has been designed very specifically to sup port an inte­grated approach to learning medicine. Our carefully selected panel of authors drawn from across the English­speaking world have combined basic sci ence with clinical application. Links to clinical skills, clinical inves­tigation and therapeutics are made clear throughout.

Whatever curriculum you follow, wherever you are in the world, and whichever stage you are at, we know that the Systems of the Body volumes will serve as great places to start when learning something new and enable you to effectively piece together the essential compo­nents of each major body system, in a modern clinical context.

Chelmsford, UK

teaching both preclinical and biomedical scientists on the subject has highlighted a continued disconnect between the descriptive physiology of the gastrointestinal tract and clinical manifestations. Thus, in this edition, there is increased integration between the basic science and clini­cal cases of common diseases presenting in healthcare settings, enabling the reader to easily grasp the under­pinning physiological changes associated with disease. Furthermore, gastrointestinal pathologies and treatment pathways are now described within their respective chapters to better compartmentalise information. Finally, this edition now includes a chapter on the intestinal microbiome, a subject which has come to the fore in the last decade, becoming incredibly important to gastroin­testinal biology and is now implicated in many intestinal and extra- intestinal diseases and processes.