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Part9
Obstetricsandgynaecology
Antenatalcare
Antepartumhaemorrhage
Diabetesinpregnancy
Ectopicpregnancyandmiscarriage
Hypertensioninpregnancy
Intrapartumcare
Nauseaandvomitinginpregnancy
Pelvicorganprolapseinwomen
Postpartumhaemorrhage
Sepsisinandfollowingpregnancy
Thrombosisandembolismduringpregnancyandthepostnatalperiod
Urinaryincontinenceinwomen
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Chapter57
Antenatalcare
Guideline: NICE NG201 (Antenatal care):
https://www.nice.org.uk/guidance/ng201
OUPdisclaimer:OxfordUniversity Press makesno representation, express
or implied, that the drugdosagesarecorrectand thatthe recommendations
are an exclusive or mandatory course of care. All health professionals
readingthistexthavearesponsibilitytoevaluateitsappropriatenessandtake
theindividualneedsofthepatientintoaccount.
Localtrustguidelines:pleaserefertoyourlocalguidelinesasnecessary.
Overview
This chapter summarizes the antenatal care that should be received by women with
uncomplicated (midwife-led) singleton pregnancies. Women with more complicated
pregnancies should also receive this baseline of care and have additional scans and
appointmentsasrequired.
Antenatalinformation
Thefollowingitemsshouldbediscussed:
Atthefirstcontactwithahealthcareprofessional
Folicacidsupplementation
Reducingtheriskoffood-acquiredinfections
Smokingcessationandavoidingdrugandalcoholuse
Screeningprogrammesincludingrisksandbenefits.
Atbooking
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Fetaldevelopment
Nutritionalinformation,includingvitaminDsupplementation
Exercise,includingpelvicfloorexercises
Placeofbirth
Breastfeeding
Antenatalclasses
Mentalhealthissues.
Beforeorat36weeks
Breastfeeding
Preparationforlabourandbirth,includingpainmanagement
NeonatalvitaminKprophylaxis
Newbornscreeningtests
Postnatalself-care
Recognitionofpostpartumdepression.
At38weeks
Optionsifthepregnancyislikelytobeoverdue.
Antenatalappointments
In anuncomplicated pregnancy, nulliparous womenshould haveten appointments, and
parouswomenshouldhaveseven.SeeTable57.1.
Atallappointments:
Measurebloodpressureandtesturineforproteinuria
Measureandplotsymphysis–fundalheight(after25weeks).
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Table57.1Summaryofantenatalappointments
Gestation Content
Bookingappointment(ideallyby
10weeks)
Takepastmedical,obstetricandfamily history,includingriskfactors forpreeclampsia(seeChapter61)
Identifywomenwhomayneedadditionalcare
CheckFBC,bloodgroup,andrhesusDstatus
Offerscreening
Arrangeultrasoundscansfordatingandanomalies
Measureheight,weight,andBMI
Identifywomenwhohavehadfemalegenitalmutilation(FGM)
Askaboutmoodandpsychiatrichistory
Askaboutoccupationtoidentifypotentialrisks
16weeks
Reviewresultsofscreeningtests
Startironsupplementationifanaemic
25weeks
*
Routine
Discussfetalmovementsandhowtoseekmedicalhelp iftheynotice reduced
fetalmovements
28weeks
Secondscreeningforanaemia,bloodgroup,andatypicalredcellalloantibodies
Anti-Dprophylaxisifrhesusnegative
31weeks
*
Reviewresultsofscreeningtests
34weeks
Seconddoseofanti-Difrhesusnegative
36weeks
Offerexternalcephalicversion(ECV)ifsuspectedbreech
38weeks
Routine
40weeks
*
Routine
41weeks Forwomenwhohavenotgivenbirthby41weeks:
Offeramembranesweep
Offerinductionoflabour.Ifdeclined,offer↑monitoring
*
Signifiesextraappointmentsfornulliparouswomen.
Scanning
10+0–13+6 weeks: dating scan to determine gestational age using crown–rump length
measurement(andcheckformultiplepregnancies)
18+0–20+6weeks: structural anomaly scan to look for congenital abnormalities and placental
position.Iftheplacentaislow,thenare-scanshouldbebookedfor32–36weeks.
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Lifestyleconsiderations
Nutritionalsupplements
Folicacid:400microgramsperday.Ideallyfrom3monthspriortoconceptionandthroughoutthe
first12weekstoreducetheriskofneuraltubedefects
Vitamin D: 10 micrograms per day during pregnancy and breastfeeding. Higher-risk women
includethosewithdarkerskinorlimitedexposuretosunlight(e.g.houseboundorskincoveredfor
culturalreasons)
Iron:notroutinelyofferedasthereisnobenefitifnotanaemicanditmayhavesideeffects
Vitamin A: avoid supplementation (liver/liver products also contain high levels) as it may be
teratogenic.
Sleepingposition
Advisewomennottosleepontheirbackafter28weeks.
Reducingriskofinfection
Listeria
Drinkonlypasteurizedorultra-hightemperature(UHT)milk
Avoideatingripenedsoftcheese,bluecheese,oranypate
Avoideatingundercookedreadymeals.
Salmonella
Avoidraworpartiallycookedeggsorfoodcontainingthem(e.g.mayonnaise)
Avoidraworpartiallycookedmeat,particularlypoultry.
Toxoplasmosis
Washhandsbeforehandlingfood
Washallfruitsandvegetables
Ensureallfoodisthoroughlycookedforconsumption
Wearglovesandwashhandsaftergardening
Avoidtouchingcatfaecesincatlitterorsoil.
Medication
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Fewmedicineshavebeenestablishedassafeforuseinpregnancy
Prescription should be limited to situations where benefit outweighs risk. Over-the-counter
medicinesandcomplementarytherapiesshouldbeavoided.
Exerciseinpregnancy
Moderate-intensityexerciseissafeinpregnancy
Contactandhigh-impactsportswithriskofabdominaltraumaorfallsshouldbeavoided
Scubadivingisunsafe.
Smokinginpregnancy
There is an↑riskofadversepregnancyoutcomes inwomenwhosmokeorwhoareexposedto
second-handsmoke.Theseincludeintrauterinegrowthrestriction,pre-termbirth,andstillbirth
Allwomenshouldhavetheirsmokingstatusexploredandbeofferedsmokingcessationadviceand
referraltolocalNHSStopSmokingServicesifrequired
Therisksandbenefitsofnicotinereplacementtherapyinpregnancyshouldalsobeexplored.
Travelduringpregnancy
Airtravel
Long-haul airtravel isgenerallyassociatedwithan↑riskofDVTandPE.Itisunclearwhether
pregnancyincreasesthisrisk
Wearingcompressionstockingsmayreducetherisk.
Cartravel
Ensurethecorrectuseofseatbelts,i.e.three-pointseatbeltaboveandbelowthebump,notoverit.
Travelabroad
Discussconsiderationssuch asflying(airlinerulesvary),travelinsurance,andvaccinations(not
allvaccinationsaresafeforthefetus).
Managementofcommonpregnancysymptoms
Nauseaandvomitinginearlypregnancy
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SeeChapter63formoredetails
Most cases will resolve by 20 weeks without treatment.It does not affect pregnancy outcome.
First-linetreatmentoptionsinclude:
Ginger
Wristacupressure
Antihistamines.
Heartburn
Considerlifestyleanddietmodification.Antacidscanbetrialled,e.g.ranitidineoromeprazole.
Constipationandhaemorrhoids
Give advice regarding dietary changes such as increasing fibre intake. Consider standard
haemorrhoidcreamsifnecessary.
Varicoseveins
Common,harmless pregnancysymptom. Compressionstockings mayimprove symptoms butwill
notpreventvaricoseveindevelopment.
Vaginaldischarge
↑dischargeisacommonphysiologicalchange.Consideranunderlyinginfectionifitisassociated
withitching,pain,offensivesmell,ordysuria
7 days of topical imidazole should be given for vaginal candidiasis. An alternative is a
clotrimazolepessary(500mg,onceonly)withclotrimazoletopicalcream.Oraltreatmentsshould
notbeused.
Vaginalbleeding
Unexplainedvaginalbleedingafter13weeks:
Offeranti-DifrhesusDnegativeandatriskofisoimmunization
Refertosecondarycare.Thedecisiontoadmitdependsontheriskofplacentalabruptionand
pre-termdelivery,severityofbleeding,andthewoman’sabilitytoreturntosecondarycarein
anemergency
Checkplacentallocationifunknown(?placentapraevia).
Backpain
Backpainiscommoninpregnancyandmaybeeasedbywater-basedexerciseandmassage.
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Screening
Noscreeningiscompulsory,so women should begiven sufficientinformation to make
aninformeddecision.Womenshouldbemonitoredandscreenedforgestationaldiabetes
(seeChapter59)andpre-eclampsia(seeChapter61)throughoutpregnancy.
Anaemia
AFBCshouldbetakenatbookingandat28weekstoscreenforanaemia
Ahaemoglobinconcentrationof<110g/Latbookingor<105g/Lat28weeksshouldbetreatedwith
atrialoforaliron.
Bloodgrouping
A groupand saveandantibodyscreenshould beperformed atbooking andagain at 28 weeks,
irrespectiveofpreviousstatus
AllwomenwhoarerhesusDnegativeshouldbegivenanti-Dprophylaxis
Womenwhohaveclinicallysignificantredcellalloantibodiesshouldbereferredtofetalmedicine
forfurtherinvestigationandmanagement.
Haemoglobinopathies
Preconception counselling and carrier testing should be available to those at high risk of
haemoglobinopathies.
Hypertension
Blood pressure should be measured at every antenatal appointment, as well as a urinalysis to
checkforproteinuria
If >20+0weekswitha firstrecording ofhypertension(≥140/90mmHg), theyshould be seen in
secondarycarewithin24hours
If bloodpressureis≥160/110mmHg,theyshouldbeseenurgentlyinsecondary careonthesame
day
SeeChapter61forfurtherdetails.
Screeningforstructuralanomalies
USSforfetalanomaliesisperformedbetween18+0and20+6weeks.Identifyingfetalanomalies
allows:
Terminationofpregnancy
Preparationforanytreatment,disabilities,orpalliativecare
Planningofbirthinaspecialistcentre.
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ScreeningforDown’ssyndrome
Ideally,screeningshouldbedoneusingthe‘combinedtest’(nuchaltranslucencyplusβHCGplus
pregnancy-associatedplasmaprotein-A(PAPP-A))by13+6weeks
If apatientbookslater,or wherenuchaltranslucencycannotbe measured,offerserumscreening
(tripleorquadrupletest)between15+0and20+0weeks
Theroutineanomalyscanshouldnot beusedfor Down’ssyndrome screening;however,ifthere
aresuspiciousfindingsthewomanshouldbereferredtofetalmedicine.
Screeningforinfections
Earlyscreeningshouldbeofferedfor:
Asymptomaticbacteriuria,syphilis,HIV,andhepatitisB
If<25years,directthewomantothenationalchlamydiascreeningprogramme
Donotscreenfor the following: asymptomatic bacterial vaginosis, cytomegalovirus,hepatitisC
virus,groupBstreptococci,rubella,ortoxoplasmosis.
Furtherreading
1.NHS.TheHealthyStartprogramme.Availableat:https://www.healthystart.nhs.uk/
2.NICE(2014, updated2020). Antenatal andpostnatalmentalhealth:clinical managementandservice
guidance(CG192).Availableat:https://www.nice.org.uk/guidance/cg192
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Chapter58
Antepartumhaemorrhage
Guideline: Royal College of Obstetricians and Gynaecologists (RCOG)
GTG63 (Antepartum haemorrhage): https://www.rcog.org.uk/en/guidelines-
research-services/guidelines/gtg63/
OUPdisclaimer:OxfordUniversity Press makesno representation, express
or implied, that the drugdosagesarecorrectand thatthe recommendations
are an exclusive or mandatory course of care. All health professionals
readingthistexthavearesponsibilitytoevaluateitsappropriatenessandtake
theindividualneedsofthepatientintoaccount.
Localtrustguidelines:pleaserefertoyourlocalguidelinesasnecessary
Overview
Antepartumhaemorrhage(APH)isbleedingfromthegenitaltractbetween24+0weeks’
gestation and birth. It occurs in 3–5% of pregnancies and can affect the morbidityand
mortalityofbothmotherandbaby.
Diagnosis
Causes
Labour
Localbleedingfromthevulva,vagina,orcervix:
Cervicalectropionorpolyp
Infection
Trauma
Malignancy
Placentalabruption
Placentapraevia
Rupturedvasaprevia
Unexplained.
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