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Berdimurodov Elyor Tukhliyivich and Dakeshwar Kumar Verma (Eds.)
Carbon Dots in Biology

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Carbon Dots
in Biology
Synthesis, Properties, Biological
and Pharmaceutical Applications
Edited by
Berdimurodov Elyor Tukhliyivich
and Dakeshwar Kumar Verma

Editors
https://t.me/medicina_free
Berdimurodov Elyor Tukhliyivich
Faculty of Chemistry
National University of Uzbekistan
Tashkent 100034
Usbekistan
elyor170690@gmail.com
Dr. Dakeshwar Kumar Verma
Govt. Digvijay Autonomous
Postgraduate College
Chhattisgarh
Rajnandgaon 491441
India
dakeshwarverma@gmail.com
ISBN 978-3-11-079992-7
e-ISBN (PDF) 978-3-11-079995-8
e-ISBN (EPUB) 978-3-11-086033-7
Library of Congress Control Number: 2022951129
Bibliographic information published by the Deutsche Nationalbibliothek
The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie;
detailed bibliographic data are available on the internet at http://dnb.dnb.de.
© 2023 Walter de Gruyter GmbH, Berlin/Boston
Cover image: RED_SPY/iStock/Getty Images Plus
Typesetting: Integra Software Services Pvt. Ltd.
Printing and binding: CPI books GmbH, Leck
www.degruyter.com

Contents
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About the editors VII
List of contributors IX
Elyor Berdimurodov, Khasan Berdimuradov, Kholmurodov Bahodir, Abduvali Kholikov,
Khamdam Akbarov, Omar Dagdag, Mohamed Rbaa, Brahim El Ibrahimi,
Dakeshwar Kumar Verma, Rajesh Haldhar and Pramod Kumar Mahish
Chapter 1
Recent trends and developments in carbon dots 1
Omar Dagdag, Rajesh Haldhar, Seong-Cheol Kim, Elyor Berdimurodov,
Ekemini D. Akpan and Eno E. Ebenso
Chapter 2
Main properties and characteristics of carbon dots 15
Vinayak Sahu
Chapter 3
Synthetic strategies of carbon dots 23
Abhinay Thakur, Ashish Kumar
Chapter 4
Carbon dots in biosensing 43
Palesa Seele
Chapter 5
Carbon dots in detection of biological molecules and metal ions 77
Manoj Kumar Banjare, Kamalakanta Behera, Ramesh Kumar Banjare
and Siddharth Pandey
Chapter 6
Carbon dots in nanozymes 109
Muhammad Alamgeer
Chapter 7
Carbon dots in food safety detection 139

VI Contents
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Sonali Loya and Swati Chandravanshi
Chapter 8
Carbon dots in anticancer detection and therapy 157
Mahdie Matin, Mahtab Mirhoseinian, Alireza Alikhanian, Golnar Bayatani,
Mohammad Nazari Montazer, Mohammad Mahdavi, Burak Tüzün
and Parham Taslimi
Chapter 9
Carbon dots in photodynamic therapy 189
Saima Ashraf, Fahmida Jabeen, Sabeen Iqbal, Muhammad Salman Sajid,
Muhammad Naeem Ashiq and Muhammad Najam-ul-Haq
Chapter 10
Carbon dots in photothermal therapy 219
Shokoh Parham, Seyedeh-Shirin Parham and Hadi Nur
Chapter 11
Carbon dots in antibacterial, antiviral, antifungal,
and antiparasitic agents 241
Golnar Bayatani, Mahdie Matin, Alireza Alikhanian, Mahtab Mirhoseinian,
Mohammad Nazari Montazer, Burak Tuzun, Mohammad Mahdavi, Parham Taslimi
Chapter 12
Carbon dots in antibiosis: disinfection and sterilization 259
Nicole Remaliah Samantha Sibuyi, Anelisiwe Mbengashe, Zimkhitha Bianca
Nqakala, Antoinette Alliya Ajmal, Tswellang Mgijima, Cate Malope Mashilo,
Aluwani Matshaya, Samantha Meyer, Mervin Meyer, Martin Opiyo Onani,
Abram Madimabe Madiehe and Adewale Oluwaseun Fadaka
Chapter 13
Carbon dots in drug delivery 283
N.B. Iroha, C.O. Ezenwaka, C.N. Opara and F.E. Abeng
Chapter 14
Carbon dots in protein and nucleic acid delivery 313
Index 325

About the editors
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Berdimurodov Elyor is an associate professor at the National
University of Uzbekistan. He has studied in the PhD programme at Tianjin
University and the National University of Uzbekistan. He was a researcher
at Tianjin University, Karshi State University, and Changchun Applied
Chemistry Institute (Chinese Academy of Science). He was a participant in
several international and domestic study and research programmes
(Chinese Government Scholarships, Chinese great belt programme,
National Fundamental, and practical grants). He has published around 22
articles in Scopus and Web of Science journals. H-index is 7 in Scopus, 7 in
Web of Science, and 11 (i-10 index of 11) in Google Scholar. He has
contributed over 12 book chapters to edited books. He was also a
participant in over 15 international conferences from China, Russian, India, and other developed
countries. His research areas are corrosion science, electrochemistry, quantum chemistry, material
science, green chemistry, biology, medicine, pharmacy, and nanochemistry.
Berdimurodov Elyor Tukhliyivich Faculty of Chemistry, National University of Uzbekistan, Tashkent
100034, Uzbekistan, elyor170690@gmail.com
Dakeshwar Kumar Verma’s research is mainly focused on the
preparation and designing of organic and inorganic materials,
nanomaterials that are useful for several industrial applications and
material science. Dr Verma is the author of more than 60 research papers,
review articles, and book chapters in peer-reviewed international journals
published by ACS, RSC, Wiley, Elsevier, Springer, Taylor & Francis, etc.
Additionally, he has published 8 edited/authored books with Elsevier,
Wiley, and De Gruyter. He is also serving as an editor/author for various
books that will be published by Elsevier, Wiley, Taylor & Francis, and De Gruyter. He has more than 850
citations with an H-index of 17 and an i-10 index of 24. Recently, two full-time PhD research scholars are
working under his guidance. Dr Verma received the Council of Scientific and Industrial Research Junior
Research Fellowship award in 2013. He also availed MHRD national fellowship during his PhD in 2013.
Dakeshwar Kumar Verma, PhD Assistant Professor, Department of Chemistry, Govt. Digvijay
Autonomous Postgraduate College, Rajnandgaon, Chhattisgarh 491441, INDIA, dakeshwarverma@gmail.com
https://doi.org/10.1515/9783110799958-203

List of contributors
https://t.me/medicina_free
Elyor Berdimurodov
Faculty of Chemistry
National University of Uzbekistan
Tashkent, 100034
Uzbekistan
Khasan Berdimuradov
Faculty of Industrial Viticulture and Food
Production Technology
Shahrisabz branch of Tashkent Institute of
Chemical Technology
Shahrisabz, 181306
Uzbekistan
Kholmurodov Bahodir
Faculty of Industrial Viticulture and Food
Production Technology
Shahrisabz branch of Tashkent Institute of
Chemical Technology
Shahrisabz, 181306
Uzbekistan
Abduvali Kholikov
Faculty of Chemistry
National University of Uzbekistan
Tashkent, 100034
Uzbekistan
Mohamed Rbaa
Laboratory of Organic Chemistry
Catalysis and Environment, Faculty of Sciences
Ibn Tofail University
PO Box 133
14000, Kenitra
Morocco
Brahim El Ibrahimi
Department of Applied Chemistry
Faculty of Applied Sciences
Ibn Zohr University
Morocco
Dakeshwar Kumar Verma
Department of Chemistry
Government Digvijay Autonomous Postgraduate
College
Rajnandgaon
Chhattisgarh 491441
India
Rajesh Haldhar
School of Chemical Engineering
Yeungnam University
Gyeongsan, 712749
South Korea
Khamdam Akbarov
Faculty of Chemistry
National University of Uzbekistan
Tashkent, 100034
Uzbekistan
Omar Dagdag
Centre for Materials Science
College of Science
Engineering and Technology
University of South Africa
Johannesburg 1710
https://doi.org/10.1515/9783110799958-204
Pramod Kumar Mahish
Department of Biotechnology
Government Digvijay Autonomous Postgraduate
College
Rajnandgaon
Chhattisgarh 491441
India
Seong-Cheol Kim
School of Chemical Engineering
Yeungnam University
Gyeongsan 38541
Republic of Korea

X List of contributors
https://t.me/medicina_free
Ekemini D. Akpan
Institute for Nanotechnology and Water
Sustainability
College of Science
Engineering and Technology
University of South Africa
Johannesburg 1710
South Africa
Eno E. Ebenso
Institute for Nanotechnology and Water
Sustainability
College of Science
Engineering and Technology
University of South Africa
Johannesburg 1710
South Africa
Vinayak Sahu
National Institute of Technology Raipur;
And
Governmental Model College Raipur
Chhattisgarh
India
Email: vinayaksahu2208@gmail.com
Abhinay Thakur
Department of Chemistry
School of Chemical Engineering and Physical
Sciences
Lovely Professional University
Phagwara, Punjab
India
Ashish Kumar
NCE, Department of Science and Technology
Government of Bihar
India
Email: drashishchemlpu@gmail.com
Palesa Seele
MINTEK
South Africa
Manoj Kumar Banjare
MATS School of Sciences
MATS University
Pagaria Complex
Pandri, Raipur (C.G.), 492004
India
Kamalakanta Behera
Department of Chemistry
University of Allahabad
Prayagraj
Uttar Pradesh 211002
India
Ramesh Kumar Banjare
MATS College
MATS University
Aarang (C.G.), 492004
India
Siddharth Pandey
Department of Chemistry
Indian Institute of Technology Delhi
Hauz Khas
New Delhi, 110016
India
MUHAMMAD ALAMGEER
Khwaja Fareed University of Engineering and
Information Technology
Rahim Yar Khan
Pakistan
Sonali Loya
Govt. Nehru P.G. college
Dongargarh
Chhattisgarh
INDIA
Swati Chandravanshi
Govt. Nehru P.G. college
Dongargarh
Chhattisgarh
INDIA
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