Подготовка у универсиаде 2012 / hcv_genome_and_protein_processing
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Hepatitis C Virus
and Nonstructural Proteins
Hepatitis C Proteins
Structural Proteins |
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Nonstructural (NS) Proteins |
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C |
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E1 |
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E2 |
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p7 |
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NS2 |
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NS3 |
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NS4A |
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NS4B |
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NS5A |
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NS5B |
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Envelope |
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Cysteine |
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Serine Protease |
RNA binding and assembly |
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Glycoprotein |
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Protease |
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Cofactors |
recognition complex |
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Envelope |
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Vioporin |
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Serine |
RNA |
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Membranous |
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RNA- |
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Glycoprotein |
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Protease |
Helicase |
Web Induction |
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RNA |
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web
Hepatitis C Virus
Translation
Enzymes Involved in Protein Processing
Polyprotein Precursor
Signal Peptidase NS3/4A Serine Protease
C |
E1 |
E2 |
p7 |
NS2 |
NS3 |
A NS4 B |
A |
NS5 |
B |
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Hepatitis
web study
Hepatitis C Genome
Translation
Protein Processing
Role of NS3/4A Serine Protease
Polyprotein Precursor
Signal Peptidase NS3/4A Serine Protease
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C |
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E1 |
E2 |
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p7 |
NS2 |
NS3 |
A NS4 B |
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A |
NS5 |
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B |
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Protein Processing |
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Proteins |
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C |
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E1 |
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E2 |
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p7 |
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NS2 |
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NS3 |
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NS4A |
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NS4B |
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NS5A |
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NS5B |
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Hepatitis
web study
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Hepatitis C Virus |
NS3/4A |
Protease Inhibitors |
NS3/4A Serine Protease Inhibitors
Polyprotein Precursor
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Signal Peptidase |
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NS3/4A Serine Protease |
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C |
E1 |
E2 |
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p7 |
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NS2 |
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NS3 |
A NS4 B |
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A |
NS5 |
B |
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Proteins |
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C |
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E1 |
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E2 |
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p7 |
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NS2 |
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NS3 |
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A NS4 B |
A |
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NS5 |
B |
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Hepatitis
web study
Hepatitis C NS3/4a Serine Protease
Hepatitis C Virus
NS3 Protein
NS3
Nonstructural (NS) protein
Size = 632 amino acids
Hepatitis
web study
Hepatitis C Virus
NS3 Protein
Helicase
Serine
Protease
Nonstructural (NS) protein Size = 632 amino acids
Components: Helicase (C-terminal) & Serine Protease (N-terminal)
Hepatitis
web study
Hepatitis C Virus
NS3 Protein
3 1
Helicase 2
Serine Protease
N-Terminal Region |
Serine |
Helicase |
Helicase |
Helicase |
C-Terminal Region |
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Protease |
Domain 1 |
Domain 2 |
Domain 3 |
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Amino Acid |
1-187 |
188-326 |
327-480 |
481-632 |
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Hepatitis
web study
Hepatitis C Virus
NS3/4A Protein Complex
NS3
NS4A
NS3 Complexed with NS4A
Hepatitis
web study
Hepatitis C Virus
NS3/4A Serine Protease Active Site
Helicase
NS3
Protease Active Site
Protease
NS4A
Hepatitis
web study