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420 The ASCRS Manual of Colon and Rectal Surgery
Clinical Presentation
• As previously described, the patient is typically a male nurs­ing home resident, on psychotropic medications, with a history of chronic constipation. These patients may not complain of pain, but rather a caregiver notices an extremely long interval between bowel movements, associated with signifi cant abdom­inal distension.
• It has been reported that 40–60% of patients will give a history of having had similar episodes.
• On presentation, the distension is often dramatic. Unlike the patient with fecal impaction, the rectal ampulla is empty.
• Plain abdominal fi lms typically show massive colonic disten­sion, with or without small bowel dilatation (depending on the competence of the ileocecal valve). The very large sigmoid loop will be orientated toward the right upper quadrant. The adjacent walls of the sigmoid will appear to be thickened, aris­ing out of the left lower quadrant, giving the classical “bent inner tube” sign (Fig. 19.6A ).
• Plain abdominal X-rays alone are diagnostic in 60–75% of cases. However, the massive distension may, occasionally, make the diagnosis diffi cult to establish with certainty. In those cases, a contrast enema should be obtained. This study will show the obstruction at the rectosigmoid junction, with the classical bird’s beak confi guration (Fig. 19.6B ).
• The addition of barium enema to the plain abdominal X-rays may increase the diagnostic yield to near 100%.
• The major diagnosis from which sigmoid volvulus must be dis­tinguished is colonic obstruction caused by neoplasm. – Usually the abdominal X-rays can distinguish one from
the other; however, in the presence of truly massive dis­tension, differentiation may be diffi cult.
– At the time of attempted sigmoidoscopic detorsion, the
obstructing neoplasm will hopefully be visualized and the true diagnosis will be apparent.
• The other condition that may cause clinical confusion is colonic megacolon associated with abnormal colonic motility. This condition also presents in elderly, constipated nursing home patients. The X-rays can look remarkably similar. Because rectal tube decompression will generally rapidly and success­fully relieve the distension associated with this form of mega­colon, distinction from volvulus can be diffi cult.
19. Colonic Volvulus 421
ba
Fig. 19.6. ( a ) Plain abdominal X-ray of a sigmoid volvulus indicating the “bent inner tube” sign. ( b ) Barium enema study of a sigmoid volvulus indicating the bird’s beak deformity and complete obstruction to retrograde fl ow of contrast.
Treatment/Outcome
• The patient with sigmoid colon volvulus should be hydrated and resuscitated.
• The mainstay of emergency therapy has generally been detor­sion and decompression.
• Detorsion of sigmoid volvulus has been described using several techniques, including rigid proctoscopy, fl exible sig­moidoscopy or colonoscopy, blind passage of a rectal tube, and use of a column of barium during barium enema examination. Successful decompression using one of these techniques is generally reported in the range of 70–80%.
• A signifi cant concern is that the sigmoid may already be gangrenous.
• If ischemic mucosa is visualized, attempts at detorsion should be immediately abandoned and operative intervention should be undertaken emergently.
• For this reason, the authors strongly recommend using only those detorsion techniques that visualize the mucosa before
422 The ASCRS Manual of Colon and Rectal Surgery
detorsion. Attempts at detorsion via blind passage of a rectal tube should be avoided.
• The major complication associated with attempted detorsion is inadvertent perforation. This is more likely in the presence of gangrene, but can occur with viable bowel as well.
• Once decompression has been accomplished, there is usually forceful evacuation of fl atus and stool (frequently all over the clothes and shoes of an unsuspecting novice) and visible defl a­tion of the patient’s abdominal distension.
• A rectal tube should then be gently inserted into the colon to a point proximal to the site of the twist (which is usually within 20 cm of the anus). The tube should then be fi xed in place, to allow continued decompression and prevention of recurrence.
• A plain abdominal fi lm should be obtained to document decompression and the patient should be admitted to the hos­pital.
• Successful detorsion provides the advantage of converting a surgical emergency to an elective situation.
• Over the next several days, bowel function is likely to return to normal. Medical conditions (cardiac, pulmonary, renal, etc.) should be addressed, electrolyte abnormalities should be cor­rected, and the patient’s condition optimized.
• Colonoscopy, to rule out a proximal lesion, should be per­formed, and then a decision must be made. The rectal tube can be safely removed and the patient could be discharged from the hospital; however, it is well established that the rate of recurrent sigmoid volvulus is in excess of 25%. In fact, most authors document a recurrence rate of greater than 50%, and some report recurrences as high as 80–90%.
• The standard elective surgical procedure is sigmoid resec­tion with primary anastomosis; however, a number of nonresective techniques have been described, including nonsurgical endoscopic sigmoidopexy with or without tube fi xation, extraperitoneal sigmoidopexy, sigmoidopexy to the transverse colon and/or the parieties, mesosigmoplasty, col­opexy with banding, mesenteric fi xation, and laparoscopic fi xation.
• Although several authors have reported excellent results using pexy without resection, others have reported recurrence rates in excess of 25%.
19. Colonic Volvulus 423
• The technique of mesosigmoidoplasty deserves discussion. This procedure is performed by incising the elongated sigmoid mesentery vertically along its axis. Peritoneal fl aps are then
created which are then approximated transversely (Fig. 19.7 ). – This procedure thereby creates a shortened, broad mesen-
tery precluding future bowel rotation.
– Although one author has reported a recurrence of 28%,
most report recurrences of less than 2%. Mortality ranges from 0 to 7%.
• Resection with anastomosis, therefore, should currently be considered the standard of care for elective cases. However, in circumstances in which continence is an issue, an end stoma may be a better alternative.
• Laparoscopic techniques have also been applied, but in general, because the redundant distended colon obscures the working space and the incision required to deliver the specimen is also large enough to exteriorize the redundant sigmoid colon and
Fig. 19.7. Mesosigmoidoplasty. ( a ) A longitudinal peritoneal incision is made in the elongated, narrow mesentery. ( b ) The incision is then closed transversely, broadening the mesenteric base and shortening the height of the sigmoid loop.
424 The ASCRS Manual of Colon and Rectal Surgery
perform an adequate resection and anastomosis, there is little to be gained by the use of laparoscopy.
• If decompression is not possible, if the patient has signs and symptoms of peritonitis or colonic ischemia, or if gangrenous mucosa is visualized during attempted decompression, the sit­uation becomes a surgical emergency.
• The volvulus should be manually reduced if the bowel is viable, and the redundant, twisted sigmoid should be resected. How­ever, when gangrenous bowel is encountered during laparotomy, detorsion should not be performed. Accumulated toxins and bacteria may be released into the circulation, resulting in sepsis and cardiovascular collapse.
• Generally, an anastomosis should be avoided if the proximal colon is massively dilated and loaded with feces.
• A single prospective, randomized trial comparing primary anastomosis to the Hartmann’s procedure in 14 patients with gangrenous bowel, revealed a 50% anastomotic leak rate. In addition, mortality was more than double in those patients in whom an anastomosis was performed (33 vs. 13%).
• Overall mortality rates for the treatment of sigmoid volvulus range from 14 to 45%.
• Elective surgery, after detorsion, is currently associated with mortality rates below 10%, despite the fact that these are gen­erally patients with multiple comorbidities.
• Finally, operative detorsion with or without pexy carries a sim­ilar mortality to elective resection and anastomosis (8–14%). Therefore, one must consider the overall risk of recurrence as well as the risk of mortality.
• As expected, any nonresectional procedure carries a substan­tial risk of recurrence. For decompression alone it ranges from 25 to 70%, whereas detorsion, with or without pexy, has been associated with recurrence rates of 23–40%.
• Most authors indicate that the risk of recurrence after resection approaches zero.
• The only prospective randomized trial comparing elective resection and primary anastomosis with mesosigmoidoplasty confi rms these fi ndings. None of the resected patients and 29% of the plastied patients experienced recurrence. However, there was no mortality in the plasty group as compared with 10% in the resection group.
19. Colonic Volvulus 425
F. Ileosigmoid Knotting
Incidence and Epidemiology
• Ileosigmoid knotting, also called compound volvulus, is a rare form of volvulus in the West. It is, however, comparatively more common in certain areas of Africa, Asia, and the Middle East. In particular, large series are reported from Turkey, Rus­sia, Scandinavia, Uganda, and India.
• The geographic distribution corresponds with regions of the world where diets high in bulk and carbohydrates are con­sumed with large volumes of liquid. The incidence is high­est in groups in which one single large meal is consumed daily.
Pathogenesis/Etiology
• Theories of the pathogenesis of ileosigmoid knotting focus on a large volume diet high in bulk and carbohydrates, associated with large volumes of concomitant liquid ingestion. This may lead to an elongated abnormally mobile small intestinal mesen­tery, in addition to a long narrow pedicled sigmoid mesentery (Fig. 19.8 ).
Clinical Presentation
• The presentation of ileosigmoid knotting is one of acute onset, often with a fulminant course.
• At surgery, gangrenous intestine is found in 70–100% of cases.
• Clinically, the patient’s condition presents as a small bowel obstruction, but radiographic evaluation is more consistent with a large intestinal obstruction.
Treatment/Outcome
• Because of the high incidence of ischemia and gangrene at the time of presentation, after an initial period of rapid resuscita­tion and antibiotic administration, patients should be taken for emergent abdominal exploration.
426 The ASCRS Manual of Colon and Rectal Surgery
Fig. 19.8 Ileosigmoid knotting: these schematic illustrations indicate the four forms of knotting. The active ileum may rotate around the sigmoid colon in either a clockwise ( a ) or counterclockwise ( b ) direction. Much more infrequently, the sigmoid colon may act as the active loop and rotate in either a clockwise ( c ) or counterclockwise ( d ) direction around the ileum.
• Because of the high likelihood of gangrenous bowel, most authors advocate en bloc resection of both segments of intes­tine without attempts to untwist the bowel.
• Although most perform a primary ileoileal or ileocolic anasto­mosis in patients with gangrenous small bowel, a Hartmann’s procedure is usually performed when the sigmoid is found to be nonviable.
• Overall surgical mortality generally ranges from 30 to 50%.
20. Lower Gastrointestinal Hemorrhage
A. Introduction
• Lower gastrointestinal hemorrhage refers to a spectrum of intestinal bleeding that arises distal to the ligament of Treitz. It may range from occult bleeding or occasional spotting of blood to massive lower intestinal hemorrhage.
• True massive intestinal hemorrhage typically involves hemo­dynamic compromise or acute symptomatic anemia.
• Multiple sources defi ne massive bleeding to include patients with an acute drop in their hematocrit to less than 30%, patients with transfusion requirements (up to 3–5 units of blood/blood products), or orthostasis requiring resuscitation.
• Melena typically suggests bleeding from a more proximal source in the colon or small intestine.
• Hematochezia suggests left colonic, rectal, or anal sources.
• Overall, it is believed that upper sources may present with lower gastrointestinal bleeding symptoms in 10–15% of cases.
• Most often the intestinal bleeding resolves spontaneously often while undergoing supportive hospital care.
• In clinical scenarios in which the bleeding resolved sponta­neously, the diagnostic evaluation may only unmask potential sources. Without associated attached clot or active bleeding, the true site of hemorrhage may never be elucidated.
• Current treatment regimens incorporate remediating the impact of long-term anticoagulants and antiplatelet agents for under­lying cardiovascular conditions. Hemorrhage in these patients proves more life-threatening.
D.E. Beck et al. (eds.), The ASCRS Manual of Colon and Rectal Surgery, 427 DOI: 10.1007/978-0-387-73440-8_20, © Springer Science + Business Media, LLC 2009
428 The ASCRS Manual of Colon and Rectal Surgery
B. Etiologies
• Common causes for lower gastrointestinal hemorrhage include colonic diverticula, angiodysplasia, ischemic colitis, and infl ammatory bowel disease. Hemorrhage may also stem from intestinal tumors or malignancies.
• Unusual causes include nonsteroidal antiinfl ammatory drug (NSAID)-related nonspecifi c colitis, Meckel’s diverticulum, and anorectal diseases.
Diverticular Disease
• The precise mechanism of diverticular hemorrhage is unknown.
• It is generally accepted that thinning of the media in the vasa recta predisposes to intraluminal rupture: focal injury may occur from trauma related to a fecalith.
• It is unclear how frequently diverticula are the true cause of hemorrhage.
• Diagnostic evaluations, such as colonoscopy, often do not identify a precise source for the hemorrhage without the pres­ence of witnessed bleeding or an adherent clot.
• Despite being considered a major source for colonic hemor­rhage, bleeding from diverticula is a relatively rare event affecting only 4–17% of patients with diverticulosis.
• In most cases, bleeding ceases spontaneously, but in 10–20% of cases, the bleeding continues unabated in the absence of intervention.
• The risk of rebleeding after an episode of bleeding is approxi­mately 25% but increases to 50% among patients who have had two or more prior episodes of diverticular bleeding.
• Right sided colonic diverticula occur less frequently than left sided or sigmoid diverticula but are thought to be responsible for a disproportionate incidence of diverticular bleeding. This fi nding is not well established, however, and there is often diffi culty distinguishing between bleeding from an arterio­venous malformation or angiodysplasias and bleeding from diverticulosis.
• Operative management of diverticular bleeding is indicated when bleeding continues unabated and is not amenable to ang­iographic or endoscopic therapy.
20. Lower Gastrointestinal Hemorrhage 429
– It also should be considered in patients with recurrent
bleeding localized to the same colonic segment.
– In a stable healthy patient, the operation consists of a
segmental bowel resection (usually a right colectomy or sigmoid colectomy) followed by a primary anastomosis.
Angiodysplasia
• Angiodysplasias are thin-walled arteriovenous communications located within the submucosa and mucosa of the intestine.
• Angiodysplasias may be congenital or, more typically, acquired.
• In the acquired form, distortions of the postcapillary venules may arise as a degenerative lesion associated with increases in intraluminal pressure. The intraluminal pressure occurs from loss of the precapillary sphincter and a resultant increased pressure transmitted through the capillary bed into the venules. As these vessels respond to the arterial fl ow, it results in thickening and ectasia. The vessels eventually entangle as tufts within the submucosa and erode into the mucosa proper.
• No one is quite certain precisely why angiodysplasias occur. Current hypotheses suggest a loss of vascular integrity related to loss of transforming growth factor (TGF) b signaling cascade or from a defi ciency in mucosal type IV collagen.
• Angiodysplasias are uncommon before age 60, increase with age, and are associated with aortic stenosis (Heyde’s syndrome), chronic renal failure, and von Willebrand’s disease.
• Osler-Weber-Rendu (hereditary hemorrhagic telangiectasias) is a hereditary condition with telangiectasias of the lung, nervous system, skin, and intestine.
• When angiodysplasias are noted during angiography or colon­oscopy, unless a hemorrhagic blush is seen during the angiogram or colonoscopy, it is diffi cult to accurately accuse this malady as the source of hemorrhage.
• Angiography remains the gold standard for the diagnosis of angiodysplasia.
• In the arterial phase, the radiographic fi ndings of angiodysplasia demonstrate early venous fi lling which normally occurs in later phases.
• When angiography identifi es a bleeding angiodysplasia, treatment with embolization therapy or directed infusion of vasopressin will decrease or stop the bleeding.