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Файл:Ординатура / Хирургия / Библиотека им академика М.И. Перельмана / Книга_3795_Библиотеки_им_академика_М_И_Перельмана-1
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Transcatheter Therapy
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Aortic Valve Replacement in the Management of Adults With Aortic Stenosis: A
Report of the American College of Cardiology Task Force on Clinical Expert
Consensus Documents. J Am Coll Cardiol. 2017;69:1313-1346.
[44] Dvir D, Sagie A, Porat E, Assali A, Shapira Y, Vaknin-Assa H, Shafir G, Bental T,
Nevzorov R, Battler A, Kornowski R. Clinical profile and outcome of patients with
severe aortic stenosis at high surgical risk: single-center prospective evaluation
according to treatment assignment. Catheter Cardiovasc Interv. 2013;81:871-81.
[45] Frerker C, Schewel J, Schlüter M, Schewel D, Ramadan H, Schmidt T, Thielsen T,
Kreidel F, Schlingloff F, Bader R, Wohlmuth P, Schäfer U, Kuck KH. Emergency
transcatheter aortic valve replacement in patients with cardiogenic shock due to acutely
decompensated aortic stenosis. EuroIntervention. 2016;11:1530-6.
[46] Landes U, Orvin K, Codner P, Assali A, Vaknin-Assa H, Schwartznberg S, Levi A,
Shapira Y, Sagie A, Kornowski R. Urgent Transcatheter Aortic Valve Implantation in
Patients With Severe Aortic Stenosis and Acute Heart Failure: Procedural and 30-Day
Outcomes. Can J Cardiol. 2016;32:726-31.
[47] Kolte D, Khera S, Vemulapalli S, Dai D, Heo S, Goldsweig A, Aronow HD, Elmariah
S, Inglessis I, Palacios IF, Thourani VH, Sharaf BL, Gordon PC, Dawn J. Outcomes
Following Urgent/Emergent Transcatheter Aortic Valve Replacement: Insights from the
STS/ACC TVT Registry. J Am Coll Cardiol Intv. 2018;Epub ahead of print.

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ABOUT THE EDITOR
Giovanni Concistrè, MD
Ospedale del Cuore “G. Pasquinucci”,
Fondazione Toscana Gabriele Monasterio, Massa, Italy
Email: gioconci@libero.it
Dr. Giovanni Concistrè is currently an adult cardiac surgeon at the Ospedale del cuore
“G. Pasquinucci”, Massa, Italy. He received his Degree cum laude in Medicine at Perugia
University, discussing the following thesis: “Clinic and echocardiografic follow-up of
patients with the aortic valve replacement with a stentless bioprosthesis Toronto SPV”. His
interest in research developed over the years and when his father underwent surgery for
coronary bypass grafting, he decided that he wanted to pursue a career in cardiac surgery. In
October 2019, he got a Degree cum laude in Cardiac Surgery at Genova University,
discussing the following thesis: “Left ventricular reshaping in ischemic dilated
cardiomyopathy: Genoa’s experience”. In 2010 he worked at Department of Cardiac Surgery
and Heart Transplantation of San Camillo Hospital in Rome and subsequently he became
Assistentarzt at Deutsch Herz Zentrum in Munich and at Klinikum Nurnberg, Germany. From
February 2013 to April 2014, he worked at Clinica S. Anna in Catanzaro, Italy. Concistrè is
the author of numerous publications in scientific journals. He has always been interested in
sutureless aortic bioprostheses, presenting also numerous works at international conferences.
His 2nd Level Master’s degree in “Innovations in Cardiac surgery: advances in minimally
invasive therapeutics” was obtained at Scuola Superiore S. Anna, Pisa. Concistrè is a
Reviewer for Archives of Medical Science, Journal of Thoracic and Cardiovascular Surgery,
Journal of Heart Valve Disease, European Journal of Cardio-Thoracic Surgery. From May
2014, he is cardiac surgeon in Massa, Italy.

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INDEX
A
ACE inhibitors (ACE-I), 84, 229, 240, 242, 243
angiotensin converting enzyme (ACE), 83, 84, 85,
91, 229, 240, 242, 243
angiotensin receptor blockers (ARBs), 84, 89, 237
aortic aneurysm, 9, 29, 179, 188, 193, 199, 201, 256,
337, 360, 364, 379, 384, 385
aortic component of the second heart sound (A2), 17,
22, 28, 29, 146, 231
aortic dissection, 11, 15, 19, 20, 26, 27, 35, 39, 59,
72, 179, 189, 195, 199, 201, 241, 256, 358, 382,
384
aortic operation, 364
aortic regurgitation (AR), xi, 8, 9, 11, 13, 17, 18, 19,
20, 22, 24, 26, 27, 28, 29, 30, 31, 32, 34, 35, 38,
39, 40, 41, 42, 43, 45, 46, 48, 49, 51, 52, 53, 54,
55, 59, 61, 62, 63, 65, 66, 68, 72, 76, 78, 80, 137,
143, 145, 158, 160, 162, 167, 168, 171, 172, 175,
176, 184, 186, 187, 189, 193, 195, 203, 204, 205,
207, 208, 209, 213, 214, 215, 219, 226, 229, 230,
238, 239, 240, 241, 242, 243, 254, 258, 262, 271,
292, 318, 321, 326, 337, 338, 340, 341, 342, 344,
350, 352, 357, 358, 360, 361, 364, 367, 369, 371,
373, 379, 380, 384, 389, 396, 399, 400
aortic repair, 204
aortic root, vii, xi, 1, 3, 4, 5, 7, 8, 9, 13, 17, 20, 22,
27, 28, 29, 38, 39, 44, 46, 47, 53, 55, 57, 60, 61,
67, 68, 69, 70, 72, 76, 80, 88, 97, 109, 110, 111,
113, 120, 145, 160, 161, 166, 169, 170, 181, 185,
196, 207, 208, 209, 229, 241, 242, 243, 254, 256,
263, 272, 274, 276, 278, 279, 280, 283, 293, 301,
316, 320, 326, 329, 332, 338, 339, 340, 342, 343,
344, 345, 347, 350, 359, 360, 361, 363, 364, 365,
366, 367, 368, 369, 371, 373, 374, 375, 376, 377,
378, 379, 382, 383, 384, 385, 387, 390, 396, 404
aortic stenosis (AS), ix, xi, 8, 10, 13, 14, 15, 17, 18,
19, 20, 21, 22, 24, 25, 28, 31, 32, 33, 34, 38, 39,
40, 41, 45, 48, 49, 50, 51, 52, 53, 54, 55, 57, 58,
59, 60, 61, 63, 65, 66, 67, 68, 69, 75, 76, 77, 78,
79, 81, 83, 84, 88, 89, 90, 91, 92, 93, 94, 99, 129,
139, 159, 171, 172, 182, 183, 184, 187, 192, 193,
194, 199, 206, 217, 218, 221, 222, 223, 224, 225,
227, 228, 230, 231, 232, 234, 236, 237, 238, 244,
245, 246, 247, 248, 249, 250, 251, 252, 253, 254,
255, 257, 262, 263, 264, 265, 266, 267, 268, 271,
278, 279, 292, 298, 305, 306, 309, 310, 312, 315,
323, 331, 332, 335, 342, 344, 355, 365, 369, 371,
376, 377, 381, 382, 389, 390, 391, 392, 398, 399,
400, 401, 403, 404, 405, 406, 407
aortic valve degenerative disease, 84
aortic valve disease, 1, iii, vii, viii, ix, xi, 8, 10, 12,
17, 18, 19, 20, 21, 26, 31, 33, 37, 52, 55, 56, 63,
65, 74, 77, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92,
93, 94, 98, 192, 203, 204, 217, 218, 220, 229,
230, 253, 254, 255, 262, 271, 273, 297, 305, 315
aortic valve prosthesis, xi, 217, 259, 264, 273, 313,
315, 318, 334, 336
aortic valve regurgitation, 31, 32, 42, 61, 63, 65, 105,
175, 179, 230, 337, 363, 387
aortic valve replacement (AVR), viii, 17, 18, 19, 20,
23, 25, 30, 31, 32, 56, 68, 69, 72, 73, 79, 80, 108,
111, 121, 164, 172, 182, 183, 184, 185, 187, 193,
194, 195, 198, 201, 203, 207, 212, 215, 217, 219,
226, 227, 228, 229, 231, 238, 240, 241, 242, 243,
253, 254, 265, 266, 267, 268,269, 270, 271, 272,
273, 274, 275, 279, 280, 283, 284, 285, 287, 288,
291, 294, 295, 297, 298, 300, 302, 303, 304, 305,
306, 308, 309, 312, 313, 314, 315, 318, 322, 324,
327, 328, 330, 331, 332, 334, 335, 336, 359, 382,
389, 390, 399, 400, 402, 409

Index
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aortic valve stenosis, 9, 32, 33, 34, 52, 54, 56, 59, 75,
76, 167, 179, 181, 182, 192, 193, 195, 199, 209,
227, 230, 245, 247, 249, 250, 251, 271, 389, 399
aortic-left ventricular tunnel, 145, 165, 166, 177
aortopathy, 10, 11, 14, 20, 67, 179, 180, 181, 187,
188, 189, 190, 191, 195, 198, 199, 200, 201, 291,
350, 379
atrial fibrillation (AF), 17, 21, 25, 34, 258, 284
B
bicuspid aortic valve, viii, 2, 8, 13, 14, 15, 20, 22,
24, 29, 39, 52, 58, 59, 75, 99, 114, 136, 141, 143,
159, 179, 180, 182, 184, 190, 191, 192, 193, 194,
195, 196, 197, 198, 199, 200, 201, 202, 215, 244,
246, 247, 249, 251, 276, 298, 338, 340, 352, 359,
360, 361, 368, 370, 378, 383, 384
Bone morphogenic protein (BMP), 2, 10, 12, 84, 86,
87
B-type natriuretic peptide (BNP), 18, 23, 33, 142
C
calcific aortic valve, 9, 13, 84, 92, 93, 94, 95, 230,
231, 244, 245, 246, 247, 248, 249, 250, 251, 396
calcific aortic valve disease, 9, 13, 92, 93, 94, 95,
230, 244, 245, 246, 247, 248, 249, 250, 251
cardiac endoscopy, 287
cardiac tumors, 63, 77, 125, 126, 130, 131, 133, 134,
135, 138, 140, 142
cardiovascular magnetic resonance (CMR), 55, 56
computed tomography (CT), vii, 4, 8, 18, 23, 27, 47,
48, 51, 52, 53, 55, 56, 60, 61, 64, 66, 67, 68, 69,
70, 71, 72, 73, 75, 76, 77, 79, 80, 83, 88, 103,
104, 110, 117, 125, 126, 127, 129, 130, 131, 133,
134, 138, 140, 142, 182, 184, 196, 215, 233, 234,
244, 246, 247, 249, 251, 256, 280, 290, 291, 299,
300, 301, 318, 321, 322, 323, 333, 335, 363, 365,
368, 375, 383, 384, 385, 396, 401, 402, 406
congenital aortic disease, 145
conventional aortic surgery, 297
conventional aortic valve replacement, 273, 285, 315
coronary artery disease (CAD), 18, 21, 27, 32, 65,
73, 79, 84, 127, 217, 218, 225, 236, 245, 247,
249, 251
E
endocarditis, vii, 8, 9, 11, 19, 20, 24, 25, 26, 27, 34,
38, 44, 46, 48, 64, 97, 98, 99, 100, 101, 102, 104,
105, 107, 108, 109, 110, 111, 112, 113, 114, 115,
116, 117, 118, 119, 120, 121, 122, 123, 126, 135,
137, 141, 143, 179, 183, 184, 186, 195, 197, 198,
242, 259,260, 270, 298, 299, 303, 318, 333, 350,
357, 358, 364
endoscopic cardiac surgery, 287, 295
epidemiology, vii, 17, 18, 31, 34, 97, 98, 99, 114,
137, 157, 183, 230, 244, 246, 248, 250, 251
F
first heart sound (S1), 18, 22, 26, 28
Fluorodeoxyglucose (FDG), 84, 88, 103, 104, 244,
246, 247, 249, 251
fourth heart sound (S4), 18, 22, 26
H
hazard ratio (HR), 18, 19, 141, 154, 271, 401
heart failure (HF), 18, 21, 24, 25, 26, 27, 66, 67, 78,
97, 105, 106, 107, 109, 110, 126, 129, 130, 131,
132, 134, 136, 137, 141, 161, 163, 167, 168, 204,
206, 207, 212, 213, 218, 221, 224, 227, 229, 236,
238, 242, 243, 256, 259, 260, 261, 263, 401, 407
heart team, viii, 217, 218, 220, 221, 222, 223, 224,
225, 257, 390, 400, 402, 406
I
infective valve endocarditis, 179
L
left ventricle (LV), 18, 19, 21, 22, 24, 25, 26, 27, 28,
29, 30, 31, 33, 38, 40, 41, 43, 51, 56, 59, 61, 62,
65, 66, 67, 68, 69, 70, 73, 75, 102, 108, 131, 147,
160, 165, 166, 167, 168, 203, 204, 205, 206, 207,
209, 211, 229, 238, 239, 240, 241, 242, 243, 256,
262, 274, 282,293, 366, 367, 399
left ventricle assist device, 203, 204
low-density lipoprotein (LDL), 8, 13, 84, 86, 87, 88,
90, 92, 93, 231, 232, 233, 235, 244, 246, 248, 250
LV ejection fraction (LVEF), 18, 23, 24, 25, 31, 41,
49, 50, 51, 54, 65, 238, 239, 240, 242, 258, 401
electrocardiogram (ECG), 18, 23, 27, 30, 60, 69, 70,
117, 395

413
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M
magnetic resonance, vii, 10, 18, 23, 24, 33, 52, 55,
56, 69, 74, 75, 76, 77, 78, 79, 80, 81, 88, 107,
116, 125, 126, 181, 190, 191, 199, 363, 375, 386
magnetic resonance imaging (MRI), 10, 33, 52, 63,
74, 75, 76, 77, 78, 79, 81, 107, 116, 125, 126,
167, 181, 188, 190, 199, 256, 363, 375
Matrix Gla protein (MGP), 84, 87, 90, 93
mechanical valves, 122, 258, 259, 260, 261, 305,
310, 333
micro-optical coherence tomography (mOCT), 83,
84, 89, 91
minimally invasive aortic valve replacement, 273,
315
minimally invasive cardiac surgery (MICS), 257,
266, 287, 288, 290, 291, 295
minimally invasive surgery, 256, 279, 290, 297
molecular imaging, 84, 88
morphogenesis, vii, 1, 2, 172, 187
multidetector computed tomography (MDCT), 18,
23, 33, 80, 323
N
N-terminal fraction of pro-BNP (NT-proBNP), 18,
23
O
outcomes, vii, viii, 11, 15, 23, 34, 77, 97, 120, 122,
141, 145, 151, 152, 164, 173, 174, 175, 183, 184,
187, 193, 194, 195, 196, 197, 201, 203, 218, 225,
226, 227, 228, 233, 237, 241, 244, 246, 248, 250,
253, 257, 265, 266, 267, 268, 270, 283, 285, 295,
300, 302,303, 313, 314, 331, 333, 334, 335, 351,
358, 359, 360, 368, 373, 376, 379, 395, 398, 401,
402, 404, 405, 407
P
pathology, vii, 1, 9, 31, 38, 52, 66, 78, 83, 85, 87, 94,
97, 99, 101, 121, 141, 193, 204, 213, 244, 246,
247, 249, 251, 290, 363, 364, 368, 381, 382, 385
percutaneous, 18, 20, 32, 48, 49, 56, 68, 69, 88, 91,
203, 207, 214, 215, 217, 218, 224, 227, 254, 264,
280, 281, 282, 291, 293, 302, 390, 391, 395, 397,
398, 400, 402, 403, 406
Peroxisome proliferator-activator γ (PPARγ), 84, 90,
235
pharmacological treatment, viii, 229, 230, 238
Phosphate Pi, 75, 84, 86, 87, 235
positron emission tomography (PET), 18, 56, 84, 88,
91, 93, 103, 104, 110, 117, 234, 244, 246, 247,
249, 251
pulmonic component of the second heart sound (P2),
18, 22, 26, 29
R
ramp test, 204, 206
reactive oxygen species (ROS), 84, 85
Receptor activator of nuclear factor kappa
(B RANK), 87
Receptor activator of nuclear factor kappa B ligand
(RANKL), 84, 90
reintervention, 154, 155, 156, 171, 297, 357
repair techniques, 148, 163, 185, 303, 337, 338, 341,
349
Rosuvastatin affecting aortic valve endothelium
(RAAVE), 84, 89, 94
S
second heart sound (S2), 18, 21, 26, 29, 167
sodium fluoride (NaF), 84, 88, 93
sparing techniques, 337, 386
sudden cardiac death (SCD), 18, 25
surgical anatomy, vii, 1, 13, 365
surgical aortic valve replacement, 56, 79, 194, 218,
219, 222, 253, 255, 267, 303, 304, 309, 315, 390,
406
surgical treatment, viii, 98, 105, 108, 119, 121, 122,
138, 157, 164, 184, 186, 197, 198, 229, 253, 254,
255, 264, 303, 305, 331, 335, 385, 400
sutured biological valves, viii, 305
T
third heart sound (S3), 18, 26, 29
tissue engineering, 12, 84, 90, 92, 95
tissue engineering of heart valves (TEHV), 84, 91
transapical, 68, 91, 217, 254, 264, 392, 393, 397, 401
transcatheter aortic valve, xi, 17, 18, 23, 34, 52, 56,
76, 79, 80, 81, 83, 90, 91, 114, 122, 194, 195,
204, 207, 214, 215, 217, 218, 219, 222, 225, 226,
227, 228, 229, 253, 265, 266, 267, 298, 304, 316,
321, 323, 330, 334, 336, 383, 389, 392, 403, 404,
405, 407
transcatheter aortic valve implantation (TAVI), 18,
23, 25, 31, 34, 56, 68, 69, 70, 76, 79, 80, 83, 90,
91, 111, 122, 227, 228, 229, 238, 253, 256, 257,

Index
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265, 266, 267, 298, 304, 315, 321, 323, 334, 336,
389, 390, 391, 392, 394, 395, 396, 397, 398, 399,
400, 401, 403, 404, 405, 407
trans-esophageal and stress echocardiography, 37
transesophageal echocardiogram (TEE), 18, 23, 27,
38, 43, 44, 45, 46, 47, 48, 63, 102, 103, 110, 126,
127, 130, 133, 136, 137, 138, 282, 292, 330, 368,
369, 376
transfemoral aortic valve implantation, 253, 404
trans-thoracic, vii, 37, 38, 127
transthoracic echocardiogram (TTE), 18, 22, 25, 29,
30, 31, 38, 45, 46, 48, 61, 64, 69, 71, 72, 73, 103,
110, 126, 127, 129, 130, 133, 137, 184, 280, 333
truncus arteriosus, 145, 146, 147, 148, 151, 155, 156,
167, 172, 173, 174
V
valvular disease, 28, 49, 56, 60, 67, 69, 78, 214, 217,
269, 273, 315
ventricular septal defect, 34, 59, 100, 108, 145, 146,
147, 156, 169, 173, 174, 175, 176

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