N (1999). "TGF-beta: from latent to active". Microbes Infect1 (15): 1255–63. doi:10.1016/S1286-4579(99)00259-2.PMID 10611753.
Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, Lanctôt KL (2010). "A meta-analysis of cytokines in major depression". Biol Psychiatry 67 (5): 446–457.
Ferrara N, Davis-Smyth T. The biology of vascular endothelial growth factor. Endocr Rev. 1997 Feb;18(1):4-25. PMID:9034784
Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev. 2004 Aug;25(4):581-611. PMID:15294883 doi:10.1210/er. 2003-0027.
Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci. 2001 Mar;114(Pt 5):853-65. PMID:11181169.
Muller YA, Christinger HW, Keyt BA, de Vos AM. The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding. Structure. 1997 Oct 15;5(10):1325-38
Muller YA, Li B, Christinger HW, Wells JA, Cunningham BC, de Vos AM. Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7192-7. PMID:9207067.
Bates DO, Cui TG, Doughty JM, Winkler M, Sugiono M, Shields JD, Peat D, Gillatt D, Harper SJ. VEGF165b, an inhibitory splice variant of vascular endothelial growth factor, is down-regulated in renal cell carcinoma. Cancer Res. 2002 Jul 15;62(14):4123-31.
B. A. Keyt, L. T. Berleau, H. V. Nguyen, H. Chen, H. Heinsohn, R. Vandlen, N. Ferrara. The Carboxy-terminal Domain (111-165) of Vascular Endothelial Growth Factor is Critical for its Mitogenic Potency. J. Biol. Chem., 1996, 271, 7788-7795.
John S. Penn (11 March 2008). Retinal and Choroidal Angiogenesis. Springer. pp. 119–. ISBN 9781402067792. Retrieved 26 June 2010.
http://www.ncbi.nlm.nih.gov/books/NBK10107/
Burri, PH; Hlushchuk, R; Djonov, V (2004). "Intussusceptive angiogenesis: its emergence, its characteristics, and its significance". Dev Dyn. 231 (3): 474–88. doi:10.1002/dvdy.20184. PMID 15376313.
Keyt BA, Nguyen HV, Berleau LT, Duarte CM, Park J, Chen H, Ferrara N. Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis. J Biol Chem. 1996 Mar 8;271(10):5638-46. PMID:8621427.
Pieren M, Prota AE, Ruch C, Kostrewa D, Wagner A, Biedermann K, Winkler FK, Ballmer-Hofer K. Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity. J Biol Chem. 2006 Jul 14;281(28):19578-87. Epub 2006 May 3. PMID:16672228 doi:10.1074/jbc.M601842200
W. J.Fairbrother, M. A. Champe, H. W. Christinger, B.A. Keyt, M. A Starovasnik, Solution structure of the heparin-binding domain of vascular endothelial growth factor. Structure 1998, 15; 6(5), 637-48.
Reviews: VEGF receptor signalling - in control of vascular function (Anna-Karin Olsson, Anna Dimberg, Johan Kreuger and Lena Claesson-Welsh).
Koch A.E., Harlow L.A., Haines G.K., Amento E.P., Unemori E.N., Wong W.L., Pope R.M. and Ferrara N. Vascular endothelial growth factor. A cytokine, modulating angiogenesis in rheumatoid arthritis. J. Immunol. 1994. 152, 4149-4156.
Folkman J. and Klagsbrun M. Angiogenic factors (review). Science. 1987. 235, 442-447.
Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med. 2003 Jun;9(6):669-76.